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Articles published in J Biol Chem

Retrieve available abstracts of 19 articles:
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Single Articles

    May 2022
  1. PENA-DIAZ S, Pujols J, Vasili E, Pinheiro F, et al
    The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple alpha-synuclein strains.
    J Biol Chem. 2022;298:101902.
    PubMed     Abstract available

    January 2022
  2. XU B, Huang S, Liu Y, Wan C, et al
    Manganese promotes alpha-synuclein amyloid aggregation through the induction of protein phase transition.
    J Biol Chem. 2022;298:101469.
    PubMed     Abstract available

  3. SANGO J, Kakihana T, Takahashi M, Katsuragi Y, et al
    USP10 inhibits the dopamine-induced reactive oxygen species-dependent apoptosis of neuronal cells by stimulating the antioxidant Nrf2 activity.
    J Biol Chem. 2022;298:101448.
    PubMed     Abstract available

    December 2021
  4. LEE SH, Jung S, Lee YJ, Hyun M, et al
    FBXO7 triggers caspase 8-mediated proteolysis of the transcription factor FOXO4 and exacerbates neuronal cytotoxicity.
    J Biol Chem. 2021;297:101426.
    PubMed     Abstract available

    October 2021
  5. GANDELMAN M, Dansithong W, Kales SC, Paul S, et al
    The AKT modulator A-443654 reduces alpha-synuclein expression and normalizes ER stress and autophagy.
    J Biol Chem. 2021;297:101191.
    PubMed     Abstract available

    July 2021
  6. PAN PY, Zhu J, Rizvi A, Zhu X, et al
    Synaptojanin1 deficiency upregulates basal autophagosome formation in astrocytes.
    J Biol Chem. 2021;297:100873.
    PubMed     Abstract available

    June 2021
  7. AMIREDDY N, Puttapaka SN, Vinnakota RL, Ravuri HG, et al
    Correction: The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice.
    J Biol Chem. 2021;297:100864.

    January 2021
  8. WESTON LJ, Stackhouse TL, Spinelli KJ, Boutros SW, et al
    Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies.
    J Biol Chem. 2021;296:100273.
    PubMed     Abstract available

  9. RAMALINGAM N, Dettmer U
    Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons.
    J Biol Chem. 2021;296:100271.
    PubMed     Abstract available

    December 2020
  10. CLARK EH, Vazquez de la Torre A, Hoshikawa T, Briston T, et al
    Targeting mitophagy in Parkinson's disease.
    J Biol Chem. 2020 Dec 23:100209. doi: 10.1074/jbc.REV120.014294.
    PubMed     Abstract available

  11. CLARK EH, Vazquez de la Torre A, Hoshikawa T, Briston T, et al
    Targeting mitophagy in Parkinson's disease.
    J Biol Chem. 2020 Dec 18. pii: REV120.014294. doi: 10.1074/jbc.REV120.014294.
    PubMed     Abstract available

  12. GUINEY SJ, Adlard PA, Lei P, Mawal CH, et al
    Fibrillar alpha-synuclein toxicity depends on functional lysosomes.
    J Biol Chem. 2020;295:17497-17513.
    PubMed     Abstract available

    July 2020
  13. LAUTENSCHLAGER J, Wagner-Valladolid S, Stephens AD, Fernandez-Villegas A, et al
    Intramitochondrial proteostasis is directly coupled to alpha-synuclein and amyloid beta1-42 pathologies.
    J Biol Chem. 2020;295:10138-10152.
    PubMed     Abstract available

    May 2020
  14. LU J, Zhang S, Ma X, Jia C, et al
    Structural basis of the interplay between alpha-synuclein and Tau in regulating pathological amyloid aggregation.
    J Biol Chem. 2020;295:7470-7480.
    PubMed     Abstract available

    February 2020
  15. LEVY DR, Udgata A, Tourlomousis P, Symmons MF, et al
    Parkinson's disease-associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages.
    J Biol Chem. 2020 Feb 28. pii: RA119.011842. doi: 10.1074/jbc.RA119.011842.
    PubMed     Abstract available

    January 2020
  16. KUMARI R, Kumar R, Kumar S, Singh AK, et al
    Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease.
    J Biol Chem. 2020 Jan 31. pii: RA119.009546. doi: 10.1074/jbc.RA119.009546.
    PubMed     Abstract available

  17. FROULA JM, Castellana-Cruz M, Anabtawi NM, Camino JD, et al
    Correction: Defining alpha-synuclein species responsible for Parkinson's disease phenotypes in mice.
    J Biol Chem. 2020;295:1142.

    June 2019
  18. CHATTOPADHYAY M, Chowdhury AR, Feng T, Assenmacher CA, et al
    Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models.
    J Biol Chem. 2019;294:10336-10348.
    PubMed     Abstract available

    April 2019
  19. PONZINI E, De Palma A, Cerboni L, Natalello A, et al
    Methionine oxidation in alpha-synuclein inhibits its propensity for ordered secondary structure.
    J Biol Chem. 2019;294:5657-5665.
    PubMed     Abstract available

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