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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 33 articles:
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Single Articles


    September 2026
  1. CORMIE MA, Mouseli P, Martini C, De Silva K, et al
    Nociceptive sensitization and pain perception are dissociable in humans.
    Proc Natl Acad Sci U S A. 2026;123:e2603667123.
    PubMed     Abstract available


    August 2026
  2. MADASU C, Sirupangi T, Herrera GJ, Bohren KM, et al
    Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.
    Proc Natl Acad Sci U S A. 2026;123:e2607561123.
    PubMed     Abstract available



  3. Correction for Qiu et al., Parvalbumin gates chronic pain through the modulation of firing patterns in inhibitory neurons.
    Proc Natl Acad Sci U S A. 2026;123:e2626378123.
    PubMed    


    July 2026
  4. SUETO D, Uchiyama S, Ono T, Watanabe M, et al
    A population of primary afferent sensory neurons mediates pain relief through nocifensive coping behavior in mice.
    Proc Natl Acad Sci U S A. 2026;123:e2601766123.
    PubMed     Abstract available


    February 2026
  5. YAZDANPANAH A, Jung H, Soltani A, Wager TD, et al
    Social information creates self-fulfilling prophecies in judgments of pain, vicarious pain, and cognitive effort.
    Proc Natl Acad Sci U S A. 2026;123:e2513856123.
    PubMed     Abstract available


  6. WU S
    A neuron-astrocyte signaling axis in the ACC sustains diabetic neuropathic pain.
    Proc Natl Acad Sci U S A. 2026;123:e2533902123.
    PubMed    


    January 2026
  7. PANDEY VK, Acharya TK, Willcox KF, Dembla S, et al
    Peripheral nerve injury reduces macrophage efferocytosis to facilitate neuropathic pain.
    Proc Natl Acad Sci U S A. 2026;123:e2511401122.
    PubMed     Abstract available


    December 2025
  8. GAO Y, Zhang J, Zhang H, Chow L, et al
    A neuromorphic robotic electronic skin with active pain and injury perception.
    Proc Natl Acad Sci U S A. 2025;122:e2520922122.
    PubMed     Abstract available


  9. CHEN D, Wang J, Song XJ, Ding ZJ, et al
    Galectin-related protein, a key contributor, drives diabetes-associated neuropathic pain.
    Proc Natl Acad Sci U S A. 2025;122:e2527641122.
    PubMed     Abstract available


  10. GOUDARZI MH, Robinson SD, Cardoso FC, Suryamohan K, et al
    Genome of venomous caterpillar Doratifera vulnerans reveals recruitment of immune peptides and their adaptation as pain-inducing toxins.
    Proc Natl Acad Sci U S A. 2025;122:e2513640122.
    PubMed     Abstract available


    November 2025
  11. LU X, Chen G, Hong W, Hu S, et al
    Alleviation of negative emotional and pain responses through amygdala-hypothalamic social circuit activation.
    Proc Natl Acad Sci U S A. 2025;122:e2511106122.
    PubMed     Abstract available


  12. HABIB AM, Li S, Zhang C, Ji M, et al
    MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain.
    Proc Natl Acad Sci U S A. 2025;122:e2512426122.
    PubMed     Abstract available


  13. HESTEHAVE S, Florea R, Singleton S, Fedorec AJH, et al
    Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms.
    Proc Natl Acad Sci U S A. 2025;122:e2517405122.
    PubMed     Abstract available


    September 2025
  14. ZHANG X, Liu Q, Liu C, Wang Z, et al
    Oxytocin and vasopressin enhance social pain empathy via common and distinct of neural expressions, genetic pathways, and networks.
    Proc Natl Acad Sci U S A. 2025;122:e2520651122.
    PubMed     Abstract available


    August 2025
  15. WANG C, Ji H, Wang H, Chen Z, et al
    Unraveling the neuroimmune mechanisms in cancer-induced bone pain: New horizons for therapeutic intervention of the two-phase paradigm.
    Proc Natl Acad Sci U S A. 2025;122:e2503779122.
    PubMed     Abstract available


    July 2025
  16. KANG SJ, Liu S, Kim JH, Kim DI, et al
    Thalamic CGRP neurons define a spinothalamic pathway for affective pain.
    Proc Natl Acad Sci U S A. 2025;122:e2505889122.
    PubMed     Abstract available


  17. LANCON K, Tian J, Bach H, Drapeau P, et al
    Synergistic deficits in parvalbumin interneurons and dopamine signaling drive ACC dysfunction in chronic pain.
    Proc Natl Acad Sci U S A. 2025;122:e2502558122.
    PubMed     Abstract available


