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Articles published in Proc Natl Acad Sci U S A

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    July 2018
  1. CHENG C, Tan JC, Hahn MW, Besansky NJ, et al
    Systems genetic analysis of inversion polymorphisms in the malaria mosquito Anopheles gambiae.
    Proc Natl Acad Sci U S A. 2018 Jul 9. pii: 1806760115.
    PubMed     Text format     Abstract available


    June 2018
  2. STRANGWARD P, Haley MJ, Albornoz MG, Barrington J, et al
    Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria.
    Proc Natl Acad Sci U S A. 2018 Jun 28. pii: 1801737115.
    PubMed     Text format     Abstract available


    May 2018
  3. HANCOCK PA, Wiebe A, Gleave KA, Bhatt S, et al
    Associated patterns of insecticide resistance in field populations of malaria vectors across Africa.
    Proc Natl Acad Sci U S A. 2018 May 21. pii: 1801826115.
    PubMed     Text format     Abstract available


  4. DE MORAES CM, Wanjiku C, Stanczyk NM, Pulido H, et al
    Volatile biomarkers of symptomatic and asymptomatic malaria infection in humans.
    Proc Natl Acad Sci U S A. 2018 May 14. pii: 1801512115.
    PubMed     Text format     Abstract available


    April 2018
  5. VONTAS J, Grigoraki L, Morgan J, Tsakireli D, et al
    Rapid selection of a pyrethroid metabolic enzyme CYP9K1 by operational malaria control activities.
    Proc Natl Acad Sci U S A. 2018 Apr 19. pii: 1719663115.
    PubMed     Text format     Abstract available


    February 2018
  6. DELLIBOVI-RAGHEB TA, Jhun H, Goodman CD, Walters MS, et al
    Host biotin is required for liver stage development in malaria parasites.
    Proc Natl Acad Sci U S A. 2018 Feb 26. pii: 1800717115.
    PubMed     Text format     Abstract available


  7. LANGLAIS D, Cencic R, Moradin N, Kennedy JM, et al
    Rocaglates as dual-targeting agents for experimental cerebral malaria.
    Proc Natl Acad Sci U S A. 2018 Feb 20. pii: 1713000115.
    PubMed     Text format     Abstract available


    January 2018
  8. AZASI Y, Lindergard G, Ghumra A, Mu J, et al
    Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function.
    Proc Natl Acad Sci U S A. 2018;115:1063-1068.
    PubMed     Text format     Abstract available


  9. BANSAL A, Molina-Cruz A, Brzostowski J, Liu P, et al
    PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection.
    Proc Natl Acad Sci U S A. 2018 Jan 8. pii: 1715443115.
    PubMed     Text format     Abstract available


    December 2017
  10. KAFY HT, Ismail BA, Mnzava AP, Lines J, et al
    Impact of insecticide resistance in Anopheles arabiensis on malaria incidence and prevalence in Sudan and the costs of mitigation.
    Proc Natl Acad Sci U S A. 2017 Dec 11. pii: 1713814114.
    PubMed     Text format     Abstract available


    November 2017
  11. GOTZ A, Tang MS, Ty MC, Arama C, et al
    Atypical activation of dendritic cells by Plasmodium falciparum.
    Proc Natl Acad Sci U S A. 2017 Nov 21. pii: 201708383.
    PubMed     Text format     Abstract available


  12. OYEN D, Torres JL, Wille-Reece U, Ockenhouse CF, et al
    Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein.
    Proc Natl Acad Sci U S A. 2017 Nov 14. pii: 201715812.
    PubMed     Text format     Abstract available


  13. GOMES FM, Hixson BL, Tyner MDW, Ramirez JL, et al
    Effect of naturally occurring Wolbachia in Anopheles gambiae s.l. mosquitoes from Mali on Plasmodium falciparum malaria transmission.
    Proc Natl Acad Sci U S A. 2017 Nov 7. pii: 201716181.
    PubMed     Text format     Abstract available


