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  Valvular Heart Disease

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Articles published in N Engl J Med

Retrieve available abstracts of 74 articles:
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Single Articles


    March 2026
  1. KANG DH, Park SJ, Kim GY, Lee S, et al
    Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis at 10 Years.
    N Engl J Med. 2026;394:1167-1174.
    PubMed     Abstract available


    January 2026
  2. KOTANIDIS CP, Eltchaninoff H, Tseng EE, Thourani VH, et al
    Transcatheter or Surgical Aortic-Valve Replacement in Asymptomatic Severe Aortic Stenosis.
    N Engl J Med. 2026;394:195-198.
    PubMed    


    November 2025
  3. ALEONG EF, Chatzizisis YS
    Forehead Venous Pulsations in Severe Tricuspid Regurgitation.
    N Engl J Med. 2025;393:e33.
    PubMed    


    October 2025
  4. LEON MB, Mack MJ, Pibarot P, Hahn RT, et al
    Transcatheter or Surgical Aortic-Valve Replacement in Low-Risk Patients at 7 Years.
    N Engl J Med. 2025 Oct 27. doi: 10.1056/NEJMoa2509766.
    PubMed     Abstract available


    September 2025
  5. DESAI MY, Owens AT, Abraham T, Olivotto I, et al
    Mavacamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy.
    N Engl J Med. 2025;393:961-972.
    PubMed     Abstract available


  6. GARCIA-PAVIA P, Maron MS, Masri A, Merkely B, et al
    Aficamten or Metoprolol Monotherapy for Obstructive Hypertrophic Cardiomyopathy.
    N Engl J Med. 2025;393:949-960.
    PubMed     Abstract available


    June 2025
  7. BLANKENBERG S
    TAVR for Asymptomatic Severe Aortic Stenosis. Reply.
    N Engl J Med. 2025;392:2179-2180.
    PubMed    


  8. GENEREUX P, Schwartz A, Leon MB
    TAVR for Asymptomatic Severe Aortic Stenosis. Reply.
    N Engl J Med. 2025;392:2178-2179.
    PubMed    


  9. BARBANTI M, Costa G
    TAVR for Asymptomatic Severe Aortic Stenosis.
    N Engl J Med. 2025;392:2178.
    PubMed    


  10. AUER J, Ankersmit HJ, Auer L
    TAVR for Asymptomatic Severe Aortic Stenosis.
    N Engl J Med. 2025;392:2177-2178.
    PubMed    


  11. TOGGWEILER S, Loretz L, Henzen C
    TAVR for Asymptomatic Severe Aortic Stenosis.
    N Engl J Med. 2025;392:2177.
    PubMed    


  12. HOFFMAN BU, Ben-Yehuda O
    TAVR for Asymptomatic Severe Aortic Stenosis.
    N Engl J Med. 2025;392:2176-2177.
    PubMed    


  13. NATALE F, Golino P, Cimmino G
    TAVR for Asymptomatic Severe Aortic Stenosis.
    N Engl J Med. 2025;392:2176.
    PubMed    


    March 2025
  14. KHARBANDA RK, Kennedy J, Jamal Z, Dodd M, et al
    Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation.
    N Engl J Med. 2025 Mar 30. doi: 10.1056/NEJMoa2415120.
    PubMed     Abstract available


  15. RAPOSEIRAS-ROUBIN S, Amat-Santos IJ, Rossello X, Gonzalez Ferreiro R, et al
    Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation.
    N Engl J Med. 2025 Mar 29. doi: 10.1056/NEJMoa2500366.
    PubMed     Abstract available


  16. BEN-YEHUDA O
    Aortic Stenosis - When Valve Intervention Is Not Enough.
    N Engl J Med. 2025 Mar 29. doi: 10.1056/NEJMe2503345.
    PubMed    


  17. HAHN RT, Thourani VH, Lurz P
    Transcatheter Valve Replacement in Severe Tricuspid Regurgitation. Reply.
    N Engl J Med. 2025;392:1244-1245.
    PubMed    


