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  Otorhinolaryngology

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 22 articles:
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Single Articles


    January 2026
  1. HONG JW, Min H, Kim S, Song HG, et al
    Pharmacological chaperones mitigate noise-induced hearing loss by attenuating sustained PERK activation.
    Proc Natl Acad Sci U S A. 2026;123:e2421591123.
    PubMed     Abstract available


    December 2025
  2. ESMAELPOOR J, Peng T, Jelfs B, Mao D, et al
    Dynamic functional connectivity following cochlear implantation: Predicting speech outcomes and exploring brain network dynamics.
    Proc Natl Acad Sci U S A. 2025;122:e2505086122.
    PubMed     Abstract available


  3. RIAHI Z, Boucher S, Abdi S, Wong Jun Tai F, et al
    Genetics of prelingual isolated deafness and Usher syndrome in the Maghreb and Jordan: Harnessing the potential of homozygosity.
    Proc Natl Acad Sci U S A. 2025;122:e2518445122.
    PubMed     Abstract available


    November 2025
  4. QIU X, Llongueras JP, Yin L, Cunningham C, et al
    LHFPL5 is required for maximal activation of the mechanotransduction channel in cochlear hair cells.
    Proc Natl Acad Sci U S A. 2025;122:e2505627122.
    PubMed     Abstract available


    October 2025
  5. SONG T, Li Q, Lyu Q, Zhao J, et al
    EFCAB10 anchors AK8 to the radial spoke for proper ciliary motility.
    Proc Natl Acad Sci U S A. 2025;122:e2510243122.
    PubMed     Abstract available


    September 2025
  6. WESTERMANN FG, Oken AC, Granith PKE, Marimuthu P, et al
    Subtype-specific structural features of the hearing loss-associated human P2X2 receptor.
    Proc Natl Acad Sci U S A. 2025;122:e2417753122.
    PubMed     Abstract available


  7. LI XJ, Morgan C, Duy PQ, Evsen L, et al
    The RNA-binding protein TRIM71 is essential for hearing in humans and mice and times auditory sensory organ development.
    Proc Natl Acad Sci U S A. 2025;122:e2505811122.
    PubMed     Abstract available


    August 2025
  8. ZHAO Z, Li A, Zhu Y, Cen S, et al
    Blood-labyrinth barrier damage mediated by granzymes from cytotoxic lymphocytes results in hearing loss in systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2025;122:e2423240122.
    PubMed     Abstract available


    June 2025
  9. LIANG C, Zhai TY, Chen J, Fang S, et al
    ATP-gated P2x7 receptors express at type II auditory nerves and required for efferent hearing control and noise protection.
    Proc Natl Acad Sci U S A. 2025;122:e2421995122.
    PubMed     Abstract available


    May 2025
  10. MARTIN M, Bolognesi B
    Massive mutagenesis reveals an incomplete amyloid motif in Bri2 that turns amyloidogenic upon C-terminal extension.
    Proc Natl Acad Sci U S A. 2025;122:e2415521122.
    PubMed     Abstract available


  11. HENNIG M, Bhattacharjee RB, Agarwal I, Alfaifi A, et al
    Inhaled DNAI1 mRNA therapy for treatment of primary ciliary dyskinesia.
    Proc Natl Acad Sci U S A. 2025;122:e2421915122.
    PubMed     Abstract available


    April 2025
  12. SCHNUPP JWH, Buchholz S, Buck AN, Budig H, et al
    Pulse timing dominates binaural hearing with cochlear implants.
    Proc Natl Acad Sci U S A. 2025;122:e2416697122.
    PubMed     Abstract available


    March 2025
  13. BEURG M, Konrad DE, Fettiplace R
    Hair cell apoptosis and deafness in Tmc1 mutations.
    Proc Natl Acad Sci U S A. 2025;122:e2425215122.
    PubMed     Abstract available


  14. XIAO Y, Zhang X, Guo S, Liu Z, et al
    GSDMD-mediated mitochondrial dysfunction in marginal cells: A potential driver of inflammation and stria vascularis damage in CIHL.
    Proc Natl Acad Sci U S A. 2025;122:e2415805122.
    PubMed     Abstract available


    February 2025
  15. LI J, Oh SI, Liu C, Zhao B, et al
    Inhibition of GABARAP or GABARAPL1 prevents aminoglycoside- induced hearing loss.
    Proc Natl Acad Sci U S A. 2025;122:e2416453122.
    PubMed     Abstract available


    December 2024
  16. PATEL A, Pauzuolyte V, Ingham NJ, Leong YC, et al
    Rescue of cochlear vascular pathology prevents sensory hair cell loss in Norrie disease.
    Proc Natl Acad Sci U S A. 2024;121:e2322124121.
    PubMed     Abstract available


    November 2024
  17. WANG Y, Thakur D, Duge E, Murphy C, et al
    Deafness due to loss of a TRPV channel eliminates mating behavior in Aedes aegypti males.
    Proc Natl Acad Sci U S A. 2024;121:e2404324121.
    PubMed     Abstract available


    June 2024
  18. MASRI S, Mowery TM, Fair R, Sanes DH, et al
    Developmental hearing loss-induced perceptual deficits are rescued by genetic restoration of cortical inhibition.
    Proc Natl Acad Sci U S A. 2024;121:e2311570121.
    PubMed     Abstract available


    May 2024
  19. GOTO S, Tsutsumi A, Lee Y, Hosojima M, et al
    Cryo-EM structures elucidate the multiligand receptor nature of megalin.
    Proc Natl Acad Sci U S A. 2024;121:e2318859121.
    PubMed     Abstract available


    April 2024
  20. ROMMELSPACHER H, Bera S, Brommer B, Ward R, et al
    A single dose of AC102 restores hearing in a guinea pig model of noise-induced hearing loss to almost prenoise levels.
    Proc Natl Acad Sci U S A. 2024;121:e2314763121.
    PubMed     Abstract available


    March 2024
  21. ZHAO W, Zhang K, Dong WY, Tang HD, et al
    A pharynx-to-brain axis controls pharyngeal inflammation-induced anxiety.
    Proc Natl Acad Sci U S A. 2024;121:e2312136121.
    PubMed     Abstract available


  22. LI N, Liu S, Zhao D, Du H, et al
    Disruption of Cdh23 exon 68 splicing leads to progressive hearing loss in mice by affecting tip-link stability.
    Proc Natl Acad Sci U S A. 2024;121:e2309656121.
    PubMed     Abstract available


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