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Articles published in Proc Natl Acad Sci U S A

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    August 2023

  1. Correction for Highland et al., Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
    Proc Natl Acad Sci U S A. 2023;120:e2312510120.
    PubMed    


  2. WANG Z, Petricca J, Liu M, Zhang S, et al
    SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1.
    Proc Natl Acad Sci U S A. 2023;120:e2220472120.
    PubMed     Abstract available


    July 2023
  3. ZHANG P, Falcone S, Tsybovsky Y, Singh M, et al
    Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles.
    Proc Natl Acad Sci U S A. 2023;120:e2305896120.
    PubMed     Abstract available


  4. WAHEED AA, Zhu Y, Agostino E, Naing L, et al
    Neutral sphingomyelinase 2 is required for HIV-1 maturation.
    Proc Natl Acad Sci U S A. 2023;120:e2219475120.
    PubMed     Abstract available


  5. YOO SW, Waheed AA, Deme P, Tohumeken S, et al
    Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
    Proc Natl Acad Sci U S A. 2023;120:e2219543120.
    PubMed     Abstract available


    June 2023
  6. CASANOVA JL
    From second thoughts on the germ theory to a full-blown host theory.
    Proc Natl Acad Sci U S A. 2023;120:e2301186120.
    PubMed     Abstract available


  7. WANG J, Koduru T, Harish B, McCallum SA, et al
    Pressure pushes tRNA(Lys3) into excited conformational states.
    Proc Natl Acad Sci U S A. 2023;120:e2215556120.
    PubMed     Abstract available


  8. MOTTA FC, McGoff K, Moseley RC, Cho CY, et al
    The parasite intraerythrocytic cycle and human circadian cycle are coupled during malaria infection.
    Proc Natl Acad Sci U S A. 2023;120:e2216522120.
    PubMed     Abstract available


  9. MISSON MINDREBO L, Liu H, Ozorowski G, Tran Q, et al
    Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
    Proc Natl Acad Sci U S A. 2023;120:e2216612120.
    PubMed     Abstract available


  10. GUENTHOER J, Lilly M, Starr TN, Dadonaite B, et al
    Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection.
    Proc Natl Acad Sci U S A. 2023;120:e2220948120.
    PubMed     Abstract available


  11. NIKOLAITCHIK OA, Islam S, Kitzrow JP, Duchon A, et al
    HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness.
    Proc Natl Acad Sci U S A. 2023;120:e2305103120.
    PubMed     Abstract available


  12. TADA T, Minnee J, Landau NR
    Vectored immunoprophylaxis and treatment of SARS-CoV-2 infection in a preclinical model.
    Proc Natl Acad Sci U S A. 2023;120:e2303509120.
    PubMed     Abstract available


    May 2023
  13. MARIOTTON J, Cohen E, Zhu A, Auffray C, et al
    TRPV1 activation in human Langerhans cells and T cells inhibits mucosal HIV-1 infection via CGRP-dependent and independent mechanisms.
    Proc Natl Acad Sci U S A. 2023;120:e2302509120.
    PubMed     Abstract available


  14. GOLDBERG BS, Spencer DA, Pandey S, Ordonez T, et al
    Complement contributes to antibody-mediated protection against repeated SHIV challenge.
    Proc Natl Acad Sci U S A. 2023;120:e2221247120.
    PubMed     Abstract available


  15. JUDITH D, Versapuech M, Bejjani F, Palaric M, et al
    ATG5 selectively engages virus-tethered BST2/tetherin in an LC3C-associated pathway.
    Proc Natl Acad Sci U S A. 2023;120:e2217451120.
    PubMed     Abstract available


  16. DASH PK, Chen C, Kaminski R, Su H, et al
    CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice.
    Proc Natl Acad Sci U S A. 2023;120:e2217887120.
    PubMed     Abstract available


  17. HIGHLAND CM, Tan A, Ricana CL, Briggs JAG, et al
    Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
    Proc Natl Acad Sci U S A. 2023;120:e2220545120.
    PubMed     Abstract available


