Home The Word Brain My Amedeo FAQ Privacy About Flying Publisher   


The Angels Initiative

Stroke prevention


  Bacterial Infections and Mycoses

  Free Subscription


Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 139 articles:
HTML format



Single Articles


    June 2022

  1. Correction for Chiner-Oms et al., Gene evolutionary trajectories in Mycobacterium tuberculosis reveal temporal signs of selection.
    Proc Natl Acad Sci U S A. 2022;119:e2208725119.
    PubMed    


  2. ANAHTAR M, Chan LW, Ko H, Rao A, et al
    Host protease activity classifies pneumonia etiology.
    Proc Natl Acad Sci U S A. 2022;119:e2121778119.
    PubMed     Abstract available


  3. SIEWERT LK, Korotaev A, Sedzicki J, Fromm K, et al
    Identification of the Bartonella autotransporter CFA as a protective antigen and hypervariable target of neutralizing antibodies in mice.
    Proc Natl Acad Sci U S A. 2022;119:e2202059119.
    PubMed     Abstract available


  4. KAMATH PL
    Conserving rhinoceros in the face of disease.
    Proc Natl Acad Sci U S A. 2022;119:e2206438119.
    PubMed    


  5. TSUJIHANA K, Tanegashima K, Santo Y, Yamada H, et al
    Circadian protection against bacterial skin infection by epidermal CXCL14-mediated innate immunity.
    Proc Natl Acad Sci U S A. 2022;119:e2116027119.
    PubMed     Abstract available


  6. DWYER R, Goosen W, Buss P, Kedward S, et al
    Epidemiology of Mycobacterium bovis infection in free-ranging rhinoceros in Kruger National Park, South Africa.
    Proc Natl Acad Sci U S A. 2022;119:e2120656119.
    PubMed     Abstract available


  7. NARCISO AR, Iovino F, Thorsdottir S, Mellroth P, et al
    Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA.
    Proc Natl Acad Sci U S A. 2022;119:e2122386119.
    PubMed     Abstract available


    May 2022
  8. SLAVIN P, Sebbane F
    Emergence and spread of ancestral Yersinia pestis in Late-Neolithic and Bronze-Age Eurasia, ca. 5,000 to 1,500 y B.P.
    Proc Natl Acad Sci U S A. 2022;119:e2204044119.
    PubMed    


    April 2022
  9. ANDRADES VALTUENA A, Neumann GU, Spyrou MA, Musralina L, et al
    Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague.
    Proc Natl Acad Sci U S A. 2022;119:e2116722119.
    PubMed     Abstract available


  10. CHINER-OMS A, Lopez MG, Moreno-Molina M, Furio V, et al
    Gene evolutionary trajectories in Mycobacterium tuberculosis reveal temporal signs of selection.
    Proc Natl Acad Sci U S A. 2022;119:e2113600119.
    PubMed     Abstract available


  11. KOH EI, Oluoch PO, Ruecker N, Proulx MK, et al
    Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.
    Proc Natl Acad Sci U S A. 2022;119:e2201632119.
    PubMed     Abstract available


  12. AMOR DR, Gore J
    Fast growth can counteract antibiotic susceptibility in shaping microbial community resilience to antibiotics.
    Proc Natl Acad Sci U S A. 2022;119:e2116954119.
    PubMed     Abstract available


  13. HERNANDO-AMADO S, Laborda P, Valverde JR, Martinez JL, et al
    Mutational background influences P. aeruginosa ciprofloxacin resistance evolution but preserves collateral sensitivity robustness.
    Proc Natl Acad Sci U S A. 2022;119:e2109370119.
    PubMed     Abstract available


  14. DE BEI O, Marchetti M, Ronda L, Gianquinto E, et al
    Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
    Proc Natl Acad Sci U S A. 2022;119:e2116708119.
    PubMed     Abstract available


  15. LAUGHLIN ZT, Nandi S, Dey D, Zelinskaya N, et al
    50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
    Proc Natl Acad Sci U S A. 2022;119:e2120352119.
    PubMed     Abstract available


    March 2022
  16. PEREIRA MJ, Wager B, Garrigues RJ, Gerlach E, et al
    Lipoproteome screening of the Lyme disease agent identifies inhibitors of antibody-mediated complement killing.
    Proc Natl Acad Sci U S A. 2022;119:e2117770119.
    PubMed     Abstract available


  17. SUN X, Chi H
    Tregs tango with killer cells in acute infection.
    Proc Natl Acad Sci U S A. 2022;119:e2202400119.
    PubMed    


