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  Parkinson's Disease

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Articles published in Neurobiol Dis

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Single Articles


    July 2024
  1. ADOM MA, Hahn WN, McCaffery TD, Moors TE, et al
    Reducing the lipase LIPE in mutant alpha-synuclein mice improves Parkinson-like deficits and reveals sex differences in fatty acid metabolism.
    Neurobiol Dis. 2024;199:106593.
    PubMed     Abstract available


  2. FASANO A, Mure H, Oyama G, Murase N, et al
    Subthalamic nucleus local field potential stability in patients with Parkinson's disease.
    Neurobiol Dis. 2024;199:106589.
    PubMed     Abstract available


    June 2024
  3. MESAROSOVA L, Scheper M, Iyer A, Anink JJ, et al
    miR-193b-3p/ PGC-1alpha pathway regulates an insulin dependent anti-inflammatory response in Parkinson's disease.
    Neurobiol Dis. 2024 Jun 29:106587. doi: 10.1016/j.nbd.2024.106587.
    PubMed     Abstract available


  4. LI X, Pang H, Bu S, Zhao M, et al
    Stage-dependent differential impact of network communication on cognitive function across the continuum of cognitive decline in Parkinson's disease.
    Neurobiol Dis. 2024 Jun 24:106578. doi: 10.1016/j.nbd.2024.106578.
    PubMed     Abstract available


  5. TEZUKA T, Ishiguro M, Taniguchi D, Osogaguchi E, et al
    Clinical characteristics and pathophysiological properties of newly discovered LRRK2 variants associated with Parkinson's disease.
    Neurobiol Dis. 2024 Jun 18:106571. doi: 10.1016/j.nbd.2024.106571.
    PubMed     Abstract available


  6. MASATO A, Bubacco L
    The alphaSynuclein half-life conundrum.
    Neurobiol Dis. 2024;196:106524.
    PubMed     Abstract available


  7. GAO AYL, Montagna DR, Hirst WD, Temkin PA, et al
    RIT2 regulates autophagy lysosomal pathway induction and protects against alpha-synuclein pathology in a cellular model of Parkinson's disease.
    Neurobiol Dis. 2024;199:106568.
    PubMed     Abstract available


  8. BAARBE J, Brown MJN, Saha U, Tran S, et al
    Cortical modulations before lower limb motor blocks are associated with freezing of gait in Parkinson's disease: an EEG source localization study.
    Neurobiol Dis. 2024 Jun 7:106557. doi: 10.1016/j.nbd.2024.106557.
    PubMed     Abstract available


  9. GAN C, Cao X, Sun H, Ye S, et al
    Multimodal neuroimaging fusion unravel structural-functional-neurotransmitter change in Parkinson's disease with impulse control disorders.
    Neurobiol Dis. 2024;198:106560.
    PubMed     Abstract available


  10. LEAVITT D, Alanazi FI, Al-Ozzi TM, Cohn M, et al
    Auditory oddball responses in the human subthalamic nucleus and substantia nigra pars reticulata.
    Neurobiol Dis. 2024;195:106490.
    PubMed     Abstract available


  11. YAN S, Lu J, Duan B, Zhu H, et al
    Quantitative susceptibility mapping of multiple system atrophy and Parkinson's disease correlates with neurotransmitter reference maps.
    Neurobiol Dis. 2024;198:106549.
    PubMed     Abstract available


    May 2024
  12. CASANOVA F, Tian Q, Williamson DS, Qian Y, et al
    MRI-derived brain iron, grey matter volume, and risk of dementia and Parkinson's disease: Observational and genetic analysis in the UK Biobank cohort.
    Neurobiol Dis. 2024 May 22:106539. doi: 10.1016/j.nbd.2024.106539.
    PubMed     Abstract available


  13. GULBERTI A, Schneider TR, Galindo-Leon EE, Heise M, et al
    Premotor cortical beta synchronization and the network neuromodulation of externally paced finger tapping in Parkinson's disease.
    Neurobiol Dis. 2024 May 11:106529. doi: 10.1016/j.nbd.2024.106529.
    PubMed     Abstract available


  14. SHI D, Wu S, Zhuang C, Mao Y, et al
    Multimodal data fusion reveals functional and neurochemical correlates of Parkinson's disease.
    Neurobiol Dis. 2024 May 11:106527. doi: 10.1016/j.nbd.2024.106527.
    PubMed     Abstract available