  18. TRIPPOLI S, Messori A
    Transcatheter Valve Replacement in Severe Tricuspid Regurgitation.
    N Engl J Med. 2025;392:1244.
    PubMed    


  19. BIONDI-ZOCCAI G, Garcia-Villarreal OA
    Transcatheter Valve Replacement in Severe Tricuspid Regurgitation.
    N Engl J Med. 2025;392:1243-1244.
    PubMed    


  20. BOWDISH ME, Badhwar V, Chikwe J
    Transcatheter Valve Replacement in Severe Tricuspid Regurgitation.
    N Engl J Med. 2025;392:1243.
    PubMed    


  21. KEMPNY A, McCabe C
    Transcatheter Valve Replacement in Severe Tricuspid Regurgitation.
    N Engl J Med. 2025;392:1243.
    PubMed    


  22. BHUGRA P, Fida N
    Mitral Regurgitation from Ischemic Papillary-Muscle Rupture.
    N Engl J Med. 2025;392:e26.
    PubMed    


    February 2025
  23. ANKER SD, Friede T, Khan MS
    Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation. Reply.
    N Engl J Med. 2025;392:725-726.
    PubMed    


  24. MEWTON N, Angoulvant D, Bouleti C
    Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation.
    N Engl J Med. 2025;392:723-725.
    PubMed    


  25. KOMAMURA K, Murohara T, Iwase M
    Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation.
    N Engl J Med. 2025;392:724.
    PubMed    


  26. ANSELMI A, Garcia-Villareal OA, Redberg R
    Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation.
    N Engl J Med. 2025;392:723-724.
    PubMed    


  27. BALDUS S, Doenst T, Rudolph V
    Transcatheter Repair versus Mitral-Valve Surgery for Secondary Mitral Regurgitation. Reply.
    N Engl J Med. 2025;392:722-723.
    PubMed    


  28. DEHARO P, Bernard A, Fauchier L
    Transcatheter Repair versus Mitral-Valve Surgery for Secondary Mitral Regurgitation.
    N Engl J Med. 2025;392:722.
    PubMed    


  29. HSU CK, Lai CC
    Transcatheter Repair versus Mitral-Valve Surgery for Secondary Mitral Regurgitation.
    N Engl J Med. 2025;392:721-722.
    PubMed    


    January 2025
  30. BLANKENBERG S
    Asymptomatic Severe Aortic-Valve Stenosis - To Wait or Not to Wait.
    N Engl J Med. 2025;392:278-279.
    PubMed    


    November 2024
  31. CHIKWE J, Kittleson MM
    Transcatheter Repair or Surgery for Functional Mitral Regurgitation.
    N Engl J Med. 2024;391:1850-1851.
    PubMed    


    October 2024
  32. HAHN RT, Makkar R, Thourani VH, Makar M, et al
    Transcatheter Valve Replacement in Severe Tricuspid Regurgitation.
    N Engl J Med. 2024 Oct 30. doi: 10.1056/NEJMoa2401918.
    PubMed     Abstract available


  33. O'GARA PT
    Early-Stage Results with Transcatheter Tricuspid-Valve Replacement.
    N Engl J Med. 2024 Oct 30. doi: 10.1056/NEJMe2413200.
    PubMed    


  34. GENEREUX P, Schwartz A, Oldemeyer JB, Pibarot P, et al
    Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis.
    N Engl J Med. 2024 Oct 28. doi: 10.1056/NEJMoa2405880.
    PubMed     Abstract available


    September 2024
  35. HERRMANN HC, Mehran R, Tchetche D
    Self-Expanding or Balloon-Expandable TAVR with a Small Aortic Annulus. Reply.
    N Engl J Med. 2024;391:966-967.
    PubMed    


