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Ophthalmology

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 53 articles: HTML format

Single Articles

June 2026
1. LY K, Bhuckory MB, Pham-Howard D, Kochnev Goldstein A, et al
   Residual photoreceptors affect the response of a degenerate retina to electrical stimulation.
   Proc Natl Acad Sci U S A. 2026;123:e2537064123.
   PubMed     Abstract available
   
   
   May 2026
2. GOMEZ-SINTES R, Tasset I, Ramirez-Pardo I, Martin-Segura A, et al
   Chaperone-mediated autophagy protects against retinal photoreceptor degeneration by modulating proteostasis of glucose metabolism enzymes.
   Proc Natl Acad Sci U S A. 2026;123:e2527503123.
   PubMed     Abstract available
   
   
   
3. BERNSTEIN SL, Mehrabian Z, Guo Y, Jouffroy J, et al
   Hopx(+) optic nerve head-astrocytes counter neuronal stress and glaucoma damage.
   Proc Natl Acad Sci U S A. 2026;123:e2515277123.
   PubMed     Abstract available
   
   
   April 2026
4. JAGGERS TN, Ripolles-Garcia A, Moshiri A, Story BD, et al
   Rhesus macaques with an OPA1 mutation demonstrate features of autosomal dominant optic atrophy.
   Proc Natl Acad Sci U S A. 2026;123:e2509165123.
   PubMed     Abstract available
   
   
   
5. BRILLANTE S, Volpe M, Diana A, Negueruela S, et al
   Uncovering mitochondrial defects in photoreceptors opens therapeutic opportunities for Stargardt disease.
   Proc Natl Acad Sci U S A. 2026;123:e2504764123.
   PubMed     Abstract available
   
   
   February 2026
6. LI Y, Jing M, Wang W, Lin W, et al
   DAPL1 restrains RPE PANoptosis in experimental AMD by inhibiting GRP75-mediated mitochondria-associated endoplasmic reticulum membranes.
   Proc Natl Acad Sci U S A. 2026;123:e2511926123.
   PubMed     Abstract available
   
   
   
7. CUI T, Wen Q, An Z, Kang J, et al
   Natalizumab exacerbates astrocytopathy in NMOSD via blockade of endothelial VCAM1-astrocytic integrin alpha4 interaction.
   Proc Natl Acad Sci U S A. 2026;123:e2520566123.
   PubMed     Abstract available
   
   
   
8. WANG X, Jing X, Guo Z, Long S, et al
   Coviretinopathy: COVID-19-induced VEGF-dependent retinopathy.
   Proc Natl Acad Sci U S A. 2026;123:e2516405123.
   PubMed     Abstract available
   
   
   January 2026
9. SINGH KK, Jin Y, Hu MW, Palazzo I, et al
   Molecular underpinnings of induced degenerative heterogeneity in the retinal pigment epithelium.
   Proc Natl Acad Sci U S A. 2026;123:e2505412123.
   PubMed     Abstract available
   
   
   December 2025
10. RIAHI Z, Boucher S, Abdi S, Wong Jun Tai F, et al
    Genetics of prelingual isolated deafness and Usher syndrome in the Maghreb and Jordan: Harnessing the potential of homozygosity.
    Proc Natl Acad Sci U S A. 2025;122:e2518445122.
    PubMed     Abstract available
    
    
    November 2025
11. WANG S, Li M, Chen G, Chen Z, et al
    Joubert syndrome 26 protein enforces compartmentalized motility of a ciliary kinesin.
    Proc Natl Acad Sci U S A. 2025;122:e2504374122.
    PubMed     Abstract available
    
    
    
12. SHEN W, Nie Z, Wang M, Zhang H, et al
    Monocyte-derived exosomal periostin driven by histone lactylation contributes to retinal neovascularization.
    Proc Natl Acad Sci U S A. 2025;122:e2501704122.
    PubMed     Abstract available
    
