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Articles published in PLoS Pathog

Retrieve available abstracts of 76 articles:
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Single Articles


    September 2018
  1. AHMED A, Adiga V, Nayak S, Uday Kumar JAJ, et al
    Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis.
    PLoS Pathog. 2018;14:e1007289.
    PubMed     Text format     Abstract available


  2. BACHTEL ND, Umviligihozo G, Pickering S, Mota T, et al
    HLA-C downregulation by HIV-1 adapts to host HLA genotype.
    PLoS Pathog. 2018;14:e1007257.
    PubMed     Text format     Abstract available


    August 2018
  3. CHAUDHARY O, Narayan V, Lelis F, Linz B, et al
    Inhibition of p38MAPK in combination with ART reduces SIV-induced immune activation and provides additional protection from immune system deterioration.
    PLoS Pathog. 2018;14:e1007268.
    PubMed     Text format     Abstract available


  4. LERTJUTHAPORN S, Cicala C, Van Ryk D, Liu M, et al
    Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha4beta7.
    PLoS Pathog. 2018;14:e1007278.
    PubMed     Text format     Abstract available


  5. NGANOU-MAKAMDOP K, Billingsley JM, Yaffe Z, O'Connor G, et al
    Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication.
    PLoS Pathog. 2018;14:e1007246.
    PubMed     Text format     Abstract available


  6. OTSUKA Y, Schmitt K, Quinlan BD, Gardner MR, et al
    Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies.
    PLoS Pathog. 2018;14:e1007238.
    PubMed     Text format     Abstract available


  7. KMIEC D, Akbil B, Ananth S, Hotter D, et al
    SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.
    PLoS Pathog. 2018;14:e1007269.
    PubMed     Text format     Abstract available


    July 2018
  8. RAGHWANI J, Redd AD, Longosz AF, Wu CH, et al
    Evolution of HIV-1 within untreated individuals and at the population scale in Uganda.
    PLoS Pathog. 2018;14:e1007167.
    PubMed     Text format     Abstract available


  9. DZHIVHUHO GA, Rehrl SA, Ndlovu H, Horsnell WGC, et al
    Chronic schistosomiasis suppresses HIV-specific responses to DNA-MVA and MVA-gp140 Env vaccine regimens despite antihelminthic treatment and increases helminth-associated pathology in a mouse model.
    PLoS Pathog. 2018;14:e1007182.
    PubMed     Text format     Abstract available


  10. DINGENS AS, Acharya P, Haddox HK, Rawi R, et al
    Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
    PLoS Pathog. 2018;14:e1007159.
    PubMed     Text format     Abstract available


  11. MARSHALL VA, Labo N, Hao XP, Holdridge B, et al
    Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV.
    PLoS Pathog. 2018;14:e1007130.
    PubMed     Text format     Abstract available


    June 2018
  12. YACOOB C, Lange MD, Cohen K, Lathia K, et al
    B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques.
    PLoS Pathog. 2018;14:e1007120.
    PubMed     Text format     Abstract available


  13. SHIN YC, Bischof GF, Lauer WA, Gonzalez-Nieto L, et al
    A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products.
    PLoS Pathog. 2018;14:e1007143.
    PubMed     Text format     Abstract available


  14. WANAGURU M, Barry DJ, Benton DJ, O'Reilly NJ, et al
    Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis.
    PLoS Pathog. 2018;14:e1007117.
    PubMed     Text format     Abstract available


  15. ELLETT F, Pazhakh V, Pase L, Benard EL, et al
    Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo.
    PLoS Pathog. 2018;14:e1007063.
    PubMed     Text format     Abstract available


  16. GU CJ, Borjabad A, Hadas E, Kelschenbach J, et al
    EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment.
    PLoS Pathog. 2018;14:e1007061.
    PubMed     Text format     Abstract available


    May 2018
  17. RAM DR, Manickam C, Hueber B, Itell HL, et al
    Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques.
    PLoS Pathog. 2018;14:e1007104.
    PubMed     Text format     Abstract available


  18. XU M, Moresco JJ, Chang M, Mukim A, et al
    SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
    PLoS Pathog. 2018;14:e1007071.
    PubMed     Text format     Abstract available


