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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 71 articles:
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Single Articles


    August 2022
  1. CAI J, Litwin C, Cheng R, Ma JX, et al
    DARPP32, a target of hyperactive mTORC1 in the retinal pigment epithelium.
    Proc Natl Acad Sci U S A. 2022;119:e2207489119.
    PubMed     Abstract available


  2. BARISANO G, Tomilovskaya E, Roberts DR, Wuyts FL, et al
    Reply to Wostyn et al.: Potential models for perivascular space (PVS) enlargement and spaceflight-associated neuro-ocular syndrome (SANS).
    Proc Natl Acad Sci U S A. 2022;119:e2208241119.
    PubMed    


  3. FALCON KT, Watt KEN, Dash S, Zhao R, et al
    Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development.
    Proc Natl Acad Sci U S A. 2022;119:e2116974119.
    PubMed     Abstract available


    July 2022
  4. VAN ZYL T, Yan W, McAdams AM, Monavarfeshani A, et al
    Cell atlas of the human ocular anterior segment: Tissue-specific and shared cell types.
    Proc Natl Acad Sci U S A. 2022;119:e2200914119.
    PubMed     Abstract available


  5. YAO PL, Parmar VM, Choudhary M, Malek G, et al
    NURR1 expression regulates retinal pigment epithelial-mesenchymal transition and age-related macular degeneration phenotypes.
    Proc Natl Acad Sci U S A. 2022;119:e2202256119.
    PubMed     Abstract available


  6. SINGH HP, Shayler DWH, Fernandez GE, Thornton ME, et al
    An immature, dedifferentiated, and lineage-deconstrained cone precursor origin of N-Myc-initiated retinoblastoma.
    Proc Natl Acad Sci U S A. 2022;119:e2200721119.
    PubMed     Abstract available


  7. WISSINGER B, Baumann B, Buena-Atienza E, Ravesh Z, et al
    The landscape of submicroscopic structural variants at the OPN1LW/OPN1MW gene cluster on Xq28 underlying blue cone monochromacy.
    Proc Natl Acad Sci U S A. 2022;119:e2115538119.
    PubMed     Abstract available


    June 2022
  8. ZHENG W, Wang X, Liu J, Yu X, et al
    Single-cell analyses highlight the proinflammatory contribution of C1q-high monocytes to Behcet's disease.
    Proc Natl Acad Sci U S A. 2022;119:e2204289119.
    PubMed     Abstract available


  9. DAMATO V, Theorell J, Al-Diwani A, Kienzler AK, et al
    Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders.
    Proc Natl Acad Sci U S A. 2022;119:e2121804119.
    PubMed     Abstract available


    May 2022
  10. JIANG X, Xu Z, Soorma T, Tariq A, et al
    Electrical responses from human retinal cone pathways associate with a common genetic polymorphism implicated in myopia.
    Proc Natl Acad Sci U S A. 2022;119:e2119675119.
    PubMed     Abstract available


  11. MCHARG S, Booth L, Perveen R, Riba Garcia I, et al
    Mast cell infiltration of the choroid and protease release are early events in age-related macular degeneration associated with genetic risk at both chromosomes 1q32 and 10q26.
    Proc Natl Acad Sci U S A. 2022;119:e2118510119.
    PubMed     Abstract available


  12. ZOHARY E, Harari D, Ullman S, Ben-Zion I, et al
    Gaze following requires early visual experience.
    Proc Natl Acad Sci U S A. 2022;119:e2117184119.
    PubMed     Abstract available


  13. ORTOLAN D, Sharma R, Volkov A, Maminishkis A, et al
    Single-cell-resolution map of human retinal pigment epithelium helps discover subpopulations with differential disease sensitivity.
    Proc Natl Acad Sci U S A. 2022;119:e2117553119.
    PubMed     Abstract available