    April 2023
  18. STACEY JCV, Tan A, Lu JM, James LC, et al
    Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
    Proc Natl Acad Sci U S A. 2023;120:e2220557120.
    PubMed     Abstract available


    March 2023
  19. FRITSCHI CJ, Anang S, Gong Z, Mohammadi M, et al
    Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
    Proc Natl Acad Sci U S A. 2023;120:e2222073120.
    PubMed     Abstract available


  20. SHEN Q, Kumari S, Xu C, Jang S, et al
    The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores.
    Proc Natl Acad Sci U S A. 2023;120:e2202815120.
    PubMed     Abstract available


  21. WANG JYJ, Khmelinskaia A, Sheffler W, Miranda MC, et al
    Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
    Proc Natl Acad Sci U S A. 2023;120:e2214556120.
    PubMed     Abstract available


  22. CHAU S, Gao J, Diao AJ, Cao SB, et al
    Diverse yeast antiviral systems prevent lethal pathogenesis caused by the L-A mycovirus.
    Proc Natl Acad Sci U S A. 2023;120:e2208695120.
    PubMed     Abstract available


  23. ETEMAD B, Sun X, Li Y, Melberg M, et al
    HIV post-treatment controllers have distinct immunological and virological features.
    Proc Natl Acad Sci U S A. 2023;120:e2218960120.
    PubMed     Abstract available


    February 2023
  24. BELL BN, Bruun TUJ, Friedland N, Kim PS, et al
    HIV-1 prehairpin intermediate inhibitors show efficacy independent of neutralization tier.
    Proc Natl Acad Sci U S A. 2023;120:e2215792120.
    PubMed     Abstract available


  25. PANDEY A, Wells CR, Stadnytskyi V, Moghadas SM, et al
    Disease burden among Ukrainians forcibly displaced by the 2022 Russian invasion.
    Proc Natl Acad Sci U S A. 2023;120:e2215424120.
    PubMed     Abstract available


  26. TAGAWA T, Oh D, Dremel S, Mahesh G, et al
    A virus-induced circular RNA maintains latent infection of Kaposi's sarcoma herpesvirus.
    Proc Natl Acad Sci U S A. 2023;120:e2212864120.
    PubMed     Abstract available


    January 2023
  27. PANG H, Ouyang J, Yang Z, Shang H, et al
    Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane.
    Proc Natl Acad Sci U S A. 2023;120:e2212991120.
    PubMed     Abstract available


  28. LAGA I, Niu X, Rucinski K, Baral S, et al
    Mapping the number of female sex workers in countries across sub-Saharan Africa.
    Proc Natl Acad Sci U S A. 2023;120:e2200633120.
    PubMed     Abstract available


  29. LUO S, Jing C, Ye AY, Kratochvil S, et al
    Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors.
    Proc Natl Acad Sci U S A. 2023;120:e2217883120.
    PubMed     Abstract available


  30. LI C, Mori LP, Lyu S, Bronson R, et al
    The chaperone protein p32 stabilizes HIV-1 Tat and strengthens the p-TEFb/RNAPII/TAR complex promoting HIV transcription elongation.
    Proc Natl Acad Sci U S A. 2023;120:e2217476120.
    PubMed     Abstract available


    December 2022
  31. WU S, Li H, Ma A
    Exact reaction coordinates for flap opening in HIV-1 protease.
    Proc Natl Acad Sci U S A. 2022;119:e2214906119.
    PubMed     Abstract available


    November 2022
  32. SUZUKI K, Zaunders J, Gates TM, Levert A, et al
    Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury.
    Proc Natl Acad Sci U S A. 2022;119:e2210584119.
    PubMed     Abstract available


    October 2022
  33. SONG Y, Nguyen XN, Kumar A, da Silva C, et al
    Trim69 is a microtubule regulator that acts as a pantropic viral inhibitor.
    Proc Natl Acad Sci U S A. 2022;119:e2211467119.
    PubMed     Abstract available


