Retrieve available abstracts of 37 articles: HTML format
Single Articles
June 2025
WANG M, Wang Y, Pan X, Wang B, et al Acquired resistance to immunotherapy by physical barriers with cancer
cell-expressing collagens in non-small cell lung cancer.
Proc Natl Acad Sci U S A. 2025;122:e2500019122. PubMedAbstract available
GORELIK A, Paulo JA, Schroeter CB, Lad M, et al CRISPR screens and quantitative proteomics reveal remodeling of the aryl
hydrocarbon receptor-driven proteome through PARP7 activity.
Proc Natl Acad Sci U S A. 2025;122:e2424985122. PubMedAbstract available
May 2025
WANG H, Huang J, Zhang Z, An Y, et al Phase separation of RXRgamma drives tumor chemoresistance and represents a
therapeutic target for small-cell lung cancer.
Proc Natl Acad Sci U S A. 2025;122:e2421199122. PubMedAbstract available
JIAO Z, Zhang M, Ning J, Yao H, et al The oncoprotein SET promotes serine-derived one-carbon metabolism by regulating
SHMT2 enzymatic activity.
Proc Natl Acad Sci U S A. 2025;122:e2412854122. PubMedAbstract available
April 2025
GONG JR, Lee J, Han Y, Cho KH, et al DDX54 downregulation enhances anti-PD1 therapy in immune-desert lung tumors with
high tumor mutational burden.
Proc Natl Acad Sci U S A. 2025;122:e2412310122. PubMedAbstract available
YIN L, Zhang J, Zhu Z, Peng X, et al The FBXW7-KMT2 axis in cancer-associated fibroblasts controls tumor growth via an
epigenetic-paracrine mechanism.
Proc Natl Acad Sci U S A. 2025;122:e2423130122. PubMedAbstract available
March 2025
BALTANAS FC, Kramer-Drauberg M, Garcia-Navas R, Patrucco E, et al SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation
and synergizes with a KRAS(G12D) inhibitor in KRAS LUAD.
Proc Natl Acad Sci U S A. 2025;122:e2422943122. PubMedAbstract available
SAXENA T, Quan A, Chan E, Kozlova N, et al EGFR-induced lncRNA TRIDENT promotes drug resistance in non-small cell lung
cancer via phospho-TRIM28-mediated DNA damage repair.
Proc Natl Acad Sci U S A. 2025;122:e2415389122. PubMedAbstract available
January 2025
ZHANG Y, Wang X, Gu Y, Liu T, et al Complement C3 of tumor-derived extracellular vesicles promotes metastasis of RCC
via recruitment of immunosuppressive myeloid cells.
Proc Natl Acad Sci U S A. 2025;122:e2420005122. PubMedAbstract available
December 2024
MEI J, Jiang J, Li Z, Pan Y, et al Increased perfluorooctanoic acid accumulation facilitates the migration and
invasion of lung cancer cells via remodeling cell mechanics.
Proc Natl Acad Sci U S A. 2024;121:e2408575121. PubMedAbstract available
CHEN J, Wang T, Zhang D, Wang H, et al KDM5D histone demethylase mediates p38alpha inactivation via its enzymatic activity
to inhibit cancer progression.
Proc Natl Acad Sci U S A. 2024;121:e2402022121. PubMedAbstract available
November 2024
ZHAO H, Beyett TS, Jiang J, Rana JK, et al Biochemical analysis of EGFR exon20 insertion variants insASV and insSVD and
their inhibitor sensitivity.
Proc Natl Acad Sci U S A. 2024;121:e2417144121. PubMedAbstract available
October 2024
ZHU J, Du W, Zeng Y, Liu T, et al CD73 promotes non-small cell lung cancer metastasis by regulating Axl signaling
independent of GAS6.
Proc Natl Acad Sci U S A. 2024;121:e2404709121. PubMedAbstract available
MCGUIRE CK, Meehan AS, Couser E, Bull L, et al Transcriptional repression by HDAC3 mediates T cell exclusion from Kras mutant
lung tumors.
Proc Natl Acad Sci U S A. 2024;121:e2317694121. PubMedAbstract available
DAVIS E, Avniel-Polak S, Abu-Kamel S, Antman I, et al Enhancer landscape of lung neuroendocrine tumors reveals regulatory and
developmental signatures with potential theranostic implications.
Proc Natl Acad Sci U S A. 2024;121:e2405001121. PubMedAbstract available
September 2024
FUJIWARA Y, Takahashi RU, Saito M, Umakoshi M, et al Oncofetal IGF2BP3-mediated control of microRNA structural diversity in the
malignancy of early-stage lung adenocarcinoma.
Proc Natl Acad Sci U S A. 2024;121:e2407016121. PubMedAbstract available
FERNANDEZ-GARCIA F, Fernandez-Rodriguez A, Fustero-Torre C, Pineiro-Yanez E, et al Type I interferon signaling pathway enhances immune-checkpoint inhibition in KRAS
mutant lung tumors.
