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Articles published in PLoS Pathog

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Single Articles


    September 2022
  1. GARCIA-KNIGHT M, Anglin K, Tassetto M, Lu S, et al
    Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study.
    PLoS Pathog. 2022;18:e1010802.
    PubMed     Abstract available


  2. WHITE JA, Kufera JT, Bachmann N, Dai W, et al
    Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods.
    PLoS Pathog. 2022;18:e1010845.
    PubMed     Abstract available


  3. KARSTEN CB, Bartsch YC, Shin SA, Slein MD, et al
    Evolution of functional antibodies following acute Epstein-Barr virus infection.
    PLoS Pathog. 2022;18:e1010738.
    PubMed     Abstract available


  4. SCHEEPERS C, Kgagudi P, Mzindle N, Gray ES, et al
    Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies.
    PLoS Pathog. 2022;18:e1010450.
    PubMed     Abstract available


    August 2022
  5. MORRIS SE, Strehlau R, Shiau S, Abrams EJ, et al
    Healthy dynamics of CD4 T cells may drive HIV resurgence in perinatally-infected infants on antiretroviral therapy.
    PLoS Pathog. 2022;18:e1010751.
    PubMed     Abstract available


  6. FRANCIS AC, Cereseto A, Singh PK, Shi J, et al
    Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles.
    PLoS Pathog. 2022;18:e1010754.
    PubMed     Abstract available


  7. JUNG KL, Choi UY, Park A, Foo SS, et al
    Single-cell analysis of Kaposi's sarcoma-associated herpesvirus infection in three-dimensional air-liquid interface culture model.
    PLoS Pathog. 2022;18:e1010775.
    PubMed     Abstract available


  8. GUO S, Luke BT, Henry AR, Darko S, et al
    HIV infected CD4+ T cell clones are more stable than uninfected clones during long-term antiretroviral therapy.
    PLoS Pathog. 2022;18:e1010726.
    PubMed     Abstract available


    July 2022
  9. STRONGIN Z, Hoang TN, Tharp GK, Rahmberg AR, et al
    The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence.
    PLoS Pathog. 2022;18:e1010723.
    PubMed     Abstract available


  10. MAJERCIAK V, Alvarado-Hernandez B, Lobanov A, Cam M, et al
    Genome-wide regulation of KSHV RNA splicing by viral RNA-binding protein ORF57.
    PLoS Pathog. 2022;18:e1010311.
    PubMed     Abstract available


  11. YE F, Alvarez-Carbonell D, Nguyen K, Leskov K, et al
    Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells.
    PLoS Pathog. 2022;18:e1010110.
    PubMed     Abstract available


  12. MUNOZ O, Banga R, Schelling R, Procopio FA, et al
    Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells.
    PLoS Pathog. 2022;18:e1010673.
    PubMed     Abstract available


  13. SIMPSON J, Starke CE, Ortiz AM, Ransier A, et al
    Multiple modes of antigen exposure induce clonotypically diverse epitope-specific CD8+ T cells across multiple tissues in nonhuman primates.
    PLoS Pathog. 2022;18:e1010611.
    PubMed     Abstract available


    June 2022
  14. LAWRENCE SP, Elser SE, Torben W, Blair RV, et al
    A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection.
    PLoS Pathog. 2022;18:e1010507.
    PubMed     Abstract available


  15. WELLES HC, King HAD, Nettey L, Cavett N, et al
    Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4.
    PLoS Pathog. 2022;18:e1010574.
    PubMed     Abstract available


  16. LINDQVIST B, Jutte BB, Love L, Assi W, et al
    T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin.
    PLoS Pathog. 2022;18:e1010555.
    PubMed     Abstract available


  17. FILES DC, Tacke F, O'Sullivan A, Dorr P, et al
    Rationale of using the dual chemokine receptor CCR2/CCR5 inhibitor cenicriviroc for the treatment of COVID-19.
    PLoS Pathog. 2022;18:e1010547.
    PubMed     Abstract available


  18. FITTJE P, Hoelzemer A, Garcia-Beltran WF, Vollmers S, et al
    HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells.
    PLoS Pathog. 2022;18:e1010572.
    PubMed     Abstract available


    May 2022
  19. HAN M, Cantaloube-Ferrieu V, Xie M, Armani-Tourret M, et al
    HIV-1 cell-to-cell spread overcomes the virus entry block of non-macrophage-tropic strains in macrophages.
    PLoS Pathog. 2022;18:e1010335.
    PubMed     Abstract available


