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  Ovarian Neoplasms

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Articles published in Clin Cancer Res

Retrieve available abstracts of 53 articles:
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    November 2021
  1. WU X, Zhu J, Wang J, Lin ZQ, et al
    Pamiparib Monotherapy for Patients With Germline BRCA1/2-Mutated Ovarian Cancer Previously Treated With at Least Two Lines of Chemotherapy: A Multicenter, Open-Label, Phase II Study.
    Clin Cancer Res. 2021 Nov 29. pii: 1078-0432.CCR-21-1186.
    PubMed     Abstract available


    October 2021
  2. TIAN L, Xu B, Teng KY, Song M, et al
    Targeting Fc receptor-mediated effects and the "don't eat me" signal with an oncolytic virus expressing an anti-CD47 antibody to treat metastatic ovarian cancer.
    Clin Cancer Res. 2021 Oct 13. pii: 1078-0432.CCR-21-1248.
    PubMed     Abstract available


    September 2021
  3. SCHOUTEN PC, Richters LK, Vis DJ, Kommoss S, et al
    Ovarian cancer specific BRCA-like copy number aberration classifiers detect mutations associated with homologous recombination deficiency in the AGO-TR1 trial.
    Clin Cancer Res. 2021 Sep 30. pii: 1078-0432.CCR-21-1673.
    PubMed     Abstract available


  4. CECIL DL, Liao JB, Dang Y, Coveler AL, et al
    Immunization with a plasmid DNA vaccine encoding the N-terminus of Insulin like Growth Factor Binding Protein-2 in advanced ovarian cancer leads to high level Type I immune responses.
    Clin Cancer Res. 2021 Sep 15. pii: 1078-0432.CCR-21-1579.
    PubMed     Abstract available


  5. WESTIN SN, Labrie M, Litton JK, Blucher A, et al
    Phase 1b dose expansion and translational analyses of olaparib in combination with capivasertib in recurrent endometrial, triple negative breast, and ovarian cancer.
    Clin Cancer Res. 2021 Sep 13. pii: 1078-0432.CCR-21-1656.
    PubMed     Abstract available


    August 2021
  6. SZTUPINSZKI Z, Diossy M, Borcsok J, Prosz A, et al
    Comparative Assessment of Diagnostic Homologous Recombination Deficiency associated mutational signatures in ovarian cancer.
    Clin Cancer Res. 2021 Aug 11. pii: 1078-0432.CCR-21-0981.
    PubMed     Abstract available


  7. KAMAT AA, Fletcher M, Gruman LM, Mueller P, et al
    Editor's Note: The Clinical Relevance of Stromal Matrix Metalloproteinase Expression in Ovarian Cancer.
    Clin Cancer Res. 2021;27:4455.
    PubMed    


    July 2021
  8. THAKER PH, Bradley WH, Leath CA, Gunderson Jackson C, et al
    GEN-1 in Combination with Neoadjuvant Chemotherapy for Patients with Advanced Epithelial Ovarian Cancer: A Phase I Dose-Escalation Study.
    Clin Cancer Res. 2021 Jul 29. pii: 1078-0432.CCR-21-0360.
    PubMed     Abstract available


    May 2021
  9. KANDIMALLA R, Wang W, Yu F, Zhou N, et al
    OCaMIR - A noninvasive, diagnostic signature for early stage ovarian cancer: a multi-cohort retrospective and prospective study.
    Clin Cancer Res. 2021 May 25. pii: 1078-0432.CCR-21-0267.
    PubMed     Abstract available


  10. MIAO YR, Thakkar KN, Qian J, Kariolis MS, et al
    Neutralization of PD-L2 is Essential for Overcoming Immune Checkpoint Blockade Resistance in Ovarian Cancer.
    Clin Cancer Res. 2021 May 19. pii: 1078-0432.CCR-20-0482.
    PubMed     Abstract available


  11. LAUMONT CM, Wouters MCA, Smazynski J, Gierc NS, et al
    Single-cell profiles and prognostic impact of tumor-infiltrating lymphocytes co-expressing CD39, CD103, and PD-1 in ovarian cancer.
    Clin Cancer Res. 2021 May 7. pii: 1078-0432.CCR-20-4394.
    PubMed     Abstract available


    March 2021
  12. THIBODEAUX S, Barnett B, Pandeswara S, Wall S, et al
    Interferon-alpha augments clinical efficacy of regulatory T cell depletion with denileukin diftitox in ovarian cancer.
    Clin Cancer Res. 2021 Mar 26. pii: 1078-0432.CCR-20-4594.
    PubMed     Abstract available