  18. CHEN J, Byun H, Liu R, Jung IJ, et al
    A commensal-encoded genotoxin drives restriction of Vibrio cholerae colonization and host gut microbiome remodeling.
    Proc Natl Acad Sci U S A. 2022;119:e2121180119.
    PubMed     Abstract available


  19. WANG X, Li P, Singh AK, Zhang X, et al
    Remodeling Yersinia pseudotuberculosis to generate a highly immunogenic outer membrane vesicle vaccine against pneumonic plague.
    Proc Natl Acad Sci U S A. 2022;119:e2109667119.
    PubMed     Abstract available


  20. OSMAN MM, Shanahan JK, Chu F, Takaki KK, et al
    The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence.
    Proc Natl Acad Sci U S A. 2022;119:e2122161119.
    PubMed     Abstract available


  21. DOLINA JS, Lee J, Moore EL, Hope JL, et al
    Developmentally distinct CD4(+) Treg lineages shape the CD8(+) T cell response to acute Listeria infection.
    Proc Natl Acad Sci U S A. 2022;119:e2113329119.
    PubMed     Abstract available


  22. KRISHNAN M, Choi J, Jang A, Choi S, et al
    Molecular mechanism underlying the TLR4 antagonistic and antiseptic activities of papiliocin, an insect innate immune response molecule.
    Proc Natl Acad Sci U S A. 2022;119:e2115669119.
    PubMed     Abstract available