  15. ILIEVA NM, Hoffman EK, Ghalib MA, Greenamyre JT, et al
    LRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants.
    Neurobiol Dis. 2024 May 3:106522. doi: 10.1016/j.nbd.2024.106522.
    PubMed     Abstract available


  16. HEMBACH S, Schmidt S, Orschmann T, Burtscher I, et al
    Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation.
    Neurobiol Dis. 2024;194:106474.
    PubMed     Abstract available


    April 2024
  17. GUO X, He S, Geng X, Yao P, et al
    Quantifying local field potential dynamics with amplitude and frequency stability between ON and OFF medication and stimulation in Parkinson's disease.
    Neurobiol Dis. 2024 Apr 27:106519. doi: 10.1016/j.nbd.2024.106519.
    PubMed     Abstract available


  18. RURAK BK, Tan J, Rodrigues JP, Power BD, et al
    Cortico-cortical connectivity is influenced by levodopa in tremor-dominant Parkinson's disease.
    Neurobiol Dis. 2024;196:106518.
    PubMed     Abstract available


  19. TREMBLAY C, Aslam S, Walker JE, Lorenzini I, et al
    RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction.
    Neurobiol Dis. 2024 Apr 23:106514. doi: 10.1016/j.nbd.2024.106514.
    PubMed     Abstract available


  20. BUOSO C, Seifert M, Lang M, Griffith CM, et al
    Dopamine?iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease.
    Neurobiol Dis. 2024 Apr 20:106506. doi: 10.1016/j.nbd.2024.106506.
    PubMed     Abstract available


  21. TONG B, Ba Y, Li Z, Yang C, et al
    Targeting dysregulated lipid metabolism for the treatment of Alzheimer's disease and Parkinson's disease: Current advancements and future prospects.
    Neurobiol Dis. 2024 Apr 18:106505. doi: 10.1016/j.nbd.2024.106505.
    PubMed     Abstract available


  22. JIAO LL, Dong HL, Liu MM, Wu PL, et al
    The potential roles of salivary biomarkers in neurodegenerative diseases.
    Neurobiol Dis. 2024;193:106442.
    PubMed     Abstract available


    March 2024
  23. IOVINO L, Vander Zwaag J, Kaur G, Khakpour M, et al
    Investigation of microglial diversity in a LRRK2 G2019S mouse model of Parkinson's disease.
    Neurobiol Dis. 2024 Mar 23:106481. doi: 10.1016/j.nbd.2024.106481.
    PubMed     Abstract available


  24. ZHOU C, You J, Guan X, Guo T, et al
    Microstructural alterations of the hypothalamus in Parkinson's disease and probable REM sleep behavior disorder.
    Neurobiol Dis. 2024 Mar 11:106472. doi: 10.1016/j.nbd.2024.106472.
    PubMed     Abstract available


    February 2024
  25. HUANG YT, Chen YW, Lin TY, Chen JC, et al
    Suppression of presynaptic corticostriatal glutamate activity attenuates L-dopa-induced dyskinesia in 6-OHDA-lesioned Parkinson's disease mice.
    Neurobiol Dis. 2024;193:106452.
    PubMed     Abstract available


  26. STOLL AC, Kemp CJ, Patterson JR, Howe JW, et al
    Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions.
    Neurobiol Dis. 2024;191:106411.
    PubMed     Abstract available


    January 2024
  27. IMARISIO A, Yahyavi I, Avenali M, Di Maio A, et al
    Blood D-serine levels correlate with aging and dopaminergic treatment in Parkinson's disease.
    Neurobiol Dis. 2024;192:106413.
    PubMed     Abstract available


  28. WU C, Wu H, Zhou C, Guan X, et al
    Neurovascular coupling alteration in drug-naive Parkinson's disease: The underlying molecular mechanisms and levodopa's restoration effects.
    Neurobiol Dis. 2024 Jan 8:106406. doi: 10.1016/j.nbd.2024.106406.
    PubMed     Abstract available


  29. SALIN P, Melon C, Chassain C, Gubellini P, et al
    Interhemispheric reactivity of the subthalamic nucleus sustains progressive dopamine neuron loss in asymmetrical parkinsonism.
    Neurobiol Dis. 2024;191:106398.
    PubMed     Abstract available


