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Articles published in Am J Respir Cell Mol Biol

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Single Articles


    September 2026
  1. XIE Y, Abel PW, Xing T, Zhong N, et al
    Pirfenidone and its derivative: novel bronchodilators and leukocyte airway inflammation inhibitors.
    Am J Respir Cell Mol Biol. 2026;74:1189-1203.
    PubMed     Abstract available


  2. WILLIAMS KR, Fryer AD, Jacoby DB, Nie Z, et al
    Heavy moms, wheezy kids: how maternal obesity harms breathing in offspring.
    Am J Respir Cell Mol Biol. 2026;74:1170-1181.
    PubMed     Abstract available


    August 2026
  3. SUNA R, Pyoa S, Warda E, Dunberrya S, et al
    Poly I:C-induced monocyte-macrophages alleviate type 2 immunopathology in a murine asthma model.
    Am J Respir Cell Mol Biol. 2026 Aug 19:aanag169. doi: 10.1093.
    PubMed     Abstract available


  4. PENN RB
    GPCR Biology-Informed Drug Discovery in Asthma.
    Am J Respir Cell Mol Biol. 2026 Aug 14:aanag168. doi: 10.1093.
    PubMed     Abstract available


  5. PRAKASH YS
    Blast These Dying Fibroblasts in Asthma.
    Am J Respir Cell Mol Biol. 2026 Aug 8:aanag160. doi: 10.1093.
    PubMed    


    June 2026

  6. Correction to: Sex-Specific Perinatal Nicotine-Induced Asthma in Rat Offspring.
    Am J Respir Cell Mol Biol. 2026 Jun 25:aanag125. doi: 10.1093.
    PubMed    


  7. SHEMESH A, Carter S, Hays SR, Singer JP, et al
    Circulating B7H6 is associated with reduced NKp30 receptor expression and improved lung transplant recipient survival.
    Am J Respir Cell Mol Biol. 2026;74:741-754.
    PubMed     Abstract available


    May 2026
  8. BORKAR NA, Halayko AJ
    Pirfenidone for asthma? What to do when standard therapies fail.
    Am J Respir Cell Mol Biol. 2026 May 11:aanag103. doi: 10.1093.
    PubMed    


  9. WHITEHEAD GS, Nakano K, Wilkinson CL, Patterson AM, et al
    Urokinase plasminogen activator receptor attenuates allergen-induced eosinophil migration and airway hyperresponsiveness.
    Am J Respir Cell Mol Biol. 2026;74:690-703.
    PubMed     Abstract available


    April 2026
  10. ZHANG D, Liu W, Wang T, Dong L, et al
    Asthmatic Pulmonary Fibroblasts Aggravate Airway Inflammation Through FKBP5-Dependent Necroptosis.
    Am J Respir Cell Mol Biol. 2026 Apr 15:aanag080. doi: 10.1093.
    PubMed     Abstract available


  11. LV B, Jiang M, Zhang G, Guo D, et al
    Single cell omics identify an anti-inflammatory niche in macrophages of mild to moderate chronic obstructive pulmonary disease.
    Am J Respir Cell Mol Biol. 2026;74:534-546.
    PubMed     Abstract available


  12. TASHIRO H, Kurihara Y, Kuwahara Y, Konomi Y, et al
    Thymic stromal lymphopoietin promotes ozone-induced inflammation in the airway.
    Am J Respir Cell Mol Biol. 2026;74:497-517.
    PubMed     Abstract available


    March 2026
  13. BORKAR NA, Pfeffer-Kleemann DA, Hamrick SK, Koloko Ngassie ML, et al
    Piezo1 Mediates Stretch-Induced Wnt/beta-Catenin Signaling and ECM Remodeling in Aging Asthmatic Airway Smooth Muscle.
    Am J Respir Cell Mol Biol. 2026 Mar 25:aanag058. doi: 10.1093.
    PubMed     Abstract available