  18. WAXMAN SG, Vasylyev DV
    Inhibiting Nav1.8 for pain: Lessons from patients and from neurons.
    Proc Natl Acad Sci U S A. 2025;122:e2511228122.
    PubMed    


    May 2025
  19. STRATTON HJ, Dolatyari M, Kopruszinski C, Ghetti A, et al
    A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain.
    Proc Natl Acad Sci U S A. 2025;122:e2501229122.
    PubMed     Abstract available


    March 2025
  20. TOBORI S, Tamada K, Uemura N, Sawada K, et al
    Spinal TRPC3 promotes neuropathic pain and coordinates phospholipase C-induced mechanical hypersensitivity.
    Proc Natl Acad Sci U S A. 2025;122:e2416828122.
    PubMed     Abstract available


  21. OGGERO S, Voisin MB, Picco F, Huerta MA, et al
    Activation of proresolving macrophages in dorsal root ganglia attenuates persistent arthritis pain.
    Proc Natl Acad Sci U S A. 2025;122:e2416343122.
    PubMed     Abstract available


    January 2025
  22. WIRT JL, Assis Ferreira L, Jesus CHA, Woodward TJ, et al
    Efficacy of GABA aminotransferase inactivator OV329 in models of neuropathic and inflammatory pain without tolerance or addiction.
    Proc Natl Acad Sci U S A. 2025;122:e2318833121.
    PubMed     Abstract available


    December 2024
  23. PATTISON LA, Rickman RH, Hilton H, Dannawi M, et al
    Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory joint pain.
    Proc Natl Acad Sci U S A. 2024;121:e2410653121.
    PubMed     Abstract available


    November 2024
  24. CHEN T, Liu WB, Zhu SJ, Aji A, et al
    Differential modulation of pain and associated anxiety by GABAergic neuronal circuits in the lateral habenula.
    Proc Natl Acad Sci U S A. 2024;121:e2409443121.
    PubMed     Abstract available


    October 2024
  25. CHANG D, Caterina MJ
    Pinning down a perpetrator in postsurgical eye pain.
    Proc Natl Acad Sci U S A. 2024;121:e2417221121.
    PubMed    


    August 2024
  26. GARZA-CARBAJAL A, Bavencoffe A, Herrera JJ, Johnson KN, et al
    Mechanism of gabapentinoid potentiation of opioid effects on cyclic AMP signaling in neuropathic pain.
    Proc Natl Acad Sci U S A. 2024;121:e2405465121.
    PubMed     Abstract available


  27. GUZIKEVITS M, Gordon-Hecker T, Rekhtman D, Salameh S, et al
    Sex bias in pain management decisions.
    Proc Natl Acad Sci U S A. 2024;121:e2401331121.
    PubMed     Abstract available


    July 2024
  28. QIU H, Miraucourt LS, Petitjean H, Xu M, et al
    Parvalbumin gates chronic pain through the modulation of firing patterns in inhibitory neurons.
    Proc Natl Acad Sci U S A. 2024;121:e2403777121.
    PubMed     Abstract available


    June 2024
  29. LEE SA, Lee JJ, Han J, Choi M, et al
    Brain representations of affective valence and intensity in sustained pleasure and pain.
    Proc Natl Acad Sci U S A. 2024;121:e2310433121.
    PubMed     Abstract available


    February 2024
  30. HUANG Z, Zhang Y, Wang S, Qi R, et al
    FOXD3-mediated transactivation of ALKBH5 promotes neuropathic pain via m(6)A-dependent stabilization of 5-HT3A mRNA in sensory neurons.
    Proc Natl Acad Sci U S A. 2024;121:e2312861121.
    PubMed     Abstract available


    December 2023
  31. YOUSUF MS, Sahn JJ, Yang H, David ET, et al
    Highly specific sigma(2)R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response.
    Proc Natl Acad Sci U S A. 2023;120:e2306090120.
    PubMed     Abstract available


  32. CHEN M, Shin M, Ware TB, Donvito G, et al
    Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling.
    Proc Natl Acad Sci U S A. 2023;120:e2304900120.
    PubMed     Abstract available


    November 2023
  33. GOMEZ K, Santiago U, Nelson TS, Allen HN, et al
    A peptidomimetic modulator of the Ca(V)2.2 N-type calcium channel for chronic pain.
    Proc Natl Acad Sci U S A. 2023;120:e2305215120.
    PubMed     Abstract available


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