Proc Natl Acad Sci U S A. 2024;121:e2402913121. PubMedAbstract available
July 2024
SHAN L, Wang W, Du L, Li D, et al SP1 undergoes phase separation and activates RGS20 expression through
super-enhancers to promote lung adenocarcinoma progression.
Proc Natl Acad Sci U S A. 2024;121:e2401834121. PubMedAbstract available
LARA-SAEZ I, Mencia A, Recuero E, Li Y, et al Nonviral CRISPR/Cas9 mutagenesis for streamlined generation of mouse lung cancer
models.
Proc Natl Acad Sci U S A. 2024;121:e2322917121. PubMedAbstract available
June 2024
KUMARI P, Tarighi S, Fuchshuber E, Li L, et al SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF.
Proc Natl Acad Sci U S A. 2024;121:e2409269121. PubMedAbstract available
RUAN ML, Ni WX, Chu JCH, Lam TL, et al Iridium(III) carbene complexes as potent girdin inhibitors against metastatic
cancers.
Proc Natl Acad Sci U S A. 2024;121:e2316615121. PubMedAbstract available
YANG C, Ma S, Zhang J, Han Y, et al EHMT2-mediated transcriptional reprogramming drives neuroendocrine transformation
in non-small cell lung cancer.
Proc Natl Acad Sci U S A. 2024;121:e2317790121. PubMedAbstract available
May 2024
FERRARONE JR, Thomas J, Unni AM, Zheng Y, et al Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor
LKB1 inhibits growth via the PIKFYVE lipid kinase.
Proc Natl Acad Sci U S A. 2024;121:e2403685121. PubMedAbstract available
DONG Z, Wang Y, Xu G, Liu B, et al Genetic and phenotypic profiling of single living circulating tumor cells from
patients with microfluidics.
Proc Natl Acad Sci U S A. 2024;121:e2315168121. PubMedAbstract available
DUTT P, Haider N, Mouaaz S, Podmore L, et al beta-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in
A549 lung adenocarcinoma cells.
Proc Natl Acad Sci U S A. 2024;121:e2300606121. PubMedAbstract available
March 2024
HAN X, Wang D, Yang L, Wang N, et al Activation of polyamine catabolism promotes glutamine metabolism and creates a
targetable vulnerability in lung cancer.
Proc Natl Acad Sci U S A. 2024;121:e2319429121. PubMedAbstract available
February 2024
JANSEN RA, Mainardi S, Dias MH, Bosma A, et al Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in
KRAS-mutant cancers.
Proc Natl Acad Sci U S A. 2024;121:e2319492121. PubMedAbstract available
January 2024
CHEN NY, Lin CW, Lai TY, Wu CY, et al Increased expression of SSEA-4 on TKI-resistant non-small cell lung cancer with
EGFR-T790M mutation.
Proc Natl Acad Sci U S A. 2024;121:e2313397121. PubMedAbstract available
WU XN, Li JY, He Q, Li BQ, et al Targeting the PHF8/YY1 axis suppresses cancer cell growth through modulation of
ROS.
Proc Natl Acad Sci U S A. 2024;121:e2219352120. PubMedAbstract available
December 2023
LEE H, Jung JH, Ko HM, Park H, et al RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal
proteins uL18 and uL5.
Proc Natl Acad Sci U S A. 2023;120:e2308292120. PubMedAbstract available
October 2023
CHUNG YH, Ortega-Rivera OA, Volckaert BA, Jung E, et al Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and
metastasis.
Proc Natl Acad Sci U S A. 2023;120:e2221859120. PubMedAbstract available
IM SJ, Obeng RC, Nasti TH, McManus D, et al Characteristics and anatomic location of PD-1(+)TCF1(+) stem-like CD8 T cells in
chronic viral infection and cancer.
Proc Natl Acad Sci U S A. 2023;120:e2221985120. PubMedAbstract available
GINN L, Maltas J, Baker MJ, Chaturvedi A, et al A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote
migration of lung cancer cells.
Proc Natl Acad Sci U S A. 2023;120:e2300489120. PubMedAbstract available
September 2023
SUAREZ JS, Novelli F, Goto K, Ehara M, et al HMGB1 released by mesothelial cells drives the development of asbestos-induced
mesothelioma.
Proc Natl Acad Sci U S A. 2023;120:e2307999120. PubMedAbstract available
CHEN Y, Shi J, Wang X, Zhou L, et al An antioxidant feedforward cycle coordinated by linker histone variant H1.2 and
NRF2 that drives nonsmall cell lung cancer progression.
Proc Natl Acad Sci U S A. 2023;120:e2306288120. PubMedAbstract available
LIN X, Chen Y, Lin L, Yin K, et al mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing
of pooled single-cell RNA-seq.
Proc Natl Acad Sci U S A. 2023;120:e2307722120. PubMedAbstract available
YOUSEFI M, Andrejka L, Szamecz M, Winslow MM, et al Fully accessible fitness landscape of oncogene-negative lung adenocarcinoma.
Proc Natl Acad Sci U S A. 2023;120:e2303224120. PubMedAbstract available