    October 2017
  14. KANJEE U, Gruring C, Chaand M, Lin KM, et al
    CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion.
    Proc Natl Acad Sci U S A. 2017;114:E9356-E9365.
    PubMed     Text format     Abstract available


  15. BUSTAMANTE LY, Powell GT, Lin YC, Macklin MD, et al
    Synergistic malaria vaccine combinations identified by systematic antigen screening.
    Proc Natl Acad Sci U S A. 2017 Oct 23. pii: 201702944.
    PubMed     Text format     Abstract available


    September 2017
  16. POSPICH S, Kumpula EP, von der Ecken J, Vahokoski J, et al
    Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.
    Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201707506.
    PubMed     Text format     Abstract available


    July 2017
  17. SULLIVAN DJ JR
    Quinolines block every step of malaria heme crystal growth.
    Proc Natl Acad Sci U S A. 2017 Jul 10. pii: 201708153.
    PubMed     Text format    


    May 2017
  18. DAY KP, Artzy-Randrup Y, Tiedje KE, Rougeron V, et al
    Evidence of strain structure in Plasmodium falciparum var gene repertoires in children from Gabon, West Africa.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201613018.
    PubMed     Text format     Abstract available


    April 2017
  19. KOCH M, Wright KE, Otto O, Herbig M, et al
    Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion.
    Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201620843.
    PubMed     Text format     Abstract available


    March 2017
  20. HALE VL, Watermeyer JM, Hackett F, Vizcay-Barrena G, et al
    Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress.
    Proc Natl Acad Sci U S A. 2017 Mar 14. pii: 201619441.
    PubMed     Text format     Abstract available


  21. ATAIDE R, Ashley EA, Powell R, Chan JA, et al
    Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort.
    Proc Natl Acad Sci U S A. 2017 Mar 13. pii: 201615875.
    PubMed     Text format     Abstract available


    February 2017
  22. ABSHIRE JR, Rowlands CJ, Ganesan SM, So PT, et al
    Quantification of labile heme in live malaria parasites using a genetically encoded biosensor.
    Proc Natl Acad Sci U S A. 2017 Feb 27. pii: 201615195.
    PubMed     Text format     Abstract available


  23. LYKE KE, Ishizuka AS, Berry AA, Chakravarty S, et al
    Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection.
    Proc Natl Acad Sci U S A. 2017 Feb 21. pii: 201615324.
    PubMed     Text format     Abstract available


  24. KAZMIN D, Nakaya HI, Lee EK, Johnson MJ, et al
    Systems analysis of protective immune responses to RTS,S malaria vaccination in humans.
    Proc Natl Acad Sci U S A. 2017 Feb 13. pii: 201621489.
    PubMed     Text format     Abstract available


    January 2017
  25. CAMPEOTTO I, Goldenzweig A, Davey J, Barfod L, et al
    One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201616903.
    PubMed     Text format     Abstract available


    December 2016
  26. ECKHOFF PA, Wenger EA, Godfray HC, Burt A, et al
    Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics.
    Proc Natl Acad Sci U S A. 2016 Dec 27. pii: 201611064.
    PubMed     Text format     Abstract available


  27. BARNES KG, Irving H, Chiumia M, Mzilahowa T, et al
    Restriction to gene flow is associated with changes in the molecular basis of pyrethroid resistance in the malaria vector Anopheles funestus.
    Proc Natl Acad Sci U S A. 2016 Dec 21. pii: 201615458.
    PubMed     Text format     Abstract available


    November 2016
  28. PAROBEK CM, Lin JT, Saunders DL, Barnett EJ, et al
    Selective sweep suggests transcriptional regulation may underlie Plasmodium vivax resilience to malaria control measures in Cambodia.
    Proc Natl Acad Sci U S A. 2016 Nov 28. pii: 201608828.
    PubMed     Text format     Abstract available