    February 2022
  23. CHADDA A, Jensen D, Tomko EJ, Ruiz Manzano A, et al
    Mycobacterium tuberculosis DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  24. TUFFS SW, Goncheva MI, Xu SX, Craig HC, et al
    Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  25. WANG L, Asare E, Shetty AC, Sanchez-Tumbaco F, et al
    Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  26. MEHDIRATTA K, Singh S, Sharma S, Bhosale RS, et al
    Kupyaphores are zinc homeostatic metallophores required for colonization of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  27. SUN S, Roth C, Floyd Averette A, Magwene PM, et al
    Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  28. COOPER C, Peterson EJR, Bailo R, Pan M, et al
    MadR mediates acyl CoA-dependent regulation of mycolic acid desaturation in mycobacteria.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  29. ERCOLI MF, Luu DD, Rim EY, Shigenaga A, et al
    Plant immunity: Rice XA21-mediated resistance to bacterial infection.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  30. SORGELOOS F, Peeters M, Hayashi Y, Borghese F, et al
    A case of convergent evolution: Several viral and bacterial pathogens hijack RSK kinases through a common linear motif.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  31. CHEN X, Schneewind O, Missiakas D
    Engineered human antibodies for the opsonization and killing of Staphylococcus aureus.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  32. VAN HAUWERMEIREN F, Van Opdenbosch N, Van Gorp H, de Vasconcelos N, et al
    Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  33. LEWIN GR, Stocke KS, Lamont RJ, Whiteley M, et al
    A quantitative framework reveals traditional laboratory growth is a highly accurate model of human oral infection.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  34. DAS S, Saqib M, Meng RC, Chittur SV, et al
    Hemochromatosis drives acute lethal intestinal responses to hyperyersiniabactin-producing Yersinia pseudotuberculosis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  35. ZHANG Y, Fu J, Liu S, Wang L, et al
    Coxiella burnetii inhibits host immunity by a protein phosphatase adapted from glycolysis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  36. LI J, Claudi B, Fanous J, Chicherova N, et al
    Tissue compartmentalization enables Salmonella persistence during chemotherapy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  37. MARGOLIS SR, Dietzen PA, Hayes BM, Wilson SC, et al
    The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  38. WOLINSKA KW, Vannier N, Thiergart T, Pickel B, et al
    Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  39. MARTIN MJ, Corey BW, Sannio F, Hall LR, et al
    Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  40. MONTGOMERY MG, Petri J, Spikes TE, Walker JE, et al
    Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  41. ALQARZAEE AA, Chaudhari SS, Islam MM, Kumar V, et al
    Staphylococcal ClpXP protease targets the cellular antioxidant system to eliminate fitness-compromised cells in stationary phase.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  42. BARNIER JP, Meyer J, Kolappan S, Bouzinba-Segard H, et al
    The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  43. SALAMAGA B, Kong L, Pasquina-Lemonche L, Lafage L, et al
    Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  44. PRICE SL, Vadyvaloo V, DeMarco JK, Brady A, et al
    Yersiniabactin contributes to overcoming zinc restriction during Yersinia pestis infection of mammalian and insect hosts.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  45. GRISON CM, Lambey P, Jeannot S, Del Nero E, et al
    Molecular insights into mechanisms of GPCR hijacking by Staphylococcus aureus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  46. Correction for Whitworth et al., Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  47. YU HB, Yang H, Allaire JM, Ma C, et al
    Vasoactive intestinal peptide promotes host defense against enteric pathogens by modulating the recruitment of group 3 innate lymphoid cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  48. SAECKER RM, Chen J, Chiu CE, Malone B, et al
    Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  49. LOPEZ-PEREZ M, Jayakumar JM, Grant TA, Zaragoza-Solas A, et al
    Ecological diversification reveals routes of pathogen emergence in endemic Vibrio vulnificus populations.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  50. QIN H, Zou Z, Anderson D, Sang Y, et al
    The transcription regulator BrsR serves as a network hub of natural competence protein-protein interactions in Streptococcus mutans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  51. BARBIERI R
    Origin, transmission, and evolution of plague over 400 y in Europe.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  52. KESHARI RS, Popescu NI, Silasi R, Regmi G, et al
    Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  53. PEI S, Liljeros F, Shaman J
    Identifying asymptomatic spreaders of antimicrobial-resistant pathogens in hospital settings.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  54. JONES CS, Anderson AC, Clarke AJ
    Mechanism of Staphylococcus aureus peptidoglycan O-acetyltransferase A as an O-acyltransferase.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  55. BRAMANTI B, Wu Y, Yang R, Cui Y, et al
    Assessing the origins of the European Plagues following the Black Death: A synthesis of genomic, historical, and ecological information.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  56. LIM J, Lee JJ, Lee SK, Kim S, et al
    Phosphoenolpyruvate depletion mediates both growth arrest and drug tolerance of Mycobacterium tuberculosis in hypoxia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  57. GOUZY A, Healy C, Black KA, Rhee KY, et al
    Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  58. BARTH VC, Chauhan U, Zeng J, Su X, et al
    Mycobacterium tuberculosis VapC4 toxin engages small ORFs to initiate an integrated oxidative and copper stress response.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  59. LUIZET JB, Raymond J, Lacerda TLS, Barbieux E, et al
    The Brucella effector BspL targets the ER-associated degradation (ERAD) pathway and delays bacterial egress from infected cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  60. KADRY NA, Porsch EA, Shen H, St Geme JW 3rd, et al
    Immunization with HMW1 and HMW2 adhesins protects against colonization by heterologous strains of nontypeable Haemophilus influenzae.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  61. VINCENT CM, Dionne MS
    Disparate regulation of IMD signaling drives sex differences in infection pathology in Drosophila melanogaster.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  62. SHRESTHA E, Coulter JB, Guzman W, Ozbek B, et al
    Oncogenic gene fusions in nonneoplastic precursors as evidence that bacterial infection can initiate prostate cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  63. XI R, Montague J, Lin X, Lu C, et al
    Up-regulation of gasdermin C in mouse small intestine is associated with lytic cell death in enterocytes in worm-induced type 2 immunity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  64. SUN W, Ma X, Wang H, Du Y, et al
    MYO1F regulates antifungal immunity by regulating acetylation of microtubules.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  65. YANG WH, Westman JS, Heithoff DM, Sperandio M, et al