    December 2023
  30. TRAN S, Heida TC, Heijs JJA, Al-Ozzi T, et al
    Subthalamic and pallidal neurons are modulated during externally cued movements in Parkinson's disease.
    Neurobiol Dis. 2023 Dec 20:106384. doi: 10.1016/j.nbd.2023.106384.
    PubMed     Abstract available


  31. LIANG K, Li X, Guo Q, Ma J, et al
    Structural changes in the retina and serum HMGB1 levels are associated with decreased cognitive function in patients with Parkinson's disease.
    Neurobiol Dis. 2023;190:106379.
    PubMed     Abstract available


  32. DI LAZZARO G, Picca A, Boldrini S, Bove F, et al
    Differential profiles of serum cytokines in Parkinson's disease according to disease duration.
    Neurobiol Dis. 2023 Dec 5:106371. doi: 10.1016/j.nbd.2023.106371.
    PubMed     Abstract available


    November 2023
  33. TSHILENGE KT, Bons J, Aguirre CG, Geronimo-Olvera C, et al
    Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing.
    Neurobiol Dis. 2023 Nov 30:106367. doi: 10.1016/j.nbd.2023.106367.
    PubMed     Abstract available


  34. TOFFOLI M, Chohan H, Mullin S, Jesuthasan A, et al
    Phenotypic effect of GBA1 variants in individuals with and without Parkinson's disease: The RAPSODI study.
    Neurobiol Dis. 2023 Nov 3:106343. doi: 10.1016/j.nbd.2023.106343.
    PubMed     Abstract available


  35. HARVEY J, Pishva E, Chouliaras L, Lunnon K, et al
    Elucidating distinct molecular signatures of Lewy body dementias.
    Neurobiol Dis. 2023;188:106337.
    PubMed     Abstract available


  36. TUBERT C, Zampese E, Pancani T, Tkatch T, et al
    Feed-forward metabotropic signaling by Cav1 Ca(2+) channels supports pacemaking in pedunculopontine cholinergic neurons.
    Neurobiol Dis. 2023;188:106328.
    PubMed     Abstract available


  37. DUES DJ, Ma Y, Nguyen APT, Offerman AV, et al
    Formation of templated inclusions in a forebrain alpha-synuclein mouse model is independent of LRRK2.
    Neurobiol Dis. 2023;188:106338.
    PubMed     Abstract available


    October 2023
  38. RIVAS-SANTISTEBAN R, Rico A, Munoz A, Rodriguez AI, et al
    Boolean analysis shows a high proportion of dopamine D(2) receptors interacting with adenosine A(2A) receptors in striatal medium spiny neurons of mouse and non-human primate models of Parkinson's disease.
    Neurobiol Dis. 2023 Oct 31:106341. doi: 10.1016/j.nbd.2023.106341.
    PubMed     Abstract available


  39. CHEN L, Sun J, Gao L, Wang J, et al
    Dysconnectivity of the parafascicular nucleus in Parkinson's disease: A dynamic causal modeling analysis.
    Neurobiol Dis. 2023;188:106335.
    PubMed     Abstract available


  40. LI T, Liu T, Zhang J, Ma Y, et al
    Neurovascular coupling dysfunction of visual network organization in Parkinson's disease.
    Neurobiol Dis. 2023;188:106323.
    PubMed     Abstract available


  41. MAPLE-GRODEM J, Ushakova A, Pedersen KF, Tysnes OB, et al
    Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach.
    Neurobiol Dis. 2023;186:106281.
    PubMed     Abstract available


  42. SCHAFFNER SL, Wassouf Z, Hentrich T, Nuesch-Germano M, et al
    Distinct impacts of alpha-synuclein overexpression on the hippocampal epigenome of mice in standard and enriched environments.
    Neurobiol Dis. 2023;186:106274.
    PubMed     Abstract available


    September 2023
  43. DE FABREGUES O, Selles M, Ramos-Vicente D, Roch G, et al
    Relevance of tissue-resident memory CD8 T cells in the onset of Parkinson's disease and examination of its possible etiologies: infectious or autoimmune?
    Neurobiol Dis. 2023 Sep 21:106308. doi: 10.1016/j.nbd.2023.106308.
    PubMed     Abstract available