    
    October 2025
13. SOTANI N, Kusuhara S, Nishisho R, Kuno H, et al
    Transpupillary in vivo two-photon imaging reveals enhanced surveillance of retinal microglia in diabetic mice.
    Proc Natl Acad Sci U S A. 2025;122:e2426241122.
    PubMed     Abstract available
    
    
    September 2025
14. MA E, Schafer CM, Xie J, Rudenko Y, et al
    Targeting endothelial ERG to mitigate vascular regression in retinopathies.
    Proc Natl Acad Sci U S A. 2025;122:e2507194122.
    PubMed     Abstract available
    
    
    
15. STANHOPE SC, Singhal K, Morato NM, Feng Y, et al
    Drosophila Ahcy is a redox sensor that modulates gene expression to protect against light stress-induced retinal degeneration.
    Proc Natl Acad Sci U S A. 2025;122:e2511388122.
    PubMed     Abstract available
    
    
    
16. WANG J, Zhou C, Zhuang K, Zou J, et al
    Sorting nexin 3 promotes ischemic retinopathy through RIP1- and RIP3-mediated myeloid cell necroptosis and mitochondrial fission.
    Proc Natl Acad Sci U S A. 2025;122:e2426578122.
    PubMed     Abstract available
    
    
    
17. GOMES C, Huang KC, Lavekar SS, Harkin J, et al
    Modeling human retinal ganglion cell axonal outgrowth, development, and pathology using pluripotent stem cell-based microfluidic platforms.
    Proc Natl Acad Sci U S A. 2025;122:e2423682122.
    PubMed     Abstract available
    
    
    
18. LIAO M, Ye Z, Zhao Y, Nan J, et al
    Single-cell transcriptome combined with genetic tracing reveals a roadmap of fibrosis formation during proliferative vitreoretinopathy.
    Proc Natl Acad Sci U S A. 2025;122:e2424487122.
    PubMed     Abstract available
    
    
    August 2025
19. HUANG Y, Lin H, Shi J, Chen Y, et al
    Serum metabolic patterns reveal the diagnostic and prognostic role of alanine abnormality in ocular adnexal lymphoma.
    Proc Natl Acad Sci U S A. 2025;122:e2506345122.
    PubMed     Abstract available
    
    
    July 2025
20. WANG Z, Anderson DMG, Messinger JD, Curcio CA, et al
    Glycolipids implicated as mediators of clinically visible retinal pigment epithelial migration in age-related macular degeneration.
    Proc Natl Acad Sci U S A. 2025;122:e2503191122.
    PubMed     Abstract available
    
    
    June 2025
21. TOOMEY CB, Pflugmacher S, Park K, Pihl J, et al
    Bruch's membrane heparan sulfate retains lipoproteins in the early stages of age-related macular degeneration.
    Proc Natl Acad Sci U S A. 2025;122:e2500727122.
    PubMed     Abstract available
    
    
    
22. WANG Y, Zhang YC, Ding ZQ, Xu SY, et al
    Feedback regulation between histone lactylation and ALKBH3-mediated glycolysis regulates age-related macular degeneration pathology.
    Proc Natl Acad Sci U S A. 2025;122:e2416046122.
    PubMed     Abstract available
    
    
    May 2025
23. MURPHY DP, Kolesnikov AV, Montana CL, Khaja ZM, et al
    Mechanisms of photoreceptor protection upon targeting the Nrl-Nr2e3 pathway.
    Proc Natl Acad Sci U S A. 2025;122:e2500446122.
    PubMed     Abstract available
    
    
    
24. JUN DJ, Schumacher MM, Jo Y, Faulkner RA, et al
    Allosteric regulation of UBIAD1 trafficking from ER to Golgi revealed by chemical genetic screening.
    Proc Natl Acad Sci U S A. 2025;122:e2426532122.
    PubMed     Abstract available
    
    
    
25. ZHANG J, Yang W, Wu J, Lin B, et al
    Understanding TAK1 deficiency in microglia: Dual mechanisms for photoreceptor protection in a mouse model of retinitis pigmentosa.
    Proc Natl Acad Sci U S A. 2025;122:e2423134122.
    PubMed     Abstract available
    
