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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 26 articles:
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Single Articles


    November 2022
  1. RUBIN DE CELIS MF, Garcia-Martin R, Syed I, Lee J, et al
    PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53.
    Proc Natl Acad Sci U S A. 2022;119:e2206923119.
    PubMed     Abstract available


    October 2022
  2. MICALIZZI DS, Che D, Nicholson BT, Edd JF, et al
    Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody.
    Proc Natl Acad Sci U S A. 2022;119:e2209563119.
    PubMed     Abstract available


  3. SAAD MI, Weng T, Lundy J, Gearing LJ, et al
    Blockade of the protease ADAM17 ameliorates experimental pancreatitis.
    Proc Natl Acad Sci U S A. 2022;119:e2213744119.
    PubMed     Abstract available


    August 2022
  4. GUO A, Zhang J, He B, Li A, et al
    Quantitative, in situ visualization of intracellular insulin vesicles in pancreatic beta cells.
    Proc Natl Acad Sci U S A. 2022;119:e2202695119.
    PubMed     Abstract available


    May 2022

  5. Correction for Lebedeva et al., Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.
    Proc Natl Acad Sci U S A. 2022;119:e2204209119.
    PubMed    


  6. PRINCIPE DR, Aissa AF, Kumar S, Pham TND, et al
    Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2200143119.
    PubMed     Abstract available


  7. NAPOLEON JV, Sagar S, Kubica SP, Boghean L, et al
    Small-molecule IKKbeta activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
    Proc Natl Acad Sci U S A. 2022;119:e2115071119.
    PubMed     Abstract available


    April 2022

  8. Correction for Morton et al., Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2204610119.
    PubMed    


  9. LARUE MM, Parker S, Puccini J, Cammer M, et al
    Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2119168119.
    PubMed     Abstract available


    March 2022
  10. DOFFO J, Bamopoulos SA, Kose H, Orben F, et al
    NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  11. PRINCIPE DR, Xiong R, Li Y, Pham TND, et al
    XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  12. KATTAN WE, Liu J, Montufar-Solis D, Liang H, et al
    Components of the phosphatidylserine endoplasmic reticulum to plasma membrane transport mechanism as targets for KRAS inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  13. LIN CW, Wang YJ, Lai TY, Hsu TL, et al
    Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  14. WOLFE AL, Zhou Q, Toska E, Galeas J, et al
    UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  15. KING ME, Zhang J, Lin JQ, Garza KY, et al
    Rapid diagnosis and tumor margin assessment during pancreatic cancer surgery with the MasSpec Pen technology.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  16. YANG Y, Wang H, He J, Shi W, et al
    A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  17. CHENG DK, Oni TE, Thalappillil JS, Park Y, et al
    Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  18. TSAI PY, Lee MS, Jadhav U, Naqvi I, et al
    Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  19. MOORE AM, Zhou L, Cui J, Li L, et al
    NAD(+) depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  20. MUKHOPADHYAY S, Biancur DE, Parker SJ, Yamamoto K, et al
    Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  21. Correction to Supporting Information for Qadir et al., Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  22. MUCCIOLO G, Curcio C, Roux C, Li WY, et al
    IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2020
  23. GRBOVIC-HUEZO O, Pitter KL, Lecomte N, Saglimbeni J, et al
    Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma.
    Proc Natl Acad Sci U S A. 2020 Nov 16. pii: 1920240117.
    PubMed     Abstract available


    October 2020
  24. BIASCI D, Smoragiewicz M, Connell CM, Wang Z, et al
    CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response.
    Proc Natl Acad Sci U S A. 2020 Oct 30. pii: 2013644117.
    PubMed     Abstract available


  25. WANG B, Lin H, Li X, Lu W, et al
    The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic beta-cells.
    Proc Natl Acad Sci U S A. 2020 Oct 29. pii: 2016997117.
    PubMed     Abstract available


  26. WEI X, Yang J, Adair SJ, Ozturk H, et al
    Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells.
    Proc Natl Acad Sci U S A. 2020 Oct 23. pii: 2009899117.
    PubMed     Abstract available


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