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  Hyperlipoproteinemias

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Articles published in N Engl J Med

Retrieve available abstracts of 15 articles:
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Single Articles


    November 2025
  1. LAFFIN LJ, Nicholls SJ, Scott RS, Clifton PM, et al
    Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3.
    N Engl J Med. 2025;393:2119-2130.
    PubMed     Abstract available


  2. MARSTON NA, Bergmark BA, Alexander VJ, Prohaska TA, et al
    Olezarsen for Managing Severe Hypertriglyceridemia and Pancreatitis Risk.
    N Engl J Med. 2025 Nov 8. doi: 10.1056/NEJMoa2512761.
    PubMed     Abstract available


    August 2025
  3. BERGMARK BA, Marston NA, Prohaska TA, Alexander VJ, et al
    Targeting APOC3 with Olezarsen in Moderate Hypertriglyceridemia.
    N Engl J Med. 2025 Aug 30. doi: 10.1056/NEJMoa2507227.
    PubMed     Abstract available


    July 2025
  4. MCFARLAND R, Hyslop LA, Feeney C, Pillai RN, et al
    Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease.
    N Engl J Med. 2025;393:461-468.
    PubMed     Abstract available


    May 2025
  5. NICHOLLS SJ, Nelson AJ, Ditmarsch M, Kastelein JJP, et al
    Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk.
    N Engl J Med. 2025 May 7. doi: 10.1056/NEJMoa2415820.
    PubMed     Abstract available


    March 2025
  6. MAGNUSSEN C, Alegre-Diaz J, Al-Nasser LA, Amouyel P, et al
    Global Effect of Cardiovascular Risk Factors on Lifetime Estimates.
    N Engl J Med. 2025 Mar 30. doi: 10.1056/NEJMoa2415879.
    PubMed     Abstract available


    September 2024
  7. WATTS GF, Rosenson RS, Hegele RA, Goldberg IJ, et al
    Plozasiran for Managing Persistent Chylomicronemia and Pancreatitis Risk.
    N Engl J Med. 2024 Sep 2. doi: 10.1056/NEJMoa2409368.
    PubMed     Abstract available


    August 2024
  8. FABBRINI E, Rady B, Koshkina A, Jeon JY, et al
    Phase 1 Trials of PNPLA3 siRNA in I148M Homozygous Patients with MAFLD.
    N Engl J Med. 2024;391:475-476.
    PubMed    


    May 2024
  9. ROSENSON RS, Gaudet D, Hegele RA, Ballantyne CM, et al
    Zodasiran, an RNAi Therapeutic Targeting ANGPTL3, for Mixed Hyperlipidemia.
    N Engl J Med. 2024 May 29. doi: 10.1056/NEJMoa2404147.
    PubMed     Abstract available


  10. BALLANTYNE CM, Vasas S, Azizad M, Clifton P, et al
    Plozasiran, an RNA Interference Agent Targeting APOC3, for Mixed Hyperlipidemia.
    N Engl J Med. 2024 May 28. doi: 10.1056/NEJMoa2404143.
    PubMed     Abstract available


    April 2024
  11. BERGMARK BA, Marston NA, Prohaska TA, Alexander VJ, et al
    Olezarsen for Hypertriglyceridemia in Patients at High Cardiovascular Risk.
    N Engl J Med. 2024 Apr 7. doi: 10.1056/NEJMoa2402309.
    PubMed     Abstract available


  12. WATTS GF
    Shooting the Messenger to Treat Hypertriglyceridemia.
    N Engl J Med. 2024 Apr 7. doi: 10.1056/NEJMe2402653.
    PubMed    


  13. STROES ESG, Alexander VJ, Karwatowska-Prokopczuk E, Hegele RA, et al
    Olezarsen, Acute Pancreatitis, and Familial Chylomicronemia Syndrome.
    N Engl J Med. 2024 Apr 7. doi: 10.1056/NEJMoa2400201.
    PubMed     Abstract available


    February 2024
  14. ALEXANDER VJ, Karwatowska-Prokopczuk E, Prohaska TA, Li L, et al
    Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia.
    N Engl J Med. 2024;390:476-477.
    PubMed    


    April 2023
  15. ALEXANDER JH
    Benefits of Bempedoic Acid - Clearer Now.
    N Engl J Med. 2023;388:1425-1426.
    PubMed    


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