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Articles published in Proc Natl Acad Sci U S A

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    July 2018
  1. VAMVAKA E, Farre G, Molinos-Albert LM, Evans A, et al
    Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm.
    Proc Natl Acad Sci U S A. 2018 Jul 30. pii: 1806022115.
    PubMed     Text format     Abstract available


  2. DAS B, Dobrowolski C, Luttge B, Valadkhan S, et al
    Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir.
    Proc Natl Acad Sci U S A. 2018 Jul 30. pii: 1803468115.
    PubMed     Text format     Abstract available


  3. SHARMA S, Cermakova K, De Rijck J, Demeulemeester J, et al
    Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
    Proc Natl Acad Sci U S A. 2018 Jul 11. pii: 1803909115.
    PubMed     Text format     Abstract available


    June 2018
  4. ALEMAN F, Tzarum N, Kong L, Nagy K, et al
    Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
    Proc Natl Acad Sci U S A. 2018 Jun 28. pii: 1802378115.
    PubMed     Text format     Abstract available


  5. BART SM, Cohen C, Dye JM, Shorter J, et al
    Enhancement of Ebola virus infection by seminal amyloid fibrils.
    Proc Natl Acad Sci U S A. 2018 Jun 25. pii: 1721646115.
    PubMed     Text format     Abstract available


  6. VAN DUYNE R, Freed EO
    HIV-1 packs in PACSIN2 for cell-to-cell spread.
    Proc Natl Acad Sci U S A. 2018 Jun 20. pii: 1808821115.
    PubMed     Text format    


  7. POPOV S, Popova E, Inoue M, Wu Y, et al
    HIV-1 gag recruits PACSIN2 to promote virus spreading.
    Proc Natl Acad Sci U S A. 2018 Jun 11. pii: 1801849115.
    PubMed     Text format     Abstract available


  8. YANG Y, Qu N, Tan J, Rushdi MN, et al
    Roles of Gag-RNA interactions in HIV-1 virus assembly deciphered by single-molecule localization microscopy.
    Proc Natl Acad Sci U S A. 2018 Jun 11. pii: 1805728115.
    PubMed     Text format     Abstract available


    April 2018
  9. DOSENOVIC P, Kara EE, Pettersson AK, McGuire AT, et al
    Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.
    Proc Natl Acad Sci U S A. 2018 Apr 16. pii: 1803457115.
    PubMed     Text format     Abstract available


  10. YOUNIS S, Kamel W, Falkeborn T, Wang H, et al
    Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth.
    Proc Natl Acad Sci U S A. 2018 Apr 2. pii: 1722333115.
    PubMed     Text format     Abstract available


  11. CHEN S, Bonifati S, Qin Z, St Gelais C, et al
    SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-kappaB and interferon pathways.
    Proc Natl Acad Sci U S A. 2018 Apr 2. pii: 1801213115.
    PubMed     Text format     Abstract available


    March 2018

  12. Correction for Kudalkar et al., From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection.
    Proc Natl Acad Sci U S A. 2018 Mar 12. pii: 1803199115.
    PubMed     Text format    


  13. OFOTOKUN I
    Deciphering how HIV-1 weakens and cracks the bone.
    Proc Natl Acad Sci U S A. 2018 Mar 1. pii: 1801555115.
    PubMed     Text format    


    February 2018
  14. WANG Z, Gurule EE, Brennan TP, Gerold JM, et al
    Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane.
    Proc Natl Acad Sci U S A. 2018 Feb 26. pii: 1720665115.
    PubMed     Text format     Abstract available


  15. YOLITZ J, Schwing C, Chang J, Van Ryk D, et al
    Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120.
    Proc Natl Acad Sci U S A. 2018 Feb 20. pii: 1722627115.
    PubMed     Text format     Abstract available


  16. RAYNAUD-MESSINA B, Bracq L, Dupont M, Souriant S, et al
    Bone degradation machinery of osteoclasts: An HIV-1 target that contributes to bone loss.
    Proc Natl Acad Sci U S A. 2018 Feb 20. pii: 1713370115.
    PubMed     Text format     Abstract available


  17. JOGLEKAR AV, Liu Z, Weber JK, Ouyang Y, et al
    T cell receptors for the HIV KK10 epitope from patients with differential immunologic control are functionally indistinguishable.
    Proc Natl Acad Sci U S A. 2018 Feb 7. pii: 1718659115.
    PubMed     Text format     Abstract available


