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Multiple Sclerosis

Free Subscription Articles published in J Clin Invest Retrieve available abstracts of 20 articles: HTML format

Single Articles

October 2025
1. WU C, Jiang M, Yang X, Liu Y, et al
   ANKRD55 is a key regulator of T cell inflammation in multiple sclerosis.
   J Clin Invest. 2025;135:e195214.
   PubMed     Abstract available
   
   
   July 2025
2. HUGHES EP, Syage AR, Mirzaei Mehrabad E, Lane TE, et al
   OCA-B promotes pathogenic maturation of stem-like CD4+ T cells and autoimmune demyelination.
   J Clin Invest. 2025;135:e187862.
   PubMed     Abstract available
   
   
   June 2025
3. POLONIO CM, Quintana FJ
   Therapeutic B cell depletion identifies immunoregulatory networks.
   J Clin Invest. 2025;135:e189442.
   PubMed     Abstract available
   
   
   May 2025
4. KOCOT J, Kosa P, Ashida S, Pirjanian NA, et al
   Clemastine fumarate accelerates accumulation of disability in progressive multiple sclerosis by enhancing pyroptosis.
   J Clin Invest. 2025;135:e183941.
   PubMed     Abstract available
   
   
   March 2025
5. WEI J, Moon J, Yasumizu Y, Zhang L, et al
   Transcriptomic profiling after B-cell depletion reveals central and peripheral immune cell changes in multiple sclerosis.
   J Clin Invest. 2025 Mar 11:e182790. doi: 10.1172/JCI182790.
   PubMed     Abstract available
   
   
   
6. DICILLO EB, Kountikov E, Zhu M, Lanker S, et al
   Patterns of autoantibody expression in multiple sclerosis identified through development of an autoantigen discovery technology.
   J Clin Invest. 2025;135:e171948.
   PubMed     Abstract available
   
   
   January 2025
7. CANTONI C, Smirnov RA, Firulyova M, Andhey PS, et al
   A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations.
   J Clin Invest. 2025;135:e177793.
   PubMed     Abstract available
   
   
   December 2024
8. VERMA SC, Enee E, Manasse K, Rebhi F, et al
   Cathelicidin antimicrobial peptide expression in neutrophils and neurons antagonistically modulates neuroinflammation.
   J Clin Invest. 2024;135:e184502.
   PubMed     Abstract available
   
   
   November 2024
9. VIETZEN H, Kuhner LM, Berger SM, Furlano PL, et al
   Accumulation of Epstein-Barr virus-induced cross-reactive immune responses is associated with multiple sclerosis.
   J Clin Invest. 2024;134:e184481.
   PubMed    
   
   
   September 2024
10. FONDELLI F, Willemyns J, Domenech-Garcia R, Mansilla MJ, et al
    Targeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis.
    J Clin Invest. 2024 Sep 17:e178949. doi: 10.1172/JCI178949.
    PubMed     Abstract available
    
    
    June 2024
11. WOO MS, Bal LC, Winschel I, Manca E, et al
    The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis.
    J Clin Invest. 2024;134:e177692.
    PubMed     Abstract available
    
    
    May 2024
12. GHORBANI S, Li C, Lozinski BM, Moezzi D, et al
    Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis.
    J Clin Invest. 2024 May 14:e176910. doi: 10.1172/JCI176910.
    PubMed     Abstract available
    
    
    December 2023
13. JOHANN L, Soldati S, Muller K, Lampe J, et al
    A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS.
    J Clin Invest. 2023;133:e168314.
    PubMed     Abstract available
    
    
    September 2023
14. CLARKSON BD, Grund EM, Standiford MM, Mirchia K, et al
    CD8+ T cells recognizing a neuron-restricted antigen injure axons in a model of multiple sclerosis.
    J Clin Invest. 2023 Sep 7:e162788. doi: 10.1172/JCI162788.
    PubMed     Abstract available
    
    
    August 2023
15. OWENS GP, Fellin TJ, Matschulat A, Salas V, et al
    Pathogenic myelin specific antibodies in multiple sclerosis target conformational proteolipid protein 1 anchored membrane domains.
    J Clin Invest. 2023 Aug 10:e162731. doi: 10.1172/JCI162731.
    PubMed     Abstract available
    
    
    May 2023
16. KERKERING J, Muinjonov B, Rosiewicz KS, Diecke S, et al
    iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
    J Clin Invest. 2023 May 23:e164637. doi: 10.1172/JCI164637.
    PubMed     Abstract available
    
    
    
17. REDER AT
    Clostridium epsilon toxin is excessive in multiple sclerosis and provokes multifocal lesions in mouse models.
    J Clin Invest. 2023;133:e169643.
    PubMed     Abstract available
    
    
    
18. MA Y, Sannino D, Linden JR, Haigh S, et al
    Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege.
    J Clin Invest. 2023;133:e163239.
    PubMed     Abstract available
    
    
    April 2023
19. ANTEL JP, Kennedy TE, Kuhlmann T
    Seeking neuroprotection in multiple sclerosis: an ongoing challenge.
    J Clin Invest. 2023;133:e168595.
    PubMed     Abstract available
    
    
    
20. KAPELL H, Fazio L, Dyckow J, Schwarz S, et al
    Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
    J Clin Invest. 2023;133:e164223.
    PubMed     Abstract available
    
    

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