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HIV Infection

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 57 articles: HTML format

Single Articles

May 2026
1. ZHU J, Liao Y, Feng M, Song L, et al
   Apoptosis-inducing factor starts its activity within mitochondria revealed by in situ vibrational probes.
   Proc Natl Acad Sci U S A. 2026;123:e2528689123.
   PubMed     Abstract available
   
   
   
2. HUGHES IK, Kharytonchyk S, Ramaswamy S, Jalloh S, et al
   Transcription start site heterogeneity controls MDA5 sensing of unspliced HIV-1 RNAs.
   Proc Natl Acad Sci U S A. 2026;123:e2522948123.
   PubMed     Abstract available
   
   
   
3. TRIPATHI S, Wu L
   HIV-1 Vif-dependent SUMOylation regulates viral RNA splicing.
   Proc Natl Acad Sci U S A. 2026;123:e2611974123.
   PubMed    
   
   
   
4. HERBERT NG, Cromhout G, Bengu N, Fillis R, et al
   Antiretroviral therapy blocks natural selection on protective and disease-susceptible HLA-B alleles in HIV-1 infection.
   Proc Natl Acad Sci U S A. 2026;123:e2502683123.
   PubMed     Abstract available
   
   
   
5. HABIB R, Solieva SO, Lin ZJ, Ghosh S, et al
   Deep mining of the human antibody repertoire identifies frequent and genetically diverse CDRH3 topologies targetable by vaccination.
   Proc Natl Acad Sci U S A. 2026;123:e2532810123.
   PubMed     Abstract available
   
   
   
6. KELENIS DP, Johnson JR, Sidoli S, Emery A, et al
   HIV-1 infection induces Vif-mediated SUMOylation of host RNA splicing factors important for proper viral RNA splicing.
   Proc Natl Acad Sci U S A. 2026;123:e2532659123.
   PubMed     Abstract available
   
   
   April 2026
7. ROMERO EV, Clyde AE, Giorgi EE, Westfall DH, et al
   Recurrent mutations drive rapid HIV escape from two broadly neutralizing antibodies in vivo.
   Proc Natl Acad Sci U S A. 2026;123:e2524021123.
   PubMed     Abstract available
   
   
   
8. VUONG HR, Zhou Q, L Lesko S, Tenneti K, et al
   The biased adenosine-rich content of the HIV-1 genome serves as a molecular signature that facilitates efficient packaging.
   Proc Natl Acad Sci U S A. 2026;123:e2522851123.
   PubMed     Abstract available
   
   
   March 2026
9. GUPTA M, Waltmann C, Renner N, Wang Y, et al
   Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly.
   Proc Natl Acad Sci U S A. 2026;123:e2524995123.
   PubMed     Abstract available
   
   
   December 2025
10. NELSON JAD, Garfinkle SE, Lin ZJ, Park J, et al
    Machine learning enables de novo multiepitope design of Plasmodium falciparum circumsporozoite protein to target trimeric L9 antibody.
    Proc Natl Acad Sci U S A. 2025;122:e2512358122.
    PubMed     Abstract available
    
    
    November 2025
11. BANDINI M, Ghone D, Evans EL 3rd, Suzuki A, et al
    HIV-1 Vif and Vpr cooperatively modulate the cell cycle to maximize per-cell virion production.
    Proc Natl Acad Sci U S A. 2025;122:e2511502122.
    PubMed     Abstract available
    
    
    
12. HU L, Zhang A, Warshel A
    Exploring evolutionary trajectories of drug resistance.
    Proc Natl Acad Sci U S A. 2025;122:e2517715122.
    PubMed     Abstract available
    
    
    
13. MULLER L, Mallick P, Marin-Carballo AB, Donges P, et al
    Testing paradox may explain increased observed prevalence of bacterial STIs among MSM on HIV PrEP: A modeling study.
    Proc Natl Acad Sci U S A. 2025;122:e2524944122.
    PubMed     Abstract available
    
    
    October 2025
14. VADON C, Nguyen XN, Siahaan V, Song Y, et al
    Microtubule remodeling by the innate immune factor Trim69 compromises dynein-dependent migration of HIV virion cores toward the nucleus.
    Proc Natl Acad Sci U S A. 2025;122:e2505128122.
    PubMed     Abstract available
    