  20. SCHAPIRO HM, Khasnis MD, Ahn K, Karagiaridi A, et al
    Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env.
    PLoS Pathog. 2022;18:e1010531.
    PubMed     Abstract available


  21. BRADLEY F, Franzen Boger M, Kaldhusdal V, Ahlberg A, et al
    Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate.
    PLoS Pathog. 2022;18:e1010494.
    PubMed     Abstract available


  22. WELBOURN S, Chakraborty S, Yang JE, Gleinich AS, et al
    A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence.
    PLoS Pathog. 2022;18:e1010488.
    PubMed     Abstract available


    April 2022
  23. HINGANKAR N, Deshpande S, Das P, Rizvi ZA, et al
    A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 Delta variant.
    PLoS Pathog. 2022;18:e1010465.
    PubMed     Abstract available


  24. MOLDT B, Chandrashekar A, Borducchi EN, Nkolola JP, et al
    HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys.
    PLoS Pathog. 2022;18:e1010467.
    PubMed     Abstract available


    March 2022
  25. JURCZYSZAK D, Manganaro L, Buta S, Gruber C, et al
    ISG15 deficiency restricts HIV-1 infection.
    PLoS Pathog. 2022;18:e1010405.
    PubMed     Abstract available


  26. LEWITUS E, Townsley SM, Li Y, Donofrio GC, et al
    HIV-1 infections with multiple founders associate with the development of neutralization breadth.
    PLoS Pathog. 2022;18:e1010369.
    PubMed     Abstract available


  27. BARBIAN HJ, Seaton MS, Narasipura SD, Wallace J, et al
    beta-catenin regulates HIV latency and modulates HIV reactivation.
    PLoS Pathog. 2022;18:e1010354.
    PubMed     Abstract available


  28. JAMES A, Dixit NM
    Transmitted HIV-1 is more virulent in heterosexual individuals than men-who-have-sex-with-men.
    PLoS Pathog. 2022;18:e1010319.
    PubMed     Abstract available


  29. ORTEGA-GONZALEZ P, Taylor G, Jangra RK, Tenorio R, et al
    Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis.
    PLoS Pathog. 2022;18:e1010322.
    PubMed     Abstract available


  30. SHAHBAZ S, Okoye I, Blevins G, Elahi S, et al
    Elevated ATP via enhanced miRNA-30b, 30c, and 30e downregulates the expression of CD73 in CD8+ T cells of HIV-infected individuals.
    PLoS Pathog. 2022;18:e1010378.
    PubMed     Abstract available


  31. CHANG XL, Reed JS, Webb GM, Wu HL, et al
    Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species.
    PLoS Pathog. 2022;18:e1010396.
    PubMed     Abstract available


    February 2022
  32. XUE G, Braczyk K, Goncalves-Carneiro D, Dawidziak DM, et al
    Poly(ADP-ribose) potentiates ZAP antiviral activity.
    PLoS Pathog. 2022;18:e1009202.
    PubMed     Abstract available


  33. PAMPUSCH MS, Abdelaal HM, Cartwright EK, Molden JS, et al
    CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection.
    PLoS Pathog. 2022;18:e1009831.
    PubMed     Abstract available


  34. STROEHLEIN AJ, Korhonen PK, Lee VV, Ralph SA, et al
    Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation.
    PLoS Pathog. 2022;18:e1010288.
    PubMed     Abstract available


    January 2022
  35. OKOYE AA, Fromentin R, Takata H, Brehm JH, et al
    The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription.
    PLoS Pathog. 2022;18:e1010245.
    PubMed     Abstract available


  36. GRAU-EXPOSITO J, Perea D, Suppi M, Massana N, et al
    Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells.
    PLoS Pathog. 2022;18:e1010171.
    PubMed     Abstract available


  37. HIOE CE, Li G, Liu X, Tsahouridis O, et al
    Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice.
    PLoS Pathog. 2022;18:e1010183.
    PubMed     Abstract available


  38. MOHAMMADI A, Bagherichimeh S, Choi Y, Fazel A, et al
    Insertive condom-protected and condomless vaginal sex both have a profound impact on the penile immune correlates of HIV susceptibility.
    PLoS Pathog. 2022;18:e1009948.
    PubMed     Abstract available


  39. DASKOU M, Mu W, Sharma M, Vasilopoulos H, et al
    ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV.
    PLoS Pathog. 2022;18:e1010160.
    PubMed     Abstract available