    September 2022
  34. VILLABONA-ARENAS CJ, Hue S, Baxter JAC, Hall M, et al
    Using phylogenetics to infer HIV-1 transmission direction between known transmission pairs.
    Proc Natl Acad Sci U S A. 2022;119:e2210604119.
    PubMed     Abstract available


  35. LUTZ EA, Agarwal Y, Momin N, Cowles SC, et al
    Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies.
    Proc Natl Acad Sci U S A. 2022;119:e2205983119.
    PubMed     Abstract available


    August 2022
  36. VELU V, Titanji K, Ahmed H, Shetty RD, et al
    PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques.
    Proc Natl Acad Sci U S A. 2022;119:e2202148119.
    PubMed     Abstract available


  37. LY PT, Xu S, Wirawan M, Luo D, et al
    ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition.
    Proc Natl Acad Sci U S A. 2022;119:e2121453119.
    PubMed     Abstract available


    July 2022
  38. SINGH AK, De Wijngaert B, Bijnens M, Uyttersprot K, et al
    Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
    Proc Natl Acad Sci U S A. 2022;119:e2203660119.
    PubMed     Abstract available


  39. YUAN M, Zhu X, He WT, Zhou P, et al
    A broad and potent neutralization epitope in SARS-related coronaviruses.
    Proc Natl Acad Sci U S A. 2022;119:e2205784119.
    PubMed     Abstract available


  40. WALKER-SPERLING V, Digitale JC, Viard M, Martin MP, et al
    Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner.
    Proc Natl Acad Sci U S A. 2022;119:e2205498119.
    PubMed     Abstract available


  41. CADA AK, Pavlin MR, Castillo JP, Tong AB, et al
    Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1.
    Proc Natl Acad Sci U S A. 2022;119:e2204536119.
    PubMed     Abstract available


  42. BALDWIN ET, Gotte M, Tchesnokov EP, Arnold E, et al
    Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition.
    Proc Natl Acad Sci U S A. 2022;119:e2200260119.
    PubMed     Abstract available


  43. CACCURI F, Messali S, Zani A, Campisi G, et al
    HIV-1 mutants expressing B cell clonogenic matrix protein p17 variants are increasing their prevalence worldwide.
    Proc Natl Acad Sci U S A. 2022;119:e2122050119.
    PubMed     Abstract available


    June 2022
  44. SAMAL AB, Green TJ, Saad JS
    Atomic view of the HIV-1 matrix lattice; implications on virus assembly and envelope incorporation.
    Proc Natl Acad Sci U S A. 2022;119:e2200794119.
    PubMed     Abstract available


    May 2022
  45. HORVATH S, Lu AT, Haghani A, Zoller JA, et al
    DNA methylation clocks for dogs and humans.
    Proc Natl Acad Sci U S A. 2022;119:e2120887119.
    PubMed     Abstract available


  46. MANRY J, Bastard P, Gervais A, Le Voyer T, et al
    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
    Proc Natl Acad Sci U S A. 2022;119:e2200413119.
    PubMed     Abstract available


  47. TIAN JB, Yang J, Joslin WC, Flockerzi V, et al
    TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect Gq/11-Gi/o coincidence signals of variable strengths.
    Proc Natl Acad Sci U S A. 2022;119:e2120870119.
    PubMed     Abstract available


  48. TAURA M, Frank JA, Takahashi T, Kong Y, et al
    APOBEC3A regulates transcription from interferon-stimulated response elements.
    Proc Natl Acad Sci U S A. 2022;119:e2011665119.
    PubMed     Abstract available


  49. OLABODE AS, Ng GT, Wade KE, Salnikov M, et al
    Revisiting the recombinant history of HIV-1 group M with dynamic network community detection.
    Proc Natl Acad Sci U S A. 2022;119:e2108815119.
    PubMed     Abstract available


  50. KAVAKLI KC, Rotondi V
    US foreign aid restrictions and maternal and children's health: Evidence from the "Mexico City Policy".
    Proc Natl Acad Sci U S A. 2022;119:e2123177119.
    PubMed     Abstract available


