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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 33 articles:
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Single Articles


    May 2022

  1. Correction for Lebedeva et al., Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.
    Proc Natl Acad Sci U S A. 2022;119:e2204209119.
    PubMed    


  2. PRINCIPE DR, Aissa AF, Kumar S, Pham TND, et al
    Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2200143119.
    PubMed     Abstract available


  3. NAPOLEON JV, Sagar S, Kubica SP, Boghean L, et al
    Small-molecule IKKbeta activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
    Proc Natl Acad Sci U S A. 2022;119:e2115071119.
    PubMed     Abstract available


    April 2022

  4. Correction for Morton et al., Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2204610119.
    PubMed    


  5. LARUE MM, Parker S, Puccini J, Cammer M, et al
    Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2119168119.
    PubMed     Abstract available


    March 2022
  6. DOFFO J, Bamopoulos SA, Kose H, Orben F, et al
    NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  7. PRINCIPE DR, Xiong R, Li Y, Pham TND, et al
    XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  8. KATTAN WE, Liu J, Montufar-Solis D, Liang H, et al
    Components of the phosphatidylserine endoplasmic reticulum to plasma membrane transport mechanism as targets for KRAS inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  9. LIN CW, Wang YJ, Lai TY, Hsu TL, et al
    Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  10. WOLFE AL, Zhou Q, Toska E, Galeas J, et al
    UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  11. KING ME, Zhang J, Lin JQ, Garza KY, et al
    Rapid diagnosis and tumor margin assessment during pancreatic cancer surgery with the MasSpec Pen technology.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  12. YANG Y, Wang H, He J, Shi W, et al
    A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  13. CHENG DK, Oni TE, Thalappillil JS, Park Y, et al
    Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  14. TSAI PY, Lee MS, Jadhav U, Naqvi I, et al
    Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  15. MOORE AM, Zhou L, Cui J, Li L, et al
    NAD(+) depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  16. MUKHOPADHYAY S, Biancur DE, Parker SJ, Yamamoto K, et al
    Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  17. Correction to Supporting Information for Qadir et al., Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  18. MUCCIOLO G, Curcio C, Roux C, Li WY, et al
    IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2020
  19. GRBOVIC-HUEZO O, Pitter KL, Lecomte N, Saglimbeni J, et al
    Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma.
    Proc Natl Acad Sci U S A. 2020 Nov 16. pii: 1920240117.
    PubMed     Abstract available


    October 2020
  20. BIASCI D, Smoragiewicz M, Connell CM, Wang Z, et al
    CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response.
    Proc Natl Acad Sci U S A. 2020 Oct 30. pii: 2013644117.
    PubMed     Abstract available


  21. WANG B, Lin H, Li X, Lu W, et al
    The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic beta-cells.
    Proc Natl Acad Sci U S A. 2020 Oct 29. pii: 2016997117.
    PubMed     Abstract available


  22. WEI X, Yang J, Adair SJ, Ozturk H, et al
    Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells.
    Proc Natl Acad Sci U S A. 2020 Oct 23. pii: 2009899117.
    PubMed     Abstract available


    May 2020
  23. GUPTA R, Malvi P, Parajuli KR, Janostiak R, et al
    KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity.
    Proc Natl Acad Sci U S A. 2020 May 19. pii: 2005156117.
    PubMed     Abstract available


  24. SOMERVILLE TDD, Xu Y, Wu XS, Maia-Silva D, et al
    ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2020 May 8. pii: 1921484117.
    PubMed     Abstract available


    April 2020
  25. QADIR MMF, Alvarez-Cubela S, Klein D, van Dijk J, et al
    Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020 Apr 30. pii: 1918314117.
    PubMed     Abstract available


  26. GONZALEZ-MORO I, Olazagoitia-Garmendia A, Colli ML, Cobo-Vuilleumier N, et al
    The T1D-associated lncRNA Lnc13 modulates human pancreatic beta cell inflammation by allele-specific stabilization of STAT1 mRNA.
    Proc Natl Acad Sci U S A. 2020 Apr 13. pii: 1914353117.
    PubMed     Abstract available


    March 2020
  27. WASYLISHEN AR, Sun C, Chau GP, Qi Y, et al
    Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress.
    Proc Natl Acad Sci U S A. 2020;117:6622-6629.
    PubMed     Abstract available


    January 2020
  28. PETRENKO V, Gandasi NR, Sage D, Tengholm A, et al
    In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis.
    Proc Natl Acad Sci U S A. 2020 Jan 21. pii: 1916539117.
    PubMed     Abstract available



  29. Correction for Porter et al., Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2020 Jan 13. pii: 1922469117.
    PubMed    


    December 2019
  30. PORTER RL, Magnus NKC, Thapar V, Morris R, et al
    Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 1914915116.
    PubMed     Abstract available


  31. DRIEHUIS E, van Hoeck A, Moore K, Kolders S, et al
    Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.
    Proc Natl Acad Sci U S A. 2019 Dec 9. pii: 1911273116.
    PubMed     Abstract available


    October 2019
  32. WEN CL, Huang K, Jiang LL, Lu XX, et al
    An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2019 Oct 29. pii: 1914557116.
    PubMed     Abstract available


    September 2019
  33. MAMEISHVILI E, Serafimidis I, Iwaszkiewicz S, Lesche M, et al
    Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
    Proc Natl Acad Sci U S A. 2019 Sep 23. pii: 1901075116.
    PubMed     Abstract available


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