    
    
26. MARTIN M, Bolognesi B
    Massive mutagenesis reveals an incomplete amyloid motif in Bri2 that turns amyloidogenic upon C-terminal extension.
    Proc Natl Acad Sci U S A. 2025;122:e2415521122.
    PubMed     Abstract available
    
    
    April 2025
27. TWORAK A, Smidak R, Rodrigues Menezes C, Du SW, et al
    MFRP is a molecular hub that organizes the apical membrane of RPE cells by engaging in interactions with specific proteins and lipids.
    Proc Natl Acad Sci U S A. 2025;122:e2425523122.
    PubMed     Abstract available
    
    
    
28. CHANDLER LC, Gardner A, Cepko CL
    RPE-specific MCT2 expression promotes cone survival in models of retinitis pigmentosa.
    Proc Natl Acad Sci U S A. 2025;122:e2421978122.
    PubMed     Abstract available
    
    
    March 2025
29. COOPER ML, Gildea HK, Selles MC, Katafygiotou E, et al
    Astrocytes in the mouse brain respond bilaterally to unilateral retinal neurodegeneration.
    Proc Natl Acad Sci U S A. 2025;122:e2418249122.
    PubMed     Abstract available
    
    
    
30. DVORIANTCHIKOVA G, Moulin C, Fleishaker M, Almeida V, et al
    Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness.
    Proc Natl Acad Sci U S A. 2025;122:e2420091122.
    PubMed     Abstract available
    
    
    February 2025
31. VOLZ S, Malone JR, Guseman AJ, Gronenborn AM, et al
    Cataract-prone variants of gammaD-crystallin populate a conformation with a partially unfolded N-terminal domain under native conditions.
    Proc Natl Acad Sci U S A. 2025;122:e2410860122.
    PubMed     Abstract available
    
    
    January 2025
32. BISWAS N, Mori T, Ragava Chetty Nagaraj NK, Xin H, et al
    Adenosine diphosphate stimulates VEGF-independent choroidal endothelial cell proliferation: A potential escape from anti-VEGF therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2418752122.
    PubMed     Abstract available
    
    
    
33. BUTENKO K, Neudorfer C, Dembek TA, Hollunder B, et al
    Engaging dystonia networks with subthalamic stimulation.
    Proc Natl Acad Sci U S A. 2025;122:e2417617122.
    PubMed     Abstract available
    
    
    December 2024
34. HATA M, Hata M, Dejda A, Pilon F, et al
    Corticosteroids reduce pathological angiogenesis yet compromise reparative vascular remodeling in a model of retinopathy.
    Proc Natl Acad Sci U S A. 2024;121:e2411640121.
    PubMed     Abstract available
    
    
    
35. HILDEBRANDT M, Kotewitsch M, Kaupp S, Salomon S, et al
    Stabilizing selection in an identified multisensory neuron in blind cavefish.
    Proc Natl Acad Sci U S A. 2024;121:e2415854121.
    PubMed     Abstract available
    
    
    
36. PATEL A, Pauzuolyte V, Ingham NJ, Leong YC, et al
    Rescue of cochlear vascular pathology prevents sensory hair cell loss in Norrie disease.
    Proc Natl Acad Sci U S A. 2024;121:e2322124121.
    PubMed     Abstract available
    
    
    November 2024
37. WEI Z, Hao C, Radeen KR, Hao Z, et al
    Deficiency in glutathione peroxidase 4 (GPX4) results in abnormal lens development and newborn cataract.
    Proc Natl Acad Sci U S A. 2024;121:e2407842121.
    PubMed     Abstract available
    
    
    
38. VEREERTBRUGGHEN A, Pizzano M, Cernutto A, Sabbione F, et al
    CD4(+) T cells drive corneal nerve damage but not epitheliopathy in an acute aqueous-deficient dry eye model.
    Proc Natl Acad Sci U S A. 2024;121:e2407648121.
    PubMed     Abstract available
    
    
    
