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COVID-19: Daily Top 10 Papers


  Obstructive Lung Diseases

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Articles published in Am J Respir Crit Care Med

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    December 2021
  1. BRADDING P
    Mechanisms of Mast Cell Activation in Severe Asthma - Beyond IgE.
    Am J Respir Crit Care Med. 2021 Dec 2. doi: 10.1164/rccm.202110-2322.
    PubMed    


    November 2021
  2. CARR TF, Kraft M
    Gaining Insights into Asthma-related COVID-19 Risk.
    Am J Respir Crit Care Med. 2021 Nov 23. doi: 10.1164/rccm.202111-2473.
    PubMed    


  3. TIOTIU A, Badi Y, Kermani NZ, Sanak M, et al
    Association of Differential Mast Cell Activation to Granulocytic Inflammation in Severe Asthma.
    Am J Respir Crit Care Med. 2021 Nov 23. doi: 10.1164/rccm.202102-0355.
    PubMed     Abstract available


  4. VAN DEN BERGE M, Faiz A
    Transcriptome Based Signatures: The Future Biomarkers in Obstructive Pulmonary Diseases Such as Asthma and COPD?
    Am J Respir Crit Care Med. 2021 Nov 18. doi: 10.1164/rccm.202110-2353.
    PubMed    


  5. KHATRI SB, Iaccarino JM, Barochia A, Soghier I, et al
    Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline.
    Am J Respir Crit Care Med. 2021;204:e97-e109.
    PubMed     Abstract available


  6. KELLY RS, Mendez KM, Huang M, Hobbs BD, et al
    Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in two TOPMed Cohorts.
    Am J Respir Crit Care Med. 2021 Nov 12. doi: 10.1164/rccm.202105-1268.
    PubMed     Abstract available


  7. NICI L
    Pulmonary Rehabilitation after a Chronic Obstructive Pulmonary Disease Exacerbation: Impact on Readmission Risk in a Real-World Setting.
    Am J Respir Crit Care Med. 2021;204:1005-1006.
    PubMed    


  8. KAMAL F, Kumar S, Edwards MR, Veselkov K, et al
    Virus-induced Volatile Organic Compounds Are Detectable in Exhaled Breath during Pulmonary Infection.
    Am J Respir Crit Care Med. 2021;204:1075-1085.
    PubMed     Abstract available


  9. STEFAN MS, Pekow PS, Priya A, ZuWallack R, et al
    Association between Initiation of Pulmonary Rehabilitation and Rehospitalizations in Patients Hospitalized with Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;204:1015-1023.
    PubMed     Abstract available


    October 2021
  10. BLOOM CI, Cullinan P, Wedzicha JA
    Asthma Phenotypes and COVID-19 Risk: A Population-based Observational Study.
    Am J Respir Crit Care Med. 2021 Oct 20. doi: 10.1164/rccm.202107-1704.
    PubMed     Abstract available


  11. REDDEL HK, Bacharier LB, Bateman ED, Brightling CE, et al
    Global Initiative for Asthma (GINA) Strategy 2021 - Executive Summary and Rationale for Key Changes.
    Am J Respir Crit Care Med. 2021 Oct 18. doi: 10.1164/rccm.202109-2205.
    PubMed     Abstract available


  12. ROZENBERG D, McInnis M, Chow CW
    Using Automated Radiographic Signatures to Prognosticate Chronic Lung Allograft Dysfunction: What Does the Future Hold?
    Am J Respir Crit Care Med. 2021;204:883-885.
    PubMed    


  13. VAMEGHESTAHBANATI M, Kirby M, Maltais F, Jensen D, et al
    Dysanapsis and the Spirometric Response to Inhaled Bronchodilators.
    Am J Respir Crit Care Med. 2021;204:997-1001.
    PubMed    


  14. NARAOKA T, Sumi T, Keira Y, Nakata H, et al
    Epirubicin and Cyclophosphamide-induced Acute Fibrinous and Organizing Pneumonia.
    Am J Respir Crit Care Med. 2021;204:e92-e93.
    PubMed    


  15. VANSTAPEL A, Weynand B, Kaes J, Neyrinck AP, et al
    Interalveolar Pores Increase in Aging and Severe Airway Obstruction.
    Am J Respir Crit Care Med. 2021;204:862-865.
    PubMed    


  16. VAN DER MOLEN MC, Hartman JE, Vermeulen CJ, van den Berge M, et al
    Determinants of Lung Fissure Completeness.
    Am J Respir Crit Care Med. 2021;204:807-816.
    PubMed     Abstract available


    September 2021
  17. HERSHENSON MB
    ILC2s in Viral-Induced Asthma Exacerbations: A Starring or Supportive Role?
    Am J Respir Crit Care Med. 2021 Sep 28. doi: 10.1164/rccm.202108-2001.
    PubMed    