  14. WALTS AD, Smith L, Daniels I, Marozkina N, et al
    Dehydroepiandrosterone increases airway epithelial cell pH in asthma patients.
    Am J Respir Cell Mol Biol. 2026 Mar 24:aanag049. doi: 10.1093.
    PubMed    


    February 2026
  15. REZA MI, Tandberg C, Kumar A, Balraj P, et al
    AhR activation inhibits DRP1-induced mitochondrial fission in airway smooth muscle during asthma.
    Am J Respir Cell Mol Biol. 2026 Feb 21:aanag019. doi: 10.1093.
    PubMed     Abstract available


    January 2026
  16. SAKANO K, Sakano Y, Hurrell BP, Kazemi MH, et al
    Targeting CD48 Ameliorates ILC2-mediated Airway Hyperreactivity by Disrupting the PKCbeta Pathway.
    Am J Respir Cell Mol Biol. 2026;74:65-79.
    PubMed     Abstract available


    December 2025
  17. GUO-PARKE H, Cappa O, Linden DA, Barksby BS, et al
    IFN-Mediated Bronchial Epithelium Cellular Senescence in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2025;73:871-883.
    PubMed     Abstract available


  18. LUO M, Zhang X, Guo J, Gu R, et al
    Piezo1 Agonist Yoda1 Induces Rapid Relaxation in Cultured Airway Smooth Muscle Cells and Bronchodilation in Mouse Models.
    Am J Respir Cell Mol Biol. 2025;73:849-858.
    PubMed     Abstract available


  19. VAN DER KOOG L, Wu X, Nugraha DF, Ravi A, et al
    Pulmonary Microvascular Endothelial Cells Support Alveolar Epithelial Growth via Bone Morphogenetic Protein 6 Secretion.
    Am J Respir Cell Mol Biol. 2025;73:920-937.
    PubMed     Abstract available


    October 2025
  20. SHARMA P
    Sex-based Immune and Genetic Mechanisms in Asthma: A Shift Toward Precision Medicine?
    Am J Respir Cell Mol Biol. 2025 Oct 22. doi: 10.1165/rcmb.2025-0423.
    PubMed    


  21. KONG W, Huang C, Zhao L, Chen G, et al
    SERPINB10 Promotes Neutrophilic Airway Inflammation in Asthma.
    Am J Respir Cell Mol Biol. 2025 Oct 10. doi: 10.1165/rcmb.2024-0580.
    PubMed     Abstract available


  22. NAYAK AP
    E3 Ubiquitin Ligases and Asthma Relief.
    Am J Respir Cell Mol Biol. 2025 Oct 10. doi: 10.1165/rcmb.2025-0532.
    PubMed    


  23. SHAH SD, Deshpande DA
    Biased Orthosteric Agonism and Allosteric Modulation: Emerging Strategies for Developing New Class of beta-Agonists for Obstructive Airway Diseases.
    Am J Respir Cell Mol Biol. 2025;73:489-499.
    PubMed     Abstract available


  24. THOMAS BJ, Kan-O K, Gantier MP, Simpson I, et al
    Pirfenidone Mitigates Transforming Growth Factor-beta-induced Inflammation after Viral Infection.
    Am J Respir Cell Mol Biol. 2025;73:545-558.
    PubMed     Abstract available


  25. DUPIN I, Henrot P, Maurat E, Abohalaka R, et al
    CXCR4 Blockade Alleviates Pulmonary and Cardiac Outcomes in Early Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2025;73:530-544.
    PubMed     Abstract available


    September 2025
  26. GUPTA A, Dahlin A, Macario A, Gally F, et al
    Functional Variant Discovery Identifies a Novel Genetic Link Between SPRY2, Wood Smoke, and Asthma.
    Am J Respir Cell Mol Biol. 2025 Sep 29. doi: 10.1165/rcmb.2024-0587.
    PubMed     Abstract available


  27. WANG S, Ruan J, Yan P, Ying L, et al
    IRAK2 Ubiquitination Mediated by PELI1 Impairs Airway Epithelial Function and Accelerates Pediatric Asthma.
    Am J Respir Cell Mol Biol. 2025 Sep 23. doi: 10.1165/rcmb.2024-0573.
    PubMed     Abstract available


  28. REITER BFE, Bordag N, Schnoegl D, Delbeck M, et al
    The Acrolein-Lipopolysaccharide Mouse Model for Frequent Exacerbations in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2025;73:343-352.
    PubMed     Abstract available


    August 2025
  29. DEVULDER JV, Baker JR, Fenwick PS, Odqvist L, et al
    Chronic Obstructive Pulmonary Disease Airway Epithelial Cell-derived Extracellular Vesicles Spread Cellular Senescence via MicroRNA-34a.
    Am J Respir Cell Mol Biol. 2025;73:210-220.
    PubMed     Abstract available


    July 2025
  30. GERDAY S, Schleich F, Sabbe M, Moermans C, et al
    Transcriptomics in T2-High Severe Asthmatics Treated with Biologics: Comparison Between Anti-IgE, Anti-IL-5 and Anti-IL-5R-Targeted Treatments.
    Am J Respir Cell Mol Biol. 2025 Jul 23. doi: 10.1165/rcmb.2025-0188.
    PubMed    


  31. GIRARD RA, Karmouty-Quintana H
    When Lipid Mediators Keep Lungs Whole: A Spontaneous, Female-Predominant Model of Emphysema.
    Am J Respir Cell Mol Biol. 2025 Jul 2. doi: 10.1165/rcmb.2025-0349.
    PubMed    


  32. SILVEYRA P
    "Scripts" Don't Lie: Sex and Age Shape Blood Immune Gene Expression in Asthma.
    Am J Respir Cell Mol Biol. 2025 Jul 2. doi: 10.1165/rcmb.2025-0371.
    PubMed    


  33. MAKRINIOTI H, Camargo CA Jr, Zhu Z
    Unraveling the Molecular Complexity of Asthma: Insights from a Multicohort Transcriptome Study.
    Am J Respir Cell Mol Biol. 2025;73:6-8.
    PubMed    


  34. MWASE C, Schworer SA, Gilmore RC, Khan F, et al
    TGF-beta Receptor-dependent Tissue Factor Release and Proteomic Profiling of Extracellular Vesicles from Mechanically Compressed Human Bronchial Epithelial Cells.
    Am J Respir Cell Mol Biol. 2025;73:88-95.
    PubMed     Abstract available


    June 2025
  35. ISHII Y, Makita K, Fujii U, Nakada E, et al
    Leukotriene C(4) Synthase Deficiency Causes Spontaneous Emphysema in Female Mice.
    Am J Respir Cell Mol Biol. 2025 Jun 30. doi: 10.1165/rcmb.2024-0260.
    PubMed     Abstract available


  36. KAY S, Rajeevan H, Son M, Kwah J, et al
    Sex-biased Gene Expression Underlies Immune Dysfunction in Asthma.
    Am J Respir Cell Mol Biol. 2025 Jun 30. doi: 10.1165/rcmb.2024-0565.
    PubMed     Abstract available


  37. BOWLES AH, Warren KJ
    Regulating Neutrophilic Asthma with IL-33: Maybe We Shouldn't Block IL-33 after All?
    Am J Respir Cell Mol Biol. 2025 Jun 4. doi: 10.1165/rcmb.2025-0230.
    PubMed    


    May 2025
  38. SUI J, Johnson AR, Kapellos TS, Shiva S, et al
    ANT1 Deficiency Impairs Macrophage Metabolism and Migration, Protecting Against Emphysema in COPD.
    Am J Respir Cell Mol Biol. 2025 May 29. doi: 10.1165/rcmb.2024-0469.
    PubMed     Abstract available


  39. DECUZZI NL, Oberbauer D, Chmiel KJ, Pargett M, et al
    Spatiotemporal Clusters of Extracellular Signal-Regulated Kinase Activity Coordinate Cytokine-induced Inflammatory Responses in Human Airway Epithelial Cells.
    Am J Respir Cell Mol Biol. 2025;72:520-532.
    PubMed     Abstract available


  40. YANG Y, Shen W, Zhang Z, Dai Y, et al
    FSP1 Acts in Parallel with GPX4 to Inhibit Ferroptosis in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2025;72:551-562.
    PubMed     Abstract available


    April 2025
  41. PADRA M, Bergwik J, Adler A, Marcoux G, et al
    Tartrate-Resistant Acid Phosphatase 5 (TRAP5) Promotes Eosinophil Migration During Allergic Asthma.
    Am J Respir Cell Mol Biol. 2025 Apr 2. doi: 10.1165/rcmb.2024-0304.
    PubMed     Abstract available


  42. HARA N, Raclawska DS, Morgan LE, NeeDell JC, et al
    Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction.
    Am J Respir Cell Mol Biol. 2025;72:408-417.
    PubMed     Abstract available


  43. XING Y, Nho Y, Lawson K, Zhu Y, et al
    MrgprC11(+) Jugular Neurons Control Airway Hyperresponsiveness in Allergic Airway Inflammation.
    Am J Respir Cell Mol Biol. 2025;72:393-407.
    PubMed     Abstract available


    March 2025
  44. ZHANG Z, Cai T, Zhang X, Li X, et al
    Esrrg Inhibition Protects Against PM2.5-induced Asthma Aggravation by Reducing Pde3b.
    Am J Respir Cell Mol Biol. 2025 Mar 28. doi: 10.1165/rcmb.2024-0461.
    PubMed     Abstract available


  45. RAY JL, Walum J, Jelic D, Barnes R, et al
    scRNAseq Identifies Unique Macrophage Population in Mouse Model of Ozone Induced Asthma Exacerbation.
    Am J Respir Cell Mol Biol. 2025 Mar 19. doi: 10.1165/rcmb.2024-0358.
    PubMed     Abstract available


  46. BORKAR NA, Thompson MA, Kelley B, Shiferaw BT, et al
    Nicotine-Induced Endoplasmic Reticulum Stress and Airway Smooth Muscle Cell Proliferation Is Mediated by alpha7nAChR and Chaperones-RIC-3 and TMEM35.
    Am J Respir Cell Mol Biol. 2025;72:297-307.
    PubMed     Abstract available


    February 2025
  47. YU Q, Zhou Y, Wang J, Zhang M, et al
    TFEB SUMOylation in Airway Epithelial Cells Impairs Lysosomal Biogenesis to Promote Asthma Development.
    Am J Respir Cell Mol Biol. 2025 Feb 25. doi: 10.1165/rcmb.2024-0191.
    PubMed     Abstract available


  48. OGAWA T, Maki Y, Takahashi S, Ono T, et al
    Airway Epithelium-derived CXCL14 Promotes Eosinophil Accumulation in Allergic Airway Inflammation.
    Am J Respir Cell Mol Biol. 2025;72:145-157.
    PubMed     Abstract available


    January 2025
  49. EL-HUSSEINI ZW, Karp T, Lan A, Gillett TE, et al
    Improved Annotation of Asthma Gene Variants with Cell Type Deconvolution of Nasal and Lung Expression-Quantitative Trait Loci.
    Am J Respir Cell Mol Biol. 2025 Jan 21. doi: 10.1165/rcmb.2024-0251.
    PubMed     Abstract available


  50. PUTHUSSERI B, Bhagavath AK, Korir D, Shetty R, et al
    CSP7 Protects Alveolar Epithelial Cells by Targeting p53-Fibrinolytic Pathways During Lung Injuries.
    Am J Respir Cell Mol Biol. 2025;72:97-108.
    PubMed     Abstract available


  51. LOPES-RAMOS CM, Shutta KH, Ryu MH, Huang Y, et al
    Sex-Biased Regulation of Extracellular Matrix Genes in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2025;72:72-81.
    PubMed     Abstract available


    December 2024
  52. LEE I, Ganesan A, Kalesinskas L, Zheng H, et al
    Multicohort Analysis of Bronchial Epithelial Cell Expression in Healthy Subjects and Patients with Asthma Reveals Four Clinically Distinct Clusters.
    Am J Respir Cell Mol Biol. 2024 Dec 19. doi: 10.1165/rcmb.2024-0125.
    PubMed     Abstract available


  53. PINCUS AB, Pierce AB, Kappel N, Lebold KM, et al
    Parasympathetic Airway Hyperreactivity Is Enhanced in Acute but Not Chronic Eosinophilic Asthma Mouse Models.
    Am J Respir Cell Mol Biol. 2024 Dec 3. doi: 10.1165/rcmb.2024-0360.
    PubMed     Abstract available


  54. CHOUDHARY I, Lamichhane R, Singamsetty D, Vo T, et al
    Cell-Specific Contribution of IL-4 Receptor alpha Signaling Shapes the Overall Manifestation of Allergic Airway Disease.
    Am J Respir Cell Mol Biol. 2024;71:702-717.
    PubMed     Abstract available


    November 2024
  55. JANNU AK, Penn RB
    Channeling Relaxation through Multiple Means: TMEM16A Antagonism for Asthma.
    Am J Respir Cell Mol Biol. 2024 Nov 26. doi: 10.1165/rcmb.2024-0521.
    PubMed    


  56. CORTESELLI E, Alexis N
    Cough Variant Asthma: The Asthma Phenotype No One Coughs About.
    Am J Respir Cell Mol Biol. 2024 Nov 20. doi: 10.1165/rcmb.2024-0517.
    PubMed    


  57. WU A, Kuforiji A, Zhang Y, Xu D, et al
    TMEM16A Antagonism: Therapeutic Potential with Desensitization of beta-agonist Responsiveness in Asthma.
    Am J Respir Cell Mol Biol. 2024 Nov 19. doi: 10.1165/rcmb.2024-0231.
    PubMed     Abstract available


    October 2024
  58. CHEN Z, Jin K, Fang Z, Huang K, et al
    Sputum Metabolomic Signature and Dynamic Change of Cough Variant Asthma.
    Am J Respir Cell Mol Biol. 2024 Oct 11. doi: 10.1165/rcmb.2024-0219.
    PubMed     Abstract available


  59. WANG R, Liao G, Tang DD
    TET1 Regulates Nestin Expression and Human Airway Smooth Muscle Proliferation.
    Am J Respir Cell Mol Biol. 2024;71:420-429.
    PubMed     Abstract available


    September 2024
  60. CURTISS ML, Rothman PB
    Piecing Together the Role of IL-4 Receptor Alpha in Allergic Asthma One Cell at a Time.
    Am J Respir Cell Mol Biol. 2024 Sep 18. doi: 10.1165/rcmb.2024-0309.
    PubMed    


    August 2024
  61. GERBER AN
    Airway Smooth Muscle Dysfunction in Asthma: Releasing the Anchor.
    Am J Respir Cell Mol Biol. 2024 Aug 22. doi: 10.1165/rcmb.2024-0374.
    PubMed    


  62. PARK JA
    E-cad! That's a Big Switch from Epithelial Membrane Protein to Asthma Mediator.
    Am J Respir Cell Mol Biol. 2024 Aug 1. doi: 10.1165/rcmb.2024-0310.
    PubMed    


  63. WU D, Zhang X, Zimmerly KM, Wang R, et al
    Unconventional Activation of IRE1 Enhances Th17 Responses and Promotes Airway Neutrophilia.
    Am J Respir Cell Mol Biol. 2024;71:169-181.
    PubMed     Abstract available


    July 2024
  64. TANG H, Chen Z, Gan S, Guo Y, et al
    Soluble E-Cadherin Contributes to Airway Inflammation in Severe Asthma.
    Am J Respir Cell Mol Biol. 2024 Jul 30. doi: 10.1165/rcmb.2024-0133.
    PubMed     Abstract available


  65. XU Y, Li M, Bai L
    Pulmonary Epithelium Cell Fate Determination: COPD, Lung Cancer, or Both.
    Am J Respir Cell Mol Biol. 2024 Jul 30. doi: 10.1165/rcmb.2023-0448.
    PubMed     Abstract available


  66. KLEIN M, Gagnon PA, Salem M, Rouabhia M, et al
    MiR-155-5p Differentially Regulates IL-13Ralpha1 and IL-13Ralpha2 Expression and Signalling, Driving Abnormal Lung Epithelial Cell Phenotype in Severe Asthma.
    Am J Respir Cell Mol Biol. 2024 Jul 25. doi: 10.1165/rcmb.2024-0089.
    PubMed     Abstract available


  67. HUANG Q, Gu Y, Wu J, Zhan Y, et al
    DACH1 Attenuates Airway Inflammation in Chronic Obstructive Pulmonary Disease by Activating NRF2 Signaling.
    Am J Respir Cell Mol Biol. 2024;71:121-132.
    PubMed     Abstract available


    June 2024
  68. LEGRAND C, Vanneste D, Hego A, Sabatel C, et al
    Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3(+) Regulatory T Cells.
    Am J Respir Cell Mol Biol. 2024;70:446-456.
    PubMed     Abstract available


    May 2024
  69. SEOW CY
    SRF Overexpression, A Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma.
    Am J Respir Cell Mol Biol. 2024 May 2. doi: 10.1165/rcmb.2024-0168.
    PubMed    


  70. DONOVAN C, Thorpe AE, Gomez HM, Carroll OR, et al
    The GPR84 Antagonist GLPG1205 Reduces Features of Disease in Experimental Severe Asthma.
    Am J Respir Cell Mol Biol. 2024;70:424-427.
    PubMed    


  71. KHALENKOW D, Brandsma CA, Timens W, Choy DF, et al
    Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2024;70:414-423.
    PubMed     Abstract available


    April 2024
  72. SHARMA S, Gerber AN, Kraft M, Wenzel SE, et al
    Asthma Pathogenesis: Phenotypes, Therapies and Gaps. Summary of the Aspen Lung Conference 2023.
    Am J Respir Cell Mol Biol. 2024 Apr 18. doi: 10.1165/rcmb.2024-0082.
    PubMed     Abstract available


  73. HICKMAN E, Alexis NE, Rager JE, Jaspers I, et al
    Airway Proteotypes of E-Cigarette Users Overlap with Those Found in Asthmatics.
    Am J Respir Cell Mol Biol. 2024;70:326-328.
    PubMed    


    March 2024
  74. FUENTES-MATEOS R, Gosens R
    Disinherit your Descendants by Rewriting the Chronic Pulmonary Obstructive Disease Epigenetic Script.
    Am J Respir Cell Mol Biol. 2024;70:153-154.
    PubMed    


  75. YEUNG-LUK BH, Wally A, Swaby C, Jauregui S, et al
    Epigenetic Reprogramming Drives Epithelial Disruption in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2024;70:165-177.
    PubMed     Abstract available


    November 2023
  76. TRUONG LN, Santos EW, Zheng YM, Wang YX, et al
    Rieske Iron-Sulfur Protein Mediates Pulmonary Hypertension Following Nicotine/Hypoxia Co-Exposure.
    Am J Respir Cell Mol Biol. 2023 Nov 29. doi: 10.1165/rcmb.2023-0181.
    PubMed     Abstract available


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