  40. ZHUKOVA A, Voznica J, Felipe MD, To TH, et al
    Correction: Cuban history of CRF19 recombinant subtype of HIV-1.
    PLoS Pathog. 2022;18:e1010224.
    PubMed     Abstract available


    December 2021
  41. KUNIHOLM J, Armstrong E, Bernabe B, Coote C, et al
    Intragenic proviral elements support transcription of defective HIV-1 proviruses.
    PLoS Pathog. 2021;17:e1009982.
    PubMed     Abstract available


  42. MELTON A, Doyle-Meyers LA, Blair RV, Midkiff C, et al
    The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease.
    PLoS Pathog. 2021;17:e1010162.
    PubMed     Abstract available


  43. MURRAY JM
    Dynamics of latent HIV under clonal expansion.
    PLoS Pathog. 2021;17:e1010165.
    PubMed     Abstract available


  44. SHARMA V, Creegan M, Tokarev A, Hsu D, et al
    Cerebrospinal fluid CD4+ T cell infection in humans and macaques during acute HIV-1 and SHIV infection.
    PLoS Pathog. 2021;17:e1010105.
    PubMed     Abstract available


  45. RIVERA-CUEVAS Y, Mayoral J, Di Cristina M, Lawrence AE, et al
    Toxoplasma gondii exploits the host ESCRT machinery for parasite uptake of host cytosolic proteins.
    PLoS Pathog. 2021;17:e1010138.
    PubMed     Abstract available


  46. OLBRICH L, Stockdale L, Basu Roy R, Song R, et al
    Understanding the interaction between cytomegalovirus and tuberculosis in children: The way forward.
    PLoS Pathog. 2021;17:e1010061.
    PubMed     Abstract available


  47. ZILA V, Muller TG, Muller B, Krausslich HG, et al
    HIV-1 capsid is the key orchestrator of early viral replication.
    PLoS Pathog. 2021;17:e1010109.
    PubMed    


    November 2021
  48. FISCHINGER S, Cizmeci D, Deng D, Grant SP, et al
    Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials.
    PLoS Pathog. 2021;17:e1010016.
    PubMed     Abstract available


  49. STONEHAM CA, Langer S, De Jesus PD, Wozniak JM, et al
    A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.
    PLoS Pathog. 2021;17:e1009409.
    PubMed     Abstract available


  50. TAYLOR RA, McRaven MD, Carias AM, Anderson MR, et al
    Localization of infection in neonatal rhesus macaques after oral viral challenge.
    PLoS Pathog. 2021;17:e1009855.
    PubMed     Abstract available


  51. ADRIANO VIEIRA V, Adland E, Malone DFG, Martin MP, et al
    An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults.
    PLoS Pathog. 2021;17:e1010090.
    PubMed     Abstract available


  52. ZHAO Z, Fagerlund R, Tossavainen H, Hopfensperger K, et al
    Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage.
    PLoS Pathog. 2021;17:e1009728.
    PubMed     Abstract available


  53. MIELKE D, Bandawe G, Zheng J, Jones J, et al
    ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection.
    PLoS Pathog. 2021;17:e1010046.
    PubMed     Abstract available


  54. ADENIJI OS, Kuri-Cervantes L, Yu C, Xu Z, et al
    Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells.
    PLoS Pathog. 2021;17:e1010034.
    PubMed     Abstract available


    October 2021
  55. MARTIN MM, Matkovic R, Larrous P, Morel M, et al
    Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx.
    PLoS Pathog. 2021;17:e1009609.
    PubMed     Abstract available


  56. KMIEC D, Lista MJ, Ficarelli M, Swanson CM, et al
    S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies.
    PLoS Pathog. 2021;17:e1009726.
    PubMed     Abstract available


  57. CROOKS ET, Almanza F, D'Addabbo A, Duggan E, et al
    Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens.
    PLoS Pathog. 2021;17:e1009807.
    PubMed     Abstract available


  58. NGUYEN K, Dobrowolski C, Shukla M, Cho WK, et al
    Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation.
    PLoS Pathog. 2021;17:e1010014.
    PubMed     Abstract available


    September 2021
  59. MISHRA N, Kumar S, Singh S, Bansal T, et al
    Cross-neutralization of SARS-CoV-2 by HIV-1 specific broadly neutralizing antibodies and polyclonal plasma.
    PLoS Pathog. 2021;17:e1009958.
    PubMed     Abstract available


