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  HIV Infection

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Articles published in PLoS Pathog

Retrieve available abstracts of 89 articles:
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Single Articles


    September 2025
  1. DERBY N, Johnson BI, Biswas S, Fischer M, et al
    Liver biopsies obtained throughout SIV infection reveal evolving interferon stimulated protein expression within distinct monocyte/macrophage subsets.
    PLoS Pathog. 2025;21:e1013175.
    PubMed     Abstract available


  2. CHOSHI P, Pedretti S, Chimbetete T, Gangula R, et al
    The association of class II HLA alleles with tuberculosis-associated immune reconstitution inflammatory syndrome.
    PLoS Pathog. 2025;21:e1013497.
    PubMed     Abstract available


  3. PUERTAS MC, Bailon L, Urrea V, Garcia-Guerrero MC, et al
    Rapid clearance of inducible HIV-1 proviruses after initiation of antiretroviral therapy.
    PLoS Pathog. 2025;21:e1013466.
    PubMed     Abstract available


  4. RIVAULT A, Bernut A, Ben-Neji M, Abrantes M, et al
    HIV-1 Tat favors the multiplication of Mycobacterium tuberculosis and Toxoplasma by inhibiting clathrin-mediated endocytosis and autophagy.
    PLoS Pathog. 2025;21:e1013183.
    PubMed     Abstract available


  5. LEWIS CA, Margolis DM, Browne EP
    HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells.
    PLoS Pathog. 2025;21:e1013073.
    PubMed     Abstract available


  6. BUFFA DJ, O'Neil TR, Vine EE, Sarkawt L, et al
    Dendritic cells and HIV transmission: roles and subsets of antigen-presenting cells in the human anogenital tract.
    PLoS Pathog. 2025;21:e1013490.
    PubMed     Abstract available


  7. COLLERCANDY N, Vellas C, Nayrac M, Requena M, et al
    Cytotoxic CX3CR1+ Vdelta1 T cells clonally expand in an interplay of CMV, microbiota, and HIV-1 persistence in people on antiretroviral therapy.
    PLoS Pathog. 2025;21:e1013489.
    PubMed     Abstract available


    August 2025
  8. ZEEB M, Kusejko K, Hartnack S, Pasin C, et al
    Infection with Mycobacterium tuberculosis alters the antibody response to HIV-1.
    PLoS Pathog. 2025;21:e1013350.
    PubMed     Abstract available


  9. LI G, Ma J, Yu H, Tsahouridis O, et al
    CD24-Fc resolves inflammation and enhances anti-HIV CD8 T cells with polyfunctionality during HIV-1 infection under ART.
    PLoS Pathog. 2025;21:e1012826.
    PubMed     Abstract available


  10. SERWIN K, Mielczak K, Urbanska A, Aksak-Was B, et al
    Comparison of HIV-1 A6 dispersal dynamics in Poland before and after the war in Ukraine.
    PLoS Pathog. 2025;21:e1013369.
    PubMed     Abstract available


  11. TANG Y, Xie L, Shabangu CS, Li D, et al
    Persistent type I interferon signaling within the brain of people with HIV on ART with cognitive impairment.
    PLoS Pathog. 2025;21:e1013411.
    PubMed     Abstract available



  12. Retraction: Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
    PLoS Pathog. 2025;21:e1013442.
    PubMed    


    July 2025
  13. CHOUDHARY A, Mallick K, Dalavi R, Chande A, et al
    HIV-1 Vpr orchestrates ciTRAN upregulation through TGF-beta induction.
    PLoS Pathog. 2025;21:e1013332.
    PubMed     Abstract available


  14. RIST M, Kaku M, Coffin JM
    In vitro HIV DNA integration in STAT3 drives T cell persistence-A model of HIV-associated T cell lymphoma.
    PLoS Pathog. 2025;21:e1013087.
    PubMed     Abstract available


    June 2025
  15. NDLOVU B, Gounder K, Zikhali N, Singh L, et al
    Distinct neutralization sensitivity between adult and infant transmitted/founder HIV-1 subtype C viruses to broadly neutralizing monoclonal antibodies.
    PLoS Pathog. 2025;21:e1013245.
    PubMed     Abstract available


  16. MIYAKAWA K, Tanaka K, Ino Y, Kimura Y, et al
    PHD3-VHL axis controls HIV-2 infection through oxygen-dependent hydroxylation and degradation of Vpx.
    PLoS Pathog. 2025;21:e1013241.
    PubMed     Abstract available