  18. RACANELLI AC, Choi AMK
    The Saga of Necroptosis in Chronic Obstructive Pulmonary Disease Continues.
    Am J Respir Crit Care Med. 2021;204:622-624.
    PubMed    


  19. KUNOE A, Sevelsted A, Chawes BL, Stokholm J, et al
    Associations between Inhaled Corticosteroid Use in the First 6 Years of Life and Obesity-related Traits.
    Am J Respir Crit Care Med. 2021;204:642-650.
    PubMed     Abstract available


  20. DHARIWAL J, Cameron A, Wong E, Paulsen M, et al
    Pulmonary Innate Lymphoid Cell Responses during Rhinovirus-induced Asthma Exacerbations In Vivo: A Clinical Trial.
    Am J Respir Crit Care Med. 2021 Sep 1. doi: 10.1164/rccm.202010-3754.
    PubMed     Abstract available


  21. BALMES JR
    Place Matters: Residential Racial Segregation and Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;204:496-498.
    PubMed    


  22. VOLERMAN A, Lowe AA, Pappalardo AA, Anderson CMC, et al
    Ensuring Access to Albuterol in Schools: From Policy to Implementation. An Official ATS/AANMA/ALA/NASN Policy Statement.
    Am J Respir Crit Care Med. 2021;204:508-522.
    PubMed     Abstract available


  23. WOO H, Brigham EP, Allbright K, Ejike C, et al
    Racial Segregation and Respiratory Outcomes among Urban Black Residents with and at Risk of Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;204:536-545.
    PubMed     Abstract available


  24. ROBINSON PFM, Fontanella S, Ananth S, Martin Alonso A, et al
    Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes.
    Am J Respir Crit Care Med. 2021;204:523-535.
    PubMed     Abstract available


    August 2021
  25. WADE RC, Simmons JP, Boueiz A, Gregory A, et al
    Pulmonary Artery Enlargement Is Associated with Exacerbations and Mortality in Ever-Smokers with Preserved Ratio Impaired Spirometry.
    Am J Respir Crit Care Med. 2021;204:481-485.
    PubMed    


  26. HOLT P, Strickland D
    Innate Immune Training for Prevention of Recurrent Wheeze in Early Childhood.
    Am J Respir Crit Care Med. 2021;204:392-394.
    PubMed    


  27. IKARI K, Tezuka J, Matsumoto T, Tsuji M, et al
    Charcot-Leyden Crystals in Rapidly Progressing Plastic Bronchitis.
    Am J Respir Crit Care Med. 2021;204:e54-e55.
    PubMed    


  28. METERSKY ML
    Fewer Bronchiectasis Exacerbations During the "Lockdown" for COVID-19: Can We Convert Knowledge into Action?
    Am J Respir Crit Care Med. 2021 Aug 12. doi: 10.1164/rccm.202107-1731.
    PubMed    


  29. BEAMER PI, Lothrop N
    Before the First Breath: Prenatal Ultrafine Particulate Exposure and Incident Asthma.
    Am J Respir Crit Care Med. 2021 Aug 4. doi: 10.1164/rccm.202106-1356.
    PubMed    


  30. FORNO E, Abman SH, Singh J, Robbins ME, et al
    Update in Pediatrics 2020.
    Am J Respir Crit Care Med. 2021;204:274-284.
    PubMed    


  31. MACINTYRE CR, Nguyen PY, Trent M, Seale H, et al
    Adverse Health Effects in People with and without Preexisting Respiratory Conditions during Bushfire Smoke Exposure in the 2019/2020 Australian Summer.
    Am J Respir Crit Care Med. 2021;204:368-371.
    PubMed    


  32. ALOTAIBI NM, Filho FSL, Mattman A, Hollander Z, et al
    IgG Levels and Mortality in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;204:362-365.
    PubMed    


    July 2021
  33. CRICHTON ML, Shoemark A, Chalmers JD
    The Impact of the COVID-19 Pandemic on Exacerbations and Symptoms in Bronchiectasis: A Prospective Study.
    Am J Respir Crit Care Med. 2021 Jul 15. doi: 10.1164/rccm.202105-1137.
    PubMed    


  34. POPE III CA
    Are Adults with Chronic Obstructive Pulmonary Disease Vulnerable to Air Pollution and Cardiovascular Risk?
    Am J Respir Crit Care Med. 2021;204:116-118.
    PubMed    


  35. ALEXEEFF SE, Deosaransingh K, Liao NS, Van Den Eeden SK, et al
    Particulate Matter and Cardiovascular Risk in Adults with Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;204:159-167.
    PubMed     Abstract available


  36. NEDER JA, de-Torres JP, O'Donnell DE
    Exposing Pre-Chronic Obstructive Pulmonary Disease: When Physiology Matters!
    Am J Respir Crit Care Med. 2021;204:110-111.
    PubMed    


  37. WOUTERS EFM
    Pre-Chronic Obstructive Pulmonary Disease: Toward the Limits of the Spirometric Funnel.
    Am J Respir Crit Care Med. 2021;204:112.
    PubMed    