  60. ALJEDANI SS, Liban TJ, Tran K, Phad G, et al
    Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
    PLoS Pathog. 2021;17:e1009543.
    PubMed     Abstract available


  61. LUSTIG G, Cele S, Karim F, Derache A, et al
    T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy.
    PLoS Pathog. 2021;17:e1009871.
    PubMed     Abstract available


  62. GUEDAN A, Donaldson CD, Caroe ER, Cosnefroy O, et al
    HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration.
    PLoS Pathog. 2021;17:e1009484.
    PubMed     Abstract available


  63. MBONYE U, Leskov K, Shukla M, Valadkhan S, et al
    Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways.
    PLoS Pathog. 2021;17:e1009581.
    PubMed     Abstract available


    August 2021
  64. VAN SCHOOTEN J, van Haaren MM, Li H, McCoy LE, et al
    Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.
    PLoS Pathog. 2021;17:e1009736.
    PubMed     Abstract available


  65. JOHNSON EL, Swieboda D, Olivier A, Enninga EAL, et al
    Robust innate immune responses at the placenta during early gestation may limit in utero HIV transmission.
    PLoS Pathog. 2021;17:e1009860.
    PubMed     Abstract available


  66. KOYUNCU D, Niazi MKK, Tavolara T, Abeijon C, et al
    CXCL1: A new diagnostic biomarker for human tuberculosis discovered using Diversity Outbred mice.
    PLoS Pathog. 2021;17:e1009773.
    PubMed     Abstract available


  67. CORLEY MJ, Sacdalan C, Pang AP, Chomchey N, et al
    Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART.
    PLoS Pathog. 2021;17:e1009785.
    PubMed     Abstract available


  68. ZHUKOVA A, Voznica J, Davila Felipe M, To TH, et al
    Cuban history of CRF19 recombinant subtype of HIV-1.
    PLoS Pathog. 2021;17:e1009786.
    PubMed     Abstract available


  69. YU L, Majerciak V, Xue XY, Uberoi A, et al
    Mouse papillomavirus type 1 (MmuPV1) DNA is frequently integrated in benign tumors by microhomology-mediated end-joining.
    PLoS Pathog. 2021;17:e1009812.
    PubMed     Abstract available


  70. PINO M, Pereira Ribeiro S, Pagliuzza A, Ghneim K, et al
    Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART.
    PLoS Pathog. 2021;17:e1009825.
    PubMed     Abstract available


  71. BANCHENKO S, Krupp F, Gotthold C, Burger J, et al
    Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.
    PLoS Pathog. 2021;17:e1009775.
    PubMed     Abstract available


    July 2021
  72. KERVEVAN J, Bouteau A, Lanza JS, Hammoudi A, et al
    Targeting human langerin promotes HIV-1 specific humoral immune responses.
    PLoS Pathog. 2021;17:e1009749.
    PubMed     Abstract available


  73. BISWAS A, Zhou D, Fiches GN, Wu Z, et al
    Inhibition of polo-like kinase 1 (PLK1) facilitates reactivation of gamma-herpesviruses and their elimination.
    PLoS Pathog. 2021;17:e1009764.
    PubMed     Abstract available


  74. WEN J, Cheever T, Wang L, Wu D, et al
    Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques.
    PLoS Pathog. 2021;17:e1009738.
    PubMed     Abstract available


  75. BARRENAS F, Hansen SG, Law L, Driscoll C, et al
    Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy.
    PLoS Pathog. 2021;17:e1009278.
    PubMed     Abstract available


  76. MAEHIGASHI T, Ahn S, Kim UI, Lindenberger J, et al
    A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.
    PLoS Pathog. 2021;17:e1009671.
    PubMed     Abstract available


  77. CHAKHTOURA M, Fang M, Cubas R, O'Connor MH, et al
    Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling.
    PLoS Pathog. 2021;17:e1009732.
    PubMed     Abstract available


    June 2021
  78. LEE MY, Upadhyay AA, Walum H, Chan CN, et al
    Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.
    PLoS Pathog. 2021;17:e1009674.
    PubMed     Abstract available


  79. MCDONNELL MM, Karvonen SC, Gaba A, Flath B, et al
    Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms.
    PLoS Pathog. 2021;17:e1009523.
    PubMed     Abstract available


