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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 25 articles:
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Single Articles


    November 2022
  1. OSBORN LJ, Schultz K, Massey W, DeLucia B, et al
    A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis.
    Proc Natl Acad Sci U S A. 2022;119:e2202934119.
    PubMed     Abstract available


  2. ZHOU Q, Kang G, Jiang P, Qiao R, et al
    Epigenetic analysis of cell-free DNA by fragmentomic profiling.
    Proc Natl Acad Sci U S A. 2022;119:e2209852119.
    PubMed     Abstract available


    October 2022
  3. TAO Z, Cui Y, Xu X, Han T, et al
    FGFR redundancy limits the efficacy of FGFR4-selective inhibitors in hepatocellular carcinoma.
    Proc Natl Acad Sci U S A. 2022;119:e2208844119.
    PubMed     Abstract available


    September 2022
  4. LIU F, Gai X, Wu Y, Zhang B, et al
    Oncogenic beta-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2202157119.
    PubMed     Abstract available


  5. YAMADA K, Motohashi S, Oikawa T, Tago N, et al
    Extended-synaptotagmin 1 engages in unconventional protein secretion mediated via SEC22B(+) vesicle pathway in liver cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2202730119.
    PubMed     Abstract available


    August 2022
  6. CHAN CY, Chiu DK, Yuen VW, Law CT, et al
    CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma.
    Proc Natl Acad Sci U S A. 2022;119:e2119514119.
    PubMed     Abstract available


  7. KE H, Guay KP, Flotte TR, Gierasch LM, et al
    Secretion of functional alpha1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy.
    Proc Natl Acad Sci U S A. 2022;119:e2206103119.
    PubMed     Abstract available


    April 2022
  8. CHENG MT, Chen Y, Chen ZP, Liu X, et al
    Structural insights into the activation of autoinhibited human lipid flippase ATP8B1 upon substrate binding.
    Proc Natl Acad Sci U S A. 2022;119:e2118656119.
    PubMed     Abstract available


    March 2022
  9. KAPS L, Huppertsberg A, Choteschovsky N, Klefenz A, et al
    pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages.
    Proc Natl Acad Sci U S A. 2022;119:e2122310119.
    PubMed     Abstract available


  10. JOUFFE C, Weger BD, Martin E, Atger F, et al
    Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
    Proc Natl Acad Sci U S A. 2022;119:e2200083119.
    PubMed     Abstract available


    January 2022
  11. GAO T, Liu T, Ko CJ, Zhang L, et al
    Myeloid cell TBK1 restricts inflammatory responses.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    November 2021
  12. VASHISTH M, Cho S, Irianto J, Xia Y, et al
    Scaling concepts in 'omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  13. HO WW, Gomes-Santos IL, Aoki S, Datta M, et al
    Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  14. KAN X, Zhang F, Zhou G, Ji H, et al
    Interventional real-time optical imaging guidance for complete tumor ablation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  15. DENG J, Yang H, Haak VM, Yang J, et al
    Eicosanoid regulation of debris-stimulated metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  16. LUCERO MY, Tang Y, Zhang CJ, Su S, et al
    Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson's disease and liver metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  17. BUGIDE S, Gupta R, Green MR, Wajapeyee N, et al
    EZH2 inhibits NK cell-mediated antitumor immunity by suppressing CXCL10 expression in an HDAC10-dependent manner.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  18. NISHIO T, Koyama Y, Liu X, Rosenthal SB, et al
    Immunotherapy-based targeting of MSLN(+) activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  19. DUCIMETIERE L, Lucchiari G, Litscher G, Nater M, et al
    Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  20. PATEL SJ, Protchenko O, Shakoury-Elizeh M, Baratz E, et al
    The iron chaperone and nucleic acid-binding activities of poly(rC)-binding protein 1 are separable and independently essential.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  21. DARLYUK-SAADON I, Bai C, Heng CKM, Gilad N, et al
    Active p38alpha causes macrovesicular fatty liver in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  22. MULLER K, Honcharova-Biletska H, Koppe C, Egger M, et al
    JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  23. PICCOLO P, Ferriero R, Barbato A, Attanasio S, et al
    Up-regulation of miR-34b/c by JNK and FOXO3 protects from liver fibrosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  24. CHIBAYA L, Karim B, Zhang H, Jones SN, et al
    Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  25. WANG Q, Kim SY, Matsushita H, Wang Z, et al
    Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


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