  38. RITCHIE AI, Baker JR, Parekh TM, Allinson JP, et al
    Update in Chronic Obstructive Pulmonary Disease 2020.
    Am J Respir Crit Care Med. 2021;204:14-22.
    PubMed    


    June 2021
  39. PETRACHE I, Serban KA
    Can Metformin Downshift the Gears of Aging to Slow Emphysema Progression?
    Am J Respir Crit Care Med. 2021 Jun 30. doi: 10.1164/rccm.202105-1273.
    PubMed    


  40. POLVERINO F, Soriano JB
    Asthma and COPD: Just Old Friends or Relatives?
    Am J Respir Crit Care Med. 2021 Jun 30. doi: 10.1164/rccm.202106-1358.
    PubMed    


  41. HALAYKO AJ, Pascoe CD, Gereige JD, Peters MC, et al
    Update in Adult Asthma 2020.
    Am J Respir Crit Care Med. 2021 Jun 28. doi: 10.1164/rccm.202103-0552.
    PubMed    


  42. LU Z, Van Eeckhoutte HP, Liu G, Nair PM, et al
    Necroptosis Signalling Promotes Inflammation, Airway Remodelling and Emphysema in COPD.
    Am J Respir Crit Care Med. 2021 Jun 16. doi: 10.1164/rccm.202009-3442.
    PubMed     Abstract available


  43. COUILLARD S, Shrimanker R, Chaudhuri R, Mansur AH, et al
    FeNO Non-Suppression Identifies Corticosteroid-Resistant Type-2 Signaling in Severe Asthma.
    Am J Respir Crit Care Med. 2021 Jun 15. doi: 10.1164/rccm.202104-1040.
    PubMed    


  44. SEGAL LN, Huang YJ
    Crossing Kingdoms: Host-Microbial Endotyping and the Quest to Understand Treatable Traits in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:1447-1448.
    PubMed    


  45. CRIM C, Frith LJ, Midwinter D, Donohue JF, et al
    FEV1 Minimum Important Difference versus Minimal Detectable Difference? In Search of the Unicorn.
    Am J Respir Crit Care Med. 2021;203:1573-1576.
    PubMed    


  46. GARNER JL, Biddiscombe MF, Meah S, Lewis A, et al
    Endobronchial Valve Lung Volume Reduction and Small Airway Function.
    Am J Respir Crit Care Med. 2021;203:1576-1579.
    PubMed    


  47. WANG Z, Locantore N, Haldar K, Ramsheh MY, et al
    Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis.
    Am J Respir Crit Care Med. 2021;203:1488-1502.
    PubMed     Abstract available


  48. CHAPMAN KR
    Chronic Obstructive Pulmonary Disease: Is Social Injustice the Elephant in the Room?
    Am J Respir Crit Care Med. 2021;203:1331-1332.
    PubMed    


    May 2021
  49. POLVERINO F, Wu TD, Rojas-Quintero J, Wang X, et al
    Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.
    Am J Respir Crit Care Med. 2021 May 25. doi: 10.1164/rccm.202012-4510.
    PubMed     Abstract available


  50. IZADI N, Baraghoshi D, Curran-Everett D, Zeiger RS, et al
    Factors Associated with Persistence of Severe Asthma from Late Adolescence to Early Adulthood.
    Am J Respir Crit Care Med. 2021 May 24. doi: 10.1164/rccm.202010-3763.
    PubMed     Abstract available


  51. WRIGHT RJ, Hsu HL, Chiu YM, Coull BA, et al
    Prenatal Ambient Ultrafine Particle Exposure and Childhood Asthma in the Northeastern United States.
    Am J Respir Crit Care Med. 2021 May 21. doi: 10.1164/rccm.202010-3743.
    PubMed     Abstract available


  52. SCHIPKE J, Kuhlmann S, Hegermann J, Fassbender S, et al
    Lipofibroblasts in Structurally Normal, Fibrotic and Emphysematous Human Lungs.
    Am J Respir Crit Care Med. 2021 May 20. doi: 10.1164/rccm.202101-0043.
    PubMed    


  53. SEVILLA-MONTERO J, Labrousse-Arias D, Fernandez-Perez C, Fernandez-Blanco L, et al
    Cigarette Smoke Directly Promotes Pulmonary Arterial Remodeling and Kv7.4 Channel Dysfunction.
    Am J Respir Crit Care Med. 2021;203:1290-1305.
    PubMed     Abstract available


  54. RITCHIE AI, Martinez FJ
    The Challenges of Defining Early Chronic Obstructive Pulmonary Disease in the General Population.
    Am J Respir Crit Care Med. 2021;203:1209-1210.
    PubMed    


  55. COLAK Y, Afzal S, Nordestgaard BG, Lange P, et al
    Importance of Early COPD in Young Adults for Development of Clinical COPD: Findings from the Copenhagen General Population Study.
    Am J Respir Crit Care Med. 2021;203:1245-1256.
    PubMed     Abstract available