  17. DESHPANDE A, Shi J, Rotem-Dai N, Aiken C, et al
    Reverse transcription progression and genome length regulate HIV-1 core elasticity and disassembly.
    PLoS Pathog. 2025;21:e1013269.
    PubMed     Abstract available


  18. SWITZER WM, Zheng H, Muniz CP, Pan Y, et al
    High prevalence of simian foamy virus infection of South American Indians.
    PLoS Pathog. 2025;21:e1013169.
    PubMed     Abstract available


  19. LAWRENCE LA, Williams ME, Vidal P, Varughese RS, et al
    Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge.
    PLoS Pathog. 2025;21:e1012276.
    PubMed     Abstract available


    May 2025
  20. AGRAWAL P, Khechaduri A, Salladay KR, MacCamy A, et al
    Increased immunogen valency improves the maturation of vaccine-elicited HIV-1 VRC01-like antibodies.
    PLoS Pathog. 2025;21:e1013039.
    PubMed     Abstract available


  21. ZHANG Y, Klein K, Ratcliff A, Galappaththi SL, et al
    Transmitted/founder (T/F) HIV-1 derived from sexual contact exhibits greater transmission fitness in human cervical tissue than T/F HIV-1 from blood-to-blood contact: Unique glycan profiles on T/F envelopes associated with transmission phenotypes.
    PLoS Pathog. 2025;21:e1013177.
    PubMed     Abstract available


  22. DZHIVHUHO GA, Jackson PEH, Honeycutt ES, Mesquita FDS, et al
    Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies.
    PLoS Pathog. 2025;21:e1012885.
    PubMed     Abstract available


    April 2025
  23. WOOTTUM M, Yan S, Durringer A, Meziere L, et al
    HIV-1 cell-to-cell infection of macrophages escapes type I interferon and host restriction factors, and is resistant to antiretroviral drugs.
    PLoS Pathog. 2025;21:e1013130.
    PubMed     Abstract available


  24. MARTIN MA, Brizzi A, Xi X, Galiwango RM, et al
    Quantifying prevalence and risk factors of HIV multiple infection in Uganda from population-based deep-sequence data.
    PLoS Pathog. 2025;21:e1013065.
    PubMed     Abstract available


  25. BUCHANAN LB, Shao Z, Galiwango RM, Constable S, et al
    HIV-associated penile anaerobes disrupt epithelial barrier integrity.
    PLoS Pathog. 2025;21:e1013094.
    PubMed     Abstract available


  26. FAIZO AAA, Bellward C, Hernandez-Lopez HR, Stevenson A, et al
    The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle.
    PLoS Pathog. 2025;21:e1012697.
    PubMed     Abstract available


  27. ASHOKKUMAR M, Hafer TL, Felton A, Archin NM, et al
    A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency.
    PLoS Pathog. 2025;21:e1012467.
    PubMed     Abstract available


  28. REEVES DB, Litchford M, Fish CS, Farrell-Sherman A, et al
    Intact HIV DNA decays in children with and without complete viral load suppression.
    PLoS Pathog. 2025;21:e1013003.
    PubMed     Abstract available


  29. ZHAO W, Modak A, Ross SR
    DHX15 inhibits mouse APOBEC3 deamination.
    PLoS Pathog. 2025;21:e1013045.
    PubMed     Abstract available


  30. SARKAR S, Kobayashi Y, Russnak T, Shen J, et al
    GS143, an inhibitor of E3 ligase beta-TrCP, reverses HIV-1 latency without activating T cells via unconventional activation of NFkappaB.
    PLoS Pathog. 2025;21:e1013018.
    PubMed     Abstract available


  31. NOORSAEED S, AlBurtamani N, Rokan A, Fassati A, et al
    Heat shock protein 90 is a chaperone regulator of HIV-1 latency.
    PLoS Pathog. 2025;21:e1012524.
    PubMed     Abstract available


    March 2025
  32. NAIR A, Davis DA, Warner A, Karim B, et al
    The elevated expression of ORF75, a KSHV lytic gene, in Kaposi sarcoma lesions is driven by a GC-rich DNA cis element in its promoter region.
    PLoS Pathog. 2025;21:e1012984.
    PubMed     Abstract available


  33. CANDOR K, Ding L, Balchand S, Hammonds JE, et al
    The CLIC/GEEC pathway regulates particle uptake and formation of the virus-containing compartment (VCC) in HIV-1-infected macrophages.
    PLoS Pathog. 2025;21:e1012564.
    PubMed     Abstract available


    February 2025
  34. IRRINKI AM, Kaur J, Randhawa B, McFadden R, et al
    Activating PKC-epsilon induces HIV expression with improved tolerability.
    PLoS Pathog. 2025;21:e1012874.
    PubMed     Abstract available