  80. IMMONEN TT, Fennessey CM, Lipkey L, Thorpe A, et al
    Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir.
    PLoS Pathog. 2021;17:e1009686.
    PubMed     Abstract available


  81. CAI F, Chen WH, Wu W, Jones JA, et al
    Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
    PLoS Pathog. 2021;17:e1009624.
    PubMed     Abstract available


  82. TAYLOR RA, Xiao S, Carias AM, McRaven MD, et al
    PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure.
    PLoS Pathog. 2021;17:e1009632.
    PubMed     Abstract available


  83. WONG YC, Liu W, Yim LY, Li X, et al
    Sustained viremia suppression by SHIVSF162P3CN-recalled effector-memory CD8+ T cells after PD1-based vaccination.
    PLoS Pathog. 2021;17:e1009647.
    PubMed     Abstract available


    May 2021
  84. BULLINGTON BW, Klemperer K, Mages K, Chalem A, et al
    Effects of schistosomes on host anti-viral immune response and the acquisition, virulence, and prevention of viral infections: A systematic review.
    PLoS Pathog. 2021;17:e1009555.
    PubMed     Abstract available


  85. WOOD MP, Jones CI, Lippy A, Oliver BG, et al
    Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques.
    PLoS Pathog. 2021;17:e1009575.
    PubMed     Abstract available


  86. COOMER CA, Carlon-Andres I, Iliopoulou M, Dustin ML, et al
    Correction: Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion.
    PLoS Pathog. 2021;17:e1009584.
    PubMed     Abstract available


  87. BOCHART RM, Busman-Sahay K, Bondoc S, Morrow DW, et al
    Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques.
    PLoS Pathog. 2021;17:e1009565.
    PubMed     Abstract available


    April 2021
  88. SHAPIRO M, Krug LT, MacCarthy T
    Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection.
    PLoS Pathog. 2021;17:e1009560.
    PubMed     Abstract available


  89. BERTRAM KM, Truong NR, Smith JB, Kim M, et al
    Herpes Simplex Virus type 1 infects Langerhans cells and the novel epidermal dendritic cell, Epi-cDC2s, via different entry pathways.
    PLoS Pathog. 2021;17:e1009536.
    PubMed     Abstract available


  90. RINALDI S, de Armas L, Dominguez-Rodriguez S, Pallikkuth S, et al
    T cell immune discriminants of HIV reservoir size in a pediatric cohort of perinatally infected individuals.
    PLoS Pathog. 2021;17:e1009533.
    PubMed     Abstract available


  91. GONCALVES-CARNEIRO D, Takata MA, Ong H, Shilton A, et al
    Origin and evolution of the zinc finger antiviral protein.
    PLoS Pathog. 2021;17:e1009545.
    PubMed     Abstract available


  92. TONG O, Duette G, O'Neil TR, Royle CM, et al
    Plasmacytoid dendritic cells have divergent effects on HIV infection of initial target cells and induce a pro-retention phenotype.
    PLoS Pathog. 2021;17:e1009522.
    PubMed     Abstract available


  93. ARMANI-TOURRET M, Zhou Z, Gasser R, Staropoli I, et al
    Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis.
    PLoS Pathog. 2021;17:e1009526.
    PubMed     Abstract available


  94. TRIANTAFILOU K, Ward CJK, Czubala M, Ferris RG, et al
    Differential recognition of HIV-stimulated IL-1beta and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages.
    PLoS Pathog. 2021;17:e1009417.
    PubMed     Abstract available


  95. KUMAR R, Deshpande S, Sewall LM, Ozorowski G, et al
    Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer.
    PLoS Pathog. 2021;17:e1008977.
    PubMed     Abstract available


  96. COFFIN JM, Bale MJ, Wells D, Guo S, et al
    Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy.
    PLoS Pathog. 2021;17:e1009141.
    PubMed     Abstract available


  97. KUMAR A, Giorgi EE, Tu JJ, Martinez DR, et al
    Mutations that confer resistance to broadly-neutralizing antibodies define HIV-1 variants of transmitting mothers from that of non-transmitting mothers.
    PLoS Pathog. 2021;17:e1009478.
    PubMed     Abstract available


  98. ZHEN A, Carrillo MA, Mu W, Rezek V, et al
    Robust CAR-T memory formation and function via hematopoietic stem cell delivery.
    PLoS Pathog. 2021;17:e1009404.
    PubMed     Abstract available


