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Pain Management

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 25 articles: HTML format

Single Articles

December 2025
1. CHEN D, Wang J, Song XJ, Ding ZJ, et al
   Galectin-related protein, a key contributor, drives diabetes-associated neuropathic pain.
   Proc Natl Acad Sci U S A. 2025;122:e2527641122.
   PubMed     Abstract available
   
   
   
2. GOUDARZI MH, Robinson SD, Cardoso FC, Suryamohan K, et al
   Genome of venomous caterpillar Doratifera vulnerans reveals recruitment of immune peptides and their adaptation as pain-inducing toxins.
   Proc Natl Acad Sci U S A. 2025;122:e2513640122.
   PubMed     Abstract available
   
   
   November 2025
3. LU X, Chen G, Hong W, Hu S, et al
   Alleviation of negative emotional and pain responses through amygdala-hypothalamic social circuit activation.
   Proc Natl Acad Sci U S A. 2025;122:e2511106122.
   PubMed     Abstract available
   
   
   
4. HABIB AM, Li S, Zhang C, Ji M, et al
   MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain.
   Proc Natl Acad Sci U S A. 2025;122:e2512426122.
   PubMed     Abstract available
   
   
   
5. HESTEHAVE S, Florea R, Singleton S, Fedorec AJH, et al
   Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms.
   Proc Natl Acad Sci U S A. 2025;122:e2517405122.
   PubMed     Abstract available
   
   
   September 2025
6. ZHANG X, Liu Q, Liu C, Wang Z, et al
   Oxytocin and vasopressin enhance social pain empathy via common and distinct of neural expressions, genetic pathways, and networks.
   Proc Natl Acad Sci U S A. 2025;122:e2520651122.
   PubMed     Abstract available
   
   
   August 2025
7. WANG C, Ji H, Wang H, Chen Z, et al
   Unraveling the neuroimmune mechanisms in cancer-induced bone pain: New horizons for therapeutic intervention of the two-phase paradigm.
   Proc Natl Acad Sci U S A. 2025;122:e2503779122.
   PubMed     Abstract available
   
   
   July 2025
8. KANG SJ, Liu S, Kim JH, Kim DI, et al
   Thalamic CGRP neurons define a spinothalamic pathway for affective pain.
   Proc Natl Acad Sci U S A. 2025;122:e2505889122.
   PubMed     Abstract available
   
   
   
9. LANCON K, Tian J, Bach H, Drapeau P, et al
   Synergistic deficits in parvalbumin interneurons and dopamine signaling drive ACC dysfunction in chronic pain.
   Proc Natl Acad Sci U S A. 2025;122:e2502558122.
   PubMed     Abstract available
   
   
   
10. WAXMAN SG, Vasylyev DV
    Inhibiting Nav1.8 for pain: Lessons from patients and from neurons.
    Proc Natl Acad Sci U S A. 2025;122:e2511228122.
    PubMed    
    
    
    May 2025
11. STRATTON HJ, Dolatyari M, Kopruszinski C, Ghetti A, et al
    A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain.
    Proc Natl Acad Sci U S A. 2025;122:e2501229122.
    PubMed     Abstract available
    
    
    March 2025
12. TOBORI S, Tamada K, Uemura N, Sawada K, et al
    Spinal TRPC3 promotes neuropathic pain and coordinates phospholipase C-induced mechanical hypersensitivity.
    Proc Natl Acad Sci U S A. 2025;122:e2416828122.
    PubMed     Abstract available
    
    
    
13. OGGERO S, Voisin MB, Picco F, Huerta MA, et al
    Activation of proresolving macrophages in dorsal root ganglia attenuates persistent arthritis pain.
    Proc Natl Acad Sci U S A. 2025;122:e2416343122.
    PubMed     Abstract available
    
    
    January 2025
14. WIRT JL, Assis Ferreira L, Jesus CHA, Woodward TJ, et al
    Efficacy of GABA aminotransferase inactivator OV329 in models of neuropathic and inflammatory pain without tolerance or addiction.
    Proc Natl Acad Sci U S A. 2025;122:e2318833121.
    PubMed     Abstract available
    
    
    December 2024
15. PATTISON LA, Rickman RH, Hilton H, Dannawi M, et al
    Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory joint pain.
    Proc Natl Acad Sci U S A. 2024;121:e2410653121.
    PubMed     Abstract available
    
    
    November 2024
16. CHEN T, Liu WB, Zhu SJ, Aji A, et al
    Differential modulation of pain and associated anxiety by GABAergic neuronal circuits in the lateral habenula.
    Proc Natl Acad Sci U S A. 2024;121:e2409443121.
    PubMed     Abstract available
    
    
    October 2024
17. CHANG D, Caterina MJ
    Pinning down a perpetrator in postsurgical eye pain.
    Proc Natl Acad Sci U S A. 2024;121:e2417221121.
    PubMed    
    
    
    August 2024
18. GARZA-CARBAJAL A, Bavencoffe A, Herrera JJ, Johnson KN, et al
    Mechanism of gabapentinoid potentiation of opioid effects on cyclic AMP signaling in neuropathic pain.
    Proc Natl Acad Sci U S A. 2024;121:e2405465121.
    PubMed     Abstract available
    
    
    
19. GUZIKEVITS M, Gordon-Hecker T, Rekhtman D, Salameh S, et al
    Sex bias in pain management decisions.
    Proc Natl Acad Sci U S A. 2024;121:e2401331121.
    PubMed     Abstract available
    
    
    July 2024
20. QIU H, Miraucourt LS, Petitjean H, Xu M, et al
    Parvalbumin gates chronic pain through the modulation of firing patterns in inhibitory neurons.
    Proc Natl Acad Sci U S A. 2024;121:e2403777121.
    PubMed     Abstract available
    
    
    June 2024
21. LEE SA, Lee JJ, Han J, Choi M, et al
    Brain representations of affective valence and intensity in sustained pleasure and pain.
    Proc Natl Acad Sci U S A. 2024;121:e2310433121.
    PubMed     Abstract available
    
    
    February 2024
22. HUANG Z, Zhang Y, Wang S, Qi R, et al
    FOXD3-mediated transactivation of ALKBH5 promotes neuropathic pain via m(6)A-dependent stabilization of 5-HT3A mRNA in sensory neurons.
    Proc Natl Acad Sci U S A. 2024;121:e2312861121.
    PubMed     Abstract available
    
    
    December 2023
23. YOUSUF MS, Sahn JJ, Yang H, David ET, et al
    Highly specific sigma(2)R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response.
    Proc Natl Acad Sci U S A. 2023;120:e2306090120.
    PubMed     Abstract available
    
    
    
24. CHEN M, Shin M, Ware TB, Donvito G, et al
    Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling.
    Proc Natl Acad Sci U S A. 2023;120:e2304900120.
    PubMed     Abstract available
    
    
    November 2023
25. GOMEZ K, Santiago U, Nelson TS, Allen HN, et al
    A peptidomimetic modulator of the Ca(V)2.2 N-type calcium channel for chronic pain.
    Proc Natl Acad Sci U S A. 2023;120:e2305215120.
    PubMed     Abstract available
    
    

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