    January 2025
  35. GRIFFITH GL, Machmach K, Jian N, Kim D, et al
    CD16 and CD57 expressing gamma delta T cells in acute HIV-1 infection are associated with the development of neutralization breadth.
    PLoS Pathog. 2025;21:e1012916.
    PubMed     Abstract available


  36. SCOTT TM, Arnold LM, Powers JA, McCann DA, et al
    Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing.
    PLoS Pathog. 2025;21:e1012206.
    PubMed     Abstract available


  37. HUANG SW, Briganti L, Annamalai AS, Greenwood J, et al
    The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir.
    PLoS Pathog. 2025;21:e1012862.
    PubMed     Abstract available


  38. HUBAL A, Vendhoti A, Shaffer CN, Vos S, et al
    Inhibition of Src signaling induces autophagic killing of Toxoplasma gondii via PTEN-mediated deactivation of Akt.
    PLoS Pathog. 2025;21:e1012907.
    PubMed     Abstract available


  39. EDWARDS CT, Karunakaran KA, Garcia E, Beutler N, et al
    Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques.
    PLoS Pathog. 2025;21:e1012456.
    PubMed     Abstract available


  40. FOULKES C, Friedrich N, Ivan B, Stiegeler E, et al
    Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity.
    PLoS Pathog. 2025;21:e1012825.
    PubMed     Abstract available


  41. ROHLFES N, Radhakrishnan R, Singh PK, Bedwell GJ, et al
    The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection.
    PLoS Pathog. 2025;21:e1012354.
    PubMed     Abstract available


  42. FARINRE O, Anaya T, King AC, Endrias K, et al
    SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques.
    PLoS Pathog. 2025;21:e1012863.
    PubMed     Abstract available


  43. MAN S, Jansen J, Kroeze S, Geijtenbeek TBH, et al
    Transcriptomic HIV-1 reservoir profiling reveals a role for mitochondrial functionality in HIV-1 latency.
    PLoS Pathog. 2025;21:e1012822.
    PubMed     Abstract available


  44. HU K, O'Neil TR, Baharlou H, Austin PJ, et al
    The spatial biology of HIV infection.
    PLoS Pathog. 2025;21:e1012888.
    PubMed     Abstract available


    December 2024
  45. MAK NSC, Liu J, Zhang D, Taylor J, et al
    Alternative splicing expands the antiviral IFITM repertoire in Chinese rufous horseshoe bats.
    PLoS Pathog. 2024;20:e1012763.
    PubMed     Abstract available


  46. GROBBEN M, Bakker M, Schriek AI, Levels LJJ, et al
    Polyfunctionality and breadth of HIV-1 antibodies are associated with delayed disease progression.
    PLoS Pathog. 2024;20:e1012739.
    PubMed     Abstract available


  47. RADER AG, Cloherty APM, Patel KS, Almandawi DDA, et al
    HIV-1 exploits LBPA-dependent intraepithelial trafficking for productive infection of human intestinal mucosa.
    PLoS Pathog. 2024;20:e1012714.
    PubMed     Abstract available


  48. RICHEL E, Cordsmeier A, Bauer L, Fraedrich K, et al
    Mechanisms of sterilizing immunity provided by an HIV-1 neutralizing antibody against mucosal infection.
    PLoS Pathog. 2024;20:e1012777.
    PubMed     Abstract available


    November 2024
  49. FRANZEN BOGER M, Hasselrot T, Kaldhusdal V, Miranda GHB, et al
    Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection.
    PLoS Pathog. 2024;20:e1012709.
    PubMed     Abstract available


    October 2024
  50. SNOW BJ, Keles NK, Grunst MW, Janaka SK, et al
    Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells.
    PLoS Pathog. 2024;20:e1012665.
    PubMed     Abstract available


  51. JIANG P, Majerciak V, Hu J, Balogh K, et al
    The full transcription map of cottontail rabbit papillomavirus in tumor tissues.
    PLoS Pathog. 2024;20:e1012649.
    PubMed     Abstract available


  52. HOWARD JN, Levinger C, Deletsu S, Fromentin R, et al
    Isotretinoin promotes elimination of translation-competent HIV latent reservoirs in CD4T cells.
    PLoS Pathog. 2024;20:e1012601.
    PubMed     Abstract available


  53. BRINKKEMPER M, Kerster G, Brouwer PJM, Tran AS, et al
    Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes.
    PLoS Pathog. 2024;20:e1012558.
    PubMed     Abstract available


