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Lung Cancer

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 70 articles: HTML format

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March 2021
1. YANG L, Yan X, Chen J, Zhan Q, et al
   Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   December 2020
2. HOJ JP, Mayro B, Pendergast AM
   The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis.
   Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2007991117.
   PubMed     Abstract available
   
   
   
3. MAYRHOFER JE, Enzler F, Feichtner A, Rock R, et al
   Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
   Proc Natl Acad Sci U S A. 2020;117:31105-31113.
   PubMed     Abstract available
   
   
   November 2020
4. VASSEL FM, Bian K, Walker GC, Hemann MT, et al
   Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer.
   Proc Natl Acad Sci U S A. 2020 Nov 3. pii: 2016067117.
   PubMed     Abstract available
   
   
   September 2020
5. ESTEBAN-BURGOS L, Wang H, Nieto P, Zheng J, et al
   Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas.
   Proc Natl Acad Sci U S A. 2020;117:24415-24426.
   PubMed     Abstract available
   
   
   
6. YING L, Du L, Zou R, Shi L, et al
   Development of a serum miRNA panel for detection of early stage non-small cell lung cancer.
   Proc Natl Acad Sci U S A. 2020 Sep 17. pii: 2006212117.
   PubMed     Abstract available
   
   
   August 2020
7. LIU C, Xu X, Han L, Wan X, et al
   LRCH1 deficiency enhances LAT signalosome formation and CD8(+) T cell responses against tumors and pathogens.
   Proc Natl Acad Sci U S A. 2020;117:19388-19398.
   PubMed     Abstract available
   
   
   July 2020
8. SMITH HW, Yang L, Ling C, Walsh A, et al
   An ErbB2 splice variant lacking exon 16 drives lung carcinoma.
   Proc Natl Acad Sci U S A. 2020 Jul 29. pii: 2007474117.
   PubMed     Abstract available
   
   
   March 2020
9. WANG X, Yang X, Zhang C, Wang Y, et al
   Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy.
   Proc Natl Acad Sci U S A. 2020;117:6640-6650.
   PubMed     Abstract available
   
   
   
10. NA TY, Schecterson L, Mendonsa AM, Gumbiner BM, et al
    The functional activity of E-cadherin controls tumor cell metastasis at multiple steps.
    Proc Natl Acad Sci U S A. 2020;117:5931-5937.
    PubMed     Abstract available
    
    
    
11. PHILLIPS JW, Pan Y, Tsai BL, Xie Z, et al
    Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers.
    Proc Natl Acad Sci U S A. 2020;117:5269-5279.
    PubMed     Abstract available
    
    
    
12. TANG MS
    Reply to Young and Scott: Nicotine and nicotinic acetylcholine receptor mutations in electronic-cigarette smoke lung carcinogenicity.
    Proc Natl Acad Sci U S A. 2020;117:4462-4463.
    PubMed    
    
    
    
13. JIANG H, Cao HJ, Ma N, Bao WD, et al
    Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis.
    Proc Natl Acad Sci U S A. 2020;117:4770-4780.
    PubMed     Abstract available
    
    
    
14. KESAVAN R, Fromel T, Zukunft S, Laban H, et al
    Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer.
    Proc Natl Acad Sci U S A. 2020 Mar 2. pii: 1921381117.
    PubMed     Abstract available
    
    
    February 2020
15. BRANDT AC, McNally L, Lorimer EL, Unger B, et al
    Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy.
    Proc Natl Acad Sci U S A. 2020;117:3627-3636.
    PubMed     Abstract available
    
    
    
16. YOUNG RP, Scott RJ
    Inhaled nicotine and lung cancer: Potential role of the nicotinic acetylcholine receptor.
    Proc Natl Acad Sci U S A. 2020 Feb 11. pii: 1921567117.
    PubMed    
    
    
    
17. LIANG G, Meng W, Huang X, Zhu W, et al
    miR-196b-5p-mediated downregulation of TSPAN12 and GATA6 promotes tumor progression in non-small cell lung cancer.
    Proc Natl Acad Sci U S A. 2020 Feb 10. pii: 1917531117.
    PubMed     Abstract available
    
    
    