    March 2021
  99. LUCENA LAGE S, Wong CS, Pinheiro Amaral E, Sturdevant D, et al
    Classical complement and inflammasome activation converge in CD14highCD16- monocytes in HIV associated TB-immune reconstitution inflammatory syndrome.
    PLoS Pathog. 2021;17:e1009435.
    PubMed     Abstract available


  100. LEE CD, Watanabe Y, Wu NC, Han J, et al
    A cross-neutralizing antibody between HIV-1 and influenza virus.
    PLoS Pathog. 2021;17:e1009407.
    PubMed     Abstract available


  101. CHEN S, Kumar S, Espada CE, Tirumuru N, et al
    N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages.
    PLoS Pathog. 2021;17:e1009421.
    PubMed     Abstract available


  102. SOWD GA, Aiken C
    Correction: Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells.
    PLoS Pathog. 2021;17:e1009389.
    PubMed     Abstract available


  103. MDLULI T, Jian N, Slike B, Paquin-Proulx D, et al
    Correction: RV144 HIV-1 vaccination impacts post-infection antibody responses.
    PLoS Pathog. 2021;17:e1009386.
    PubMed     Abstract available


  104. ANDERSEN-NISSEN E, Fiore-Gartland A, Ballweber Fleming L, Carpp LN, et al
    Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk.
    PLoS Pathog. 2021;17:e1009363.
    PubMed     Abstract available


  105. ROLLAND M, Gilbert PB
    Sieve analysis to understand how SARS-CoV-2 diversity can impact vaccine protection.
    PLoS Pathog. 2021;17:e1009406.
    PubMed    


    February 2021
  106. JEFFERYS SR, Burgos SD, Peterson JJ, Selitsky SR, et al
    Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors.
    PLoS Pathog. 2021;17:e1009346.
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  107. BRUCE JW, Bracken M, Evans E, Sherer N, et al
    ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses.
    PLoS Pathog. 2021;17:e1009364.
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  108. HSU DC, Schuetz A, Imerbsin R, Silsorn D, et al
    TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption.
    PLoS Pathog. 2021;17:e1009339.
    PubMed     Abstract available


  109. GAO Y, He S, Tian W, Li D, et al
    First complete-genome documentation of HIV-1 intersubtype superinfection with transmissions of diverse recombinants over time to five recipients.
    PLoS Pathog. 2021;17:e1009258.
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  110. CHARLES TP, Burton SL, Arunachalam PS, Cottrell CA, et al
    The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.
    PLoS Pathog. 2021;17:e1009257.
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  111. RENNER N, Mallery DL, Faysal KMR, Peng W, et al
    A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly.
    PLoS Pathog. 2021;17:e1009164.
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  112. DINKELE R, Gessner S, McKerry A, Leonard B, et al
    Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols.
    PLoS Pathog. 2021;17:e1009262.
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    January 2021
  113. SOWD GA, Aiken C
    Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells.
    PLoS Pathog. 2021;17:e1009190.
    PubMed     Abstract available


  114. BACCHUS-SOUFFAN C, Fitch M, Symons J, Abdel-Mohsen M, et al
    Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.
    PLoS Pathog. 2021;17:e1009214.
    PubMed     Abstract available


  115. CARLIN E, Greer B, Lowman K, Duverger A, et al
    Extensive proteomic and transcriptomic changes quench the TCR/CD3 activation signal of latently HIV-1 infected T cells.
    PLoS Pathog. 2021;17:e1008748.
    PubMed     Abstract available


  116. SANTIAGO JC, Goldman JD, Zhao H, Pankow AP, et al
    Intra-host changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma.
    PLoS Pathog. 2021;17:e1008594.
    PubMed     Abstract available


  117. SHRESTHA P, Davis DA, Jaeger HK, Stream A, et al
    Pomalidomide restores immune recognition of primary effusion lymphoma through upregulation of ICAM-1 and B7-2.
    PLoS Pathog. 2021;17:e1009091.
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    December 2020
  118. AKAHOSHI T, Gatanaga H, Kuse N, Chikata T, et al
    T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics.
    PLoS Pathog. 2020;16:e1009177.
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  119. UPADHYAY C, Feyznezhad R, Cao L, Chan KW, et al
    Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes.
    PLoS Pathog. 2020;16:e1009185.
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  120. NOEL-ROMAS L, Perner M, Molatlhegi R, Farr Zuend C, et al
    Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition.
    PLoS Pathog. 2020;16:e1009097.
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  121. WINANS S, Goff SP
    Mutations altering acetylated residues in the CTD of HIV-1 integrase cause defects in proviral transcription at early times after integration of viral DNA.
    PLoS Pathog. 2020;16:e1009147.
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  122. KHAMASSI M, Xu L, Rey J, Duchemin M, et al
    The CH1alpha domain of mucosal gp41 IgA contributes to antibody specificity and antiviral functions in HIV-1 highly exposed Sero-Negative individuals.
    PLoS Pathog. 2020;16:e1009103.
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  123. MDLULI T, Jian N, Slike B, Paquin-Proulx D, et al
    RV144 HIV-1 vaccination impacts post-infection antibody responses.
    PLoS Pathog. 2020;16:e1009101.
    PubMed     Abstract available