  56. TAKUMA S, Kusagaya H, Nakuamura S, Mori R, et al
    Systemic Air Embolism and Mediastinal Emphysema After Pneumonia.
    Am J Respir Crit Care Med. 2021 May 10. doi: 10.1164/rccm.202002-0266.
    PubMed    


  57. CUSACK RP, Nagashima A, Sehmi R
    Airway Androgen Receptor Expression - Regulators of Sex Differences in Asthma?
    Am J Respir Crit Care Med. 2021 May 5. doi: 10.1164/rccm.202104-0869.
    PubMed    


  58. GERSHON AS, McGihon RE, Luo J, Blazer AJ, et al
    Trends in Chronic Obstructive Pulmonary Disease Prevalence, Incidence, and Health Services Use in Younger Adults in Ontario, Canada, 2006-2016.
    Am J Respir Crit Care Med. 2021;203:1196-1199.
    PubMed    


  59. GARCIA E, Rice MB
    It's Not Just a Smoking-related Disease: Outdoor Pollution May Increase Risk of Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:1057-1058.
    PubMed    


    April 2021
  60. CHASSAGNON G, Burgel PR
    Mucus Plugs in Medium-sized Airways: A Novel Imaging Biomarker for Phenotyping Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:932-934.
    PubMed    


  61. BHATTA L, Leivseth L, Mai XM, Henriksen AH, et al
    Spirometric Classifications of Chronic Obstructive Pulmonary Disease Severity as Predictive Markers for Clinical Outcomes: The HUNT Study.
    Am J Respir Crit Care Med. 2021;203:1033-1037.
    PubMed    


  62. EJIKE CO, Woo H, Galiatsatos P, Paulin LM, et al
    Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes.
    Am J Respir Crit Care Med. 2021;203:987-997.
    PubMed     Abstract available


  63. THOMSON NC
    Asthma with a Smoking History and Pre-COPD.
    Am J Respir Crit Care Med. 2021 Apr 8. doi: 10.1164/rccm.202102-0440.
    PubMed    


  64. LIPSON DA, Han MK, Wise R, Martinez FJ, et al
    Reply to Lopez-Campos et al.: Triple-Therapy Trials for Chronic Obstructive Pulmonary Disease: Methodological Considerations in the Mortality Effect.
    Am J Respir Crit Care Med. 2021;203:928-929.
    PubMed    


  65. ROGLIANI P, Calzetta L
    Mortality in ETHOS: A Question of "Power".
    Am J Respir Crit Care Med. 2021;203:926-927.
    PubMed    


  66. MARTINEZ FJ, Darken P, Dorinsky P
    Reply to Lopez-Campos et al. and to Rogliani and Calzetta.
    Am J Respir Crit Care Med. 2021;203:927-928.
    PubMed    


  67. HALLMARK B, Wegienka G, Havstad S, Billheimer D, et al
    Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood.
    Am J Respir Crit Care Med. 2021;203:864-870.
    PubMed     Abstract available


  68. LOPEZ-CAMPOS JL, Fernandez-Villar A, Ruano-Ravina A
    Triple-Therapy Trials for Chronic Obstructive Pulmonary Disease: Methodological Considerations in the Mortality Effect.
    Am J Respir Crit Care Med. 2021;203:925-926.
    PubMed    


  69. CHOI T, Devries M, Bacharier LB, Busse W, et al
    Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection.
    Am J Respir Crit Care Med. 2021;203:822-830.
    PubMed     Abstract available


    March 2021
  70. BEASLEY R, Bruce P, Hatter L, Braithwaite I, et al
    A Proposed Revision of the Stepwise Treatment Algorithm in Asthma.
    Am J Respir Crit Care Med. 2021 Mar 31. doi: 10.1164/rccm.202101-0224.
    PubMed    


  71. ZEIN JG, McManus JM, Sharifi N, Erzurum SC, et al
    Benefits of Airway Androgen Receptor Expression in Human Asthma.
    Am J Respir Crit Care Med. 2021 Mar 29. doi: 10.1164/rccm.202009-3720.
    PubMed     Abstract available


  72. YILMAZ I, Cetin GP
    The Visible and Invisible Faces of the Iceberg of Type 2 Asthma.
    Am J Respir Crit Care Med. 2021 Mar 17. doi: 10.1164/rccm.202102-0291.
    PubMed    


  73. WENZEL SE
    Reply to: The Visible and Invisible Faces of the Iceberg of Type 2 Asthma.
    Am J Respir Crit Care Med. 2021 Mar 17. doi: 10.1164/rccm.202102-0398.
    PubMed    