  44. TRINH D, Israwi AR, Brar H, Villafuerte JEA, et al
    Parkinson's disease pathology is directly correlated to SIRT3 in human subjects and animal models: Implications for AAV.SIRT3-myc as a disease-modifying therapy.
    Neurobiol Dis. 2023 Sep 11:106287. doi: 10.1016/j.nbd.2023.106287.
    PubMed     Abstract available


    August 2023
  45. GRONLIER E, Volle J, Coizet V, Paccard A, et al
    Evoked responses to single pulse electrical stimulation reveal impaired striatal excitability in a rat model of Parkinson's disease.
    Neurobiol Dis. 2023 Aug 19:106266. doi: 10.1016/j.nbd.2023.106266.
    PubMed     Abstract available


  46. GAN C, Ji M, Sun H, Cao X, et al
    Dynamic functional connectivity reveals hyper-connected pattern and abnormal variability in freezing of gait of Parkinson's disease.
    Neurobiol Dis. 2023;185:106265.
    PubMed     Abstract available


  47. REN J, Yan L, Zhou H, Pan C, et al
    Unraveling neurotransmitter changes in de novo GBA-related and idiopathic Parkinson's disease.
    Neurobiol Dis. 2023 Aug 7:106254. doi: 10.1016/j.nbd.2023.106254.
    PubMed     Abstract available


  48. DUMONT M, Agostinis A, Singh K, Swan E, et al
    Sex representation in neurodegenerative and psychiatric disorders' preclinical and clinical studies.
    Neurobiol Dis. 2023;184:106214.
    PubMed     Abstract available


  49. BHATIA TN, Jamenis AS, Abbas M, Clark RN, et al
    A 14-day pulse of PLX5622 modifies alpha-synucleinopathy in preformed fibril-infused aged mice of both sexes.
    Neurobiol Dis. 2023;184:106196.
    PubMed     Abstract available


    July 2023
  50. CROCKETT RA, Wilkins KB, Aditham S, Bronte-Stewart HM, et al
    No laughing white matter: Reduced integrity of the cortical cholinergic pathways in Parkinson's disease-related cognitive impairment.
    Neurobiol Dis. 2023 Jul 29:106243. doi: 10.1016/j.nbd.2023.106243.
    PubMed     Abstract available


  51. URSO D, Batzu L, Logroscino G, Chaudhuri KR, et al
    Neurofilament light predicts worse nonmotor symptoms and depression in Parkinson's disease.
    Neurobiol Dis. 2023 Jul 25:106237. doi: 10.1016/j.nbd.2023.106237.
    PubMed     Abstract available


  52. AVANTAGGIATO F, Farokhniaee A, Bandini A, Palmisano C, et al
    Intelligibility of speech in Parkinson's disease relies on anatomically segregated subthalamic beta oscillations.
    Neurobiol Dis. 2023 Jul 25:106239. doi: 10.1016/j.nbd.2023.106239.
    PubMed     Abstract available


  53. WANG Y, Xia Y, Kou L, Yin S, et al
    Astrocyte-to-neuron reprogramming and crosstalk in the treatment of Parkinson's disease.
    Neurobiol Dis. 2023 Jul 9:106224. doi: 10.1016/j.nbd.2023.106224.
    PubMed     Abstract available


  54. LEGAZ A, Prado P, Moguilner S, Baez S, et al
    Social and non-social working memory in neurodegeneration.
    Neurobiol Dis. 2023;183:106171.
    PubMed     Abstract available


    June 2023
  55. WU H, Wu C, Qin J, Zhou C, et al
    Functional connectome predicting individual gait function and its relationship with molecular architecture in Parkinson's disease.
    Neurobiol Dis. 2023;184:106216.
    PubMed     Abstract available


  56. DI MAIO A, Nuzzo T, Gilio L, Serra M, et al
    Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients.
    Neurobiol Dis. 2023 Jun 17:106203. doi: 10.1016/j.nbd.2023.106203.
    PubMed     Abstract available


  57. BATZU L, Urso D, Grothe MJ, Vereb D, et al
    Increased basal forebrain volumes could prevent cognitive decline in LRRK2 Parkinson's disease.
    Neurobiol Dis. 2023 Jun 5:106182. doi: 10.1016/j.nbd.2023.106182.
    PubMed     Abstract available


  58. ZHONG M, Wang Y, Lin G, Liao FF, et al
    Dopamine-independent development and maintenance of mouse striatal medium spiny neuron dendritic spines.
    Neurobiol Dis. 2023;181:106096.
    PubMed     Abstract available