39. DU SW, Newby GA, Salom D, Gao F, et al
    In vivo photoreceptor base editing ameliorates rhodopsin-E150K autosomal-recessive retinitis pigmentosa in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2416827121.
    PubMed     Abstract available
    
    
    
40. SHARMA D, Lau E, Qin Y, Jee K, et al
    VEGF inhibition increases expression of HIF-regulated angiogenic genes by the RPE limiting the response of wet AMD eyes to aflibercept.
    Proc Natl Acad Sci U S A. 2024;121:e2322759121.
    PubMed     Abstract available
    
    
    October 2024
41. CHANG D, Caterina MJ
    Pinning down a perpetrator in postsurgical eye pain.
    Proc Natl Acad Sci U S A. 2024;121:e2417221121.
    PubMed    
    
    
    
42. PATHAK V, Bertelli PM, Pedrini E, Harkin K, et al
    Modulation of diabetes-related retinal pathophysiology by PTX3.
    Proc Natl Acad Sci U S A. 2024;121:e2320034121.
    PubMed     Abstract available
    
    
    September 2024
43. LI W, He S, Tan J, Li N, et al
    Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype.
    Proc Natl Acad Sci U S A. 2024;121:e2316161121.
    PubMed     Abstract available
    
    
    
44. LIU Y, Wang A, Chen C, Zhang Q, et al
    Microglial cGAS-STING signaling underlies glaucoma pathogenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2409493121.
    PubMed     Abstract available
    
    
    August 2024
45. AMARAL L, Thomas P, Amedi A, Striem-Amit E, et al
    Longitudinal stability of individual brain plasticity patterns in blindness.
    Proc Natl Acad Sci U S A. 2024;121:e2320251121.
    PubMed     Abstract available
    
    
    July 2024
46. BORKAR S, Baumli P, Vance T, Sharma E, et al
    Elucidating the roles of electrolytes and hydrogen bonding in the dewetting dynamics of the tear film.
    Proc Natl Acad Sci U S A. 2024;121:e2407501121.
    PubMed     Abstract available
    
    
    June 2024
47. CHEN M, Wang Y, Dalal R, Du J, et al
    Alternative oxidase blunts pseudohypoxia and photoreceptor degeneration due to RPE mitochondrial dysfunction.
    Proc Natl Acad Sci U S A. 2024;121:e2402384121.
    PubMed     Abstract available
    
    
    May 2024
48. GOTO S, Tsutsumi A, Lee Y, Hosojima M, et al
    Cryo-EM structures elucidate the multiligand receptor nature of megalin.
    Proc Natl Acad Sci U S A. 2024;121:e2318859121.
    PubMed     Abstract available
    
    
    
49. FAIN GL
    The mechanism of genetically inherited night blindness.
    Proc Natl Acad Sci U S A. 2024;121:e2408254121.
    PubMed    
    
    
    
50. CHAI Z, Ye Y, Silverman D, Rose K, et al
    Dark continuous noise from mutant G90D-rhodopsin predominantly underlies congenital stationary night blindness.
    Proc Natl Acad Sci U S A. 2024;121:e2404763121.
    PubMed     Abstract available
    
    
    April 2024
51. LIU Y, Liu X, Chen X, Yang Z, et al
    Senolytic and senomorphic agent procyanidin C1 alleviates structural and functional decline in the aged retina.
    Proc Natl Acad Sci U S A. 2024;121:e2311028121.
    PubMed     Abstract available
    
    
    March 2024
52. KOLESNIKOV AV, Murphy DP, Corbo JC, Kefalov VJ, et al
    Germline knockout of Nr2e3 protects photoreceptors in three distinct mouse models of retinal degeneration.
    Proc Natl Acad Sci U S A. 2024;121:e2316118121.
    PubMed     Abstract available
    
    
    
53. KOJIMA Y, Ito RK, Fukuyama I, Ohkubo Y, et al
    Foraging predicts the evolution of warning coloration and mimicry in snakes.
    Proc Natl Acad Sci U S A. 2024;121:e2318857121.
    PubMed     Abstract available
    
    

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