  74. THORSEN J, Stokholm J, Rasmussen MA, Mortensen MS, et al
    The Airway Microbiota Modulates Effect of Azithromycin Treatment for Episodes of Recurrent Asthma-like Symptoms in Preschool Children: A Randomized Clinical Trial.
    Am J Respir Crit Care Med. 2021 Mar 17. doi: 10.1164/rccm.202008-3226.
    PubMed     Abstract available


  75. PAPI A, Beghe B, Fabbri LM
    Rate of Decline of FEV1 as a Biomarker of Survival?
    Am J Respir Crit Care Med. 2021;203:663-665.
    PubMed    


  76. CELLI BR, Anderson JA, Cowans NJ, Crim C, et al
    Pharmacotherapy and Lung Function Decline in Patients with Chronic Obstructive Pulmonary Disease. A Systematic Review.
    Am J Respir Crit Care Med. 2021;203:689-698.
    PubMed     Abstract available


  77. CALVERLEY P
    Reigniting the TORCH: Chronic Obstructive Pulmonary Disease Mortality and Inhaled Corticosteroids Revisited.
    Am J Respir Crit Care Med. 2021;203:531-532.
    PubMed    


  78. MARTINEZ-GARCIA MA, Agusti A
    Lack of Bacterial Colonization Measure in Randomized Controlled Trial on Inhaled Corticosteroids Effect in Patients with Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:651.
    PubMed    


  79. PUEBLA NEIRA DA, Hsu ES, Kuo YF, Ottenbacher KJ, et al
    Reply to Lindenauer et al.: Apparent Increase in Chronic Obstructive Pulmonary Disease Mortality Is Likely an Artifact of Changes in Documentation and Coding.
    Am J Respir Crit Care Med. 2021;203:649-651.
    PubMed    


  80. LINDENAUER PK, Yu H, Grady J, Dorsey K, et al
    Apparent Increase in Chronic Obstructive Pulmonary Disease Mortality Is Likely an Artifact of Changes in Documentation and Coding.
    Am J Respir Crit Care Med. 2021;203:647-649.
    PubMed    


  81. MARTINEZ FJ, Rabe KF, Ferguson GT, Wedzicha JA, et al
    Reduced All-Cause Mortality in the ETHOS Trial of Budesonide/Glycopyrrolate/Formoterol for Chronic Obstructive Pulmonary Disease. A Randomized, Double-Blind, Multicenter, Parallel-Group Study.
    Am J Respir Crit Care Med. 2021;203:553-564.
    PubMed     Abstract available


  82. OULEGO-ERROZ I, Martinez-Saenz de Jubera J, Ocana-Alcober C, Regueras-Santos L, et al
    Pediatric Catastrophic Antiphospholipid Syndrome Successfully Treated with Eculizumab.
    Am J Respir Crit Care Med. 2021;203:640-642.
    PubMed    


    February 2021
  83. KOLMERT J, Dahlen SE, Wheelock CE
    Reply to: Exposure to Active and Passive Tobacco Smoke on Urinary Eicosanoid Metabolites in Type 2 Asthma.
    Am J Respir Crit Care Med. 2021 Feb 23. doi: 10.1164/rccm.202101-0208.
    PubMed    


  84. THOMSON NC
    Exposure to Active and Passive Tobacco Smoke on Urinary Eicosanoid Metabolites in Type 2 Asthma.
    Am J Respir Crit Care Med. 2021 Feb 23. doi: 10.1164/rccm.202101-0011.
    PubMed    


  85. KOPPELMAN GH, Kersten ETG
    Understanding How Asthma Starts: Longitudinal Patterns of Wheeze and the Chromosome 17q Locus.
    Am J Respir Crit Care Med. 2021 Feb 23. doi: 10.1164/rccm.202102-0443.
    PubMed    


  86. ONO JG, Worgall S
    More Evidence for Inborn Dysregulation of Sphingolipid Metabolism in Children with Asthma?
    Am J Respir Crit Care Med. 2021 Feb 22. doi: 10.1164/rccm.202102-0419.
    PubMed    


  87. LOUIS RE, Schleich FN
    Granulocytic Airway Inflammation and Clinical Asthma Outcomes.
    Am J Respir Crit Care Med. 2021 Feb 19. doi: 10.1164/rccm.202102-0356.
    PubMed    


  88. BEASLEY R, Hills T, Kearns N
    Asthma and COVID-19: Preconceptions About Predisposition.
    Am J Respir Crit Care Med. 2021 Feb 18. doi: 10.1164/rccm.202102-0266.
    PubMed    


  89. MARTINEZ FD
    Asthma in the Time of COVID-19.
    Am J Respir Crit Care Med. 2021 Feb 18. doi: 10.1164/rccm.202102-0389.
    PubMed    


  90. LABEDZ SL, Krishnan JA
    Time to Revisit the Hospital Readmissions Reduction Program for Patients Hospitalized for Chronic Obstructive Pulmonary Disease Exacerbations.
    Am J Respir Crit Care Med. 2021;203:403-404.
    PubMed    


