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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 32 articles:
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    September 2019
  1. GE C, Huang H, Huang F, Yang T, et al
    Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload.
    Proc Natl Acad Sci U S A. 2019 Sep 5. pii: 1908998116.
    PubMed     Text format     Abstract available


    May 2019
  2. MA L, Pak ML, Ou J, Yu J, et al
    Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells.
    Proc Natl Acad Sci U S A. 2019 May 8. pii: 1903550116.
    PubMed     Text format     Abstract available


  3. HORIBATA S, Gui G, Lack J, DeStefano CB, et al
    Heterogeneity in refractory acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2019 May 7. pii: 1902375116.
    PubMed     Text format     Abstract available


    March 2019
  4. SCHIAVON V, Duchez S, Branchtein M, How-Kit A, et al
    Microenvironment tailors nTreg structure and function.
    Proc Natl Acad Sci U S A. 2019;116:6298-6307.
    PubMed     Text format     Abstract available


    February 2019
  5. POULARD C, Kim HN, Fang M, Kruth K, et al
    Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1816254116.
    PubMed     Text format     Abstract available


  6. CHEN XJ, Zhang WN, Chen B, Xi WD, et al
    Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-kappaB repressing factor.
    Proc Natl Acad Sci U S A. 2019;116:2220-2225.
    PubMed     Text format     Abstract available


    January 2019
  7. LEUNG KK, Nguyen A, Shi T, Tang L, et al
    Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.
    Proc Natl Acad Sci U S A. 2019;116:695-700.
    PubMed     Text format     Abstract available


    December 2018
  8. LIU N, Song J, Xie Y, Wang XL, et al
    Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.
    Proc Natl Acad Sci U S A. 2018 Dec 28. pii: 1809327116.
    PubMed     Text format     Abstract available


    November 2018
  9. LI JF, Dai YT, Lilljebjorn H, Shen SH, et al
    Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.
    Proc Natl Acad Sci U S A. 2018 Nov 28. pii: 1814397115.
    PubMed     Text format     Abstract available


  10. QU K, Glass B, Dolezal M, Schur FKM, et al
    Structure and architecture of immature and mature murine leukemia virus capsids.
    Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 1811580115.
    PubMed     Text format     Abstract available


  11. LOVAT F, Fassan M, Sacchi D, Ranganathan P, et al
    Knockout of both miR-15/16 loci induces acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 1814980115.
    PubMed     Text format     Abstract available


    October 2018
  12. KNECHT KM, Buzovetsky O, Schneider C, Thomas D, et al
    The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.
    Proc Natl Acad Sci U S A. 2018;115:E10022-E10031.
    PubMed     Text format     Abstract available


  13. DAS P, Veazey KJ, Van HT, Kaushik S, et al
    Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches.
    Proc Natl Acad Sci U S A. 2018;115:E10137-E10146.
    PubMed     Text format     Abstract available


  14. FEI DL, Zhen T, Durham B, Ferrarone J, et al
    Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.
    Proc Natl Acad Sci U S A. 2018 Oct 15. pii: 1812669115.
    PubMed     Text format     Abstract available


  15. KATSUMURA KR, Mehta C, Hewitt KJ, Soukup AA, et al
    Human leukemia mutations corrupt but do not abrogate GATA-2 function.
    Proc Natl Acad Sci U S A. 2018 Oct 9. pii: 1813015115.
    PubMed     Text format     Abstract available


    September 2018
  16. JAMROG L, Chemin G, Fregona V, Coster L, et al
    PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.
    Proc Natl Acad Sci U S A. 2018 Sep 26. pii: 1721678115.
    PubMed     Text format     Abstract available


    May 2018
  17. ANCHANG B, Davis KL, Fienberg HG, Williamson BD, et al
    DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity.
    Proc Natl Acad Sci U S A. 2018;115:E4294-E4303.
    PubMed     Text format     Abstract available


    April 2018
  18. WEI J, Bera TK, Liu XF, Zhou Q, et al
    Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity.
    Proc Natl Acad Sci U S A. 2018;115:E3501-E3508.
    PubMed     Text format     Abstract available


    March 2018
  19. POLLOCK SB, Hu A, Mou Y, Martinko AJ, et al
    Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.
    Proc Natl Acad Sci U S A. 2018;115:2836-2841.
    PubMed     Text format     Abstract available


    February 2018
  20. ZEISIG BB, So CWE
    MLL-AF4, a double-edged sword for iPSC respecification into HSPCs.
    Proc Natl Acad Sci U S A. 2018;115:1964-1966.
    PubMed     Text format    


  21. MAHGOUB M, Yasunaga JI, Iwami S, Nakaoka S, et al
    Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells.
    Proc Natl Acad Sci U S A. 2018;115:E1269-E1278.
    PubMed     Text format     Abstract available


  22. MULLER F, Cunningham T, Stookey S, Tai CH, et al
    5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox.
    Proc Natl Acad Sci U S A. 2018 Feb 5. pii: 1714512115.
    PubMed     Text format     Abstract available


    January 2018
  23. TAN Q, Brunetti L, Rousseaux MWC, Lu HC, et al
    Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
    Proc Natl Acad Sci U S A. 2018 Jan 30. pii: 1716452115.
    PubMed     Text format     Abstract available


  24. MAZOR R, King EM, Onda M, Cuburu N, et al
    Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity.
    Proc Natl Acad Sci U S A. 2018;115:E733-E742.
    PubMed     Text format     Abstract available


    December 2017
  25. CHEN B, Jiang L, Zhong ML, Li JF, et al
    Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2017 Dec 26. pii: 1717125115.
    PubMed     Text format     Abstract available


    October 2017
  26. KANJEE U, Gruring C, Chaand M, Lin KM, et al
    CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion.
    Proc Natl Acad Sci U S A. 2017;114:E9356-E9365.
    PubMed     Text format     Abstract available


    September 2017
  27. RASSENTI LZ, Balatti V, Ghia EM, Palamarchuk A, et al
    MicroRNA dysregulation to identify therapeutic target combinations for chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201708264.
    PubMed     Text format     Abstract available


    May 2017
  28. PAPAIOANNOU D, Shen C, Nicolet D, McNeil B, et al
    Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2017 May 22. pii: 201703142.
    PubMed     Text format     Abstract available


  29. DAI YJ, Wang YY, Huang JY, Xia L, et al
    Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201703476.
    PubMed     Text format     Abstract available


  30. SCHWARTZMAN O, Savino AM, Gombert M, Palmi C, et al
    Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201702489.
    PubMed     Text format     Abstract available


    March 2017
  31. FABBRI G, Holmes AB, Viganotti M, Scuoppo C, et al
    Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2017 Mar 17. pii: 201702564.
    PubMed     Text format     Abstract available


    December 2016
  32. LEMONNIER F, Cairns RA, Inoue S, Li WY, et al
    The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
    Proc Natl Acad Sci U S A. 2016 Dec 12. pii: 201617929.
    PubMed     Text format     Abstract available


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