    April 2022

  51. Correction for Lu et al., Screening for gene expression fluctuations reveals latency-promoting agents of HIV.
    Proc Natl Acad Sci U S A. 2022;119:e2203398119.
    PubMed    


  52. SENGUPTA S, Board NL, Wu F, Moskovljevic M, et al
    TCR-mimic bispecific antibodies to target the HIV-1 reservoir.
    Proc Natl Acad Sci U S A. 2022;119:e2123406119.
    PubMed     Abstract available


    March 2022
  53. YU A, Lee EMY, Briggs JAG, Ganser-Pornillos BK, et al
    Strain and rupture of HIV-1 capsids during uncoating.
    Proc Natl Acad Sci U S A. 2022;119:e2117781119.
    PubMed     Abstract available


  54. ZEBERG H
    The major genetic risk factor for severe COVID-19 is associated with protection against HIV.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    February 2022
  55. LIU H, Zheng ZM
    Linking a nuclear lncRNA to cytoplasmic lysosome integrity and cell death.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed    


  56. SWAN DA, Rolland M, Herbeck JT, Schiffer JT, et al
    Evolution during primary HIV infection does not require adaptive immune selection.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  57. WHITE JA, Simonetti FR, Beg S, McMyn NF, et al
    Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  58. NIGHTINGALE K, Potts M, Hunter LM, Fielding CA, et al
    Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  59. YANG B, Jia Y, Meng Y, Xue Y, et al
    SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  60. CHO A, Gaebler C, Olveira T, Ramos V, et al
    Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  61. GEIS FK, Sabo Y, Chen X, Li Y, et al
    CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  62. RUJAS E, Cui H, Burnie J, Aschner CB, et al
    Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  63. WANG S, Zhao L, Zhang X, Zhang J, et al
    Neuropilin-1, a myeloid cell-specific protein, is an inhibitor of HIV-1 infectivity.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  64. SINGH G, Seufzer B, Song Z, Zucko D, et al
    HIV-1 hypermethylated guanosine cap licenses specialized translation unaffected by mTOR.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available



  65. Correction for Shanmugapriya et al., Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed    


    December 2021
  66. NIKOLAITCHIK OA, Liu S, Kitzrow JP, Liu Y, et al
    Selective packaging of HIV-1 RNA genome is guided by the stability of 5' untranslated region polyA stem.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  67. WICHE SALINAS TR, Zhang Y, Sarnello D, Zhyvoloup A, et al
    Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  68. SHEVCHENKO AK, Zhernakova DV, Malov SV, Komissarov A, et al
    Genome-wide association study reveals genetic variants associated with HIV-1C infection in a Botswana study population.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  69. PAQUIN-PROULX D, Lal KG, Phuang-Ngern Y, Creegan M, et al
    Preferential and persistent impact of acute HIV-1 infection on CD4(+) iNKT cells in colonic mucosa.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  70. LEVY R, Zhang P, Bastard P, Dorgham K, et al
    Monoclonal antibody-mediated neutralization of SARS-CoV-2 in an IRF9-deficient child.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  71. ZHANG L, Richards A, Barrasa MI, Hughes SH, et al
    Reply to Briggs et al.: Genomic integration and expression of SARS-CoV-2 sequences can explain prolonged or recurrent viral RNA detection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    October 2021
  72. SHANMUGAPRIYA S, Santos da Silva E, Campbell JA, Boisjoli MP, et al
    Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  73. RAK R, Polonsky M, Eizenberg-Magar I, Mo Y, et al
    Dynamic changes in tRNA modifications and abundance during T cell activation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  74. LEVIN JG, Rein A
    Show your cap or be packaged into HIV-1.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  75. SCHWANDT H, Currie J, Bar M, Banks J, et al
    Inequality in mortality between Black and White Americans by age, place, and cause and in comparison to Europe, 1990 to 2018.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  76. HARDCASTLE M
    QnAs with Joel N. Blankson.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


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