  124. WU NC, Yuan M, Bangaru S, Huang D, et al
    A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.
    PLoS Pathog. 2020;16:e1009089.
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  125. LI Z, Hajian C, Greene WC
    Identification of unrecognized host factors promoting HIV-1 latency.
    PLoS Pathog. 2020;16:e1009055.
    PubMed     Abstract available


  126. CHEU RK, Gustin AT, Lee C, Schifanella L, et al
    Impact of vaginal microbiome communities on HIV antiretroviral-based pre-exposure prophylaxis (PrEP) drug metabolism.
    PLoS Pathog. 2020;16:e1009024.
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    November 2020
  127. MORON-LOPEZ S, Telwatte S, Sarabia I, Battivelli E, et al
    Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals.
    PLoS Pathog. 2020;16:e1009060.
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  128. GODOT V, Tcherakian C, Gil L, Cervera-Marzal I, et al
    TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice.
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  129. TAHER H, Mahyari E, Kreklywich C, Uebelhoer LS, et al
    In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome.
    PLoS Pathog. 2020;16:e1008666.
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  130. GELBART M, Harari S, Ben-Ari Y, Kustin T, et al
    Drivers of within-host genetic diversity in acute infections of viruses.
    PLoS Pathog. 2020;16:e1009029.
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  131. GOSWAMI R, Berendam SJ, Li SH, Nelson AN, et al
    Harnessing early life immunity to develop a pediatric HIV vaccine that can protect through adolescence.
    PLoS Pathog. 2020;16:e1008983.
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  132. CARTER JJ, Gardner JM, Poling BP, Welch MM, et al
    Transcriptional analysis of immune response genes during pathogenesis of cytomegalovirus retinitis in mice with murine acquired immunodeficiency syndrome.
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    October 2020
  133. TRYPSTEEN W, Van Cleemput J, Snippenberg WV, Gerlo S, et al
    On the whereabouts of SARS-CoV-2 in the human body: A systematic review.
    PLoS Pathog. 2020;16:e1009037.
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  134. BRICKER KM, Obregon-Perko V, Uddin F, Williams B, et al
    Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation.
    PLoS Pathog. 2020;16:e1008954.
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  135. FRENCH AJ, Natesampillai S, Krogman A, Correia C, et al
    Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2.
    PLoS Pathog. 2020;16:e1008906.
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  136. GUO K, Shen G, Kibbie J, Gonzalez T, et al
    Qualitative Differences Between the IFNalpha subtypes and IFNbeta Influence Chronic Mucosal HIV-1 Pathogenesis.
    PLoS Pathog. 2020;16:e1008986.
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  137. SAHA B, Chisholm D, Kell AM, Mandell MA, et al
    A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5alpha.
    PLoS Pathog. 2020;16:e1009017.
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  138. BOWMAN ER, Cameron CM, Richardson B, Kulkarni M, et al
    Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms.
    PLoS Pathog. 2020;16:e1008869.
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  139. GENOULA M, Marin Franco JL, Maio M, Dolotowicz B, et al
    Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1alpha activation.
    PLoS Pathog. 2020;16:e1008929.
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  140. DAS J, Devadhasan A, Linde C, Broge T, et al
    Mining for humoral correlates of HIV control and latent reservoir size.
    PLoS Pathog. 2020;16:e1008868.
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    September 2020
  141. PANIGRAHI S, Chen B, Fang M, Potashnikova D, et al
    CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis.
    PLoS Pathog. 2020;16:e1008885.
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  142. KRASNOPOLSKY S, Kuzmina A, Taube R
    Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency.
    PLoS Pathog. 2020;16:e1008834.
    PubMed     Abstract available


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