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Articles published in Proc Natl Acad Sci U S A

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    December 2018
  1. CHEN S, Giannakou A, Wyman S, Gruzas J, et al
    Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture.
    Proc Natl Acad Sci U S A. 2018;115:E11671-E11680.
    PubMed     Text format     Abstract available


    November 2018
  2. SCHALLY AV, Wang H, He J, Cai R, et al
    Agonists of growth hormone-releasing hormone (GHRH) inhibit human experimental cancers in vivo by down-regulating receptors for GHRH.
    Proc Natl Acad Sci U S A. 2018;115:12028-12033.
    PubMed     Text format     Abstract available


  3. KAWAKAMI M, Mustachio LM, Zheng L, Chen Y, et al
    Reply to Oegema et al.: CFI-400945 and Polo-like kinase 4 inhibition.
    Proc Natl Acad Sci U S A. 2018;115:E10810-E10811.
    PubMed     Text format    


  4. OEGEMA K, Davis RL, Lara-Gonzalez P, Desai A, et al
    CFI-400945 is not a selective cellular PLK4 inhibitor.
    Proc Natl Acad Sci U S A. 2018;115:E10808-E10809.
    PubMed     Text format    


  5. AMELIO I, Mancini M, Petrova V, Cairns RA, et al
    p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression.
    Proc Natl Acad Sci U S A. 2018;115:E10869-E10878.
    PubMed     Text format     Abstract available


    October 2018
  6. SHI L, Li K, Guo Y, Banerjee A, et al
    Modulation of NKG2D, NKp46, and Ly49C/I facilitates natural killer cell-mediated control of lung cancer.
    Proc Natl Acad Sci U S A. 2018 Oct 31. pii: 1804931115.
    PubMed     Text format     Abstract available


  7. LIANG W, Li Q, Ferrara N
    Metastatic growth instructed by neutrophil-derived transferrin.
    Proc Natl Acad Sci U S A. 2018;115:11060-11065.
    PubMed     Text format     Abstract available


  8. KOWANETZ M, Zou W, Gettinger SN, Koeppen H, et al
    Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).
    Proc Natl Acad Sci U S A. 2018;115:E10119-E10126.
    PubMed     Text format     Abstract available


  9. BENEJ M, Hong X, Vibhute S, Scott S, et al
    Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism.
    Proc Natl Acad Sci U S A. 2018;115:10756-10761.
    PubMed     Text format     Abstract available


  10. XIAO GY, Mohanakrishnan A, Schmid SL
    Role for ERK1/2-dependent activation of FCHSD2 in cancer cell-selective regulation of clathrin-mediated endocytosis.
    Proc Natl Acad Sci U S A. 2018;115:E9570-E9579.
    PubMed     Text format     Abstract available


  11. GENNARO VJ, Stanek TJ, Peck AR, Sun Y, et al
    Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells.
    Proc Natl Acad Sci U S A. 2018;115:E9298-E9307.
    PubMed     Text format     Abstract available


    September 2018
  12. MORGAN MJ, Fitzwalter BE, Owens CR, Powers RK, et al
    Metastatic cells are preferentially vulnerable to lysosomal inhibition.
    Proc Natl Acad Sci U S A. 2018;115:E8479-E8488.
    PubMed     Text format     Abstract available


    August 2018
  13. LI L, Li JC, Yang H, Zhang X, et al
    Expansion of cancer stem cell pool initiates lung cancer recurrence before angiogenesis.
    Proc Natl Acad Sci U S A. 2018 Aug 29. pii: 1806219115.
    PubMed     Text format     Abstract available


    July 2018
  14. HOSOYA T, Sato-Kaneko F, Ahmadi A, Yao S, et al
    Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist.
    Proc Natl Acad Sci U S A. 2018;115:E6836-E6844.
    PubMed     Text format     Abstract available


  15. WENG MW, Lee HW, Park SH, Hu Y, et al
    Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis.
    Proc Natl Acad Sci U S A. 2018;115:E6152-E6161.
    PubMed     Text format     Abstract available


    June 2018
  16. FAN PD, Narzisi G, Jayaprakash AD, Venturini E, et al
    YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.
    Proc Natl Acad Sci U S A. 2018;115:E6030-E6038.
    PubMed     Text format     Abstract available