    
    
15. KIM S, Travisano KA, Wilder B, Palomares M, et al
    Exceptionally broad HIV-1 neutralization via bispecific antibody-mediated prepositioning.
    Proc Natl Acad Sci U S A. 2025;122:e2517311122.
    PubMed     Abstract available
    
    
    September 2025
16. ALENCAR GF, Mohamed AO, Burnett MG, Jean SS, et al
    Triple checkpoint blockade of PD-1, Tim-3, and Lag-3 enhances adoptive T cell immunotherapy in a mouse model of ovarian cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2419888122.
    PubMed     Abstract available
    
    
    
17. LIU Y, Li P, Zheng YM, Hikichi Y, et al
    IFN-inducible human phospholipid scramblase 1 (PLSCR1) protein restricts HIV-1 infection by inhibiting membrane fusion.
    Proc Natl Acad Sci U S A. 2025;122:e2516527122.
    PubMed     Abstract available
    
    
    
18. WAN Z, Li C, Zhou Y, Yu Y, et al
    Organoid-based neutralization assays reveal a distinctive profile of SARS-CoV-2 antibodies and recapitulate the real-world efficacy.
    Proc Natl Acad Sci U S A. 2025;122:e2509616122.
    PubMed     Abstract available
    
    
    August 2025
19. GU F, Naghavi MH
    Negative interplay between HIV-1 Gag and amyloid precursor protein centers around competition for VPS4A and TSG101.
    Proc Natl Acad Sci U S A. 2025;122:e2503988122.
    PubMed     Abstract available
    
    
    
20. PAMPENA MB, Samer S, Viox EG, Nguyen K, et al
    Therapeutic CD8(+) T cell tissue retention and immunomodulation during ART interruption fail to prevent SIV rebound.
    Proc Natl Acad Sci U S A. 2025;122:e2501037122.
    PubMed     Abstract available
    
    
    
21. LIN X, Cottrell CA, Kalyuzhniy O, Tingle R, et al
    Structural insights into VRC01-class bnAb precursors with diverse light chains elicited in the IAVI G001 human vaccine trial.
    Proc Natl Acad Sci U S A. 2025;122:e2510163122.
    PubMed     Abstract available
    
    
    June 2025
22. MURAKAMI T, Cardoso RS, Manivannan P, Chang YT, et al
    Macropinosomes are a site of HIV-1 entry into primary CD4(+) T cells.
    Proc Natl Acad Sci U S A. 2025;122:e2417676122.
    PubMed     Abstract available
    
    
    May 2025
23. LUK TY, Yim LY, Zhou R, Mo Y, et al
    BRD9 functions as an HIV-1 latency regulatory factor.
    Proc Natl Acad Sci U S A. 2025;122:e2418467122.
    PubMed     Abstract available
    
    
    
24. KOH Y, Vazquez-Rosa E, Gao F, Li H, et al
    Inhibiting 15-PGDH blocks blood-brain barrier deterioration and protects mice from Alzheimer's disease and traumatic brain injury.
    Proc Natl Acad Sci U S A. 2025;122:e2417224122.
    PubMed     Abstract available
    
    
    
25. DARTOIS V, Lan T, Ganapathy US, Wong CF, et al
    Next-generation rifamycins for the treatment of mycobacterial infections.
    Proc Natl Acad Sci U S A. 2025;122:e2423842122.
    PubMed     Abstract available
    
    
    April 2025
26. NCHIOUA R, Kmiec D, Krchlikova V, Mattes S, et al
    Host ZAP activity correlates with the levels of CpG suppression in primate lentiviruses.
    Proc Natl Acad Sci U S A. 2025;122:e2419489122.
    PubMed     Abstract available
    
    
    
27. LI C, Burdick RC, Siddiqui R, Janaka SK, et al
    Lenacapavir disrupts HIV-1 core integrity while stabilizing the capsid lattice.
    Proc Natl Acad Sci U S A. 2025;122:e2420497122.
    PubMed     Abstract available
    