    May 2023
  59. LUCHETTI S, Liere P, Pianos A, Verwer RWH, et al
    Disease stage-dependent changes in brain levels and neuroprotective effects of neuroactive steroids in Parkinson's disease.
    Neurobiol Dis. 2023 May 29:106169. doi: 10.1016/j.nbd.2023.106169.
    PubMed     Abstract available


  60. YIN Z, Jiang Y, Merk T, Neumann WJ, et al
    Pallidal activities during sleep and sleep decoding in dystonia, Huntington's, and Parkinson's disease.
    Neurobiol Dis. 2023 May 3:106143. doi: 10.1016/j.nbd.2023.106143.
    PubMed     Abstract available


  61. FAYARD A, Fenyi A, Lavisse S, Dovero S, et al
    Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates.
    Neurobiol Dis. 2023;180:106086.
    PubMed     Abstract available


  62. CHEN Z, Reynolds RH, Pardinas AF, Gagliano Taliun SA, et al
    The contribution of Neanderthal introgression and natural selection to neurodegenerative diseases.
    Neurobiol Dis. 2023;180:106082.
    PubMed     Abstract available


    April 2023
  63. GUERRA A, Colella D, Cannavacciuolo A, Giangrosso M, et al
    Short-term plasticity of the motor cortex compensates for bradykinesia in Parkinson's disease.
    Neurobiol Dis. 2023;182:106137.
    PubMed     Abstract available


  64. HAYLEY S, Vahid-Ansari F, Sun H, Albert PR, et al
    Mood disturbances in Parkinson's disease: From prodromal origins to application of animal models.
    Neurobiol Dis. 2023 Apr 8:106115. doi: 10.1016/j.nbd.2023.106115.
    PubMed     Abstract available


  65. SASIKUMAR S, Sorrento G, Lang AE, Strafella AP, et al
    Cognition affects gait adaptation after split-belt treadmill training in Parkinson's disease.
    Neurobiol Dis. 2023 Apr 3:106109. doi: 10.1016/j.nbd.2023.106109.
    PubMed     Abstract available


    March 2023
  66. CAULFIELD ME, Vander Werp MJ, Stancati JA, Collier TJ, et al
    Downregulation of striatal Ca(V)1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age.
    Neurobiol Dis. 2023 Mar 29:106111. doi: 10.1016/j.nbd.2023.106111.
    PubMed     Abstract available


  67. HUANG Q, Chen C, Chen W, Cai C, et al
    Cell type- and region-specific translatomes in an MPTP mouse model of Parkinson's disease.
    Neurobiol Dis. 2023;180:106105.
    PubMed     Abstract available


  68. TAN S, Zhou C, Wen J, Duanmu X, et al
    Presence but not the timing of onset of REM sleep behavior disorder distinguishes evolution patterns in Parkinson's disease.
    Neurobiol Dis. 2023;180:106084.
    PubMed     Abstract available


  69. PORRINI V, Pilotto A, Vezzoli M, Lanzillotta A, et al
    NF-kappaB/c-Rel DNA-binding is reduced in substantia nigra and peripheral blood mononuclear cells of Parkinson's disease patients.
    Neurobiol Dis. 2023 Mar 7:106067. doi: 10.1016/j.nbd.2023.106067.
    PubMed     Abstract available


  70. WIEST C, He S, Duchet B, Pogosyan A, et al
    Evoked resonant neural activity in subthalamic local field potentials reflects basal ganglia network dynamics.
    Neurobiol Dis. 2023;178:106019.
    PubMed     Abstract available


  71. LIN S, Leitao ADG, Fang S, Gu Y, et al
    Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy.
    Neurobiol Dis. 2023;178:106010.
    PubMed     Abstract available


    February 2023
  72. MCKAY JL, Nye J, Goldstein FC, Sommerfeld B, et al
    Levodopa responsive freezing of gait is associated with reduced norepinephrine transporter binding in Parkinson's disease.
    Neurobiol Dis. 2023 Feb 20:106048. doi: 10.1016/j.nbd.2023.106048.
    PubMed     Abstract available


    January 2023
  73. ABDI IY, Bartl M, Dakna M, Abdesselem H, et al
    Cross-sectional proteomic expression in Parkinson's disease-related proteins in drug-naive patients vs healthy controls with longitudinal clinical follow-up.
    Neurobiol Dis. 2023 Jan 9:105997. doi: 10.1016/j.nbd.2023.105997.
    PubMed     Abstract available


