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Liver Diseases

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 42 articles: HTML format

Single Articles

April 2024
1. GU L, Du Y, Chen J, Hasan MN, et al
   Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance.
   Proc Natl Acad Sci U S A. 2024;121:e2320934121.
   PubMed     Abstract available
   
   
   February 2024
2. DAS A, Cheng H, Wang Y, Kinch LN, et al
   The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3.
   Proc Natl Acad Sci U S A. 2024;121:e2312291121.
   PubMed     Abstract available
   
   
   January 2024
3. HULLAHALLI K, Dailey KG, Hasegawa Y, Johnson WE, et al
   Reverse transcriptase inhibitors prevent liver abscess formation during Escherichia coli bloodstream infection.
   Proc Natl Acad Sci U S A. 2024;121:e2319162121.
   PubMed     Abstract available
   
   
   December 2023
4. SAKUMA I, Gaspar RC, Luukkonen PK, Kahn M, et al
   Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition.
   Proc Natl Acad Sci U S A. 2023;120:e2312666120.
   PubMed     Abstract available
   
   
   
5. HULLAHALLI K, Dailey KG, Hasegawa Y, Torres E, et al
   Genetic and immune determinants of E. coli liver abscess formation.
   Proc Natl Acad Sci U S A. 2023;120:e2310053120.
   PubMed     Abstract available
   
   
   November 2023
6. YUAN D, Hu J, Ju X, Putz EM, et al
   NMDAR antagonists suppress tumor progression by regulating tumor-associated macrophages.
   Proc Natl Acad Sci U S A. 2023;120:e2302126120.
   PubMed     Abstract available
   
   
   August 2023
7. FANG LZ, Linehan V, Licursi M, Alberto CO, et al
   Prostaglandin E(2) activates melanin-concentrating hormone neurons to drive diet-induced obesity.
   Proc Natl Acad Sci U S A. 2023;120:e2302809120.
   PubMed     Abstract available
   
   
   July 2023
8. LIU B, Shen H, He J, Jin B, et al
   Cytoskeleton remodeling mediated by circRNA-YBX1 phase separation suppresses the metastasis of liver cancer.
   Proc Natl Acad Sci U S A. 2023;120:e2220296120.
   PubMed     Abstract available
   
   
   
9. GU Z, Wang L, Dong Q, Xu K, et al
   Aberrant LYZ expression in tumor cells serves as the potential biomarker and target for HCC and promotes tumor progression via csGRP78.
   Proc Natl Acad Sci U S A. 2023;120:e2215744120.
   PubMed     Abstract available
   
   
   May 2023
10. GU L, Zhu Y, Lee M, Nguyen A, et al
    Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells.
    Proc Natl Acad Sci U S A. 2023;120:e2300706120.
    PubMed     Abstract available
    
    
    
11. ZHANG J, Ning Y, Zhu H, Rotile NJ, et al
    Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T(1)-weighted MRI.
    Proc Natl Acad Sci U S A. 2023;120:e2220036120.
    PubMed     Abstract available
    
    
    April 2023
12. LONEKER AE, Alisafaei F, Kant A, Li D, et al
    Lipid droplets are intracellular mechanical stressors that impair hepatocyte function.
    Proc Natl Acad Sci U S A. 2023;120:e2216811120.
    PubMed     Abstract available
    
    
    January 2023
13. LUUKKONEN PK, Sakuma I, Gaspar RC, Mooring M, et al
    Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis.
    Proc Natl Acad Sci U S A. 2023;120:e2217543120.
    PubMed     Abstract available
    
    
    
14. QU M, Zhang G, Qu H, Vu A, et al
    Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.
    Proc Natl Acad Sci U S A. 2023;120:e2214829120.
    PubMed     Abstract available
    
    
    December 2022
15. CHEN W, Wen L, Bao Y, Tang Z, et al
    Gut flora disequilibrium promotes the initiation of liver cancer by modulating tryptophan metabolism and up-regulating SREBP2.
    Proc Natl Acad Sci U S A. 2022;119:e2203894119.
    PubMed     Abstract available
    
    
    
16. ZHAO C, Matalonga J, Lancman JJ, Liu L, et al
    Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling.
    Proc Natl Acad Sci U S A. 2022;119:e2201097119.
    PubMed     Abstract available
    
    
    November 2022
17. OSBORN LJ, Schultz K, Massey W, DeLucia B, et al
    A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis.
    Proc Natl Acad Sci U S A. 2022;119:e2202934119.
    PubMed     Abstract available
    
    
    