  36. ABBAS AE, Pibarot P, Hahn RT
    Self-Expanding or Balloon-Expandable TAVR with a Small Aortic Annulus.
    N Engl J Med. 2024;391:965-966.
    PubMed    


  37. TERNACLE J, Modine T
    Self-Expanding or Balloon-Expandable TAVR with a Small Aortic Annulus.
    N Engl J Med. 2024;391:965.
    PubMed    


  38. FLEMING TR
    Self-Expanding or Balloon-Expandable TAVR with a Small Aortic Annulus.
    N Engl J Med. 2024;391:965.
    PubMed    


  39. VAN BELLE E, Vincent F, Clavel MA
    Self-Expanding or Balloon-Expandable TAVR with a Small Aortic Annulus.
    N Engl J Med. 2024;391:964.
    PubMed    


    August 2024
  40. RUBIN EJ, Leopold J, Morrissey S
    NEJM at ESC - PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.
    N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMe2410892.
    PubMed    


  41. RUBIN EJ, Leopold J, Morrissey S
    NEJM at ESC - Transcatheter Repair versus Surgery for Secondary Mitral Regurgitation.
    N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMe2410898.
    PubMed    


  42. RUBIN EJ, Leopold J, Morrissey S
    NEJM at ESC - Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation.
    N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMe2410896.
    PubMed    


  43. LONBORG J, Jabbari R, Sabbah M, Veien KT, et al
    PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.
    N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMoa2401513.
    PubMed     Abstract available


  44. BALDUS S, Doenst T, Pfister R, Gummert J, et al
    Transcatheter Repair versus Mitral-Valve Surgery for Secondary Mitral Regurgitation.
    N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMoa2408739.
    PubMed     Abstract available


  45. ANKER SD, Friede T, von Bardeleben RS, Butler J, et al
    Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation.
    N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMoa2314328.
    PubMed     Abstract available


  46. VAN GINKEL DJ, Bor WL, Aarts HM, Dubois C, et al
    Continuation versus Interruption of Oral Anticoagulation during TAVI.
    N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMoa2407794.
    PubMed     Abstract available


  47. MARON MS, Coats CJ, Jacoby DL
    Aficamten for Obstructive Hypertrophic Cardiomyopathy. Reply.
    N Engl J Med. 2024;391:665-666.
    PubMed    


  48. PEDREIRA-BOUZAS J, Pousada-Fonseca A, Fraga D
    Aficamten for Obstructive Hypertrophic Cardiomyopathy.
    N Engl J Med. 2024;391:665.
    PubMed    


  49. LI P
    Aficamten for Obstructive Hypertrophic Cardiomyopathy.
    N Engl J Med. 2024;391:664-665.
    PubMed    


  50. BLANKENBERG S, Seiffert M, Falk V
    Transcatheter or Surgical Treatment of Aortic-Valve Stenosis. Reply.
    N Engl J Med. 2024;391:10.
    PubMed    


  51. LABASTE F, Botea R, Marcheix B
    Transcatheter or Surgical Treatment of Aortic-Valve Stenosis.
    N Engl J Med. 2024;391:575-576.
    PubMed    


  52. AUER J, Lamm G
    Transcatheter or Surgical Treatment of Aortic-Valve Stenosis.
    N Engl J Med. 2024;391:574-575.
    PubMed    


  53. MAZHAR K, Warwick R, Balacumaraswami L
    Transcatheter or Surgical Treatment of Aortic-Valve Stenosis.
    N Engl J Med. 2024;391:574.
    PubMed    


    May 2024
  54. OMMEN SR
    Sixty Years of Hemodynamic Pharmacology in Obstructive Hypertrophic Cardiomyopathy.
    N Engl J Med. 2024;390:1914-1915.
    PubMed    


  55. MARON MS, Masri A, Nassif ME, Barriales-Villa R, et al
    Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy.
    N Engl J Med. 2024;390:1849-1861.
    PubMed     Abstract available