    September 2024
  54. DAS MK, Savidge B, Pearl JE, Yates T, et al
    Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis.
    PLoS Pathog. 2024;20:e1012565.
    PubMed     Abstract available


  55. HU Z, Cinque P, Dravid A, Hagberg L, et al
    Changes in cerebrospinal fluid proteins across the spectrum of untreated and treated chronic HIV-1 infection.
    PLoS Pathog. 2024;20:e1012470.
    PubMed     Abstract available


  56. CHEN YA, Vickers EN, Aranda-Diaz A, Murphy M, et al
    Genomic epidemiology demonstrates spatially clustered, local transmission of Plasmodium falciparum in forest-going populations in southern Lao PDR.
    PLoS Pathog. 2024;20:e1012194.
    PubMed     Abstract available


  57. PETRARA MR, Ruffoni E, Carmona F, Cavallari I, et al
    HIV reservoir and premature aging: risk factors for aging-associated illness in adolescents and young adults with perinatally acquired HIV.
    PLoS Pathog. 2024;20:e1012547.
    PubMed     Abstract available


  58. XU X, Niu M, Lamberty BG, Emanuel K, et al
    Microglia and macrophages alterations in the CNS during acute SIV infection: A single-cell analysis in rhesus macaques.
    PLoS Pathog. 2024;20:e1012168.
    PubMed     Abstract available


  59. CISNEROS WJ, Soliman SHA, Walter M, Simons LM, et al
    Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal.
    PLoS Pathog. 2024;20:e1012083.
    PubMed     Abstract available


  60. DESHPANDE A, Bryer AJ, Andino-Moncada JR, Shi J, et al
    Elasticity of the HIV-1 core facilitates nuclear entry and infection.
    PLoS Pathog. 2024;20:e1012537.
    PubMed     Abstract available


  61. ALTMAN PX, Ozorowski G, Stanfield RL, Haakenson J, et al
    Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
    PLoS Pathog. 2024;20:e1012042.
    PubMed     Abstract available


  62. JENNINGS J, Bracey H, Hong J, Nguyen DT, et al
    The HIV-1 capsid serves as a nanoscale reaction vessel for reverse transcription.
    PLoS Pathog. 2024;20:e1011810.
    PubMed     Abstract available


  63. ZHANG Y, Otte F, Stoeckle M, Thielen A, et al
    HIV-1 diversity in viral reservoirs obtained from circulating T-cell subsets during early ART and beyond.
    PLoS Pathog. 2024;20:e1012526.
    PubMed     Abstract available


  64. VUKOVICH MJ, Shiakolas AR, Lindenberger J, Richardson RA, et al
    Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families.
    PLoS Pathog. 2024;20:e1012499.
    PubMed     Abstract available


  65. SIMPSON J, Dulek B, Schaughency P, Brenchley JM, et al
    Multi-omics analysis of SIV-specific CD8+ T cells in multiple anatomical sites.
    PLoS Pathog. 2024;20:e1012545.
    PubMed     Abstract available


    August 2024
  66. VARCO-MERTH B, Chaunzwa M, Duell DM, Marenco A, et al
    Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence.
    PLoS Pathog. 2024;20:e1012496.
    PubMed     Abstract available


  67. ZHOU Z, Guo J, Hetrick B, Tiwari S, et al
    Characterization of a CXCR4 antagonist TIQ-15 with dual tropic HIV entry inhibition properties.
    PLoS Pathog. 2024;20:e1012448.
    PubMed     Abstract available


  68. VAN DER STRATEN K, Guerra D, Kerster G, Claireaux M, et al
    Primary SARS-CoV-2 variant of concern infections elicit broad antibody Fc-mediated effector functions and memory B cell responses.
    PLoS Pathog. 2024;20:e1012453.
    PubMed     Abstract available


  69. NEUNER-JEHLE N, Zeeb M, Thorball CW, Fellay J, et al
    Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen.
    PLoS Pathog. 2024;20:e1012385.
    PubMed     Abstract available


  70. JAMAL EDDINE J, Angelovich TA, Zhou J, Byrnes SJ, et al
    HIV transcription persists in the brain of virally suppressed people with HIV.
    PLoS Pathog. 2024;20:e1012446.
    PubMed     Abstract available


  71. XU S, Li H, Ai Z, Guo R, et al
    Exploring viral neuropathic pain: Molecular mechanisms and therapeutic implications.
    PLoS Pathog. 2024;20:e1012397.
    PubMed     Abstract available