    Neu3 neuraminidase induction triggers intestinal inflammation and colitis in a model of recurrent human food-poisoning.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  66. CHEN KW, Demarco B, Ramos S, Heilig R, et al
    RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  67. ARAGAW WW, Lee BM, Yang X, Zimmerman MD, et al
    Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  68. WU C, Chen YW, Scheible M, Chang C, et al
    Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  69. YAN Q, Zhang W, Lin M, Teymournejad O, et al
    Iron robbery by intracellular pathogen via bacterial effector-induced ferritinophagy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  70. RAYNAUD C, Sheppard D, Berry JL, Gurung I, et al
    PilB from Streptococcus sanguinis is a bimodular type IV pilin with a direct role in adhesion.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  71. DI IULIO J, Bartha I, Spreafico R, Virgin HW, et al
    Transfer transcriptomic signatures for infectious diseases.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  72. DROTT MT, Rush TA, Satterlee TR, Giannone RJ, et al
    Microevolution in the pansecondary metabolome of Aspergillus flavus and its potential macroevolutionary implications for filamentous fungi.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  73. LABUDA JC, Pham OH, Depew CE, Fong KD, et al
    Circulating immunity protects the female reproductive tract from Chlamydia infection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  74. LOFFREDO MR, Savini F, Bobone S, Casciaro B, et al
    Inoculum effect of antimicrobial peptides.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  75. MASISON J, Beezley J, Mei Y, Ribeiro H, et al
    A modular computational framework for medical digital twins.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  76. IM H, Hwang SH, Kim BS, Choi SH, et al
    Pathogenic potential assessment of the Shiga toxin-producing Escherichia coli by a source attribution-considered machine learning model.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  77. ZHANG W, Lin M, Yan Q, Budachetri K, et al
    An intracellular nanobody targeting T4SS effector inhibits Ehrlichia infection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  78. LIU Q, Liu H, Shi L, Gan M, et al
    Local adaptation of Mycobacterium tuberculosis on the Tibetan Plateau.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  79. LI C, Zhou Z, Lumey LH
    Early-life exposure to the Chinese famine and tuberculosis risk: Unrecognized biases from different measures of famine intensity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  80. DONG W, Nie X, Zhu H, Liu Q, et al
    Mycobacterial fatty acid catabolism is repressed by FdmR to sustain lipogenesis and virulence.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  81. KOBAYASHI J, Kawakubo M, Fujii C, Arisaka N, et al
    Cholestenone functions as an antibiotic against Helicobacter pylori by inhibiting biosynthesis of the cell wall component CGL.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  82. SAMPERIO VENTAYOL P, Geiser P, Di Martino ML, Florbrant A, et al
    Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  83. LE VOYER T, Neehus AL, Yang R, Ogishi M, et al
    Inherited deficiency of stress granule ZNFX1 in patients with monocytosis and mycobacterial disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  84. AGGARWAL SD, Lloyd AJ, Yerneni SS, Narciso AR, et al
    A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  85. TEOH WP, Chen X, Laczkovich I, Alonzo F 3rd, et al
    Staphylococcus aureus adapts to the host nutritional landscape to overcome tissue-specific branched-chain fatty acid requirement.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  86. ANGST DC, Tepekule B, Sun L, Bogos B, et al
    Comparing treatment strategies to reduce antibiotic resistance in an in vitro epidemiological setting.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  87. RIMBARA E, Suzuki M, Matsui H, Nakamura M, et al
    Isolation and characterization of Helicobacter suis from human stomach.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  88. SINGH-BABAK SD, Babak T, Fraser HB, Johnson AD, et al
    Lineage-specific selection and the evolution of virulence in the Candida clade.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  89. FIEBIG A, Vrentas CE, Le T, Huebner M, et al
    Quantification of Brucella abortus population structure in a natural host.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  90. WHITWORTH LJ, Troll R, Pagan AJ, Roca FJ, et al
    Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  91. BERRYHILL BA, Huseby DL, McCall IC, Hughes D, et al
    Evaluating the potential efficacy and limitations of a phage for joint antibiotic and phage therapy of Staphylococcus aureus infections.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  92. WU J, Bao C, Reinhardt RL, Abraham SN, et al
    Local induction of bladder Th1 responses to combat urinary tract infections.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  93. CHIANG N, de la Rosa X, Libreros S, Pan H, et al
    Cysteinyl-specialized proresolving mediators link resolution of infectious inflammation and tissue regeneration via TRAF3 activation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  94. CHANG YL, Rossetti M, Gjertson DW, Rubbi L, et al
    Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  95. RAFFA N, Won TH, Sukowaty A, Candor K, et al
    Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  96. HUEMER M, Mairpady Shambat S, Bergada-Pijuan J, Soderholm S, et al
    Molecular reprogramming and phenotype switching in Staphylococcus aureus lead to high antibiotic persistence and affect therapy success.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  97. CRUZ AR, Boer MAD, Strasser J, Zwarthoff SA, et al
    Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  98. HANNA CC, Ashhurst AS, Quan D, Maxwell JWC, et al
    Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  99. WANG Y, He K, Sheng B, Lei X, et al
    The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  100. EZENWA VO, Budischak SA, Buss P, Seguel M, et al
    Natural resistance to worms exacerbates bovine tuberculosis severity independently of worm coinfection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  101. HOU P, Jia P, Yang K, Li Z, et al
    An unconventional role of an ASB family protein in NF-kappaB activation and inflammatory response during microbial infection and colitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  102. SU H, Liu Q, Bian X, Wang S, et al
    Synthesis and delivery of Streptococcus pneumoniae capsular polysaccharides by recombinant attenuated Salmonella vaccines.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  103. SATERIALE A, Gullicksrud JA, Engiles JB, McLeod BI, et al
    The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  104. TOWELL AM, Feuillie C, Vitry P, Da Costa TM, et al
    Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  105. PRASAD JM, Negron O, Du X, Mullins ES, et al
    Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  106. OLDENKAMP R, Schultsz C, Mancini E, Cappuccio A, et al
    Filling the gaps in the global prevalence map of clinical antimicrobial resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  107. INOMATA M, Xu S, Chandra P, Meydani SN, et al
    Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging.
    Proc Natl Acad Sci U S A. 2020;117:33561-33569.
    PubMed     Abstract available