    August 2016
  29. THOMAS MB, Read AF
    The threat (or not) of insecticide resistance for malaria control.
    Proc Natl Acad Sci U S A. 2016 Aug 1. pii: 201609889.
    PubMed     Text format    


    July 2016
  30. VIANA M, Hughes A, Matthiopoulos J, Ranson H, et al
    Delayed mortality effects cut the malaria transmission potential of insecticide-resistant mosquitoes.
    Proc Natl Acad Sci U S A. 2016 Jul 11. pii: 201603431.
    PubMed     Text format     Abstract available


    June 2016
  31. LELLIOTT PM, Coban C
    IFN-gamma protects hepatocytes against Plasmodium vivax infection via LAP-like degradation of sporozoites.
    Proc Natl Acad Sci U S A. 2016;113:6813-5.
    PubMed     Text format    


  32. MOON RW, Sharaf H, Hastings CH, Ho YS, et al
    Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi.
    Proc Natl Acad Sci U S A. 2016 Jun 14. pii: 201522469.
    PubMed     Text format     Abstract available


  33. SANTOS JM, Duarte N, Kehrer J, Ramesar J, et al
    Maternally supplied S-acyl-transferase is required for crystalloid organelle formation and transmission of the malaria parasite.
    Proc Natl Acad Sci U S A. 2016 Jun 14. pii: 201522381.
    PubMed     Text format     Abstract available


    May 2016
  34. GUNALAN K, Lo E, Hostetler JB, Yewhalaw D, et al
    Role of Plasmodium vivax Duffy-binding protein 1 in invasion of Duffy-null Africans.
    Proc Natl Acad Sci U S A. 2016;113:6271-6.
    PubMed     Text format     Abstract available


  35. CHEN E, Salinas ND, Huang Y, Ntumngia F, et al
    Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein.
    Proc Natl Acad Sci U S A. 2016 May 18. pii: 201600488.
    PubMed     Text format     Abstract available


  36. BERNABEU M, Danziger SA, Avril M, Vaz M, et al
    Severe adult malaria is associated with specific PfEMP1 adhesion types and high parasite biomass.
    Proc Natl Acad Sci U S A. 2016 May 16. pii: 201524294.
    PubMed     Text format     Abstract available


  37. BOONHOK R, Rachaphaew N, Duangmanee A, Chobson P, et al
    LAP-like process as an immune mechanism downstream of IFN-gamma in control of the human malaria Plasmodium vivax liver stage.
    Proc Natl Acad Sci U S A. 2016 May 16. pii: 201525606.
    PubMed     Text format     Abstract available


  38. MOLINA-CRUZ A, Barillas-Mury C
    Mosquito vectors of ape malarias: Another piece of the puzzle.
    Proc Natl Acad Sci U S A. 2016;113:5153-4.
    PubMed     Text format    


    April 2016
  39. MAKANGA B, Yangari P, Rahola N, Rougeron V, et al
    Ape malaria transmission and potential for ape-to-human transfers in Africa.
    Proc Natl Acad Sci U S A. 2016 Apr 11. pii: 201603008.
    PubMed     Text format     Abstract available


  40. BOUR T, Mahmoudi N, Kapps D, Thiberge S, et al
    Apicomplexa-specific tRip facilitates import of exogenous tRNAs into malaria parasites.
    Proc Natl Acad Sci U S A. 2016 Apr 11. pii: 201600476.
    PubMed     Text format     Abstract available


  41. DEARNLEY M, Chu T, Zhang Y, Looker O, et al
    Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages.
    Proc Natl Acad Sci U S A. 2016 Apr 11. pii: 201520194.
    PubMed     Text format     Abstract available


    March 2016
  42. HALL AB, Papathanos PA, Sharma A, Cheng C, et al
    Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes.
    Proc Natl Acad Sci U S A. 2016 Mar 29. pii: 201525164.
    PubMed     Text format     Abstract available