  19. ROTEM E, Faingold O, Charni M, Klug YA, et al
    The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice.
    PLoS Pathog. 2018;14:e1007044.
    PubMed     Text format     Abstract available


  20. CROOKS ET, Grimley SL, Cully M, Osawa K, et al
    Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.
    PLoS Pathog. 2018;14:e1007024.
    PubMed     Text format     Abstract available


  21. SCHIFFNER T, Pallesen J, Russell RA, Dodd J, et al
    Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
    PLoS Pathog. 2018;14:e1006986.
    PubMed     Text format     Abstract available


    April 2018
  22. ENOSE-AKAHATA Y, Azodi S, Smith BR, Billioux BJ, et al
    Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases.
    PLoS Pathog. 2018;14:e1007042.
    PubMed     Text format     Abstract available


  23. LI Z, Mbonye U, Feng Z, Wang X, et al
    The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency.
    PLoS Pathog. 2018;14:e1007012.
    PubMed     Text format     Abstract available


  24. IKEDA T, Symeonides M, Albin JS, Li M, et al
    HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G.
    PLoS Pathog. 2018;14:e1007010.
    PubMed     Text format     Abstract available


  25. BARAJAS BC, Tanaka M, Robinson BA, Phuong DJ, et al
    Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging.
    PLoS Pathog. 2018;14:e1006977.
    PubMed     Text format     Abstract available


  26. WETZEL KS, Yi Y, Yadav A, Bauer AM, et al
    Loss of CXCR6 coreceptor usage characterizes pathogenic lentiviruses.
    PLoS Pathog. 2018;14:e1007003.
    PubMed     Text format     Abstract available


  27. BUGGERT M, Nguyen S, McLane LM, Steblyanko M, et al
    Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
    PLoS Pathog. 2018;14:e1006973.
    PubMed     Text format     Abstract available


  28. RICHARDSON SI, Chung AW, Natarajan H, Mabvakure B, et al
    HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.
    PLoS Pathog. 2018;14:e1006987.
    PubMed     Text format     Abstract available


  29. PETERSON CW, Wang J, Deleage C, Reddy S, et al
    Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.
    PLoS Pathog. 2018;14:e1006956.
    PubMed     Text format     Abstract available


  30. KUMAR A, Smith CEP, Giorgi EE, Eudailey J, et al
    Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.
    PLoS Pathog. 2018;14:e1006944.
    PubMed     Text format     Abstract available


    March 2018
  31. CONTRERAS X, Salifou K, Sanchez G, Helsmoortel M, et al
    Nuclear RNA surveillance complexes silence HIV-1 transcription.
    PLoS Pathog. 2018;14:e1006950.
    PubMed     Text format     Abstract available


  32. CHITRE AS, Kattah MG, Rosli YY, Pao M, et al
    A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function.
    PLoS Pathog. 2018;14:e1006806.
    PubMed     Text format     Abstract available


  33. WAGH K, Seaman MS, Zingg M, Fitzsimons T, et al
    Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.
    PLoS Pathog. 2018;14:e1006860.
    PubMed     Text format     Abstract available


  34. MEYERSON NR, Warren CJ, Vieira DASA, Diaz-Griferro F, et al
    Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes.
    PLoS Pathog. 2018;14:e1006906.
    PubMed     Text format     Abstract available


  35. ZHEN A, Peterson CW, Carrillo MA, Reddy SS, et al
    Correction: Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.
    PLoS Pathog. 2018;14:e1006891.
    PubMed     Text format     Abstract available


    February 2018
  36. AUCLAIR S, Liu F, Niu Q, Hou W, et al
    Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection.
    PLoS Pathog. 2018;14:e1006888.
    PubMed     Text format     Abstract available


  37. KLASSE PJ, Ketas TJ, Cottrell CA, Ozorowski G, et al
    Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
    PLoS Pathog. 2018;14:e1006913.
    PubMed     Text format     Abstract available


  38. FISHER BS, Green RR, Brown RR, Wood MP, et al
    Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
    PLoS Pathog. 2018;14:e1006871.
    PubMed     Text format     Abstract available