    January 2018
  18. TSAI CT, Robinson PV, Cortez FJ, Elma MLB, et al
    Antibody detection by agglutination-PCR (ADAP) enables early diagnosis of HIV infection by oral fluid analysis.
    Proc Natl Acad Sci U S A. 2018 Jan 22. pii: 1711004115.
    PubMed     Text format     Abstract available


  19. ESMAIL H, Lai RP, Lesosky M, Wilkinson KA, et al
    Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis.
    Proc Natl Acad Sci U S A. 2018 Jan 16. pii: 1711853115.
    PubMed     Text format     Abstract available


  20. VASYLYEVA TI, Liulchuk M, Friedman SR, Sazonova I, et al
    Molecular epidemiology reveals the role of war in the spread of HIV in Ukraine.
    Proc Natl Acad Sci U S A. 2018 Jan 16. pii: 1701447115.
    PubMed     Text format     Abstract available


  21. LOUIE RHY, Kaczorowski KJ, Barton JP, Chakraborty AK, et al
    Fitness landscape of the human immunodeficiency virus envelope protein that is targeted by antibodies.
    Proc Natl Acad Sci U S A. 2018 Jan 8. pii: 1717765115.
    PubMed     Text format     Abstract available


  22. TIAN L, Kim MS, Li H, Wang J, et al
    Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid.
    Proc Natl Acad Sci U S A. 2018 Jan 2. pii: 1719746115.
    PubMed     Text format     Abstract available


    December 2017
  23. KUDALKAR SN, Beloor J, Quijano E, Spasov KA, et al
    From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection.
    Proc Natl Acad Sci U S A. 2017 Dec 26. pii: 1717932115.
    PubMed     Text format     Abstract available


    November 2017
  24. DHARAN A, Opp S, Abdel-Rahim O, Keceli SK, et al
    Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection.
    Proc Natl Acad Sci U S A. 2017 Nov 27. pii: 1712033114.
    PubMed     Text format     Abstract available


  25. PAK AJ, Grime JMA, Sengupta P, Chen AK, et al
    Immature HIV-1 lattice assembly dynamics are regulated by scaffolding from nucleic acid and the plasma membrane.
    Proc Natl Acad Sci U S A. 2017 Nov 7. pii: 201706600.
    PubMed     Text format     Abstract available


    October 2017
  26. DESHMUKH L, Tugarinov V, Louis JM, Clore GM, et al
    Binding kinetics and substrate selectivity in HIV-1 protease-Gag interactions probed at atomic resolution by chemical exchange NMR.
    Proc Natl Acad Sci U S A. 2017 Oct 30. pii: 201716098.
    PubMed     Text format     Abstract available


  27. MENGISTU M, Tang AH, Foulke JS Jr, Blanpied TA, et al
    Patterns of conserved gp120 epitope presentation on attached HIV-1 virions.
    Proc Natl Acad Sci U S A. 2017 Oct 30. pii: 201705074.
    PubMed     Text format     Abstract available


    August 2017
  28. CHAN AH, Lee WG, Spasov KA, Cisneros JA, et al
    Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.
    Proc Natl Acad Sci U S A. 2017 Aug 21. pii: 201711463.
    PubMed     Text format     Abstract available


  29. MAMEDE JI, Cianci GC, Anderson MR, Hope TJ, et al
    Early cytoplasmic uncoating is associated with infectivity of HIV-1.
    Proc Natl Acad Sci U S A. 2017 Aug 7. pii: 201706245.
    PubMed     Text format     Abstract available


    July 2017
  30. DELANEY MK, Malikov V, Chai Q, Zhao G, et al
    Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport.
    Proc Natl Acad Sci U S A. 2017 Jul 31. pii: 201700247.
    PubMed     Text format     Abstract available


  31. HWANG JK, Wang C, Du Z, Meyers RM, et al
    Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies.
    Proc Natl Acad Sci U S A. 2017 Jul 26. pii: 201709203.
    PubMed     Text format     Abstract available


  32. ASGARI S, Schlapbach LJ, Anchisi S, Hammer C, et al
    Severe viral respiratory infections in children with IFIH1 loss-of-function mutations.
    Proc Natl Acad Sci U S A. 2017 Jul 17. pii: 201704259.
    PubMed     Text format     Abstract available


