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Articles published in J Biol Chem

Retrieve available abstracts of 22 articles:
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Single Articles


    May 2019
  1. FROULA JM, Castellana-Cruz M, Anabtawi NM, Camino JD, et al
    Defining alpha-synuclein species responsible for Parkinson disease phenotypes in mice.
    J Biol Chem. 2019 May 29. pii: RA119.007743. doi: 10.1074/jbc.RA119.007743.
    PubMed     Text format     Abstract available


  2. MCGLINCHEY RP, Lacy SM, Huffer KE, Tayebi N, et al
    C-terminal alpha-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease.
    J Biol Chem. 2019 May 15. pii: RA119.008930. doi: 10.1074/jbc.RA119.008930.
    PubMed     Text format     Abstract available


    April 2019
  3. PONZINI E, De Palma A, Cerboni L, Natalello A, et al
    Methionine oxidation in alpha-synuclein inhibits its propensity for ordered secondary structure.
    J Biol Chem. 2019;294:5657-5665.
    PubMed     Text format     Abstract available


    February 2019
  4. WU CX, Liao J, Park Y, Reed X, et al
    Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.
    J Biol Chem. 2019 Feb 22. pii: RA119.007631. doi: 10.1074/jbc.RA119.007631.
    PubMed     Text format     Abstract available


    November 2018
  5. YAMASAKI TR, Holmes BB, Furman JL, Dhavale DD, et al
    Parkinson's disease and multiple system atrophy have distinct alpha-synuclein seed characteristics.
    J Biol Chem. 2018 Nov 26. pii: RA118.004471. doi: 10.1074/jbc.RA118.004471.
    PubMed     Text format     Abstract available


    September 2018
  6. TERADA M, Suzuki G, Nonaka T, Kametani F, et al
    The effect of truncation on prion-like properties of alpha-synuclein.
    J Biol Chem. 2018;293:13910-13920.
    PubMed     Text format     Abstract available


    April 2018
  7. GIGUERE N, Pacelli C, Saumure C, Bourque MJ, et al
    Comparative analysis of Parkinson's disease-associated genes reveals altered survival and bioenergetics of parkin-deficient dopamine neurons in mice.
    J Biol Chem. 2018 Apr 26. pii: RA117.000499. doi: 10.1074/jbc.RA117.000499.
    PubMed     Text format     Abstract available


    March 2018
  8. AGUIRRE JD, Dunkerley KM, Lam R, Rusal M, et al
    Impact of altered phosphorylation on loss of function of juvenile Parkinsonism-associated genetic variants of the E3 ligase parkin.
    J Biol Chem. 2018 Mar 12. pii: RA117.000605. doi: 10.1074/jbc.RA117.000605.
    PubMed     Text format     Abstract available


    January 2018
  9. FLYNN JD, McGlinchey RP, Walker RL 3rd, Lee JC, et al
    Structural features of alpha-synuclein amyloid fibrils revealed by Raman spectroscopy.
    J Biol Chem. 2018;293:767-776.
    PubMed     Text format     Abstract available


    September 2017
  10. ASJAD HMM, Kasture A, El-Kasaby A, Sackel M, et al
    PHARMACOCHAPERONING IN A DROSOPHILA MODEL SYSTEM RESCUES HUMAN DOPAMINE TRANSPORTER VARIANTS ASSOCIATED WITH INFANTILE/JUVENILE PARKINSONISM.
    J Biol Chem. 2017 Sep 29. pii: jbc.M117.797092. doi: 10.1074/jbc.M117.797092.
    PubMed     Text format     Abstract available


  11. MORIARTY GM, Olson MP, Atieh TB, Janowska MK, et al
    A pH-dependent switch promotes beta-synuclein fibril formation via glutamate residues.
    J Biol Chem. 2017;292:16368-16379.
    PubMed     Text format     Abstract available


  12. LANDAU M
    Getting in charge of beta-synuclein fibrillation.
    J Biol Chem. 2017;292:16380-16381.
    PubMed     Text format     Abstract available


  13. HU ZY, Chen B, Zhang JP, Ma YY, et al
    Upregulation of autophagy-related gene 5 protects dopaminergic neurons in a zebrafish model of Parkinson's disease.
    J Biol Chem. 2017 Sep 19. pii: jbc.M116.764795. doi: 10.1074/jbc.M116.764795.
    PubMed     Text format     Abstract available


    August 2017
  14. AMIREDDY N, Puttapaka SN, Vinnakota RL, Ravuri HG, et al
    The Unintended Mitochondrial Uncoupling Effects of the FDA Approved Anti-Helminth Drug Nitazoxanide Mitigates Experimental Parkinsonism in Mice.
    J Biol Chem. 2017 Aug 10. pii: jbc.M117.791863. doi: 10.1074/jbc.M117.791863.
    PubMed     Text format     Abstract available


    June 2017
  15. DHAVALE DD, Tsai C, Bagchi DP, Engel LA, et al
    A sensitive assay reveals structural requirements for alpha-synuclein fibril growth.
    J Biol Chem. 2017;292:9034-9050.
    PubMed     Text format     Abstract available


    May 2017
  16. YOSHIMURA Y, Holmberg MA, Kukic P, Andersen CB, et al
    MOAG-4 promotes the aggregation of alpha-synuclein by competing with self-protective electrostatic interactions.
    J Biol Chem. 2017;292:8269-8278.
    PubMed     Text format     Abstract available


    April 2017
  17. DE FRANCESCHI G, Fecchio C, Sharon R, Schapira AHV, et al
    alpha-Synuclein structural features inhibit harmful polyunsaturated fatty acid oxidation, suggesting roles in neuroprotection.
    J Biol Chem. 2017;292:6927-6937.
    PubMed     Text format     Abstract available


    November 2016
  18. PFAFF DH, Fleming T, Nawroth P, Teleman AA, et al
    Evidence against a role for the Parkinsonism-associated protein DJ-1 in methylglyoxal detoxification.
    J Biol Chem. 2016 Nov 30. pii: jbc.M116.743823.
    PubMed     Text format     Abstract available


    September 2016
  19. YANG X, Mudgett J, Bou-About G, Champy MF, et al
    Physiological Expression of AMPKgamma2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.
    J Biol Chem. 2016 Sep 12. pii: jbc.M116.738591.
    PubMed     Text format     Abstract available


    July 2016
  20. OIKAWA T, Nonaka T, Terada M, Tamaoka A, et al
    alpha-Synuclein Fibrils Exhibit Gain of Toxic Function, Promoting Tau Aggregation and Inhibiting Microtubule Assembly.
    J Biol Chem. 2016;291:15046-56.
    PubMed     Text format     Abstract available


    June 2016
  21. KUMAR AS, Jagadeeshan S, Subramanian A, Chidambaram SB, et al
    Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor.
    J Biol Chem. 2016;291:12310-21.
    PubMed     Text format     Abstract available


    May 2016
  22. LIU K, Li F, Han H, Chen Y, et al
    Parkin Regulates the Activity of Pyruvate Kinase M2.
    J Biol Chem. 2016;291:10307-17.
    PubMed     Text format     Abstract available


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