  13. KAZMI F, Nicum S, Roux RL, Spiers L, et al
    A Phase IB open-label, dose-escalation study of NUC1031 in combination with carboplatin for recurrent ovarian cancer.
    Clin Cancer Res. 2021 Mar 19. pii: 1078-0432.CCR-20-4403.
    PubMed     Abstract available


    February 2021
  14. LI N, Bu H, Liu J, Zhu J, et al
    An open-label, multi-center, single-arm, phase 2 study of fluzoparib in patients with germline BRCA1/2 mutation and platinum-sensitive recurrent ovarian cancer.
    Clin Cancer Res. 2021 Feb 8. pii: 1078-0432.CCR-20-3546.
    PubMed     Abstract available


    December 2020
  15. PARACCHINI L, Beltrame L, Grassi T, Inglesi A, et al
    Genome-wide copy number alterations in circulating tumor DNA as a novel biomarker in high grade serous ovarian cancer patients.
    Clin Cancer Res. 2020 Dec 15. pii: 1078-0432.CCR-20-3345.
    PubMed     Abstract available


    September 2020
  16. ISHAK CA, De Carvalho DD
    DNA methylation profiling of premalignant lesions as a path to ovarian cancer early detection.
    Clin Cancer Res. 2020 Sep 28. pii: 1078-0432.CCR-20-3331.
    PubMed     Abstract available


  17. YANG H, Mao W, Rodriguez-Aguayo C, Mangala LS, et al
    Correction: Paclitaxel Sensitivity of Ovarian Cancer Can be Enhanced by Knocking Down Pairs of Kinases that Regulate MAP4 Phosphorylation and Microtubule Stability.
    Clin Cancer Res. 2020;26:5050.
    PubMed    


  18. JIN ZH, Tsuji AB, Degardin M, Sugyo A, et al
    Radiotheranostic Agent (64)Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer.
    Clin Cancer Res. 2020 Sep 15. pii: 1078-0432.CCR-20-1205.
    PubMed     Abstract available


  19. JORDAN K, Sikora MJ, Slansky JE, Minic A, et al
    The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval.
    Clin Cancer Res. 2020 Sep 14. pii: 1078-0432.CCR-20-1762.
    PubMed     Abstract available


    August 2020
  20. MCMULLEN M, Karakasis K, Oza AM
    Moving Beyond BRCA - Incorporating Molecular Assays into Ovarian Cancer trials.
    Clin Cancer Res. 2020 Aug 14. pii: 1078-0432.CCR-20-2429.
    PubMed     Abstract available


    July 2020
  21. MORONEY JW, Powderly J, Lieu CH, Bendell JC, et al
    Safety and Clinical Activity of Atezolizumab Plus Bevacizumab in Patients with Ovarian Cancer: A Phase Ib Study.
    Clin Cancer Res. 2020 Jul 28. pii: 1078-0432.CCR-20-0477.
    PubMed     Abstract available


  22. OZA AM, Estevez-Diz MDP, Grischke EM, Hall M, et al
    A biomarker-enriched, randomized Phase II trial of adavosertib (AZD1775) plus paclitaxel and carboplatin for women with platinum-sensitive TP53-mutant ovarian cancer.
    Clin Cancer Res. 2020 Jul 1. pii: 1078-0432.CCR-20-0219.
    PubMed     Abstract available


    June 2020
  23. MAY T, Oza AM
    Measurement Tool of Chemotherapy Sensitivity in Advanced Ovarian Cancer.
    Clin Cancer Res. 2020 Jun 29. pii: 1078-0432.CCR-20-1376.
    PubMed     Abstract available


    May 2020
  24. LHEUREUX S, Oaknin A, Garg S, Bruce JP, et al
    EVOLVE: A Multicenter Open-Label Single-Arm Clinical and Translational Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer after PARP Inhibition Progression.
    Clin Cancer Res. 2020 May 22. pii: 1078-0432.CCR-19-4121.
    PubMed     Abstract available


  25. JI JX, Cochrane DR, Tessier-Cloutier B, Chen SY, et al
    Arginine depletion therapy with ADI-PEG20 limits tumor growth in argininosuccinate synthase deficient ovarian cancer, including small cell carcinoma of the ovary, hypercalcemic type.
    Clin Cancer Res. 2020 May 14. pii: 1078-0432.CCR-19-1905.
    PubMed     Abstract available


