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  Malignant Melanoma

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 32 articles:
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    February 2019
  1. LITSCHKO C, Bruhmann S, Csiszar A, Stephan T, et al
    Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins.
    Proc Natl Acad Sci U S A. 2019;116:3594-3603.
    PubMed     Text format     Abstract available


  2. LI C, Nguyen V, Clark KN, Zahed T, et al
    Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling.
    Proc Natl Acad Sci U S A. 2019 Feb 21. pii: 1813802116.
    PubMed     Text format     Abstract available


  3. GUPTA R, Bugide S, Wang B, Green MR, et al
    Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway.
    Proc Natl Acad Sci U S A. 2019 Feb 19. pii: 1821889116.
    PubMed     Text format     Abstract available


  4. CHEUNG LS, Fu J, Kumar P, Kumar A, et al
    Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma.
    Proc Natl Acad Sci U S A. 2019 Feb 4. pii: 1815087116.
    PubMed     Text format     Abstract available


    January 2019
  5. MIROSHNICHENKO SK, Patutina OA, Burakova EA, Chelobanov BP, et al
    Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.
    Proc Natl Acad Sci U S A. 2019;116:1229-1234.
    PubMed     Text format     Abstract available


  6. BLANDO J, Sharma A, Higa MG, Zhao H, et al
    Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2019 Jan 11. pii: 1811067116.
    PubMed     Text format     Abstract available


  7. SANTANA CARRERO RM, Beceren-Braun F, Rivas SC, Hegde SM, et al
    IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses.
    Proc Natl Acad Sci U S A. 2019;116:599-608.
    PubMed     Text format     Abstract available


    December 2018
  8. DU X, de Almeida P, Manieri N, de Almeida Nagata D, et al
    CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1.
    Proc Natl Acad Sci U S A. 2018;115:E11731-E11740.
    PubMed     Text format     Abstract available


  9. SANG B, Zhang YY, Guo ST, Kong LF, et al
    Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
    Proc Natl Acad Sci U S A. 2018;115:E11661-E11670.
    PubMed     Text format     Abstract available


    September 2018
  10. NGEOW KC, Friedrichsen HJ, Li L, Zeng Z, et al
    BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.
    Proc Natl Acad Sci U S A. 2018;115:E8668-E8677.
    PubMed     Text format     Abstract available


    August 2018
  11. WANG Y, Su L, Morin MD, Jones BT, et al
    Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice.
    Proc Natl Acad Sci U S A. 2018 Aug 27. pii: 1809232115.
    PubMed     Text format     Abstract available


  12. YANG Y, Jang GB, Yang X, Wang Q, et al
    Central role of autophagic UVRAG in melanogenesis and the suntan response.
    Proc Natl Acad Sci U S A. 2018;115:E7728-E7737.
    PubMed     Text format     Abstract available


  13. DATTA S, Misra SK, Saha ML, Lahiri N, et al
    Orthogonal self-assembly of an organoplatinum(II) metallacycle and cucurbit[8]uril that delivers curcumin to cancer cells.
    Proc Natl Acad Sci U S A. 2018;115:8087-8092.
    PubMed     Text format     Abstract available


    June 2018
  14. DE SEMIR D, Bezrookove V, Nosrati M, Dar AA, et al
    PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
    Proc Natl Acad Sci U S A. 2018 Jun 4. pii: 1804779115.
    PubMed     Text format     Abstract available


    April 2018
  15. ZHAO L, Huang S, Mei S, Yang Z, et al
    Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.
    Proc Natl Acad Sci U S A. 2018;115:E3673-E3681.
    PubMed     Text format     Abstract available


    March 2018
  16. LI J, Wu C, Wang W, He Y, et al
    Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference.
    Proc Natl Acad Sci U S A. 2018;115:E2696-E2705.
    PubMed     Text format     Abstract available