18. VITOS-FALEATO J, Real SM, Gutierrez-Prat N, Villanueva A, et al
    Requirement for epithelial p38alpha in KRAS-driven lung tumor progression.
    Proc Natl Acad Sci U S A. 2020;117:2588-2596.
    PubMed     Abstract available
    
    
    January 2020
19. NAIR P
    QnAs with Sangeeta N. Bhatia.
    Proc Natl Acad Sci U S A. 2020;117:1243-1245.
    PubMed    
    
    
    
20. NEWMAN JH, Chesson CB, Herzog NL, Bommareddy PK, et al
    Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.
    Proc Natl Acad Sci U S A. 2020;117:1119-1128.
    PubMed     Abstract available
    
    
    
21. WINKLER I, Bitter C, Winkler S, Weichenhan D, et al
    Identification of Ppargamma-modulated miRNA hubs that target the fibrotic tumor microenvironment.
    Proc Natl Acad Sci U S A. 2020;117:454-463.
    PubMed     Abstract available
    
    
    December 2019
22. NG SR, Rideout WM 3rd, Akama-Garren EH, Bhutkar A, et al
    CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer.
    Proc Natl Acad Sci U S A. 2019 Dec 23. pii: 1821893117.
    PubMed     Abstract available
    
    
    November 2019
23. LINETTE GP, Becker-Hapak M, Skidmore ZL, Baroja ML, et al
    Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens.
    Proc Natl Acad Sci U S A. 2019 Nov 4. pii: 1906026116.
    PubMed     Abstract available
    
    
    October 2019
24. LOK BH, Rudin CM
    Epigenetic targeting of DNA repair in lung cancer.
    Proc Natl Acad Sci U S A. 2019 Oct 29. pii: 1916581116.
    PubMed    
    
    
    
25. LAZARO S, Perez-Crespo M, Lorz C, Bernardini A, et al
    Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes.
    Proc Natl Acad Sci U S A. 2019 Oct 14. pii: 1821745116.
    PubMed     Abstract available
    
    
    September 2019
26. YIN Y, Xie CM, Li H, Tan M, et al
    The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells.
    Proc Natl Acad Sci U S A. 2019 Sep 23. pii: 1905973116.
    PubMed     Abstract available
    
    
    
27. LIM SB, Yeo T, Lee WD, Bhagat AAS, et al
    Addressing cellular heterogeneity in tumor and circulation for refined prognostication.
    Proc Natl Acad Sci U S A. 2019;116:17957-17962.
    PubMed     Abstract available
    
    
    August 2019
28. SCHMIDT L, Eskiocak B, Kohn R, Dang C, et al
    Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation.
    Proc Natl Acad Sci U S A. 2019;116:17460-17469.
    PubMed     Abstract available
    
    
    May 2019
29. IKEMURA S, Yasuda H, Matsumoto S, Kamada M, et al
    Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.
    Proc Natl Acad Sci U S A. 2019 May 1. pii: 1819430116.
    PubMed     Abstract available
    
    
    March 2019
30. CROW M, Lim N, Ballouz S, Pavlidis P, et al
    Predictability of human differential gene expression.
    Proc Natl Acad Sci U S A. 2019;116:6491-6500.
    PubMed     Abstract available
    
    
    February 2019
31. MONSIVAIS D, Peng J, Kang Y, Matzuk MM, et al
    Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma.
    Proc Natl Acad Sci U S A. 2019;116:3883-3892.
    PubMed     Abstract available
    
    
    
32. YAN Z, Huang N, Wu W, Chen W, et al
    Genome-wide colocalization of RNA-DNA interactions and fusion RNA pairs.
    Proc Natl Acad Sci U S A. 2019;116:3328-3337.
    PubMed     Abstract available
    
    
    
33. VILLANOVA T, Gesmundo I, Audrito V, Vitale N, et al
    Antagonists of growth hormone-releasing hormone (GHRH) inhibit the growth of human malignant pleural mesothelioma.
    Proc Natl Acad Sci U S A. 2019;116:2226-2231.
    PubMed     Abstract available
    
    
    January 2019
34. DUAH E, Teegala LR, Kondeti V, Adapala RK, et al
    Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis.
    Proc Natl Acad Sci U S A. 2019;116:199-204.
    PubMed     Abstract available
    