  17. DE SEMIR D, Bezrookove V, Nosrati M, Dar AA, et al
    PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
    Proc Natl Acad Sci U S A. 2018 Jun 4. pii: 1804779115.
    PubMed     Text format     Abstract available


    May 2018
  18. LEITHNER K, Triebl A, Trotzmuller M, Hinteregger B, et al
    The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
    Proc Natl Acad Sci U S A. 2018 May 29. pii: 1719871115.
    PubMed     Text format     Abstract available


  19. WU L, Zhang H, Jiang Y, Gallo RC, et al
    Induction of antitumor cytotoxic lymphocytes using engineered human primary blood dendritic cells.
    Proc Natl Acad Sci U S A. 2018;115:E4453-E4462.
    PubMed     Text format     Abstract available


    April 2018
  20. WU Q, Tian Y, Zhang J, Tong X, et al
    In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
    Proc Natl Acad Sci U S A. 2018;115:E3978-E3986.
    PubMed     Text format     Abstract available


  21. XU H, Lee MS, Tsai PY, Adler AS, et al
    Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.
    Proc Natl Acad Sci U S A. 2018;115:4228-4233.
    PubMed     Text format     Abstract available


  22. ZHAO L, Huang S, Mei S, Yang Z, et al
    Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.
    Proc Natl Acad Sci U S A. 2018;115:E3673-E3681.
    PubMed     Text format     Abstract available


    March 2018
  23. ROBICHAUD N, Hsu BE, Istomine R, Alvarez F, et al
    Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.
    Proc Natl Acad Sci U S A. 2018;115:E2202-E2209.
    PubMed     Text format     Abstract available


    February 2018

  24. Correction for Goncalves et al., Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
    Proc Natl Acad Sci U S A. 2018 Feb 20. pii: 1801372115.
    PubMed     Text format    


    January 2018
  25. SONG NY, Zhu F, Wang Z, Willette-Brown J, et al
    IKKalpha inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.
    Proc Natl Acad Sci U S A. 2018;115:E812-E821.
    PubMed     Text format     Abstract available


  26. KHANDEKAR MJ, Banks AS, Laznik-Bogoslavski D, White JP, et al
    Noncanonical agonist PPARgamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy.
    Proc Natl Acad Sci U S A. 2018;115:561-566.
    PubMed     Text format     Abstract available


  27. GONCALVES MD, Hwang SK, Pauli C, Murphy CJ, et al
    Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
    Proc Natl Acad Sci U S A. 2018 Jan 8. pii: 1714703115.
    PubMed     Text format     Abstract available


    November 2017
  28. YAO K, Peng C, Zhang Y, Zykova TA, et al
    RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth.
    Proc Natl Acad Sci U S A. 2017 Nov 13. pii: 201710756.
    PubMed     Text format     Abstract available


    August 2017
  29. CHANG YS, Jalgaonkar SP, Middleton JD, Hai T, et al
    Stress-inducible gene Atf3 in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Aug 7. pii: 201700455.
    PubMed     Text format     Abstract available


    June 2017
  30. GOCHEVA V, Naba A, Bhutkar A, Guardia T, et al
    Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival.
    Proc Natl Acad Sci U S A. 2017 Jun 26. pii: 201707054.
    PubMed     Text format     Abstract available


    April 2017
  31. KAMPHORST AO, Pillai RN, Yang S, Nasti TH, et al
    Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients.
    Proc Natl Acad Sci U S A. 2017 Apr 26. pii: 201705327.
    PubMed     Text format     Abstract available



  32. Editorial Expression of Concern: WWOX gene restoration prevents lung cancer growth in vitro and in vivo.
    Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201704296.
    PubMed     Text format    


    March 2017

  33. Correction for Tang et al., High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.
    Proc Natl Acad Sci U S A. 2017 Mar 27. pii: 201703650.
    PubMed     Text format    


  34. MOU H, Moore J, Malonia SK, Li Y, et al
    Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis.
    Proc Natl Acad Sci U S A. 2017 Mar 20. pii: 201620861.
    PubMed     Text format     Abstract available


    January 2017
  35. TUNG B, Schade B, Cardiff RD, Aina OH, et al
    beta-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201610383.
    PubMed     Text format     Abstract available


  36. CHEN P, Zuo H, Xiong H, Kolar MJ, et al
    Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Jan 3. pii: 201614035.
    PubMed     Text format     Abstract available


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