  26. LAMPERT EJ, Zimmer AS, Padget MR, Cimino-Mathews A, et al
    Combination of PARP inhibitor olaparib, and PD-L1 inhibitor durvalumab, in recurrent ovarian cancer: a proof-of-concept phase 2 study.
    Clin Cancer Res. 2020 May 12. pii: 1078-0432.CCR-20-0056.
    PubMed     Abstract available


    April 2020
  27. LI J, Pan C, Boese AC, Kang J, et al
    DGKA provides platinum resistance in ovarian cancer through activation of cJUN-WEE1 signaling.
    Clin Cancer Res. 2020 Apr 27. pii: 1078-0432.CCR-19-3790.
    PubMed     Abstract available


    March 2020
  28. YOU B, Robelin P, Tod M, Louvet C, et al
    CA-125 ELIMination rate constant K (KELIM) Is A Marker Of Chemosensitivity In Patients With Ovarian Cancer: Results from the Phase II CHIVA trial.
    Clin Cancer Res. 2020 Mar 24. pii: 1078-0432.CCR-20-0054.
    PubMed     Abstract available


    February 2020
  29. HARRIS RS, Serebrenik AA, Argyris P, Jarvis MC, et al
    The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer.
    Clin Cancer Res. 2020 Feb 14. pii: 1078-0432.CCR-19-2786.
    PubMed     Abstract available


    January 2020
  30. ALVAREZ SECORD A, Bell Burdett K, Owzar K, Tritchler D, et al
    Predictive blood-based biomarkers in epithelial ovarian cancer patients treated with carboplatin and paclitaxel with or without bevacizumab: Results from GOG-0218.
    Clin Cancer Res. 2020 Jan 9. pii: 1078-0432.CCR-19-0226.
    PubMed     Abstract available


    December 2019
  31. LI F, Zhang Z, Cai J, Chen X, et al
    Primary preclinical and clinical Evaluation of 68Ga-DOTA-TMVP1 as a novel VEGFR-3 PET Imaging Radiotracer in Gynecological Cancer.
    Clin Cancer Res. 2019 Dec 16. pii: 1078-0432.CCR-19-1845.
    PubMed     Abstract available


  32. OZA AM, Matulonis UA, Alvarez Secord A, Nemunaitis J, et al
    A randomized phase 2 trial of epigenetic priming with guadecitabine and carboplatin in platinum-resistant, recurrent ovarian cancer.
    Clin Cancer Res. 2019 Dec 12. pii: 1078-0432.CCR-19-1638.
    PubMed     Abstract available


    October 2019
  33. HANDLEY KF, Sood AK
    A solution to the dilution: The role for biomarkers in advanced ovarian cancer.
    Clin Cancer Res. 2019 Oct 31. pii: 1078-0432.CCR-19-3072.
    PubMed     Abstract available


  34. SOLIMAN PT, Westin SN, Iglesias DA, Fellman BM, et al
    Everolimus, letrozole, and metformin in women with advanced or recurrent endometrioid endometrial cancer: A multi-center, single arm, phase II study.
    Clin Cancer Res. 2019 Oct 18. pii: 1078-0432.CCR-19-0471.
    PubMed     Abstract available


  35. MCCLOSKEY CW, Cook DP, Kelly BS, Azzi F, et al
    Metformin abrogates age-associated ovarian fibrosis.
    Clin Cancer Res. 2019 Oct 9. pii: 1078-0432.CCR-19-0603.
    PubMed     Abstract available


    September 2019
  36. SHEE K, Wells JD, Ung M, Hampsch RA, et al
    A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition.
    Clin Cancer Res. 2019 Sep 26. pii: 1078-0432.CCR-18-2213.
    PubMed     Abstract available


  37. GERBER DE, Infante JR, Gordon MS, Goldberg SB, et al
    Phase Ia Study of Anti-NaPi2b Antibody-Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer Patients.
    Clin Cancer Res. 2019 Sep 20. pii: 1078-0432.CCR-18-3965.
    PubMed     Abstract available


  38. BONILLA L, Oza AM
    Targeting TGFbeta Pathway in Adult Granulosa Cell Tumor: Opening Pandora's Box?
    Clin Cancer Res. 2019;25:5432-5434.
    PubMed     Abstract available


  39. MAITLAND ML, O'Cearbhaill RE, Gobburu J
    Cancer Clinical Investigators Should Converge with Pharmacometricians.
    Clin Cancer Res. 2019;25:5182-5184.
    PubMed     Abstract available