  14. PHELPS GB, Hagen HR, Amsterdam A, Lees JA, et al
    MITF deficiency accelerates GNAQ-driven uveal melanoma.
    Proc Natl Acad Sci U S A. 2022;119:e2107006119.
    PubMed     Abstract available


    April 2022
  15. BARISANO G, Sepehrband F, Collins HR, Jillings S, et al
    The effect of prolonged spaceflight on cerebrospinal fluid and perivascular spaces of astronauts and cosmonauts.
    Proc Natl Acad Sci U S A. 2022;119:e2120439119.
    PubMed     Abstract available


  16. TU J, Huo Z, Yu Y, Zhu D, et al
    Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies.
    Proc Natl Acad Sci U S A. 2022;119:e2117857119.
    PubMed     Abstract available


  17. JOFRE DM, Hoffman DK, Cervino AS, Hahn GM, et al
    The CHARGE syndrome ortholog CHD-7 regulates TGF-beta pathways in Caenorhabditis elegans.
    Proc Natl Acad Sci U S A. 2022;119:e2109508119.
    PubMed     Abstract available


  18. GUO D, Ru J, Xie L, Wu M, et al
    Tmem138 is localized to the connecting cilium essential for rhodopsin localization and outer segment biogenesis.
    Proc Natl Acad Sci U S A. 2022;119:e2109934119.
    PubMed     Abstract available


  19. XIE L, Cen LP, Li Y, Gilbert HY, et al
    Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells' response to Pten deletion.
    Proc Natl Acad Sci U S A. 2022;119:e2113751119.
    PubMed     Abstract available


    March 2022
  20. MIYADERA K, Santana E, Roszak K, Iffrig S, et al
    Targeting ON-bipolar cells by AAV gene therapy stably reverses LRIT3-congenital stationary night blindness.
    Proc Natl Acad Sci U S A. 2022;119:e2117038119.
    PubMed     Abstract available


  21. WANG Y, Punzo C, Ash JD, Lobanova ES, et al
    Tsc2 knockout counteracts ubiquitin-proteasome system insufficiency and delays photoreceptor loss in retinitis pigmentosa.
    Proc Natl Acad Sci U S A. 2022;119:e2118479119.
    PubMed     Abstract available


  22. WU W, Takahashi Y, Shin HY, Ma X, et al
    The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation.
    Proc Natl Acad Sci U S A. 2022;119:e2115202119.
    PubMed     Abstract available


  23. SARRAZIN N, Chavret-Reculon E, Bachelin C, Felfli M, et al
    Failed remyelination of the nonhuman primate optic nerve leads to axon degeneration, retinal damages, and visual dysfunction.
    Proc Natl Acad Sci U S A. 2022;119:e2115973119.
    PubMed     Abstract available