    
    March 2025
28. JAHAN C, Bonnet-Madin L, Machida S, Sobhian B, et al
    Unintegrated HIV-1 DNA recruits cGAS via its histone-binding domain to escape innate immunity.
    Proc Natl Acad Sci U S A. 2025;122:e2424465122.
    PubMed     Abstract available
    
    
    
29. SANG X, Jiao H, Meng Q, Fang X, et al
    Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.
    Proc Natl Acad Sci U S A. 2025;122:e2425795122.
    PubMed     Abstract available
    
    
    February 2025
30. GAO Y, Barton JP
    A binary trait model reveals the fitness effects of HIV-1 escape from T cell responses.
    Proc Natl Acad Sci U S A. 2025;122:e2405379122.
    PubMed     Abstract available
    
    
    
31. MORBIOLI GG, Baillargeon KR, Kalimashe MN, Kana V, et al
    Clinical evaluation of patterned dried plasma spot cards to support quantification of HIV viral load and reflexive genotyping.
    Proc Natl Acad Sci U S A. 2025;122:e2419160122.
    PubMed     Abstract available
    
    
    
32. KING HAD, Brammer D, Lewitus E, Fennessey CM, et al
    SIV monoclonal antibody administration spanning treatment interruption in macaques delays viral rebound and selects escape variants.
    Proc Natl Acad Sci U S A. 2025;122:e2404767122.
    PubMed     Abstract available
    
    
    January 2025
33. NYENHUIS DA, Watanabe SM, Tjandra N, Carter CA, et al
    Tsg101 mimicry of canonical E2 enzymes underlies its role in ubiquitin signaling.
    Proc Natl Acad Sci U S A. 2025;122:e2419542121.
    PubMed     Abstract available
    
    
    December 2024
34. HERRON L, Mondal K, Schneekloth JS Jr, Tiwary P, et al
    Inferring phase transitions and critical exponents from limited observations with thermodynamic maps.
    Proc Natl Acad Sci U S A. 2024;121:e2321971121.
    PubMed     Abstract available
    
    
    
35. ZHANG Y, Schmick SD, Xie L, Ghosh U, et al
    Very broad distribution of beta sheet registries of the HIV gp41 fusion peptide supports mutational robustness for fusion and infection.
    Proc Natl Acad Sci U S A. 2024;121:e2402953121.
    PubMed     Abstract available
    
    
    
36. MITRA R, Usher ET, Dedeoglu S, Crotteau MJ, et al
    Molecular insights into the interaction between a disordered protein and a folded RNA.
    Proc Natl Acad Sci U S A. 2024;121:e2409139121.
    PubMed     Abstract available
    
    
    
37. ABT ER, Lam AK, Noguchi M, Rashid K, et al
    Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire.
    Proc Natl Acad Sci U S A. 2024;121:e2406332121.
    PubMed     Abstract available
    
    
    November 2024
38. SERRANO T, Casartelli N, Ghasemi F, Wioland H, et al
    HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1.
    Proc Natl Acad Sci U S A. 2024;121:e2407835121.
    PubMed     Abstract available
    
    
    October 2024
39. CARRICO AW, Ryan DT, Berona J, Dominguez BS, et al
    HIV, inflammation, and initiation of methamphetamine use in sexual and gender minorities assigned male at birth.
    Proc Natl Acad Sci U S A. 2024;121:e2407046121.
    PubMed     Abstract available
    
    
    
40. ROSENBERG M, Beidelman ET, Chen X, Whiteson Kabudula C, et al
    Effect of a cash transfer intervention on memory decline and dementia probability in older adults in rural South Africa.
    Proc Natl Acad Sci U S A. 2024;121:e2321078121.
    PubMed     Abstract available
    
    
    September 2024
41. BAKER RP, Liu AZ, Casadevall A
    Cell wall melanin impedes growth of the Cryptococcus neoformans polysaccharide capsule by sequestering calcium.
    Proc Natl Acad Sci U S A. 2024;121:e2412534121.
    PubMed     Abstract available
    
    
    
42. HATTORI SI, Bulut H, Hayashi H, Kishimoto N, et al
    Structural and virologic mechanism of the emergence of resistance to M(pro) inhibitors in SARS-CoV-2.
    Proc Natl Acad Sci U S A. 2024;121:e2404175121.
    PubMed     Abstract available
    