    
    December 2018
35. CHEN S, Giannakou A, Wyman S, Gruzas J, et al
    Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture.
    Proc Natl Acad Sci U S A. 2018;115:E11671-E11680.
    PubMed     Abstract available
    
    
    November 2018
36. SCHALLY AV, Wang H, He J, Cai R, et al
    Agonists of growth hormone-releasing hormone (GHRH) inhibit human experimental cancers in vivo by down-regulating receptors for GHRH.
    Proc Natl Acad Sci U S A. 2018;115:12028-12033.
    PubMed     Abstract available
    
    
    
37. KAWAKAMI M, Mustachio LM, Zheng L, Chen Y, et al
    Reply to Oegema et al.: CFI-400945 and Polo-like kinase 4 inhibition.
    Proc Natl Acad Sci U S A. 2018;115:E10810-E10811.
    PubMed    
    
    
    
38. OEGEMA K, Davis RL, Lara-Gonzalez P, Desai A, et al
    CFI-400945 is not a selective cellular PLK4 inhibitor.
    Proc Natl Acad Sci U S A. 2018;115:E10808-E10809.
    PubMed    
    
    
    
39. AMELIO I, Mancini M, Petrova V, Cairns RA, et al
    p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression.
    Proc Natl Acad Sci U S A. 2018;115:E10869-E10878.
    PubMed     Abstract available
    
    
    October 2018
40. SHI L, Li K, Guo Y, Banerjee A, et al
    Modulation of NKG2D, NKp46, and Ly49C/I facilitates natural killer cell-mediated control of lung cancer.
    Proc Natl Acad Sci U S A. 2018 Oct 31. pii: 1804931115.
    PubMed     Abstract available
    
    
    
41. LIANG W, Li Q, Ferrara N
    Metastatic growth instructed by neutrophil-derived transferrin.
    Proc Natl Acad Sci U S A. 2018;115:11060-11065.
    PubMed     Abstract available
    
    
    
42. KOWANETZ M, Zou W, Gettinger SN, Koeppen H, et al
    Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).
    Proc Natl Acad Sci U S A. 2018;115:E10119-E10126.
    PubMed     Abstract available
    
    
    
43. BENEJ M, Hong X, Vibhute S, Scott S, et al
    Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism.
    Proc Natl Acad Sci U S A. 2018;115:10756-10761.
    PubMed     Abstract available
    
    
    
44. XIAO GY, Mohanakrishnan A, Schmid SL
    Role for ERK1/2-dependent activation of FCHSD2 in cancer cell-selective regulation of clathrin-mediated endocytosis.
    Proc Natl Acad Sci U S A. 2018;115:E9570-E9579.
    PubMed     Abstract available
    
    
    
45. GENNARO VJ, Stanek TJ, Peck AR, Sun Y, et al
    Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells.
    Proc Natl Acad Sci U S A. 2018;115:E9298-E9307.
    PubMed     Abstract available
    
    
    September 2018
46. MORGAN MJ, Fitzwalter BE, Owens CR, Powers RK, et al
    Metastatic cells are preferentially vulnerable to lysosomal inhibition.
    Proc Natl Acad Sci U S A. 2018;115:E8479-E8488.
    PubMed     Abstract available
    
    
    August 2018
47. LI L, Li JC, Yang H, Zhang X, et al
    Expansion of cancer stem cell pool initiates lung cancer recurrence before angiogenesis.
    Proc Natl Acad Sci U S A. 2018 Aug 29. pii: 1806219115.
    PubMed     Abstract available
    
    
    July 2018
48. HOSOYA T, Sato-Kaneko F, Ahmadi A, Yao S, et al
    Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist.
    Proc Natl Acad Sci U S A. 2018;115:E6836-E6844.
    PubMed     Abstract available
    
    
    
49. WENG MW, Lee HW, Park SH, Hu Y, et al
    Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis.
    Proc Natl Acad Sci U S A. 2018;115:E6152-E6161.
    PubMed     Abstract available
    
    
    June 2018
50. FAN PD, Narzisi G, Jayaprakash AD, Venturini E, et al
    YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.
    Proc Natl Acad Sci U S A. 2018;115:E6030-E6038.
    PubMed     Abstract available
    
    
    
51. DE SEMIR D, Bezrookove V, Nosrati M, Dar AA, et al
    PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
    Proc Natl Acad Sci U S A. 2018 Jun 4. pii: 1804779115.
    PubMed     Abstract available
    