  74. OUTEIRO TF, El-Agnaf OM
    The immune system in Parkinson's disease: From biology to diagnosis and therapeutic targets.
    Neurobiol Dis. 2023 Jan 7:105995. doi: 10.1016/j.nbd.2023.105995.
    PubMed    


  75. MARTEL AC, Galvan A
    Corrigendum to: "Connectivity of the Corticostriatal and Thalamostriatal Systems in Normal and Parkinsonian States: An Update" Neurobiology of Disease 174: 105878.
    Neurobiol Dis. 2023 Jan 2:105985. doi: 10.1016/j.nbd.2022.105985.
    PubMed    


  76. ESTAUN-PANZANO J, Arotcarena ML, Bezard E
    Monitoring alpha-synuclein aggregation.
    Neurobiol Dis. 2023;176:105966.
    PubMed     Abstract available


  77. DE LAZZARI F, Agostini F, Plotegher N, Sandre M, et al
    DJ-1 promotes energy balance by regulating both mitochondrial and autophagic homeostasis.
    Neurobiol Dis. 2023;176:105941.
    PubMed     Abstract available


  78. CASTELA I, Casado-Polanco R, Rubio YV, da Silva JA, et al
    Selective activation of striatal indirect pathway suppresses levodopa induced-dyskinesias.
    Neurobiol Dis. 2023;176:105930.
    PubMed     Abstract available


    December 2022
  79. LEWITT PA, Li J, Wu KH, Lu M, et al
    Diagnostic metabolomic profiling of Parkinson's disease biospecimens.
    Neurobiol Dis. 2022 Dec 20:105962. doi: 10.1016/j.nbd.2022.105962.
    PubMed     Abstract available


  80. BRENDZA R, Gao X, Stark KL, Lin H, et al
    Anti-alpha-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease.
    Neurobiol Dis. 2022 Dec 16:105969. doi: 10.1016/j.nbd.2022.105969.
    PubMed     Abstract available


  81. LIPARI N, Centner A, Glinski J, Cohen S, et al
    Characterizing the relationship between L-DOPA-induced-dyskinesia and psychosis-like behaviors in a bilateral rat model of Parkinson's disease.
    Neurobiol Dis. 2022;176:105965.
    PubMed     Abstract available


  82. VERMA AK, Yu Y, Acosta-Lenis SF, Havel T, et al
    Parkinsonian daytime sleep-wake classification using deep brain stimulation lead recordings.
    Neurobiol Dis. 2022 Dec 12:105963. doi: 10.1016/j.nbd.2022.105963.
    PubMed     Abstract available


  83. MELONI M, Agliardi C, Guerini FR, Zanzottera M, et al
    Oligomeric alpha-synuclein and tau aggregates in NDEVs differentiate Parkinson's disease from atypical parkinsonisms.
    Neurobiol Dis. 2022 Dec 5:105947. doi: 10.1016/j.nbd.2022.105947.
    PubMed     Abstract available


  84. GOPINATH A, Mackie PM, Phan LT, Tansey MG, et al
    The complex role of inflammation and gliotransmitters in Parkinson's disease.
    Neurobiol Dis. 2022 Dec 2:105940. doi: 10.1016/j.nbd.2022.105940.
    PubMed     Abstract available


  85. GAERTNER Z, Azcorra M, Dombeck DA, Awatramani R, et al
    Molecular heterogeneity in the substantia nigra: A roadmap for understanding PD motor pathophysiology.
    Neurobiol Dis. 2022;175:105925.
    PubMed     Abstract available


  86. TAI CH, Tseng SH
    Cerebellar deep brain stimulation for movement disorders.
    Neurobiol Dis. 2022;175:105899.
    PubMed     Abstract available


    November 2022
  87. WISE RM, Wagener A, Fietzek UM, Klopstock T, et al
    Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders.
    Neurobiol Dis. 2022;175:105920.
    PubMed     Abstract available


  88. SARKAR S
    Microglial ion channels: Key players in non-cell autonomous neurodegeneration.
    Neurobiol Dis. 2022;174:105861.
    PubMed     Abstract available