    June 2017
  33. WU WL, Grotefend CR, Tsai MT, Wang YL, et al
    Delta20 IFITM2 differentially restricts X4 and R5 HIV-1.
    Proc Natl Acad Sci U S A. 2017 Jun 19. pii: 201619640.
    PubMed     Text format     Abstract available


    April 2017
  34. WIEGAND A, Spindler J, Hong FF, Shao W, et al
    Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART.
    Proc Natl Acad Sci U S A. 2017 Apr 17. pii: 201617961.
    PubMed     Text format     Abstract available


  35. XIE J, Sok D, Wu NC, Zheng T, et al
    Immunochemical engineering of cell surfaces to generate virus resistance.
    Proc Natl Acad Sci U S A. 2017 Apr 10. pii: 201702764.
    PubMed     Text format     Abstract available


  36. CAI Y, Karaca-Griffin S, Chen J, Tian S, et al
    Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike.
    Proc Natl Acad Sci U S A. 2017 Apr 10. pii: 201700634.
    PubMed     Text format     Abstract available


    March 2017
  37. COREY L, Gray GE
    Preventing acquisition of HIV is the only path to an AIDS-free generation.
    Proc Natl Acad Sci U S A. 2017 Mar 30. pii: 201703236.
    PubMed     Text format    


  38. LIU C, Zhao Z, Fan J, Lyon CJ, et al
    Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring.
    Proc Natl Acad Sci U S A. 2017 Mar 27. pii: 201621360.
    PubMed     Text format     Abstract available


  39. MEDLOCK J, Pandey A, Parpia AS, Tang A, et al
    Effectiveness of UNAIDS targets and HIV vaccination across 127 countries.
    Proc Natl Acad Sci U S A. 2017 Mar 20. pii: 201620788.
    PubMed     Text format     Abstract available


    February 2017
  40. BALDAUF HM, Stegmann L, Schwarz SM, Ambiel I, et al
    Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.
    Proc Natl Acad Sci U S A. 2017 Feb 22. pii: 201613635.
    PubMed     Text format     Abstract available


  41. JAIN N, Lin HC, Morgan CE, Harris ME, et al
    Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution.
    Proc Natl Acad Sci U S A. 2017 Feb 13. pii: 201616371.
    PubMed     Text format     Abstract available


  42. ESFANDYARPOUR R, DiDonato MJ, Yang Y, Durmus NG, et al
    Multifunctional, inexpensive, and reusable nanoparticle-printed biochip for cell manipulation and diagnosis.
    Proc Natl Acad Sci U S A. 2017 Feb 6. pii: 201621318.
    PubMed     Text format     Abstract available


  43. MYLVAGANAM GH, Rios D, Abdelaal HM, Iyer S, et al
    Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
    Proc Natl Acad Sci U S A. 2017 Feb 3. pii: 201621418.
    PubMed     Text format     Abstract available


    January 2017

  44. Correction for Lorenzi et al., Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201619801.
    PubMed     Text format    


  45. IYER SS, Bibollet-Ruche F, Sherrill-Mix S, Learn GH, et al
    Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness.
    Proc Natl Acad Sci U S A. 2017 Jan 9. pii: 201620144.
    PubMed     Text format     Abstract available


    December 2016
  46. BARAFF AJ, McCormick TH, Raftery AE
    Estimating uncertainty in respondent-driven sampling using a tree bootstrap method.
    Proc Natl Acad Sci U S A. 2016 Dec 7. pii: 201617258.
    PubMed     Text format     Abstract available


    November 2016
  47. LORENZI JC, Cohen YZ, Cohn LB, Kreider EF, et al
    Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA.
    Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201617789.
    PubMed     Text format     Abstract available


  48. GANSER LR, Al-Hashimi HM
    HIV-1 leader RNA dimeric interface revealed by NMR.
    Proc Natl Acad Sci U S A. 2016 Nov 11. pii: 201615789.
    PubMed     Text format    


  49. KHARYTONCHYK S, Monti S, Smaldino PJ, Van V, et al
    Transcriptional start site heterogeneity modulates the structure and function of the HIV-1 genome.
    Proc Natl Acad Sci U S A. 2016 Nov 9. pii: 201616627.
    PubMed     Text format     Abstract available


  50. CHANDE A, Cuccurullo EC, Rosa A, Ziglio S, et al
    S2 from equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3.
    Proc Natl Acad Sci U S A. 2016 Nov 1. pii: 201612044.
    PubMed     Text format     Abstract available