    
    May 2018
52. LEITHNER K, Triebl A, Trotzmuller M, Hinteregger B, et al
    The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
    Proc Natl Acad Sci U S A. 2018 May 29. pii: 1719871115.
    PubMed     Abstract available
    
    
    
53. WU L, Zhang H, Jiang Y, Gallo RC, et al
    Induction of antitumor cytotoxic lymphocytes using engineered human primary blood dendritic cells.
    Proc Natl Acad Sci U S A. 2018;115:E4453-E4462.
    PubMed     Abstract available
    
    
    April 2018
54. WU Q, Tian Y, Zhang J, Tong X, et al
    In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
    Proc Natl Acad Sci U S A. 2018;115:E3978-E3986.
    PubMed     Abstract available
    
    
    
55. XU H, Lee MS, Tsai PY, Adler AS, et al
    Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.
    Proc Natl Acad Sci U S A. 2018;115:4228-4233.
    PubMed     Abstract available
    
    
    
56. ZHAO L, Huang S, Mei S, Yang Z, et al
    Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.
    Proc Natl Acad Sci U S A. 2018;115:E3673-E3681.
    PubMed     Abstract available
    
    
    March 2018
57. ROBICHAUD N, Hsu BE, Istomine R, Alvarez F, et al
    Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.
    Proc Natl Acad Sci U S A. 2018;115:E2202-E2209.
    PubMed     Abstract available
    
    
    February 2018
58. 
    Correction for Goncalves et al., Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
    Proc Natl Acad Sci U S A. 2018 Feb 20. pii: 1801372115.
    PubMed    
    
    
    January 2018
59. SONG NY, Zhu F, Wang Z, Willette-Brown J, et al
    IKKalpha inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.
    Proc Natl Acad Sci U S A. 2018;115:E812-E821.
    PubMed     Abstract available
    
    
    
60. KHANDEKAR MJ, Banks AS, Laznik-Bogoslavski D, White JP, et al
    Noncanonical agonist PPARgamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy.
    Proc Natl Acad Sci U S A. 2018;115:561-566.
    PubMed     Abstract available
    
    
    
61. GONCALVES MD, Hwang SK, Pauli C, Murphy CJ, et al
    Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
    Proc Natl Acad Sci U S A. 2018 Jan 8. pii: 1714703115.
    PubMed     Abstract available
    
    
    November 2017
62. YAO K, Peng C, Zhang Y, Zykova TA, et al
    RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth.
    Proc Natl Acad Sci U S A. 2017 Nov 13. pii: 201710756.
    PubMed     Abstract available
    
    
    August 2017
63. CHANG YS, Jalgaonkar SP, Middleton JD, Hai T, et al
    Stress-inducible gene Atf3 in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Aug 7. pii: 201700455.
    PubMed     Abstract available
    
    
    June 2017
64. GOCHEVA V, Naba A, Bhutkar A, Guardia T, et al
    Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival.
    Proc Natl Acad Sci U S A. 2017 Jun 26. pii: 201707054.
    PubMed     Abstract available
    
    
    April 2017
65. KAMPHORST AO, Pillai RN, Yang S, Nasti TH, et al
    Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients.
    Proc Natl Acad Sci U S A. 2017 Apr 26. pii: 201705327.
    PubMed     Abstract available
    
    
    
66. 
    Editorial Expression of Concern: WWOX gene restoration prevents lung cancer growth in vitro and in vivo.
    Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201704296.
    PubMed    
    
    
    March 2017
67. 
    Correction for Tang et al., High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.
    Proc Natl Acad Sci U S A. 2017 Mar 27. pii: 201703650.
    PubMed    
    
    
    
68. MOU H, Moore J, Malonia SK, Li Y, et al
    Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis.
    Proc Natl Acad Sci U S A. 2017 Mar 20. pii: 201620861.
    PubMed     Abstract available
    
    
    January 2017
69. TUNG B, Schade B, Cardiff RD, Aina OH, et al
    beta-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201610383.
    PubMed     Abstract available
    
    
    
70. CHEN P, Zuo H, Xiong H, Kolar MJ, et al
    Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Jan 3. pii: 201614035.
    PubMed     Abstract available
    
    

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