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COVID-19: Daily Top 10 Papers


  Lung Cancer

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Articles published in Proc Natl Acad Sci U S A

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    December 2021
  1. SCHULT TA, Lauer MJ, Berker Y, Cardoso MR, et al
    Screening human lung cancer with predictive models of serum magnetic resonance spectroscopy metabolomics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  2. ZHAO X, Hu J, Li Y, Guo M, et al
    Volumetric compression develops noise-driven single-cell heterogeneity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  3. CHEON H, Holvey-Bates EG, McGrail DJ, Stark GR, et al
    PD-L1 sustains chronic, cancer cell-intrinsic responses to type I interferon, enhancing resistance to DNA damage.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  4. DE S, Holvey-Bates EG, Mahen K, Willard B, et al
    The ubiquitin E3 ligase FBXO22 degrades PD-L1 and sensitizes cancer cells to DNA damage.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  5. LLABATA P, Torres-Diz M, Gomez A, Tomas-Daza L, et al
    MAX mutant small-cell lung cancers exhibit impaired activities of MGA-dependent noncanonical polycomb repressive complex.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  6. Correction for Jeon et al., A set of NF-kappaB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    August 2021
  7. MUELLER HS, Fowler CE, Dalin S, Moiso E, et al
    Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  8. SALMON M, Paniagua G, Lechuga CG, Fernandez-Garcia F, et al
    KRAS4A induces metastatic lung adenocarcinomas in vivo in the absence of the KRAS4B isoform.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  9. LIU Z, Wang F, Liu X, Sang Y, et al
    Cell membrane-camouflaged liposomes for tumor cell-selective glycans engineering and imaging in vivo.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  10. ETXEBERRIA I, Bolanos E, Teijeira A, Garasa S, et al
    Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  11. SHI L, Tan X, Liu X, Yu J, et al
    Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  12. SANCHEZ-RIVERA FJ, Ryan J, Soto-Feliciano YM, Clare Beytagh M, et al
    Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  13. PRADHAN AK, Maji S, Bhoopathi P, Talukdar S, et al
    Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1beta.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  14. DING Y, Liu Y, Lee DK, Tong Z, et al
    Cell lineage tracing links ERalpha loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  15. TIEN JC, Chugh S, Goodrum AE, Cheng Y, et al
    AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  16. WANG R, Godet I, Yang Y, Salman S, et al
    Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  17. TILSTON-LUNEL A, Mazzilli S, Kingston NM, Szymaniak AD, et al
    Aberrant epithelial polarity cues drive the development of precancerous airway lesions.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  18. WAN PK, Tong KC, Lok CN, Zhang C, et al
    Platinum(II) N-heterocyclic carbene complexes arrest metastatic tumor growth.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  19. YANG L, Yan X, Chen J, Zhan Q, et al
    Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  20. BROWNLIE D, Scharenberg M, Mold JE, Hard J, et al
    Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  21. JIMENEZ-SANCHEZ J, Bosque JJ, Jimenez Londono GA, Molina-Garcia D, et al
    Evolutionary dynamics at the tumor edge reveal metabolic imaging biomarkers.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  22. CHIBAYA L, Karim B, Zhang H, Jones SN, et al
    Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  23. XIAO Y, Lin FT, Lin WC
    ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  24. HOJ JP, Mayro B, Pendergast AM
    The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2007991117.
    PubMed     Abstract available


  25. MAYRHOFER JE, Enzler F, Feichtner A, Rock R, et al
    Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
    Proc Natl Acad Sci U S A. 2020;117:31105-31113.
    PubMed     Abstract available


    November 2020
  26. VASSEL FM, Bian K, Walker GC, Hemann MT, et al
    Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer.
    Proc Natl Acad Sci U S A. 2020 Nov 3. pii: 2016067117.
    PubMed     Abstract available


    September 2020
  27. ESTEBAN-BURGOS L, Wang H, Nieto P, Zheng J, et al
    Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas.
    Proc Natl Acad Sci U S A. 2020;117:24415-24426.
    PubMed     Abstract available


  28. YING L, Du L, Zou R, Shi L, et al
    Development of a serum miRNA panel for detection of early stage non-small cell lung cancer.
    Proc Natl Acad Sci U S A. 2020 Sep 17. pii: 2006212117.
    PubMed     Abstract available