18. ZHOU Q, Kang G, Jiang P, Qiao R, et al
    Epigenetic analysis of cell-free DNA by fragmentomic profiling.
    Proc Natl Acad Sci U S A. 2022;119:e2209852119.
    PubMed     Abstract available
    
    
    October 2022
19. TAO Z, Cui Y, Xu X, Han T, et al
    FGFR redundancy limits the efficacy of FGFR4-selective inhibitors in hepatocellular carcinoma.
    Proc Natl Acad Sci U S A. 2022;119:e2208844119.
    PubMed     Abstract available
    
    
    September 2022
20. LIU F, Gai X, Wu Y, Zhang B, et al
    Oncogenic beta-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2202157119.
    PubMed     Abstract available
    
    
    
21. YAMADA K, Motohashi S, Oikawa T, Tago N, et al
    Extended-synaptotagmin 1 engages in unconventional protein secretion mediated via SEC22B(+) vesicle pathway in liver cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2202730119.
    PubMed     Abstract available
    
    
    August 2022
22. CHAN CY, Chiu DK, Yuen VW, Law CT, et al
    CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma.
    Proc Natl Acad Sci U S A. 2022;119:e2119514119.
    PubMed     Abstract available
    
    
    
23. KE H, Guay KP, Flotte TR, Gierasch LM, et al
    Secretion of functional alpha1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy.
    Proc Natl Acad Sci U S A. 2022;119:e2206103119.
    PubMed     Abstract available
    
    
    April 2022
24. CHENG MT, Chen Y, Chen ZP, Liu X, et al
    Structural insights into the activation of autoinhibited human lipid flippase ATP8B1 upon substrate binding.
    Proc Natl Acad Sci U S A. 2022;119:e2118656119.
    PubMed     Abstract available
    
    
    March 2022
25. KAPS L, Huppertsberg A, Choteschovsky N, Klefenz A, et al
    pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages.
    Proc Natl Acad Sci U S A. 2022;119:e2122310119.
    PubMed     Abstract available
    
    
    
26. JOUFFE C, Weger BD, Martin E, Atger F, et al
    Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
    Proc Natl Acad Sci U S A. 2022;119:e2200083119.
    PubMed     Abstract available
    
    
    January 2022
27. GAO T, Liu T, Ko CJ, Zhang L, et al
    Myeloid cell TBK1 restricts inflammatory responses.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available
    
    
    November 2021
28. VASHISTH M, Cho S, Irianto J, Xia Y, et al
    Scaling concepts in 'omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
29. HO WW, Gomes-Santos IL, Aoki S, Datta M, et al
    Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    October 2021
30. KAN X, Zhang F, Zhou G, Ji H, et al
    Interventional real-time optical imaging guidance for complete tumor ablation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
31. DENG J, Yang H, Haak VM, Yang J, et al
    Eicosanoid regulation of debris-stimulated metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    September 2021
32. LUCERO MY, Tang Y, Zhang CJ, Su S, et al
    Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson's disease and liver metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    July 2021
33. BUGIDE S, Gupta R, Green MR, Wajapeyee N, et al
    EZH2 inhibits NK cell-mediated antitumor immunity by suppressing CXCL10 expression in an HDAC10-dependent manner.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
34. NISHIO T, Koyama Y, Liu X, Rosenthal SB, et al
    Immunotherapy-based targeting of MSLN(+) activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
35. DUCIMETIERE L, Lucchiari G, Litscher G, Nater M, et al
    Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    June 2021
36. PATEL SJ, Protchenko O, Shakoury-Elizeh M, Baratz E, et al
    The iron chaperone and nucleic acid-binding activities of poly(rC)-binding protein 1 are separable and independently essential.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    April 2021
37. DARLYUK-SAADON I, Bai C, Heng CKM, Gilad N, et al
    Active p38alpha causes macrovesicular fatty liver in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    March 2021
38. SONG JS, Chang CC, Wu CH, Dinh TK, et al
    A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment.
    Proc Natl Acad Sci U S A. 2021;118:e2015433118.
    PubMed     Abstract available
    
    
    
39. MULLER K, Honcharova-Biletska H, Koppe C, Egger M, et al
    JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
40. PICCOLO P, Ferriero R, Barbato A, Attanasio S, et al
    Up-regulation of miR-34b/c by JNK and FOXO3 protects from liver fibrosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    January 2021
41. CHIBAYA L, Karim B, Zhang H, Jones SN, et al
    Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
42. WANG Q, Kim SY, Matsushita H, Wang Z, et al
    Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    

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