    October 2016
  51. CARROLL VA, Lafferty MK, Marchionni L, Bryant JL, et al
    Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice.
    Proc Natl Acad Sci U S A. 2016 Oct 31. pii: 201615258.
    PubMed     Text format     Abstract available


  52. WANG H, Cohen AA, Galimidi RP, Gristick HB, et al
    Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
    Proc Natl Acad Sci U S A. 2016 Oct 31. pii: 201615939.
    PubMed     Text format     Abstract available


  53. SHAFFER JS, Moore PL, Kardar M, Chakraborty AK, et al
    Optimal immunization cocktails can promote induction of broadly neutralizing Abs against highly mutable pathogens.
    Proc Natl Acad Sci U S A. 2016 Oct 24. pii: 201614940.
    PubMed     Text format     Abstract available


  54. LIU S, Xie J, Cheng J, Li B, et al
    Fungal DNA virus infects a mycophagous insect and utilizes it as a transmission vector.
    Proc Natl Acad Sci U S A. 2016 Oct 24. pii: 201608013.
    PubMed     Text format     Abstract available


  55. DESHMUKH L, Louis JM, Ghirlando R, Clore GM, et al
    Transient HIV-1 Gag-protease interactions revealed by paramagnetic NMR suggest origins of compensatory drug resistance mutations.
    Proc Natl Acad Sci U S A. 2016 Oct 17. pii: 201615342.
    PubMed     Text format     Abstract available


  56. KEANE SC, Van V, Frank HM, Sciandra CA, et al
    NMR detection of intermolecular interaction sites in the dimeric 5'-leader of the HIV-1 genome.
    Proc Natl Acad Sci U S A. 2016 Oct 10. pii: 201614785.
    PubMed     Text format     Abstract available


  57. TAM HH, Melo MB, Kang M, Pelet JM, et al
    Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.
    Proc Natl Acad Sci U S A. 2016 Oct 4. pii: 201606050.
    PubMed     Text format     Abstract available


    September 2016
  58. CASSAN E, Arigon-Chifolleau AM, Mesnard JM, Gross A, et al
    Concomitant emergence of the antisense protein gene of HIV-1 and of the pandemic.
    Proc Natl Acad Sci U S A. 2016 Sep 28. pii: 201605739.
    PubMed     Text format     Abstract available


  59. FOREMAN TW, Mehra S, LoBato DN, Malek A, et al
    CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.
    Proc Natl Acad Sci U S A. 2016 Sep 6. pii: 201611987.
    PubMed     Text format     Abstract available


    August 2016
  60. SALIE ZL, Kirby KA, Michailidis E, Marchand B, et al
    Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA).
    Proc Natl Acad Sci U S A. 2016 Aug 3. pii: 201605223.
    PubMed     Text format     Abstract available


    July 2016
  61. DI MICCO A, Frera G, Lugrin J, Jamilloux Y, et al
    AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
    Proc Natl Acad Sci U S A. 2016 Jul 26. pii: 201602419.
    PubMed     Text format     Abstract available


  62. IMAMICHI H, Dewar RL, Adelsberger JW, Rehm CA, et al
    Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy.
    Proc Natl Acad Sci U S A. 2016 Jul 18. pii: 201609057.
    PubMed     Text format     Abstract available


  63. LEWIS CA JR, Crayle J, Zhou S, Swanstrom R, et al
    Cytosine deamination and the precipitous decline of spontaneous mutation during Earth's history.
    Proc Natl Acad Sci U S A. 2016 Jul 5. pii: 201607580.
    PubMed     Text format     Abstract available


    June 2016
  64. HRECKA K, Hao C, Shun MC, Kaur S, et al
    HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins.
    Proc Natl Acad Sci U S A. 2016 Jun 22. pii: 201605023.
    PubMed     Text format     Abstract available


  65. BORKAR AN, Bardaro MF Jr, Camilloni C, Aprile FA, et al
    Structure of a low-population binding intermediate in protein-RNA recognition.
    Proc Natl Acad Sci U S A. 2016 Jun 10. pii: 201521349.
    PubMed     Text format     Abstract available


    May 2016
  66. LI H, Wang S, Kong R, Ding W, et al
    Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.
    Proc Natl Acad Sci U S A. 2016 May 31. pii: 201606636.
    PubMed     Text format     Abstract available


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