    August 2019
  40. YANG H, Shu Z, Jiang Y, Mao W, et al
    6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers.
    Clin Cancer Res. 2019 Aug 7. pii: 1078-0432.CCR-18-3448.
    PubMed     Abstract available


    July 2019
  41. YEUNG TL, Leung CS, Yip KP, Sheng J, et al
    Anticancer immunotherapy by MFAP5 blockade inhibits fibrosis and enhances chemosensitivity in ovarian and pancreatic cancer.
    Clin Cancer Res. 2019 Jul 22. pii: 1078-0432.CCR-19-0187.
    PubMed     Abstract available


  42. TINKER AV, Hirte HW, Provencher DM, Butler MO, et al
    Dose-ranging and cohort-expansion study of monalizumab(IPH2201) in advanced gynecologic malignancies:A trial of the Canadian Cancer Trials Group (CCTG):IND221.
    Clin Cancer Res. 2019 Jul 15. pii: 1078-0432.CCR-19-0298.
    PubMed     Abstract available


    April 2019
  43. POSTOVIT LM, Dieters-Castator DZ, Rambau PF, Kelemen LE, et al
    Proteomics derived biomarker panel improves diagnostic precision to classify endometrioid and high-grade serous ovarian carcinoma.
    Clin Cancer Res. 2019 Apr 12. pii: 1078-0432.CCR-18-3818.
    PubMed     Abstract available


  44. TAKENAKA M, Kobel M, Garsed DW, Fereday S, et al
    Survival Following Chemotherapy in Ovarian Clear Cell Carcinoma is Not Associated with Pathological Misclassification of Tumor Histotype.
    Clin Cancer Res. 2019 Apr 9. pii: 1078-0432.CCR-18-3691.
    PubMed     Abstract available


    March 2019
  45. BYKOV Y, Zamarin D
    Virus, Vessel, Victory: A Novel Approach to Tumor Killing.
    Clin Cancer Res. 2019;25:1446-1448.
    PubMed     Abstract available


    August 2018
  46. PISANIC TR, Cope L, Lin SF, Yen TT, et al
    Methylomic analysis of ovarian cancers identifies tumor-specific alterations readily detectable in early precursor lesions.
    Clin Cancer Res. 2018 Aug 14. pii: 1078-0432.CCR-18-1199.
    PubMed     Abstract available


  47. LHEUREUX S, Tinker AV, Clarke BA, Ghatage P, et al
    A clinical and molecular Phase II trial of oral ENMD-2076 in ovarian clear cell carcinoma (OCCC): A study of the Princess Margaret Phase II Consortium.
    Clin Cancer Res. 2018 Aug 14. pii: 1078-0432.CCR-18-1244.
    PubMed     Abstract available


    July 2018
  48. CHEN GM, Kannan L, Geistlinger L, Kofia V, et al
    Consensus on Molecular Subtypes of High-grade Serous Ovarian Carcinoma.
    Clin Cancer Res. 2018 Jul 3. pii: 1078-0432.CCR-18-0784.
    PubMed     Abstract available


    May 2018
  49. DENIGER DC, Pasetto A, Robbins PF, Gartner JJ, et al
    T-cell responses to TP53 "hotspot" mutations and unique neoantigens expressed by human ovarian cancers.
    Clin Cancer Res. 2018 May 31. pii: 1078-0432.CCR-18-0573.
    PubMed     Abstract available


    April 2018
  50. CAUMANNS JJ, Berns K, Wisman GBA, Fehrmann RSN, et al
    Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.
    Clin Cancer Res. 2018 Apr 23. pii: 1078-0432.CCR-17-3060.
    PubMed     Abstract available


  51. PULLIAM N, Fang F, Ozes AR, Tang J, et al
    An Effective Epigenetic-PARP inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA-mutations.
    Clin Cancer Res. 2018 Apr 3. pii: 1078-0432.CCR-18-0204.
    PubMed     Abstract available


    February 2018
  52. LANG JD, Hendricks WPD, Orlando KA, Yin H, et al
    Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multi-kinase inhibition.
    Clin Cancer Res. 2018 Feb 9. pii: 1078-0432.CCR-17-1928.
    PubMed     Abstract available


    November 2017
  53. NORQUIST BM, Brady MF, Harrell MI, Walsh T, et al
    Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: an NRG Oncology/Gynecologic Oncology Group Study.
    Clin Cancer Res. 2017 Nov 30. pii: 1078-0432.CCR-17-1327.
    PubMed     Abstract available


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