    August 2020
  29. LIU C, Xu X, Han L, Wan X, et al
    LRCH1 deficiency enhances LAT signalosome formation and CD8(+) T cell responses against tumors and pathogens.
    Proc Natl Acad Sci U S A. 2020;117:19388-19398.
    PubMed     Abstract available


    July 2020
  30. SMITH HW, Yang L, Ling C, Walsh A, et al
    An ErbB2 splice variant lacking exon 16 drives lung carcinoma.
    Proc Natl Acad Sci U S A. 2020 Jul 29. pii: 2007474117.
    PubMed     Abstract available


    March 2020
  31. WANG X, Yang X, Zhang C, Wang Y, et al
    Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy.
    Proc Natl Acad Sci U S A. 2020;117:6640-6650.
    PubMed     Abstract available


  32. NA TY, Schecterson L, Mendonsa AM, Gumbiner BM, et al
    The functional activity of E-cadherin controls tumor cell metastasis at multiple steps.
    Proc Natl Acad Sci U S A. 2020;117:5931-5937.
    PubMed     Abstract available


  33. PHILLIPS JW, Pan Y, Tsai BL, Xie Z, et al
    Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers.
    Proc Natl Acad Sci U S A. 2020;117:5269-5279.
    PubMed     Abstract available


  34. TANG MS
    Reply to Young and Scott: Nicotine and nicotinic acetylcholine receptor mutations in electronic-cigarette smoke lung carcinogenicity.
    Proc Natl Acad Sci U S A. 2020;117:4462-4463.
    PubMed    


  35. JIANG H, Cao HJ, Ma N, Bao WD, et al
    Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis.
    Proc Natl Acad Sci U S A. 2020;117:4770-4780.
    PubMed     Abstract available


  36. KESAVAN R, Fromel T, Zukunft S, Laban H, et al
    Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer.
    Proc Natl Acad Sci U S A. 2020 Mar 2. pii: 1921381117.
    PubMed     Abstract available


    February 2020
  37. BRANDT AC, McNally L, Lorimer EL, Unger B, et al
    Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy.
    Proc Natl Acad Sci U S A. 2020;117:3627-3636.
    PubMed     Abstract available


  38. VITOS-FALEATO J, Real SM, Gutierrez-Prat N, Villanueva A, et al
    Requirement for epithelial p38alpha in KRAS-driven lung tumor progression.
    Proc Natl Acad Sci U S A. 2020;117:2588-2596.
    PubMed     Abstract available


    January 2020
  39. NAIR P
    QnAs with Sangeeta N. Bhatia.
    Proc Natl Acad Sci U S A. 2020;117:1243-1245.
    PubMed    


  40. NEWMAN JH, Chesson CB, Herzog NL, Bommareddy PK, et al
    Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.
    Proc Natl Acad Sci U S A. 2020;117:1119-1128.
    PubMed     Abstract available


  41. WINKLER I, Bitter C, Winkler S, Weichenhan D, et al
    Identification of Ppargamma-modulated miRNA hubs that target the fibrotic tumor microenvironment.
    Proc Natl Acad Sci U S A. 2020;117:454-463.
    PubMed     Abstract available


    November 2019
  42. LINETTE GP, Becker-Hapak M, Skidmore ZL, Baroja ML, et al
    Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens.
    Proc Natl Acad Sci U S A. 2019 Nov 4. pii: 1906026116.
    PubMed     Abstract available


    September 2019
  43. YIN Y, Xie CM, Li H, Tan M, et al
    The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells.
    Proc Natl Acad Sci U S A. 2019 Sep 23. pii: 1905973116.
    PubMed     Abstract available


  44. LIM SB, Yeo T, Lee WD, Bhagat AAS, et al
    Addressing cellular heterogeneity in tumor and circulation for refined prognostication.
    Proc Natl Acad Sci U S A. 2019;116:17957-17962.
    PubMed     Abstract available


    August 2019
  45. SCHMIDT L, Eskiocak B, Kohn R, Dang C, et al
    Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation.
    Proc Natl Acad Sci U S A. 2019;116:17460-17469.
    PubMed     Abstract available


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