  39. KUHNERT D, Kouyos R, Shirreff G, Pecerska J, et al
    Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics.
    PLoS Pathog. 2018;14:e1006895.
    PubMed     Text format     Abstract available


  40. HASENKRUG KJ, Chougnet CA, Dittmer U
    Regulatory T cells in retroviral infections.
    PLoS Pathog. 2018;14:e1006776.
    PubMed     Text format     Abstract available


  41. WATSON DC, Moysi E, Valentin A, Bergamaschi C, et al
    Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.
    PLoS Pathog. 2018;14:e1006902.
    PubMed     Text format     Abstract available


  42. HOGAN LE, Vasquez J, Hobbs KS, Hanhauser E, et al
    Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30.
    PLoS Pathog. 2018;14:e1006856.
    PubMed     Text format     Abstract available


    January 2018
  43. TAKATA M, Soll SJ, Emery A, Blanco-Melo D, et al
    Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication.
    PLoS Pathog. 2018;14:e1006824.
    PubMed     Text format     Abstract available


  44. UPADHYAY C, Feyznezhad R, Yang W, Zhang H, et al
    Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations.
    PLoS Pathog. 2018;14:e1006812.
    PubMed     Text format     Abstract available


  45. REH L, Magnus C, Kadelka C, Kuhnert D, et al
    Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage.
    PLoS Pathog. 2018;14:e1006825.
    PubMed     Text format     Abstract available


  46. GALILEE M, Alian A
    The structure of FIV reverse transcriptase and its implications for non-nucleoside inhibitor resistance.
    PLoS Pathog. 2018;14:e1006849.
    PubMed     Text format     Abstract available


  47. TSO FY, Kossenkov AV, Lidenge SJ, Ngalamika O, et al
    RNA-Seq of Kaposi's sarcoma reveals alterations in glucose and lipid metabolism.
    PLoS Pathog. 2018;14:e1006844.
    PubMed     Text format     Abstract available


  48. ZHAO J, Cheng L, Wang H, Yu H, et al
    Infection and depletion of CD4+ group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway.
    PLoS Pathog. 2018;14:e1006819.
    PubMed     Text format     Abstract available


  49. BINNING JM, Smith AM, Hultquist JF, Craik CS, et al
    Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.
    PLoS Pathog. 2018;14:e1006830.
    PubMed     Text format     Abstract available


  50. KLEIN K, Nickel G, Nankya I, Kyeyune F, et al
    Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection.
    PLoS Pathog. 2018;14:e1006754.
    PubMed     Text format     Abstract available


  51. CLARRIDGE KE, Blazkova J, Einkauf K, Petrone M, et al
    Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals.
    PLoS Pathog. 2018;14:e1006792.
    PubMed     Text format     Abstract available


    December 2017
  52. GACH JS, Bouzin M, Wong MP, Chromikova V, et al
    Human Immunodeficiency Virus type-1 (HIV-1) evades antibody-dependent phagocytosis.
    PLoS Pathog. 2017;13:e1006793.
    PubMed     Text format     Abstract available


  53. DAVIS-GARDNER ME, Gardner MR, Alfant B, Farzan M, et al
    eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients.
    PLoS Pathog. 2017;13:e1006786.
    PubMed     Text format     Abstract available


  54. ZHEN A, Peterson CW, Carrillo MA, Reddy SS, et al
    Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.
    PLoS Pathog. 2017;13:e1006753.
    PubMed     Text format     Abstract available


  55. GAVEGNANO C, Brehm JH, Dupuy FP, Talla A, et al
    Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
    PLoS Pathog. 2017;13:e1006740.
    PubMed     Text format     Abstract available


  56. ZHANG Z, Gu Q, de Manuel Montero M, Bravo IG, et al
    Stably expressed APOBEC3H forms a barrier for cross-species transmission of simian immunodeficiency virus of chimpanzee to humans.
    PLoS Pathog. 2017;13:e1006746.
    PubMed     Text format     Abstract available


    November 2017
  57. MACKELPRANG RD, Bamshad MJ, Chong JX, Hou X, et al
    Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1.
    PLoS Pathog. 2017;13:e1006703.
    PubMed     Text format     Abstract available