  108. MAN K, Bowman C, Braverman KN, Escalante V, et al
    A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance.
    Proc Natl Acad Sci U S A. 2020;117:32029-32037.
    PubMed     Abstract available


  109. D'MELLO A, Riegler AN, Martinez E, Beno SM, et al
    An in vivo atlas of host-pathogen transcriptomes during Streptococcus pneumoniae colonization and disease.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2010428117.
    PubMed     Abstract available


  110. ZHONG W, Shi Z, Mahadevegowda SH, Liu B, et al
    Designer broad-spectrum polyimidazolium antibiotics.
    Proc Natl Acad Sci U S A. 2020;117:31376-31385.
    PubMed     Abstract available


  111. AUNINS TR, Erickson KE, Chatterjee A
    Transcriptome-based design of antisense inhibitors potentiates carbapenem efficacy in CRE Escherichia coli.
    Proc Natl Acad Sci U S A. 2020;117:30699-30709.
    PubMed     Abstract available


  112. LIM C, Berk JM, Blaise A, Bircher J, et al
    Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi.
    Proc Natl Acad Sci U S A. 2020;117:30380-30390.
    PubMed     Abstract available


    November 2020
  113. AKHADE AS, Atif SM, Lakshmi BS, Dikshit N, et al
    Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
    Proc Natl Acad Sci U S A. 2020;117:29811-29822.
    PubMed     Abstract available


  114. ZHANG H, Zoued A, Liu X, Sit B, et al
    Type I interferon remodels lysosome function and modifies intestinal epithelial defense.
    Proc Natl Acad Sci U S A. 2020;117:29862-29871.
    PubMed     Abstract available


  115. ZULAUF KE, Kirby JE
    Discovery of small-molecule inhibitors of multidrug-resistance plasmid maintenance using a high-throughput screening approach.
    Proc Natl Acad Sci U S A. 2020;117:29839-29850.
    PubMed     Abstract available


  116. HENRIQUES P, Dello Iacono L, Gimeno A, Biolchi A, et al
    Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide.
    Proc Natl Acad Sci U S A. 2020;117:29795-29802.
    PubMed     Abstract available


  117. SENDER V, Hentrich K, Pathak A, Tan Qian Ler A, et al
    Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2012265117.
    PubMed     Abstract available


  118. SHEIKH A, Tumala B, Vickers TJ, Alvarado D, et al
    CEACAMs serve as toxin-stimulated receptors for enterotoxigenic Escherichia coli.
    Proc Natl Acad Sci U S A. 2020;117:29055-29062.
    PubMed     Abstract available


  119. LILIC M, Chen J, Boyaci H, Braffman N, et al
    The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
    Proc Natl Acad Sci U S A. 2020 Nov 16. pii: 2013706117.
    PubMed     Abstract available


  120. GUELLIL M, Kersten O, Namouchi A, Luciani S, et al
    A genomic and historical synthesis of plague in 18th century Eurasia.
    Proc Natl Acad Sci U S A. 2020;117:28328-28335.
    PubMed     Abstract available


  121. DE GRYSE GMA, Khuong TV, Descamps B, Van Den Broeck W, et al
    The shrimp nephrocomplex serves as a major portal of pathogen entry and is involved in the molting process.
    Proc Natl Acad Sci U S A. 2020;117:28374-28383.
    PubMed     Abstract available


  122. EARN DJD, Ma J, Poinar H, Dushoff J, et al
    Acceleration of plague outbreaks in the second pandemic.
    Proc Natl Acad Sci U S A. 2020;117:27703-27711.
    PubMed     Abstract available