    July 2024
  72. PHAN T, Conway JM, Pagane N, Kreig J, et al
    Understanding early HIV-1 rebound dynamics following antiretroviral therapy interruption: The importance of effector cell expansion.
    PLoS Pathog. 2024;20:e1012236.
    PubMed     Abstract available


  73. UMTHONG S, Timilsina U, D'Angelo MR, Salka K, et al
    MARCH2, a T cell specific factor that restricts HIV-1 infection.
    PLoS Pathog. 2024;20:e1012330.
    PubMed     Abstract available


  74. MARSHALL VA, Cornejo Castro EM, Goodman CA, Labo N, et al
    Sequencing of Kaposi's Sarcoma Herpesvirus (KSHV) genomes from persons of diverse ethnicities and provenances with KSHV-associated diseases demonstrate multiple infections, novel polymorphisms, and low intra-host variance.
    PLoS Pathog. 2024;20:e1012338.
    PubMed     Abstract available


  75. AL-KAABI M, Deshpande P, Firth M, Pavlos R, et al
    Epistatic interaction between ERAP2 and HLA modulates HIV-1 adaptation and disease outcome in an Australian population.
    PLoS Pathog. 2024;20:e1012359.
    PubMed     Abstract available


    June 2024
  76. WARNER VAN DIJK FA, Tong O, O'Neil TR, Bertram KM, et al
    Characterising plasmacytoid and myeloid AXL+ SIGLEC-6+ dendritic cell functions and their interactions with HIV.
    PLoS Pathog. 2024;20:e1012351.
    PubMed     Abstract available


  77. BUSSEY-SUTTON CR, Ward A, Fox JA, Turner AW, et al
    The histone methyltransferase SETD2 regulates HIV expression and latency.
    PLoS Pathog. 2024;20:e1012281.
    PubMed     Abstract available


    May 2024
  78. KARSTEN CB, Buettner FFR, Cajic S, Nehlmeier I, et al
    Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivity.
    PLoS Pathog. 2024;20:e1012190.
    PubMed     Abstract available


  79. AMORIM SACRAMENTO L, Farias Amorim C, G Lombana C, Beiting D, et al
    CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions.
    PLoS Pathog. 2024;20:e1012211.
    PubMed     Abstract available


  80. WINDELS EM, Wampande EM, Joloba ML, Boom WH, et al
    HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa.
    PLoS Pathog. 2024;20:e1011675.
    PubMed     Abstract available


  81. WILHELM E, Poirier M, Da Rocha M, Bedard M, et al
    Mitotic deacetylase complex (MiDAC) recognizes the HIV-1 core promoter to control activated viral gene expression.
    PLoS Pathog. 2024;20:e1011821.
    PubMed     Abstract available


  82. MANICKAM C, Upadhyay AA, Woolley G, Kroll KW, et al
    Natural killer-like B cells are a distinct but infrequent innate immune cell subset modulated by SIV infection of rhesus macaques.
    PLoS Pathog. 2024;20:e1012223.
    PubMed     Abstract available


    April 2024
  83. KUZMINA A, Sadhu L, Hasanuzzaman M, Fujinaga K, et al
    Direct and indirect effects of CYTOR lncRNA regulate HIV gene expression.
    PLoS Pathog. 2024;20:e1012172.
    PubMed     Abstract available


  84. KEELE BF, Okoye AA, Fennessey CM, Varco-Merth B, et al
    Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir.
    PLoS Pathog. 2024;20:e1012135.
    PubMed     Abstract available


  85. WONG RW, Balachandran A, Cheung PK, Cheng R, et al
    Correction: An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing.
    PLoS Pathog. 2024;20:e1012155.
    PubMed     Abstract available


    March 2024
  86. LAYISH B, Goli R, Flick H, Huang SW, et al
    Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions.
    PLoS Pathog. 2024;20:e1011830.
    PubMed     Abstract available


  87. ZHANG X, Hu Y, Vandenhoudt RE, Yan C, et al
    Computationally inferred cell-type specific epigenome-wide DNA methylation analysis unveils distinct methylation patterns among immune cells for HIV infection in three cohorts.
    PLoS Pathog. 2024;20:e1012063.
    PubMed     Abstract available


    February 2024
  88. JOSEPH SB, Abrahams MR, Moeser M, Tyers L, et al
    The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus.
    PLoS Pathog. 2024;20:e1011974.
    PubMed     Abstract available


  89. BENNETT SJ, Yalcin D, Privatt SR, Ngalamika O, et al
    Antibody profiling and predictive modeling discriminate between Kaposi sarcoma and asymptomatic KSHV infection.
    PLoS Pathog. 2024;20:e1012023.
    PubMed     Abstract available


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