    February 2018
  17. YATES K, Bi K, Haining WN, Cantor H, et al
    Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells.
    Proc Natl Acad Sci U S A. 2018;115:2162-2167.
    PubMed     Text format     Abstract available


  18. HONG X, Sullivan RJ, Kalinich M, Kwan TT, et al
    Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.
    Proc Natl Acad Sci U S A. 2018 Feb 16. pii: 1719264115.
    PubMed     Text format     Abstract available


    January 2018
  19. TAGGART D, Andreou T, Scott KJ, Williams J, et al
    Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8(+) T cell trafficking.
    Proc Natl Acad Sci U S A. 2018 Jan 31. pii: 1714089115.
    PubMed     Text format     Abstract available


    December 2017
  20. SU Y, Wei W, Robert L, Xue M, et al
    Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
    Proc Natl Acad Sci U S A. 2017 Dec 11. pii: 1712064115.
    PubMed     Text format     Abstract available


    October 2017
  21. MGRDITCHIAN T, Arakelian T, Paggetti J, Noman MZ, et al
    Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.
    Proc Natl Acad Sci U S A. 2017;114:E9271-E9279.
    PubMed     Text format     Abstract available


    September 2017
  22. INGRAM JR, Blomberg OS, Sockolosky JT, Ali L, et al
    Localized CD47 blockade enhances immunotherapy for murine melanoma.
    Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201710776.
    PubMed     Text format     Abstract available


    August 2017
  23. DUGGAN MC, Stiff AR, Bainazar M, Regan K, et al
    Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.
    Proc Natl Acad Sci U S A. 2017 Aug 21. pii: 201704371.
    PubMed     Text format     Abstract available


    July 2017
  24. DU W, Seah I, Bougazzoul O, Choi G, et al
    Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas.
    Proc Natl Acad Sci U S A. 2017 Jul 14. pii: 201700363.
    PubMed     Text format     Abstract available


  25. LUNAVAT TR, Cheng L, Einarsdottir BO, Olofsson Bagge R, et al
    BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.
    Proc Natl Acad Sci U S A. 2017 Jul 6. pii: 201705206.
    PubMed     Text format     Abstract available


    June 2017
  26. TURRIANI E, Lazaro DF, Ryazanov S, Leonov A, et al
    Treatment with diphenyl-pyrazole compound anle138b/c reveals that alpha-synuclein protects melanoma cells from autophagic cell death.
    Proc Natl Acad Sci U S A. 2017 Jun 5. pii: 201700200.
    PubMed     Text format     Abstract available


    December 2016
  27. KEGELMAN TP, Wu B, Das SK, Talukdar S, et al
    Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.
    Proc Natl Acad Sci U S A. 2016 Dec 23. pii: 201616100.
    PubMed     Text format     Abstract available


    November 2016
  28. LI Y, Cheng HS, Chng WJ, Tergaonkar V, et al
    Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.
    Proc Natl Acad Sci U S A. 2016 Nov 23. pii: 201611106.
    PubMed     Text format     Abstract available


  29. DANILOVA L, Wang H, Sunshine J, Kaunitz GJ, et al
    Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors.
    Proc Natl Acad Sci U S A. 2016 Nov 11. pii: 201607836.
    PubMed     Text format     Abstract available


  30. SPRANGER S, Luke JJ, Bao R, Zha Y, et al
    Density of immunogenic antigens does not explain the presence or absence of the T-cell-inflamed tumor microenvironment in melanoma.
    Proc Natl Acad Sci U S A. 2016 Nov 11. pii: 201609376.
    PubMed     Text format     Abstract available


    May 2016
  31. NAKAGAWA H, Sido JM, Reyes EE, Kiers V, et al
    Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity.
    Proc Natl Acad Sci U S A. 2016;113:6248-53.
    PubMed     Text format     Abstract available


    April 2016
  32. ADAR S, Hu J, Lieb JD, Sancar A, et al
    Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis.
    Proc Natl Acad Sci U S A. 2016;113:E2124-33.
    PubMed     Text format     Abstract available


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