  56. SHAH PB
    Another Early Win for TAVI in Low-Risk Patients.
    N Engl J Med. 2024;390:1623-1625.
    PubMed    


    April 2024
  57. BLANKENBERG S, Seiffert M, Vonthein R, Baumgartner H, et al
    Transcatheter or Surgical Treatment of Aortic-Valve Stenosis.
    N Engl J Med. 2024 Apr 8. doi: 10.1056/NEJMoa2400685.
    PubMed     Abstract available


  58. HERRMANN HC, Mehran R, Blackman DJ, Bailey S, et al
    Self-Expanding or Balloon-Expandable TAVR in Patients with a Small Aortic Annulus.
    N Engl J Med. 2024 Apr 7. doi: 10.1056/NEJMoa2312573.
    PubMed     Abstract available


    February 2024
  59. MACK MJ, Leon MB
    Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years. Reply.
    N Engl J Med. 2024;390:866.
    PubMed    


  60. GASPAROVIC H, Tokic T
    Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years.
    N Engl J Med. 2024;390:865-866.
    PubMed    


    January 2024
  61. ZEN K, Inoue K, Yashige M
    Gastrointestinal Angiodysplasia before and after TAVR. Reply.
    N Engl J Med. 2024;390:95-96.
    PubMed    


  62. NATALE F, Golino P, Cimmino G
    Gastrointestinal Angiodysplasia before and after TAVR.
    N Engl J Med. 2024;390:95.
    PubMed    


    November 2023
  63. LANDMESSER U
    The Changing Landscape of Aortic-Valve Stenosis Management.
    N Engl J Med. 2023;389:2008-2009.
    PubMed    


    October 2023
  64. MACK MJ, Leon MB, Thourani VH, Pibarot P, et al
    Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years.
    N Engl J Med. 2023 Oct 24. doi: 10.1056/NEJMoa2307447.
    PubMed     Abstract available


  65. YASHIGE M, Inoue K, Zen K, Kobayashi R, et al
    Gastrointestinal Angiodysplasia before and after Treatment of Severe Aortic Stenosis.
    N Engl J Med. 2023;389:1530-1532.
    PubMed    


    August 2023
  66. SORAJJA P
    Transcatheter Repair for Patients with Tricuspid Regurgitation. Reply.
    N Engl J Med. 2023;389:865-866.
    PubMed    


  67. GOESSL M
    Transcatheter Repair for Patients with Tricuspid Regurgitation.
    N Engl J Med. 2023;389:865.
    PubMed    


  68. GIRGIS RE, Loyaga-Rendon R, Murphy ET
    Transcatheter Repair for Patients with Tricuspid Regurgitation.
    N Engl J Med. 2023;389:864-865.
    PubMed    


  69. MONDELLINI GM, Verbrugge FH, Guazzi M
    Transcatheter Repair for Patients with Tricuspid Regurgitation.
    N Engl J Med. 2023;389:864.
    PubMed    


    June 2023
  70. MCMURRAY JJV, Metra M
    Transcatheter Repair of Secondary Mitral Regurgitation.
    N Engl J Med. 2023;388:2097-2098.
    PubMed    


    May 2023
  71. ORBAN M, Massberg S
    Transcatheter Therapy for Tricuspid Regurgitation - First Act.
    N Engl J Med. 2023;388:1902-1903.
    PubMed    


  72. HAHN RT
    Tricuspid Regurgitation.
    N Engl J Med. 2023;388:1876-1891.
    PubMed    


    March 2023
  73. STONE GW, Abraham WT, Lindenfeld J, Kar S, et al
    Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation.
    N Engl J Med. 2023 Mar 5. doi: 10.1056/NEJMoa2300213.
    PubMed     Abstract available


  74. SORAJJA P, Whisenant B, Hamid N, Naik H, et al
    Transcatheter Repair for Patients with Tricuspid Regurgitation.
    N Engl J Med. 2023 Mar 4. doi: 10.1056/NEJMoa2300525.
    PubMed     Abstract available


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