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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 37 articles:
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Single Articles


    May 2020
  1. LOVAT F, Nigita G, Distefano R, Nakamura T, et al
    Combined loss of function of two different loci of miR-15/16 drives the pathogenesis of acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2020 May 18. pii: 2003597117.
    PubMed     Abstract available


  2. NAGASAKA M, Yamagishi M, Yagishita N, Araya N, et al
    Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.
    Proc Natl Acad Sci U S A. 2020 May 11. pii: 1920346117.
    PubMed     Abstract available


    November 2019
  3. AGARWAL A, Bolosky WJ, Wilson DB, Eide CA, et al
    Differentiation of leukemic blasts is not completely blocked in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2019 Nov 21. pii: 1904091116.
    PubMed     Abstract available


  4. VENEZIANO D, Tomasello L, Balatti V, Palamarchuk A, et al
    Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2019 Nov 13. pii: 1913695116.
    PubMed     Abstract available


    September 2019
  5. GE C, Huang H, Huang F, Yang T, et al
    Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload.
    Proc Natl Acad Sci U S A. 2019 Sep 5. pii: 1908998116.
    PubMed     Abstract available


    July 2019
  6. KIM JH, Penson AV, Taylor BS, Petrini JHJ, et al
    Nbn-Mre11 interaction is required for tumor suppression and genomic integrity.
    Proc Natl Acad Sci U S A. 2019;116:15178-15183.
    PubMed     Abstract available


    May 2019
  7. MA L, Pak ML, Ou J, Yu J, et al
    Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells.
    Proc Natl Acad Sci U S A. 2019 May 8. pii: 1903550116.
    PubMed     Abstract available


  8. HORIBATA S, Gui G, Lack J, DeStefano CB, et al
    Heterogeneity in refractory acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2019 May 7. pii: 1902375116.
    PubMed     Abstract available


    March 2019
  9. SCHIAVON V, Duchez S, Branchtein M, How-Kit A, et al
    Microenvironment tailors nTreg structure and function.
    Proc Natl Acad Sci U S A. 2019;116:6298-6307.
    PubMed     Abstract available


    February 2019
  10. POULARD C, Kim HN, Fang M, Kruth K, et al
    Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1816254116.
    PubMed     Abstract available


  11. CHEN XJ, Zhang WN, Chen B, Xi WD, et al
    Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-kappaB repressing factor.
    Proc Natl Acad Sci U S A. 2019;116:2220-2225.
    PubMed     Abstract available


    January 2019
  12. LEUNG KK, Nguyen A, Shi T, Tang L, et al
    Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.
    Proc Natl Acad Sci U S A. 2019;116:695-700.
    PubMed     Abstract available


    December 2018
  13. LIU N, Song J, Xie Y, Wang XL, et al
    Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.
    Proc Natl Acad Sci U S A. 2018 Dec 28. pii: 1809327116.
    PubMed     Abstract available


    November 2018
  14. LI JF, Dai YT, Lilljebjorn H, Shen SH, et al
    Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.
    Proc Natl Acad Sci U S A. 2018 Nov 28. pii: 1814397115.
    PubMed     Abstract available


  15. QU K, Glass B, Dolezal M, Schur FKM, et al
    Structure and architecture of immature and mature murine leukemia virus capsids.
    Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 1811580115.
    PubMed     Abstract available


  16. LOVAT F, Fassan M, Sacchi D, Ranganathan P, et al
    Knockout of both miR-15/16 loci induces acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 1814980115.
    PubMed     Abstract available


    October 2018
  17. KNECHT KM, Buzovetsky O, Schneider C, Thomas D, et al
    The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.
    Proc Natl Acad Sci U S A. 2018;115:E10022-E10031.
    PubMed     Abstract available


  18. DAS P, Veazey KJ, Van HT, Kaushik S, et al
    Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches.
    Proc Natl Acad Sci U S A. 2018;115:E10137-E10146.
    PubMed     Abstract available