    
    
43. CAPOFERRI AA, Wiegand A, Hong F, Jacobs JL, et al
    HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA.
    Proc Natl Acad Sci U S A. 2024;121:e2405210121.
    PubMed     Abstract available
    
    
    August 2024
44. MEHTA K, Yentsch H, Lee J, Yook Y, et al
    Phosphatidylinositol-3-phosphate mediates Arc capsid secretion through the multivesicular body pathway.
    Proc Natl Acad Sci U S A. 2024;121:e2322422121.
    PubMed     Abstract available
    
    
    
45. YASIN S, Lesko SL, Kharytonchyk S, Brown JD, et al
    Role of RNA structural plasticity in modulating HIV-1 genome packaging and translation.
    Proc Natl Acad Sci U S A. 2024;121:e2407400121.
    PubMed     Abstract available
    
    
    July 2024
46. ORTIZ Y, Anasti K, Pane AK, Cronin K, et al
    The CH1 domain influences the expression and antigen sensing of the HIV-specific CH31 IgM-BCR and IgG-BCR.
    Proc Natl Acad Sci U S A. 2024;121:e2404728121.
    PubMed     Abstract available
    
    
    
47. GUNEY MH, Nagalekshmi K, McCauley SM, Carbone C, et al
    IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
    Proc Natl Acad Sci U S A. 2024;121:e2404349121.
    PubMed     Abstract available
    
    
    
48. HU Z, Lopez-Munoz AD, Kosik I, Li T, et al
    Recombinant OC43 SARS-CoV-2 spike replacement virus: An improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays.
    Proc Natl Acad Sci U S A. 2024;121:e2310421121.
    PubMed     Abstract available
    
    
    
49. PURCELL H, Kohler IV, Ciancio A, Mwera J, et al
    Mortality risk information and health-seeking behavior during an epidemic.
    Proc Natl Acad Sci U S A. 2024;121:e2315677121.
    PubMed     Abstract available
    
    
    June 2024
50. SU PA, Chang CH, Yen SB, Wu HY, et al
    Epitranscriptomic cytidine methylation of the hepatitis B viral RNA is essential for viral reverse transcription and particle production.
    Proc Natl Acad Sci U S A. 2024;121:e2400378121.
    PubMed     Abstract available
    
    
    May 2024
51. WU C, Raheem IT, Nahas DD, Citron M, et al
    Stabilized trimeric peptide immunogens of the complete HIV-1 gp41 N-heptad repeat and their use as HIV-1 vaccine candidates.
    Proc Natl Acad Sci U S A. 2024;121:e2317230121.
    PubMed     Abstract available
    
    
    
52. BLANCO A, Coronado RA, Arun N, Ma K, et al
    Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation.
    Proc Natl Acad Sci U S A. 2024;121:e2313823121.
    PubMed     Abstract available
    
    
    April 2024
53. KIZITO F, Nguyen K, Mbonye U, Shukla M, et al
    Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation.
    Proc Natl Acad Sci U S A. 2024;121:e2202003121.
    PubMed     Abstract available
    
    
    
54. SACCHI P, Wright SE, Neoptolemou P, Lampronti GI, et al
    Crystal size, shape, and conformational changes drive both the disappearance and reappearance of ritonavir polymorphs in the mill.
    Proc Natl Acad Sci U S A. 2024;121:e2319127121.
    PubMed     Abstract available
    
    
    
55. BISWAS A, Choudhuri I, Arnold E, Lyumkis D, et al
    Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure.
    Proc Natl Acad Sci U S A. 2024;121:e2316662121.
    PubMed     Abstract available
    
    
    March 2024
56. SHICHIJO T, Yasunaga JI, Sato K, Nosaka K, et al
    Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.
    Proc Natl Acad Sci U S A. 2024;121:e2309925121.
    PubMed     Abstract available
    
    
    
57. OBRIEN SJ
    Legacy of a magic gene-CCR5-?32: From discovery to clinical benefit in a generation.
    Proc Natl Acad Sci U S A. 2024;121:e2321907121.
    PubMed     Abstract available
    
    

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