    October 2022
  89. CHO E, Kim K, Kim H, Cho SR, et al
    Reelin protects against pathological alpha-synuclein accumulation and dopaminergic neurodegeneration after environmental enrichment in Parkinson's disease.
    Neurobiol Dis. 2022 Oct 18:105898. doi: 10.1016/j.nbd.2022.105898.
    PubMed     Abstract available


  90. PUIGROS M, Calderon A, Perez-Soriano A, de Dios C, et al
    Cell-free mitochondrial DNA deletions in idiopathic, but not LRRK2, Parkinson's disease.
    Neurobiol Dis. 2022;174:105885.
    PubMed     Abstract available


  91. RYU DW, Yoo SW, Oh YS, Lee KS, et al
    Comparison of disease progression between brain-predominant Parkinson's disease versus Parkinson's disease with body-involvement phenotypes.
    Neurobiol Dis. 2022;174:105883.
    PubMed     Abstract available


  92. EVANS RC
    Dendritic involvement in inhibition and disinhibition of vulnerable dopaminergic neurons in healthy and pathological conditions.
    Neurobiol Dis. 2022;172:105815.
    PubMed     Abstract available


    September 2022
  93. MARTEL AC, Galvan A
    Connectivity of the corticostriatal and thalamostriatal systems in normal and parkinsonian states: An update.
    Neurobiol Dis. 2022;174:105878.
    PubMed     Abstract available


  94. RUF WP, Palmer A, Dorfer L, Wiesner D, et al
    Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease.
    Neurobiol Dis. 2022 Sep 23:105877. doi: 10.1016/j.nbd.2022.105877.
    PubMed     Abstract available