  91. HAN MK, Agusti A, Celli BR, Criner GJ, et al
    From GOLD 0 to Pre-COPD.
    Am J Respir Crit Care Med. 2021;203:414-423.
    PubMed    


  92. HUDALI TH, Bodduluri S, Dransfield MT, Bhatt SP, et al
    Association between Inhaled Corticosteroids and Expiratory Central Airway Collapse in Smokers.
    Am J Respir Crit Care Med. 2021;203:518-521.
    PubMed    


  93. PUEBLA NEIRA DA, Hsu ES, Kuo YF, Ottenbacher KJ, et al
    Readmissions Reduction Program: Mortality and Readmissions for Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:437-446.
    PubMed     Abstract available


  94. HASTIE AT, Mauger DT, Denlinger LC, Coverstone A, et al
    Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program.
    Am J Respir Crit Care Med. 2021 Feb 5. doi: 10.1164/rccm.202009-3713.
    PubMed     Abstract available


  95. RAGO D, Pedersen CT, Huang M, Kelly RS, et al
    Characteristics and Mechanisms of a Sphingolipid-associated Childhood Asthma Endotype.
    Am J Respir Crit Care Med. 2021 Feb 3. doi: 10.1164/rccm.202008-3206.
    PubMed     Abstract available


  96. GIOSA L, Busana M, Bonifazi M, Romitti F, et al
    Mobilizing Carbon Dioxide Stores. An Experimental Study.
    Am J Respir Crit Care Med. 2021;203:318-327.
    PubMed     Abstract available


    January 2021
  97. WATCHORN D, O'Shea D, Butler MW
    Asthma Exacerbations in Individuals on Glucagon-Like Peptide-1 Receptor Agonists for Type 2 Diabetes.
    Am J Respir Crit Care Med. 2021 Jan 28. doi: 10.1164/rccm.202011-4162.
    PubMed    


  98. FOER D, Beeler PE, Cui J, Karlson EW, et al
    Reply to: Asthma Exacerbations in Individuals on Glucagon-Like Peptide-1 Receptor Agonists for Type 2 Diabetes.
    Am J Respir Crit Care Med. 2021 Jan 28. doi: 10.1164/rccm.202012-4511.
    PubMed    


  99. LYNCH SV, Vercelli D
    Microbiota, Epigenetics and Trained Immunity: Convergent Drivers and Mediators of the Asthma Trajectory from Pregnancy to Childhood.
    Am J Respir Crit Care Med. 2021 Jan 25. doi: 10.1164/rccm.202010-3779.
    PubMed     Abstract available


  100. TERRY PD, Heidel RE, Dhand R
    Asthma in Adult Patients with COVID-19: Prevalence and Risk of Severe Disease.
    Am J Respir Crit Care Med. 2021 Jan 25. doi: 10.1164/rccm.202008-3266.
    PubMed     Abstract available


  101. CALHOUN WJ, Villasante-Tezanos A
    Response to Parental Triamcinolone in Severe Asthma: A Useful Induced Phenotype for Clinicians?
    Am J Respir Crit Care Med. 2021 Jan 15. doi: 10.1164/rccm.202012-4485.
    PubMed    


  102. VOZORIS NT
    Opioids for Dyspnea in Chronic Obstructive Pulmonary Disease: Short on the Details.
    Am J Respir Crit Care Med. 2021;203:266-267.
    PubMed    


  103. MAMMEN MJ, Charbek E, Alexander PE, Nici L, et al
    Reply to Vozoris: Opioids for Dyspnea in Chronic Obstructive Pulmonary Disease: Short on the Details.
    Am J Respir Crit Care Med. 2021;203:267-269.
    PubMed    


  104. RIZI RR, Hamedani H, Cereda M
    In Chronic Obstructive Pulmonary Disease Progression, Is It Airway Narrowing or Airway Loss?
    Am J Respir Crit Care Med. 2021;203:154-155.
    PubMed    


  105. BODDULURI S, Kizhakke Puliyakote A, Nakhmani A, Charbonnier JP, et al
    Computed Tomography-based Airway Surface Area-to-Volume Ratio for Phenotyping Airway Remodeling in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:185-191.
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  106. CAO X, Bradley TD, Bhatawadekar SA, Saha S, et al
    Effect of Simulated Obstructive Apnea on Thoracic Fluid Volume and Airway Narrowing in Asthma.
    Am J Respir Crit Care Med. 2021 Jan 11. doi: 10.1164/rccm.202012-4321.
    PubMed    


  107. GOORSENBERG AWM, Annema JT, Bonta PI
    Reply to Svenningsen et al.: Eosinophilia and Response to Bronchial Thermoplasty.
    Am J Respir Crit Care Med. 2021;203:148-149.
    PubMed    


  108. SVENNINGSEN S, Cox G, Nair P
    Eosinophilia and Response to Bronchial Thermoplasty.
    Am J Respir Crit Care Med. 2021;203:148.
    PubMed    