  58. MCBRIDE JA, Striker R
    Imbalance in the game of T cells: What can the CD4/CD8 T-cell ratio tell us about HIV and health?
    PLoS Pathog. 2017;13:e1006624.
    PubMed     Text format    


    October 2017
  59. BAILEY AL, Buechler CR, Matson DR, Peterson EJ, et al
    Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection.
    PLoS Pathog. 2017;13:e1006692.
    PubMed     Text format     Abstract available


  60. ROGANOWICZ MD, Komurlu S, Mukherjee S, Plewka J, et al
    TRIM5alpha SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.
    PLoS Pathog. 2017;13:e1006686.
    PubMed     Text format     Abstract available


  61. PORTILLO JC, Muniz-Feliciano L, Lopez Corcino Y, Lee SJ, et al
    Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy.
    PLoS Pathog. 2017;13:e1006671.
    PubMed     Text format     Abstract available


  62. LEIBMAN RS, Richardson MW, Ellebrecht CT, Maldini CR, et al
    Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.
    PLoS Pathog. 2017;13:e1006613.
    PubMed     Text format     Abstract available


  63. RATO S, Rausell A, Munoz M, Telenti A, et al
    Single-cell analysis identifies cellular markers of the HIV permissive cell.
    PLoS Pathog. 2017;13:e1006678.
    PubMed     Text format     Abstract available


    September 2017
  64. OBENG-ADJEI N, Portugal S, Holla P, Li S, et al
    Malaria-induced interferon-gamma drives the expansion of Tbethi atypical memory B cells.
    PLoS Pathog. 2017;13:e1006576.
    PubMed     Text format     Abstract available


  65. DEL PRETE GQ, Keele BF, Fode J, Thumar K, et al
    A single gp120 residue can affect HIV-1 tropism in macaques.
    PLoS Pathog. 2017;13:e1006572.
    PubMed     Text format     Abstract available


  66. ABERE B, Mamo TM, Hartmann S, Samarina N, et al
    The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.
    PLoS Pathog. 2017;13:e1006639.
    PubMed     Text format     Abstract available


  67. ALLARD A, Althouse BM, Hebert-Dufresne L, Scarpino SV, et al
    The risk of sustained sexual transmission of Zika is underestimated.
    PLoS Pathog. 2017;13:e1006633.
    PubMed     Text format     Abstract available


  68. THOMAS AS, Jones KL, Gandhi RT, McMahon DK, et al
    mT-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.
    PLoS Pathog. 2017;13:e1006629.
    PubMed     Text format     Abstract available


  69. SEKI S, Nomura T, Nishizawa M, Yamamoto H, et al
    In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.
    PLoS Pathog. 2017;13:e1006638.
    PubMed     Text format     Abstract available


  70. SHRESTHA P, Davis DA, Veeranna RP, Carey RF, et al
    Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma.
    PLoS Pathog. 2017;13:e1006628.
    PubMed     Text format     Abstract available


  71. DUBROVSKAYA V, Guenaga J, de Val N, Wilson R, et al
    Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response.
    PLoS Pathog. 2017;13:e1006614.
    PubMed     Text format     Abstract available


  72. KIJAK GH, Sanders-Buell E, Chenine AL, Eller MA, et al
    Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
    PLoS Pathog. 2017;13:e1006620.
    PubMed     Text format     Abstract available



  73. Correction: CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.
    PLoS Pathog. 2017;13:e1006617.
    PubMed     Text format     Abstract available


  74. MARSDEN MD, Loy BA, Wu X, Ramirez CM, et al
    In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
    PLoS Pathog. 2017;13:e1006575.
    PubMed     Text format     Abstract available


  75. TARTOUR K, Nguyen XN, Appourchaux R, Assil S, et al
    Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.
    PLoS Pathog. 2017;13:e1006610.
    PubMed     Text format     Abstract available


  76. RADEMEYER C, Korber B, Seaman MS, Giorgi EE, et al
    Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.
    PLoS Pathog. 2017;13:e1006641.
    PubMed     Text format     Abstract available


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