  24. PALKO SI, Saba NJ, Mullane E, Nicholas BD, et al
    Compartmentalized citrullination in Muller glial endfeet during retinal degeneration.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    February 2022
  25. ALARCON-MARTINEZ L, Shiga Y, Villafranca-Baughman D, Belforte N, et al
    Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  26. FERNANDO R, Caldera O, Smith TJ
    Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  27. VAN DER VAART J, Bosmans L, Sijbesma SF, Knoops K, et al
    Adult mouse and human organoids derived from thyroid follicular cells and modeling of Graves' hyperthyroidism.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  28. MILLS SA, Jobling AI, Dixon MA, Bui BV, et al
    Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  29. LASSOUED A, Zhang F, Kurokawa K, Liu Y, et al
    Cone photoreceptor dysfunction in retinitis pigmentosa revealed by optoretinography.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  30. CHOI JK, Yu CR, Bing SJ, Jittayasothorn Y, et al
    IL-27-producing B-1a cells suppress neuroinflammation and CNS autoimmune diseases.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  31. PAN C, Banerjee K, Lehmann GL, Almeida D, et al
    Lipofuscin causes atypical necroptosis through lysosomal membrane permeabilization.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  32. PAN M, Zhao F, Xie B, Wu H, et al
    Dietary omega-3 polyunsaturated fatty acids are protective for myopia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  33. KUTSYR O, Noailles A, Martinez-Gil N, Maestre-Carballa L, et al
    Short-term high-fat feeding exacerbates degeneration in retinitis pigmentosa by promoting retinal oxidative stress and inflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  34. AMBATI M, Apicella I, Wang SB, Narendran S, et al
    Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  35. KROEGER H, Grandjean JMD, Chiang WJ, Bindels DD, et al
    ATF6 is essential for human cone photoreceptor development.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  36. SUN WY, Xue B, Liu YX, Zhang RK, et al
    Chlamydomonas LZTFL1 mediates phototaxis via controlling BBSome recruitment to the basal body and its reassembly at the ciliary tip.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  37. KIM JS, Aheimer B, Montane Manrara V, Bedny M, et al
    Shared understanding of color among sighted and blind adults.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  38. WILLIAMS BL, Seager NA, Gardiner JD, Pappas CM, et al
    Chromosome 10q26-driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  39. CEN LP, Ng TK, Liang JJ, Xu C, et al
    Agonist of growth hormone-releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  40. LEVENTEA E, Zhu Z, Fang X, Nikolaeva Y, et al
    Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  41. JIANG X, Pardue MT, Mori K, Ikeda SI, et al
    Violet light suppresses lens-induced myopia via neuropsin (OPN5) in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  42. HILLA AM, Baehr A, Leibinger M, Andreadaki A, et al
    CXCR4/CXCL12-mediated entrapment of axons at the injury site compromises optic nerve regeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  43. LEACH LL, Hanovice NJ, George SM, Gabriel AE, et al
    The immune response is a critical regulator of zebrafish retinal pigment epithelium regeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  44. XIN H, Biswas N, Li P, Zhong C, et al
    Heparin-binding VEGFR1 variants as long-acting VEGF inhibitors for treatment of intraocular neovascular disorders.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  45. KOOK S, Wang P, Meng S, Jetter CS, et al
    AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  46. FORMOSA LE, Reljic B, Sharpe AJ, Hock DH, et al
    Optic atrophy-associated TMEM126A is an assembly factor for the ND4-module of mitochondrial complex I.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  47. ACKER N, Smith H, Devine C, Oltjen SL, et al
    A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  48. PATEL PD, Chen YL, Kasetti RB, Maddineni P, et al
    Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  49. SHIM MS, Nettesheim A, Dixon A, Liton PB, et al
    Primary cilia and the reciprocal activation of AKT and SMAD2/3 regulate stretch-induced autophagy in trabecular meshwork cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  50. CAI S, Li H, Zheng F, Kong F, et al
    Artificial intelligence velocimetry and microaneurysm-on-a-chip for three-dimensional analysis of blood flow in physiology and disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  51. HE C, Liu Y, Huang Z, Yang Z, et al
    A specific RIP3(+) subpopulation of microglia promotes retinopathy through a hypoxia-triggered necroptotic mechanism.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  52. XIE L, Yin Y, Benowitz L
    Chemokine CCL5 promotes robust optic nerve regeneration and mediates many of the effects of CNTF gene therapy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  53. FUKUDA S, Varshney A, Fowler BJ, Wang SB, et al
    Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  54. SINHA T, Du J, Makia MS, Hurley JB, et al
    Absence of retbindin blocks glycolytic flux, disrupts metabolic homeostasis, and leads to photoreceptor degeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  55. GORUSUPUDI A, Rallabandi R, Li B, Arunkumar R, et al
    Retinal bioavailability and functional effects of a synthetic very-long-chain polyunsaturated fatty acid in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  56. PATEL AK, Broyer RM, Lee CD, Lu T, et al
    Inhibition of GCK-IV kinases dissociates cell death and axon regeneration in CNS neurons.
    Proc Natl Acad Sci U S A. 2020;117:33597-33607.
    PubMed     Abstract available