  123. FLEEMAN RM, Macias LA, Brodbelt JS, Davies BW, et al
    Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae.
    Proc Natl Acad Sci U S A. 2020;117:27620-27626.
    PubMed     Abstract available


  124. NGO VL, Abo H, Kuczma M, Szurek E, et al
    IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria.
    Proc Natl Acad Sci U S A. 2020;117:27540-27548.
    PubMed     Abstract available


    October 2020
  125. SILVA ON, Torres MDT, Cao J, Alves ESF, et al
    Repurposing a peptide toxin from wasp venom into antiinfectives with dual antimicrobial and immunomodulatory properties.
    Proc Natl Acad Sci U S A. 2020;117:26936-26945.
    PubMed     Abstract available


  126. SORG RA, Gallay C, Van Maele L, Sirard JC, et al
    Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae.
    Proc Natl Acad Sci U S A. 2020 Oct 21. pii: 1920015117.
    PubMed     Abstract available


  127. MACHELART A, Willemart K, Zuniga-Ripa A, Godard T, et al
    Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway.
    Proc Natl Acad Sci U S A. 2020;117:26374-26381.
    PubMed     Abstract available


  128. CHENG Q, Trangucci R, Nelson KN, Fu W, et al
    Prenatal and early-life exposure to the Great Chinese Famine increased the risk of tuberculosis in adulthood across two generations.
    Proc Natl Acad Sci U S A. 2020 Oct 19. pii: 2008336117.
    PubMed     Abstract available


  129. HAMAOUI D, Cosse MM, Mohan J, Lystad AH, et al
    The Chlamydia effector CT622/TaiP targets a nonautophagy related function of ATG16L1.
    Proc Natl Acad Sci U S A. 2020 Oct 14. pii: 2005389117.
    PubMed     Abstract available


  130. GENIN A, Levy L, Sharon G, Raitsos DE, et al
    Rapid onsets of warming events trigger mass mortality of coral reef fish.
    Proc Natl Acad Sci U S A. 2020;117:25378-25385.
    PubMed     Abstract available


  131. DAVID S, Cohen V, Reuter S, Sheppard AE, et al
    Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniae.
    Proc Natl Acad Sci U S A. 2020;117:25043-25054.
    PubMed     Abstract available



  132. Correction for Wang et al., Regenerative therapy based on miRNA-302 mimics for enhancing host recovery from pneumonia caused by Streptococcus pneumoniae.
    Proc Natl Acad Sci U S A. 2020 Oct 5. pii: 2019647117.
    PubMed    


    September 2020
  133. SANZ J, Maurizio PL, Snyder-Mackler N, Simons ND, et al
    Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaques.
    Proc Natl Acad Sci U S A. 2020;117:23317-23322.
    PubMed     Abstract available


  134. PETERSON BN, Portman JL, Feng Y, Wang J, et al
    Secondary structure of the mRNA encoding listeriolysin O is essential to establish the replicative niche of L. monocytogenes.
    Proc Natl Acad Sci U S A. 2020;117:23774-23781.
    PubMed     Abstract available


  135. MICOLI F, Bjarnarson SP, Arcuri M, Aradottir Pind AA, et al
    Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine.
    Proc Natl Acad Sci U S A. 2020 Sep 8. pii: 2005857117.
    PubMed     Abstract available


    August 2020
  136. PRECIADO-LLANES L, Aulicino A, Canals R, Moynihan PJ, et al
    Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.
    Proc Natl Acad Sci U S A. 2020;117:20717-20728.
    PubMed     Abstract available


  137. VIEGAS J
    Profile of Paul E. Turner.
    Proc Natl Acad Sci U S A. 2020;117:18906-18908.
    PubMed    


  138. LAKSHMAIAH NARAYANA J, Mishra B, Lushnikova T, Wu Q, et al
    Two distinct amphipathic peptide antibiotics with systemic efficacy.
    Proc Natl Acad Sci U S A. 2020;117:19446-19454.
    PubMed     Abstract available


  139. ROBLIN C, Chiumento S, Bornet O, Nouailler M, et al
    The unusual structure of Ruminococcin C1 antimicrobial peptide confers clinical properties.
    Proc Natl Acad Sci U S A. 2020;117:19168-19177.
    PubMed     Abstract available


Thank you for your interest in scientific medicine.


AMEDEO Bacterial Infections and Mycoses is free of charge.
This policy is made possible thanks to a media sponsorship by Boehringer Ingelheim.

Design: