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  Obstructive Lung Diseases

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Articles published in Am J Respir Cell Mol Biol

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    December 2021
  1. LI YK, Zhang XX, Yang Y, Gao J, et al
    Convergent Evidence Supports TH2LCRR as a Novel Asthma Susceptibility Gene.
    Am J Respir Cell Mol Biol. 2021 Dec 1. doi: 10.1165/rcmb.2020-0481.
    PubMed     Abstract available


  2. SMITH GJ, Tovar A, McFadden K, Moran TP, et al
    A Murine Model of Ozone-induced Nonatopic Asthma from the Collaborative Cross.
    Am J Respir Cell Mol Biol. 2021;65:672-674.
    PubMed    


    November 2021
  3. WRENNALL JA, Ahmad S, Worthington EN, Wu T, et al
    A SPLUNC1 Peptidomimetic Inhibits Orai1 and Reduces Inflammation in a Murine Allergic Asthma Model.
    Am J Respir Cell Mol Biol. 2021 Nov 22. doi: 10.1165/rcmb.2020-0452.
    PubMed     Abstract available


  4. TAM JKC, Tran T
    Plk1 in Asthma - Ready for Primetime?
    Am J Respir Cell Mol Biol. 2021 Nov 8. doi: 10.1165/rcmb.2021-0425.
    PubMed    


  5. CHEN Q, Heijink IH, de Vries M
    Connecting GWAS Susceptibility Genes in COPD: Do We Need to Consider TGF-beta2?
    Am J Respir Cell Mol Biol. 2021;65:468-470.
    PubMed    


  6. TIGHE RM, Patel SM
    Human Immunodeficiency Virus, Smoking, and Chronic Obstructive Pulmonary Disease: A Case of T Cells Stuck in the Wrong Place?
    Am J Respir Cell Mol Biol. 2021;65:464-465.
    PubMed    


  7. CORLEIS B, Cho JL, Gates SJ, Linder AH, et al
    Smoking and Human Immunodeficiency Virus 1 Infection Promote Retention of CD8(+) T Cells in the Airway Mucosa.
    Am J Respir Cell Mol Biol. 2021;65:513-520.
    PubMed     Abstract available


  8. GONG L, Bates S, Li J, Qiao D, et al
    Connecting COPD GWAS Genes: FAM13A Controls TGFbeta2 Secretion by Modulating AP-3 Transport.
    Am J Respir Cell Mol Biol. 2021;65:532-543.
    PubMed     Abstract available


    September 2021
  9. SCHUMACKER PT
    Mitochondrial Succinate Dehydrogenase in Chronic Obstructive Pulmonary Disease: Is Complex II Too Complex?
    Am J Respir Cell Mol Biol. 2021;65:231-232.
    PubMed    


  10. OKUZUMI S, Miyata J, Kabata H, Mochimaru T, et al
    TLR7 Agonist Suppresses Group 2 Innate Lymphoid Cell-mediated Inflammation via IL-27-Producing Interstitial Macrophages.
    Am J Respir Cell Mol Biol. 2021;65:309-318.
    PubMed     Abstract available


    August 2021
  11. HEDSTROM U, Oberg L, Vaarala O, Dellgren G, et al
    Impaired Differentiation of Chronic Obstructive Pulmonary Disease Bronchial Epithelial Cells Grown on Bronchial Scaffolds.
    Am J Respir Cell Mol Biol. 2021;65:201-213.
    PubMed     Abstract available


    July 2021
  12. MOSTACO-GUIDOLIN LB, Yang CX, Hackett TL
    Pulmonary Vascular Remodeling Is an Early Feature of Fatal and Nonfatal Asthma.
    Am J Respir Cell Mol Biol. 2021;65:114-118.
    PubMed    


  13. ACUNZO M, Nana-Sinkam P
    Functional Gene Variants in Chronic Obstructive Pulmonary Disease: The Search Continues.
    Am J Respir Cell Mol Biol. 2021;65:8-9.
    PubMed    


  14. SHAYKHIEV R
    Airway Basal Cells in Chronic Obstructive Pulmonary Disease: A Continuum or a Dead End?
    Am J Respir Cell Mol Biol. 2021;65:10-12.
    PubMed    


  15. WIJK SC, Prabhala P, Michalikova B, Sommarin M, et al
    Human Primary Airway Basal Cells Display a Continuum of Molecular Phases from Health to Disease in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2021;65:103-113.
    PubMed     Abstract available


  16. BENWAY CJ, Liu J, Guo F, Du F, et al
    Chromatin Landscapes of Human Lung Cells Predict Potentially Functional Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Variants.
    Am J Respir Cell Mol Biol. 2021;65:92-102.
    PubMed     Abstract available


    June 2021
  17. WRONSKI S, Beinke S, Obernolte H, Belyaev NN, et al
    Rhinovirus-induced Human Lung Tissue Responses Mimic COPD and Asthma Gene Signatures.
    Am J Respir Cell Mol Biol. 2021 Jun 28. doi: 10.1165/rcmb.2020-0337.
    PubMed     Abstract available


  18. TRABER KE, Center DM
    Towards a More Precise Solution to Asthma Therapy.
    Am J Respir Cell Mol Biol. 2021 Jun 21. doi: 10.1165/rcmb.2021-0227.
    PubMed    


  19. DI VINCENZO S, Pace E
    Exploring the Influence of Cigarette Smoke on TROP2 Expression in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2021;64:655-656.
    PubMed    


    May 2021
  20. REDDY KD, Lan A, Boudewijn IM, Rathnayake SNH, et al
    Current-Smoking alters Gene Expression and DNA Methylation in the Nasal Epithelium of Asthmatics.
    Am J Respir Cell Mol Biol. 2021 May 14. doi: 10.1165/rcmb.2020-0553.
    PubMed     Abstract available


  21. XIONG J, Le Y, Rao Y, Zhou L, et al
    RANKL Mediates Muscle Atrophy and Dysfunction in a Cigarette Smoke-induced Model of Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2021;64:617-628.
    PubMed     Abstract available


  22. LI X, Goobie GC, Gregory AD, Kass DJ, et al
    Toll-Interacting Protein in Pulmonary Diseases. Abiding by the Goldilocks Principle.
    Am J Respir Cell Mol Biol. 2021;64:536-546.
    PubMed     Abstract available


    April 2021
  23. BALNIS J, Drake LA, Vincent CE, Korponay TC, et al
    Succinate Dehydrogenase (SDH)-subunit C Regulates Muscle Oxygen Consumption and Fatigability in an Animal Model of Pulmonary Emphysema.
    Am J Respir Cell Mol Biol. 2021 Apr 28. doi: 10.1165/rcmb.2020-0551.
    PubMed     Abstract available


  24. YAO X, Levine SJ
    Scavenger Hunt: SR-B1, Adrenal Insufficiency, IL-17A and Neutrophilic Airway Inflammation in Asthma.
    Am J Respir Cell Mol Biol. 2021 Apr 7. doi: 10.1165/rcmb.2021-0089.
    PubMed    



  25. Retraction: Causation of Cigarette Smoke-induced Emphysema by p-Benzoquinone and Its Prevention by Vitamin C.
    Am J Respir Cell Mol Biol. 2021;64:519.
    PubMed    


  26. DE SANTI C, Greene CM
    Bronchial Epithelial Cell Transcriptomics: A Tool to Monitor and Predict Chronic Obstructive Pulmonary Disease Progression?
    Am J Respir Cell Mol Biol. 2021;64:399-400.
    PubMed    


  27. SAMAHA E, Vierlinger K, Weinhappel W, Godnic-Cvar J, et al
    Expression Profiling Suggests Loss of Surface Integrity and Failure of Regenerative Repair as Major Driving Forces for Chronic Obstructive Pulmonary Disease Progression.
    Am J Respir Cell Mol Biol. 2021;64:441-452.
    PubMed     Abstract available


  28. BODAS M, Moore AR, Subramaniyan B, Georgescu C, et al
    Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells.
    Am J Respir Cell Mol Biol. 2021;64:426-440.
    PubMed     Abstract available


    March 2021
  29. JOHANSSON MW
    Seeing is Believing: Extravascular Platelet Recruitment in Asthma and Allergic Inflammation.
    Am J Respir Cell Mol Biol. 2021 Mar 11. doi: 10.1165/rcmb.2021-0045.
    PubMed    


  30. MANUEL AM, van de Wetering C, MacPherson M, Erickson C, et al
    Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma.
    Am J Respir Cell Mol Biol. 2021 Mar 4. doi: 10.1165/rcmb.2020-0512.
    PubMed     Abstract available


  31. REECE SW, Varikuti S, Kilburg-Basnyat B, Dunigan-Russell K, et al
    Scavenger Receptor BI Attenuates IL-17A-dependent Neutrophilic Inflammation in Asthma.
    Am J Respir Cell Mol Biol. 2021 Mar 1. doi: 10.1165/rcmb.2020-0007.
    PubMed     Abstract available


  32. YAO X, Levine SJ
    The Long and Winding Road from GWAS to Obstructive Lung Disease: Is There a Role for LRP1?
    Am J Respir Cell Mol Biol. 2021;64:279-280.
    PubMed    


    February 2021
  33. SHAH SA, Kanabar V, Riffo-Vasquez Y, Mohamed Z, et al
    Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3.
    Am J Respir Cell Mol Biol. 2021 Feb 8. doi: 10.1165/rcmb.2020-0425.
    PubMed     Abstract available


  34. JUNDI B, Geraghty P
    ADAM17: A Therapeutic Target for Patients with Emphysema?
    Am J Respir Cell Mol Biol. 2021;64:155-157.
    PubMed    


  35. SAFERALI A, Yun JH, Lee S, Chase RP, et al
    Transcriptomic Signature of Asthma-Chronic Obstructive Pulmonary Disease Overlap in Whole Blood.
    Am J Respir Cell Mol Biol. 2021;64:268-271.
    PubMed    


  36. MCCOMBS JE, Kolls JK
    Walking down the "IL": The Newfound Marriage between IL-36 and Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2021;64:153-154.
    PubMed    


  37. KOVACH MA, Che K, Brundin B, Andersson A, et al
    IL-36 Cytokines Promote Inflammation in the Lungs of Long-Term Smokers.
    Am J Respir Cell Mol Biol. 2021;64:173-182.
    PubMed     Abstract available


    January 2021
  38. CHIBA Y, Ando Y, Fujii S, Miyakawa Y, et al
    Downregulation of miR-140-3p Is a Cause of Upregulation of RhoA Protein in Bronchial Smooth Muscle of Murine Experimental Asthma.
    Am J Respir Cell Mol Biol. 2021;64:138-140.
    PubMed    


  39. PERCIER P, De Prins S, Tima G, Beyaert R, et al
    Aspergillus fumigatus Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation through a TLR2/MyD88 Pathway.
    Am J Respir Cell Mol Biol. 2021;64:39-49.
    PubMed     Abstract available


    December 2020
  40. WILLIAMS TC, Jackson DJ, Maltby S, Walton RP, et al
    Rhinovirus-induced CCL17 and CCL22 in Asthma Exacerbations and Differential Regulation by STAT6.
    Am J Respir Cell Mol Biol. 2020 Dec 2. doi: 10.1165/rcmb.2020-0011.
    PubMed     Abstract available



  41. Expression of Concern: Mitochondrial-Targeted Antioxidant Therapy Decreases Transforming Growth Factor-beta-Mediated Collagen Production in a Murine Asthma Model.
    Am J Respir Cell Mol Biol. 2020;63:868.
    PubMed    


  42. VASUDEVAN S, Vasquez JJ, Chen W, Aguilar-Rodriguez B, et al
    Lower PDL1, PDL2, and AXL Expression on Lung Myeloid Cells Suggests Inflammatory Bias in Smoking and Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2020;63:780-793.
    PubMed     Abstract available