  57. HARDER JM, Guymer C, Wood JPM, Daskalaki E, et al
    Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin.
    Proc Natl Acad Sci U S A. 2020;117:33619-33627.
    PubMed     Abstract available


  58. LI S, Gordon WC, Bazan NG, Jin M, et al
    Inverse correlation between fatty acid transport protein 4 and vision in Leber congenital amaurosis associated with RPE65 mutation.
    Proc Natl Acad Sci U S A. 2020;117:32114-32123.
    PubMed     Abstract available


  59. LIU H, Zhang Y, Zhang YY, Li YP, et al
    Human embryonic stem cell-derived organoid retinoblastoma reveals a cancerous origin.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2011780117.
    PubMed     Abstract available


  60. ATILGAN N, Xiong YZ, Legge GE
    Reconciling print-size and display-size constraints on reading.
    Proc Natl Acad Sci U S A. 2020;117:30276-30284.
    PubMed     Abstract available


  61. HAMMER DX, Agrawal A, Villanueva R, Saeedi O, et al
    Label-free adaptive optics imaging of human retinal macrophage distribution and dynamics.
    Proc Natl Acad Sci U S A. 2020;117:30661-30669.
    PubMed     Abstract available


    November 2020
  62. CHEMELLO F, Wang Z, Li H, McAnally JR, et al
    Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing.
    Proc Natl Acad Sci U S A. 2020;117:29691-29701.
    PubMed     Abstract available


  63. YAN S, Thienthanasit R, Chen D, Engelen E, et al
    CHD7 regulates cardiovascular development through ATP-dependent and -independent activities.
    Proc Natl Acad Sci U S A. 2020;117:28847-28858.
    PubMed     Abstract available


  64. USUI-OUCHI A, Aguilar E, Murinello S, Prins M, et al
    An allosteric peptide inhibitor of HIF-1alpha regulates hypoxia-induced retinal neovascularization.
    Proc Natl Acad Sci U S A. 2020;117:28297-28306.
    PubMed     Abstract available


    September 2020
  65. HU Y, Hu Y, Xiao Y, Wen F, et al
    Genetic landscape and autoimmunity of monocytes in developing Vogt-Koyanagi-Harada disease.
    Proc Natl Acad Sci U S A. 2020 Sep 28. pii: 2002476117.
    PubMed     Abstract available


  66. SILVERMAN D, Chai Z, Yue WWS, Ramisetty SK, et al
    Dark noise and retinal degeneration from D190N-rhodopsin.
    Proc Natl Acad Sci U S A. 2020;117:23033-23043.
    PubMed     Abstract available


  67. PALCZEWSKA G, Boguslawski J, Stremplewski P, Kornaszewski L, et al
    Noninvasive two-photon optical biopsy of retinal fluorophores.
    Proc Natl Acad Sci U S A. 2020;117:22532-22543.
    PubMed     Abstract available


    August 2020
  68. BERNSTEIN SL, Guo Y, Kerr C, Fawcett RJ, et al
    The optic nerve lamina region is a neural progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020;117:19287-19298.
    PubMed     Abstract available


  69. ZUCKER CL, Bernstein PS, Schalek RL, Lichtman JW, et al
    A connectomics approach to understanding a retinal disease.
    Proc Natl Acad Sci U S A. 2020;117:18780-18787.
    PubMed     Abstract available


  70. COOPER ML, Pasini S, Lambert WS, D'Alessandro KB, et al
    Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress.
    Proc Natl Acad Sci U S A. 2020;117:18810-18821.
    PubMed     Abstract available


  71. SHIN K, Kent JE, Singh C, Fujimoto LM, et al
    Calcium and hydroxyapatite binding site of human vitronectin provides insights to abnormal deposit formation.
    Proc Natl Acad Sci U S A. 2020;117:18504-18510.
    PubMed     Abstract available


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