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Parkinson's Disease

Free Subscription Articles published in J Biol Chem Retrieve available abstracts of 24 articles: HTML format

Single Articles

September 2025
1. ADHIKARI A, Tripathi A, Chiang CY, Sherpa P, et al
   Allosteric regulation of the Golgi-localized PPM1H phosphatase by Rab GTPases modulates LRRK2 substrate dephosphorylation in Parkinson's disease.
   J Biol Chem. 2025 Sep 3:110679. doi: 10.1016/j.jbc.2025.110679.
   PubMed     Abstract available
   
   
   
2. YANG Q, Chen S, Zhang P, Lu Z, et al
   Negatively charged alpha-synuclein condensate modulates partitioning of molecules.
   J Biol Chem. 2025;301:110530.
   PubMed     Abstract available
   
   
   August 2025
3. SAWAI T, Nakamura Y, Arawaka S
   Secretory autophagy mediates lysosomal and autophagic degradation for alpha-synuclein proteostasis.
   J Biol Chem. 2025;301:110474.
   PubMed     Abstract available
   
   
   
4. SHEN L, Zhang J, Wang Z, Liu Y, et al
   Targeted degradation of alpha-synuclein by arginine-based PROTACs.
   J Biol Chem. 2025;301:110449.
   PubMed     Abstract available
   
   
   June 2025
5. LESCHZINER AE
   Structural biology of Parkinson's Disease-associated Leucine-Rich Repeat Kinase 2 (LRRK2).
   J Biol Chem. 2025 Jun 14:110376. doi: 10.1016/j.jbc.2025.110376.
   PubMed     Abstract available
   
   
   
6. TI X, Zuo H, Zhao G, Li Y, et al
   Parkin mediates the mitochondrial dysfunction through mRpL18.
   J Biol Chem. 2025;301:110208.
   PubMed     Abstract available
   
   
   May 2025
7. ANISIMOV S, Takahashi M, Kakihana T, Katsuragi Y, et al
   UPS10 inhibits the degradation of alpha-synuclein, a pathogenic factor associated with Parkinson's disease, by inhibiting chaperone-mediated autophagy.
   J Biol Chem. 2025 May 24:110292. doi: 10.1016/j.jbc.2025.110292.
   PubMed     Abstract available
   
   
   April 2025
8. SUN C, Zhou K, DePaola P 4th, Li C, et al
   Structural basis of a distinct alpha-synuclein strain that promotes tau inclusion in neurons.
   J Biol Chem. 2025;301:108351.
   PubMed     Abstract available
   
   
   February 2025
9. BRASSARD R, Arutyunova E, Takyi E, Espinoza-Fonseca LM, et al
   Transmembrane Parkinson's Disease mutation of PINK1 leads to altered mitochondrial anchoring.
   J Biol Chem. 2025 Feb 3:108253. doi: 10.1016/j.jbc.2025.108253.
   PubMed     Abstract available
   
   
   January 2025
10. CHANDRA G, Rangasamy SB, Roy A, Kordower JH, et al
    Withdrawal: Neutralization of RANTES and eotaxin prevents the loss of dopaminergic neurons in a mouse model of Parkinson disease.
    J Biol Chem. 2025;301:108102.
    PubMed    
    
    
    
11. WAGNER JP, Sauve V, Saran A, Gehring K, et al
    Structural basis for the pathogenicity of parkin catalytic domain mutants.
    J Biol Chem. 2025;301:108051.
    PubMed     Abstract available
    
    
    October 2024
12. QIAO Y, Kou J, Tian Y, Ma W, et al
    Subcellular localization and function analysis of PINK1 mitron in PD progression: Mitron modulates mitochondrial morphology to regulate neuronal death.
    J Biol Chem. 2024;300:107773.
    PubMed     Abstract available
    
    
    
13. BAYATI A, McPherson PS
    Alpha-synuclein, autophagy-lysosomal pathway, and Lewy bodies: Mutations, propagation, aggregation, and the formation of inclusions.
    J Biol Chem. 2024;300:107742.
    PubMed     Abstract available
    
    
    July 2024
14. FILIPPINI F, Galli T
    UNVEILING DEFECTS OF SECRETION MECHANISMS IN PARKINSON'S DISEASE.
    J Biol Chem. 2024 Jul 24:107603. doi: 10.1016/j.jbc.2024.107603.
    PubMed     Abstract available
    
    
    
15. WANG Y, Luo S, Su H, Wang Z, et al
    BL-918 activates PINK1/Parkin signaling pathway to ameliorate the progression of Parkinson's disease.
    J Biol Chem. 2024 Jul 9:107543. doi: 10.1016/j.jbc.2024.107543.
    PubMed     Abstract available
    
    
    June 2024
16. WATANABE A, Koyano F, Imai K, Hizukuri Y, et al
    The origin of esterase activity of Parkinson's disease causative factor DJ-1 implied by evolutionary trace analysis of its prokaryotic homolog HchA.
    J Biol Chem. 2024 Jun 13:107476. doi: 10.1016/j.jbc.2024.107476.
    PubMed     Abstract available
    
    
    
17. DEDERER V, Sanz Murillo M, Karasmanis EP, Hatch KS, et al
    A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2.
    J Biol Chem. 2024 Jun 12:107469. doi: 10.1016/j.jbc.2024.107469.
    PubMed     Abstract available
    
    
    
18. MAJUMDER S, Srivastava M, Alam P, Saha S, et al
    Hotspot site microenvironment in the deubiquitinase OTUB1 drives its stability and aggregation.
    J Biol Chem. 2024;300:107315.
    PubMed     Abstract available
    
    
    March 2024
19. LIU HN, Wang T, Hu JJ, Chen L, et al
    The disordered protein SERF promotes alpha-Synuclein aggregation through liquid-liquid phase separation.
    J Biol Chem. 2024;300:105667.
    PubMed     Abstract available
    
    
    December 2023
20. PRATT MR, Vocadlo DJ
    Understanding and exploiting the roles of O-GlcNAc in neurodegenerative diseases.
    J Biol Chem. 2023;299:105411.
    PubMed     Abstract available
    
    
    
21. ALI A, Zhaliazka K, Dou T, Holman AP, et al
    The toxicities of A30P and A53T alpha-synuclein fibrils can be uniquely altered by the length and saturation of fatty acids in phosphatidylserine.
    J Biol Chem. 2023;299:105383.
    PubMed     Abstract available
    
    
    October 2023
22. UNAPANTA A, Shavarebi F, Porath J, Shen Y, et al
    Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes.
    J Biol Chem. 2023;299:105192.
    PubMed     Abstract available
    
    
    April 2023
23. SUN C, Zhou K, DePaola P 4th, Shin WS, et al
    Cryo-EM structure of amyloid fibril formed by alpha-synuclein hereditary A53E mutation reveals a distinct protofilament interface.
    J Biol Chem. 2023;299:104566.
    PubMed     Abstract available
    
    
    March 2023
24. LEE SH, Lee YJ, Jung S, Chung KC, et al
    E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide.
    J Biol Chem. 2023;299:102909.
    PubMed     Abstract available
    
    

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