  19. FEI DL, Zhen T, Durham B, Ferrarone J, et al
    Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.
    Proc Natl Acad Sci U S A. 2018 Oct 15. pii: 1812669115.
    PubMed     Abstract available


  20. KATSUMURA KR, Mehta C, Hewitt KJ, Soukup AA, et al
    Human leukemia mutations corrupt but do not abrogate GATA-2 function.
    Proc Natl Acad Sci U S A. 2018 Oct 9. pii: 1813015115.
    PubMed     Abstract available


    September 2018
  21. JAMROG L, Chemin G, Fregona V, Coster L, et al
    PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.
    Proc Natl Acad Sci U S A. 2018 Sep 26. pii: 1721678115.
    PubMed     Abstract available


    May 2018
  22. ANCHANG B, Davis KL, Fienberg HG, Williamson BD, et al
    DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity.
    Proc Natl Acad Sci U S A. 2018;115:E4294-E4303.
    PubMed     Abstract available


    April 2018
  23. WEI J, Bera TK, Liu XF, Zhou Q, et al
    Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity.
    Proc Natl Acad Sci U S A. 2018;115:E3501-E3508.
    PubMed     Abstract available


    March 2018
  24. POLLOCK SB, Hu A, Mou Y, Martinko AJ, et al
    Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.
    Proc Natl Acad Sci U S A. 2018;115:2836-2841.
    PubMed     Abstract available


    February 2018
  25. ZEISIG BB, So CWE
    MLL-AF4, a double-edged sword for iPSC respecification into HSPCs.
    Proc Natl Acad Sci U S A. 2018;115:1964-1966.
    PubMed    


  26. MAHGOUB M, Yasunaga JI, Iwami S, Nakaoka S, et al
    Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells.
    Proc Natl Acad Sci U S A. 2018;115:E1269-E1278.
    PubMed     Abstract available


  27. MULLER F, Cunningham T, Stookey S, Tai CH, et al
    5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox.
    Proc Natl Acad Sci U S A. 2018 Feb 5. pii: 1714512115.
    PubMed     Abstract available


    January 2018
  28. TAN Q, Brunetti L, Rousseaux MWC, Lu HC, et al
    Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
    Proc Natl Acad Sci U S A. 2018 Jan 30. pii: 1716452115.
    PubMed     Abstract available


  29. MAZOR R, King EM, Onda M, Cuburu N, et al
    Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity.
    Proc Natl Acad Sci U S A. 2018;115:E733-E742.
    PubMed     Abstract available


    December 2017
  30. CHEN B, Jiang L, Zhong ML, Li JF, et al
    Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2017 Dec 26. pii: 1717125115.
    PubMed     Abstract available


    October 2017
  31. KANJEE U, Gruring C, Chaand M, Lin KM, et al
    CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion.
    Proc Natl Acad Sci U S A. 2017;114:E9356-E9365.
    PubMed     Abstract available


    September 2017
  32. RASSENTI LZ, Balatti V, Ghia EM, Palamarchuk A, et al
    MicroRNA dysregulation to identify therapeutic target combinations for chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201708264.
    PubMed     Abstract available


    May 2017
  33. PAPAIOANNOU D, Shen C, Nicolet D, McNeil B, et al
    Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2017 May 22. pii: 201703142.
    PubMed     Abstract available


  34. DAI YJ, Wang YY, Huang JY, Xia L, et al
    Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201703476.
    PubMed     Abstract available


  35. SCHWARTZMAN O, Savino AM, Gombert M, Palmi C, et al
    Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201702489.
    PubMed     Abstract available


    March 2017
  36. FABBRI G, Holmes AB, Viganotti M, Scuoppo C, et al
    Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2017 Mar 17. pii: 201702564.
    PubMed     Abstract available


    December 2016
  37. LEMONNIER F, Cairns RA, Inoue S, Li WY, et al
    The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
    Proc Natl Acad Sci U S A. 2016 Dec 12. pii: 201617929.
    PubMed     Abstract available


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