    November 2020
  43. SAAD MI, McLeod L, Hodges C, Vlahos R, et al
    ADAM17 Deficiency Protects Against Pulmonary Emphysema.
    Am J Respir Cell Mol Biol. 2020 Nov 12. doi: 10.1165/rcmb.2020-0214.
    PubMed     Abstract available


  44. BONVINI SJ
    Cause or Effect? Stretching to Understand the Inflammatory Role of Elastin Fiber Breakdown in Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2020;63:558-559.
    PubMed    


    September 2020
  45. MURPHY RC, Lai Y, Barrow KA, Hamerman JA, et al
    Effects of Asthma and Human Rhinovirus A16 on the Expression of the SARS-CoV-2 Entry Factors in Human Airway Epithelium.
    Am J Respir Cell Mol Biol. 2020 Sep 18. doi: 10.1165/rcmb.2020-0394.
    PubMed    


  46. TSUTSUMI A, Ozaki M, Chubachi S, Irie H, et al
    Exposure to Cigarette Smoke Enhances the Stemness of Alveolar Type 2 Cells.
    Am J Respir Cell Mol Biol. 2020;63:293-305.
    PubMed     Abstract available


    August 2020
  47. HAIDER SH, Veerappan A, Crowley G, Caraher EJ, et al
    Multiomics of World Trade Center Particulate Matter-induced Persistent Airway Hyperreactivity. Role of Receptor for Advanced Glycation End Products.
    Am J Respir Cell Mol Biol. 2020;63:219-233.
    PubMed     Abstract available


  48. MONTGOMERY MT, Sajuthi SP, Cho SH, Everman JL, et al
    Genome-Wide Analysis Reveals Mucociliary Remodeling of the Nasal Airway Epithelium Induced by Urban PM2.5.
    Am J Respir Cell Mol Biol. 2020;63:172-184.
    PubMed     Abstract available


  49. SCHIFFERS C, Hristova M, Habibovic A, Dustin CM, et al
    The Transient Receptor Potential Channel Vanilloid 1 Is Critical in Innate Airway Epithelial Responses to Protease Allergens.
    Am J Respir Cell Mol Biol. 2020;63:198-208.
    PubMed     Abstract available


    July 2020
  50. LONG ME, Manicone AM
    Loss of C/EBPalpha in Chronic Cigarette Smoke Exposure: A SAD Day for Chronic Obstructive Pulmonary Disease.
    Am J Respir Cell Mol Biol. 2020;63:9-10.
    PubMed    


  51. UENO H, Koya T, Takeuchi H, Tsukioka K, et al
    Cysteinyl Leukotriene Synthesis via Phospholipase A2 Group IV Mediates Exercise-induced Bronchoconstriction and Airway Remodeling.
    Am J Respir Cell Mol Biol. 2020;63:57-66.
    PubMed     Abstract available


  52. CARRER M, Crosby JR, Sun G, Zhao C, et al
    Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-induced Goblet Cell Metaplasia in the Adult Murine Lung.
    Am J Respir Cell Mol Biol. 2020;63:46-56.
    PubMed     Abstract available


  53. YEUNG BHY, Huang J, An SS, Solway J, et al
    Role of Isocitrate Dehydrogenase 2 on DNA Hydroxymethylation in Human Airway Smooth Muscle Cells.
    Am J Respir Cell Mol Biol. 2020;63:36-45.
    PubMed     Abstract available


    June 2020
  54. LIU Y, Bochkov YA, Eickhoff JC, Hu T, et al
    Orosomucoid-like 3 Supports Rhinovirus Replication in Human Epithelial Cells.
    Am J Respir Cell Mol Biol. 2020;62:783-792.
    PubMed     Abstract available


  55. ALSAFADI HN, Uhl FE, Pineda RH, Bailey KE, et al
    Applications and Approaches for Three-Dimensional Precision-Cut Lung Slices. Disease Modeling and Drug Discovery.
    Am J Respir Cell Mol Biol. 2020;62:681-691.
    PubMed     Abstract available


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