  109. WANG CY, Lai CC
    The Role of Eosinophils during the Withdrawal of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:144-145.
    PubMed    


  110. HAN MK, Lipson DA, Singh D, Martinez FJ, et al
    Reply to Wang and Lai: The Role of Eosinophils during the Withdrawal of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2021;203:145-148.
    PubMed    


  111. INOUE KI, Sagawa T, Takano H
    Role of IL-6 in Severe Inflammation.
    Am J Respir Crit Care Med. 2021;203:140-141.
    PubMed    


  112. BORCZUK AC
    Therapeutic Interception of Early Lung Adenocarcinoma Progression: Not Just How, but When?
    Am J Respir Crit Care Med. 2021;203:8-9.
    PubMed    


  113. CASAS-RECASENS S, Noell G, Mendoza N, Lopez-Giraldo A, et al
    Lung DNA Methylation in Chronic Obstructive Pulmonary Disease: Relationship with Smoking Status and Airflow Limitation Severity.
    Am J Respir Crit Care Med. 2021;203:129-134.
    PubMed    


  114. TREEKITKARNMONGKOL W, Hassane M, Sinjab A, Chang K, et al
    Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development.
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    December 2020
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    Severe Adult Asthmas: Integrating Clinical Features, Biology and Therapeutics to Improve Outcomes.
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  116. PETERS MC, Fahy JV
    Erratum: COVID-19-related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids.
    Am J Respir Crit Care Med. 2020;202:1744-1746.
    PubMed    


  117. TURNER S
    Birth Cohort Studies: Their Next Coming of Age.
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    Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate to Severe Asthma.
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  119. KRISHNAN JA, Cloutier MM, Schatz M
    National Asthma Education and Prevention Program 2020 Guideline Update: Where Do We Go From Here?
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    November 2020
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    A Potential New Treatment Option for Asthma in the Setting of Obesity or Insulin Resistance?
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    PubMed    


  121. BOULET LP, Godbout K
    Oral Corticosteroids Tapering in Severe Asthma.
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    PubMed    


  122. NICI L, Aaron SD
    Reply to Mahler et al.: Pharmacotherapy for Chronic Obstructive Pulmonary Disease: Molecules and Delivery Are Equally Important.
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    PubMed    


  123. MAHLER DA, Ohar JA, Ferguson GT, Donohue JF, et al
    Pharmacotherapy for Chronic Obstructive Pulmonary Disease: Molecules and Delivery Are Equally Important.
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    Home Oxygen Therapy for Adults with Chronic Lung Disease. An Official American Thoracic Society Clinical Practice Guideline.
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  125. HALVORSEN T, Clemm HSH, Vollsaeter M, Roksund OD, et al
    Conundrums of Exercise-related Breathing Problems. Epiglottic, Laryngeal, or Bronchial Obstruction?
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    PubMed    


  126. DUNICAN EM, Elicker BM, Henry T, Gierada DS, et al
    Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers.
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  127. SHIN S, Bai L, Burnett RT, Kwong JC, et al
    Air Pollution as a Risk Factor for Incident COPD and Asthma: 15-Year Population-Based Cohort Study.
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  128. HALPIN DMG, Criner GJ, Papi A, Singh D, et al
    Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: The 2020 GOLD Science Committee Report on COVID-19 & COPD.
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  129. SOCKRIDER M, Fussner L
    What Is Asthma?
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    PubMed    


  130. CALVERLEY P
    Angels Dancing on the Tip of a Needle: Interpreting Clinical Trials in Chronic Obstructive Pulmonary Disease.
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    PubMed    


  131. SUISSA S
    Inhaled Corticosteroid Withdrawal in Chronic Obstructive Pulmonary Disease: Can IMPACT Help?
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    PubMed    


  132. GUPTA N, Bleesing JH, McCormack FX
    Successful Response to Treatment with Sirolimus in Pulmonary Sarcoidosis.
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    PubMed    


  133. PETERS MC, Fahy JV, Denlinger LC
    Reply to Nannini and to Lipworth et al.
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    PubMed    


  134. NANNINI LJ
    Short-Acting beta2-Agonist Use Could Be a Confounding Factor for Interpreting Increased IL-6.
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  135. HAN MK, Criner GJ, Dransfield MT, Halpin DMG, et al
    The Effect of Inhaled Corticosteroid Withdrawal and Baseline Inhaled Treatment on Exacerbations in the IMPACT Study. A Randomized, Double-Blind, Multicenter Clinical Trial.
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    October 2020
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    Expert Consensus on the Tapering of Oral Corticosteroids for the Treatment of Asthma: A Delphi Study.
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  137. RABY BA, Weiss ST
    Diversity and the Splice of Life: Mapping the 17q12-21.1 Locus for Variants Associated with Early-onset Asthma in African Americans.
    Am J Respir Crit Care Med. 2020 Oct 27. doi: 10.1164/rccm.202010-3802.
    PubMed    