    February 2016
  43. VILLARINO NF, LeCleir GR, Denny JE, Dearth SP, et al
    Composition of the gut microbiota modulates the severity of malaria.
    Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201504887.
    PubMed     Text format     Abstract available


  44. ISMAIL HM, Barton V, Phanchana M, Charoensutthivarakul S, et al
    Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7.
    Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201600459.
    PubMed     Text format     Abstract available


    November 2015
  45. CASANOVA JL
    Human genetic basis of interindividual variability in the course of infection.
    Proc Natl Acad Sci U S A. 2015 Nov 30. pii: 201521644.
    PubMed     Text format     Abstract available


  46. GANTZ VM, Jasinskiene N, Tatarenkova O, Fazekas A, et al
    Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi.
    Proc Natl Acad Sci U S A. 2015 Nov 23. pii: 201521077.
    PubMed     Text format     Abstract available


  47. MOLINA-CRUZ A, Canepa GE, Kamath N, Pavlovic NV, et al
    Plasmodium evasion of mosquito immunity and global malaria transmission: The lock-and-key theory.
    Proc Natl Acad Sci U S A. 2015 Nov 23. pii: 201520426.
    PubMed     Text format     Abstract available


    October 2015
  48. YUDA M, Iwanaga S, Kaneko I, Kato T, et al
    Global transcriptional repression: An initial and essential step for Plasmodium sexual development.
    Proc Natl Acad Sci U S A. 2015;112:12824-9.
    PubMed     Text format     Abstract available


  49. ASSEFA S, Lim C, Preston MD, Duffy CW, et al
    Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi.
    Proc Natl Acad Sci U S A. 2015 Oct 5. pii: 201509534.
    PubMed     Text format     Abstract available


  50. GORDON EB, Hart GT, Tran TM, Waisberg M, et al
    Targeting glutamine metabolism rescues mice from late-stage cerebral malaria.
    Proc Natl Acad Sci U S A. 2015 Oct 5. pii: 201516544.
    PubMed     Text format     Abstract available



  51. Correction for Jimenez-Diaz et al., (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.
    Proc Natl Acad Sci U S A. 2015 Oct 1. pii: 201518632.
    PubMed     Text format    


    September 2015
  52. ANDRIESSEN R, Snetselaar J, Suer RA, Osinga AJ, et al
    Electrostatic coating enhances bioavailability of insecticides and breaks pyrethroid resistance in mosquitoes.
    Proc Natl Acad Sci U S A. 2015;112:12081-6.
    PubMed     Text format     Abstract available


    August 2015
  53. PELLEAU S, Moss EL, Dhingra SK, Volney B, et al
    Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt.
    Proc Natl Acad Sci U S A. 2015 Aug 10. pii: 201507142.
    PubMed     Text format     Abstract available


    July 2015
  54. HELB DA, Tetteh KK, Felgner PL, Skinner J, et al
    Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities.
    Proc Natl Acad Sci U S A. 2015 Jul 27. pii: 201501705.
    PubMed     Text format     Abstract available


    June 2015
  55. LANERI K, Paul RE, Tall A, Faye J, et al
    Dynamical malaria models reveal how immunity buffers effect of climate variability.
    Proc Natl Acad Sci U S A. 2015 Jun 29. pii: 201419047.
    PubMed     Text format     Abstract available


  56. BAUCH SC, Birkenbach AM, Pattanayak SK, Sills EO, et al
    Public health impacts of ecosystem change in the Brazilian Amazon.
    Proc Natl Acad Sci U S A. 2015;112:7414-9.
    PubMed     Text format     Abstract available


    May 2015
  57. GREENHOUSE B, Smith DL
    Malaria genotyping for epidemiologic surveillance.
    Proc Natl Acad Sci U S A. 2015 May 27. pii: 201507727.
    PubMed     Text format    


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