  138. MILLER A, Goldring RM, Berger KI
    Airway Disease Presenting as Restrictive Impairment.
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    PubMed    


  139. EDDY RL, Parraga G
    Reply to Miller et al.: Airway Disease Presenting as Restrictive Impairment.
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    PubMed    


  140. SKEVAKI C, Weckmann M
    Activation of Group 2 Innate Lymphoid Cells via TL1A/DR3. A Solution to Corticosteroid Resistance?
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    PubMed    


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    Asthma Exacerbations in Type 2 Diabetics with Asthma on Glucagon-like Peptide-1 Receptor Agonists.
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  142. BAHMER T
    Daily, Once-Weekly or No Asthma Controller Therapy At All: The Annoying Issue with Disease Remission in Clinical Asthma Trials.
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    PubMed    


  143. HODSON E, Ratcliffe P
    Endothelial Oxygen Sensing in Alveolar Maintenance.
    Am J Respir Crit Care Med. 2020;202:917-919.
    PubMed    


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    Smoking Pattern in Men and Women: A Possible Contributor to Sex Differences in Smoke-related Lung Diseases.
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    PubMed    


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    Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth.
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    September 2020
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    Don't Forget About Facilitatory Effects of Corticosteroids on beta-2 adrenoceptors in Acute Asthma.
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  147. MORAN AM, Ramakrishnan S, Borg CA, Connolly CM, et al
    Reply to: Don't Forget About Facilitatory Effects of Corticosteroids on beta-2 adrenoceptors in Acute Asthma.
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    PubMed    


  148. GUI H, Levin AM, Hu D, Sleiman P, et al
    Mapping the 17q12-21.1 Locus for Variants Associated with Early-onset Asthma in African Americans.
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  149. SHAH PL, Orton C
    Epithelial Resurfacing: The Bronchial Skin Peel.
    Am J Respir Crit Care Med. 2020;202:641-642.
    PubMed    


  150. CALVERLEY PMA
    Defining Airflow Obstruction: More Data, Further Clarity.
    Am J Respir Crit Care Med. 2020;202:649-650.
    PubMed    


  151. JANAUDIS-FERREIRA T, Ross B, Bourbeau J
    One Step at a Time: A Phased Approach to Behavioral Treatment Development in Pulmonary Rehabilitation.
    Am J Respir Crit Care Med. 2020;202:774-775.
    PubMed    


  152. MEHMOOD M
    Cardiovascular and Chronic Obstructive Pulmonary Disease Therapeutics: Two Paths, One Destination?
    Am J Respir Crit Care Med. 2020;202:779-780.
    PubMed    


  153. PAVORD ID
    Blood Eosinophil-directed Management of Airway Disease. The Past, Present, and Future.
    Am J Respir Crit Care Med. 2020;202:637-639.
    PubMed    


  154. VALIPOUR A, Fernandez-Bussy S, Ing AJ, Steinfort DP, et al
    Bronchial Rheoplasty for Treatment of Chronic Bronchitis. Twelve-Month Results from a Multicenter Clinical Trial.
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    Exercise Tolerance according to the Definition of Airflow Obstruction in Smokers.
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  156. SINGH D, Bafadhel M, Brightling CE, Sciurba FC, et al
    Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2020;202:660-671.
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    August 2020
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    It's Complicated: Lung Dendritic Cells in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2020;202:479-481.
    PubMed    


  158. SETHI S, Aaron SD
    Antibiotic Retreatment for Acute Exacerbations of Chronic Obstructive Pulmonary Disease.
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    PubMed    


  159. MACREA M, Oczkowski S, Rochwerg B, Branson RD, et al
    Long-Term Noninvasive Ventilation in Chronic Stable Hypercapnic Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline.
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    Single-Session Bronchial Thermoplasty Guided by (129)Xe Magnetic Resonance Imaging. A Pilot Randomized Controlled Clinical Trial.
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  161. TODD JL, Neely ML, Kopetskie H, Sever ML, et al
    Risk Factors for Acute Rejection in the First Year after Lung Transplant. A Multicenter Study.
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    Targeted Retreatment of Incompletely Recovered Chronic Obstructive Pulmonary Disease Exacerbations with Ciprofloxacin. A Double-Blind, Randomized, Placebo-controlled, Multicenter, Phase III Clinical Trial.
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    Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease.
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    Update in Chronic Obstructive Pulmonary Disease 2019.
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    Metagenomics Reveals a Core Macrolide Resistome Related to Microbiota in Chronic Respiratory Disease.
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    Respiratory and Cardiovascular Outcomes in Survivors of Extremely Preterm Birth at 19 Years.
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    July 2020
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    Point-Of-Care Spirometry Identifies High-Risk Individuals Excluded from Lung Cancer Screening.
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    Clarifying the Risk of Lung Disease in SZ Alpha-1 Antitrypsin Deficiency.
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