  95. ZANG NAM, Schneider M, Weiss D
    Cortical mechanisms of movement recovery after freezing in Parkinson's disease.
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  96. STOLL AC, Sortwell CE
    Leveraging the preformed fibril model to distinguish between alpha-synuclein inclusion- and nigrostriatal degeneration-associated immunogenicity.
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    August 2022
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    Oxidative stress and synaptic dysfunction in rodent models of Parkinson's disease.
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  99. WILLIAMS ET, Chen X, Otero PA, Moore DJ, et al
    Understanding the contributions of VPS35 and the retromer in neurodegenerative disease.
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  100. ERDMAN HB, Kornilov E, Kahana E, Zarchi O, et al
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    July 2022
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    The modulatory effect of self-paced and cued motor execution on subthalamic beta-bursts in Parkinson's disease: Evidence from deep brain recordings in humans.
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  102. TIAN Y, Pan L, Yuan X, Xiong M, et al
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  104. BURMEISTER AR, Gordevicius J, Paul EN, Houck C, et al
    Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring.
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    June 2022
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    The role of LRRK2 in the periphery: link with Parkinson's disease and inflammatory diseases.
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    Mitochondrial electron transport chain defects modify Parkinson's disease phenotypes in a Drosophila model.
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  108. MANTIA K, Kostas V, Katerina M
    The promise of the TGF-beta superfamily as a therapeutic target for Parkinson's disease.
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    Age-dependent neurodegeneration and neuroinflammation in a genetic A30P/A53T double-mutated alpha-synuclein mouse model of Parkinson's disease.
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    Dopamine depletion can be predicted by the aperiodic component of subthalamic local field potentials.
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    May 2022
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    Gut microbial metabolites in Parkinson's disease: Association with lifestyle, disease characteristics, and treatment status.
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  112. SONG B, Feldmann JW, Cao S, Feitosa M, et al
    A Pitx3-deficient developmental mouse model for fine motor, olfactory, and gastrointestinal symptoms of Parkinson's disease.
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  113. ABDI IY, Ghanem SS, El-Agnaf OM
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  114. KEENEY MT, Hoffman EK, Farmer K, Bodle CR, et al
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    Evidence for immune system alterations in peripheral biological fluids in Parkinson's disease.
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  116. IZCO M, Carlos E, Alvarez-Erviti L
    Impact of endolysosomal dysfunction upon exosomes in neurodegenerative diseases.
    Neurobiol Dis. 2022;166:105651.
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    April 2022
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    Convergence of signalling pathways in innate immune responses and genetic forms of Parkinson's disease.
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    March 2022
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  119. WEISS F, Labrador-Garrido A, Dzamko N, Halliday G, et al
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    The roles of connectivity and neuronal phenotype in determining the pattern of alpha-synuclein pathology in Parkinson's disease.
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  121. SHEN W, Zhai S, Surmeier DJ
    Striatal synaptic adaptations in Parkinson's disease.
    Neurobiol Dis. 2022 Mar 7:105686. doi: 10.1016/j.nbd.2022.105686.
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  122. COUSINEAU J, Plateau V, Baufreton J, Le Bon-Jego M, et al
    Dopaminergic modulation of primary motor cortex: From cellular and synaptic mechanisms underlying motor learning to cognitive symptoms in Parkinson's disease.
    Neurobiol Dis. 2022 Mar 1:105674. doi: 10.1016/j.nbd.2022.105674.
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    February 2022
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  124. BOCCALINI C, Carli G, Pilotto A, Padovani A, et al
    Gender differences in dopaminergic system dysfunction in de novo Parkinson's disease clinical subtypes.
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  125. GEGG ME, Menozzi E, Schapira AHV
    Glucocerebrosidase-associated Parkinson disease: Pathogenic mechanisms and potential drug treatments.
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  126. KASEN A, Houck C, Burmeister AR, Sha Q, et al
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    January 2022
  127. HORSAGER J, Knudsen K, Sommerauer M
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    Neurobiol Dis. 2022 Jan 11:105626. doi: 10.1016/j.nbd.2022.105626.
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  128. WOERMAN AL, Tamguney G
    Body-first Parkinson's disease and variant Creutzfeldt-Jakob disease - similar or different?
    Neurobiol Dis. 2022 Jan 10:105625. doi: 10.1016/j.nbd.2022.105625.
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    December 2021
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    Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease.
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  132. SCHILDER BM, Navarro E, Raj T
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    November 2021
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  137. FERRER-RAVENTOS P, Beyer K
    Alternative platelet activation pathways and their role in neurodegenerative diseases.
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    Heterozygous GBA D409V and ATP13a2 mutations do not exacerbate pathological alpha-synuclein spread in the prodromal preformed fibrils model in young mice.
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    Genetic ablation of Gpnmb does not alter synuclein-related pathology.
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    October 2021
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    Molecular chaperones and Parkinson's disease.
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    August 2021
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    Neurophysiological responses of globus pallidus internus during the auditory oddball task in Parkinson's disease.
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    Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease.
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  146. OLSEN AL, Feany MB
    Parkinson's disease risk genes act in glia to control neuronal alpha-synuclein toxicity.
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    Behavioral and neurochemical studies of inherited manganese-induced dystonia-parkinsonism in Slc39a14-knockout mice.
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    July 2021
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    Anticipatory human subthalamic area beta-band power responses to dissociable tastes correlate with weight gain.
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    June 2021
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    Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism.
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    May 2021
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    Subthalamic nucleus deep brain stimulation induces sustained neurorestoration in the mesolimbic dopaminergic system in a Parkinson's disease model.
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  151. TOMKINS JE, Manzoni C
    Advances in protein-protein interaction network analysis for Parkinson's disease.
    Neurobiol Dis. 2021;155:105395.
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  152. BRAZHNIK E, Novikov N, McCoy AJ, Ilieva NM, et al
    Early decreases in cortical mid-gamma peaks coincide with the onset of motor deficits and precede exaggerated beta build-up in rat models for Parkinson's disease.
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    In vivo aggregation of presynaptic alpha-synuclein is not influenced by its phosphorylation at serine-129.
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  154. WIEST C, Tinkhauser G, Pogosyan A, He S, et al
    Subthalamic deep brain stimulation induces finely-tuned gamma oscillations in the absence of levodopa.
    Neurobiol Dis. 2021;152:105287.
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    April 2021
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    Local field potentials in Parkinson's disease: a frequency-based review.
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    Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease.
    Neurobiol Dis. 2021 Apr 20:105368. doi: 10.1016/j.nbd.2021.105368.
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    March 2021
  157. BRUMBERG J, Kuzkina A, Lapa C, Mammadova S, et al
    Dermal and cardiac autonomic fiber involvement in Parkinson's disease and multiple system atrophy.
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  158. CHU Y, Kordower JH
    GDNF signaling in subjects with minimal motor deficits and Parkinson's disease.
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  159. ZOU L, Zhang X, Xiong M, Meng L, et al
    Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
    Neurobiol Dis. 2021 Mar 4:105326. doi: 10.1016/j.nbd.2021.105326.
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  160. CREED RB, Roberts RC, Farmer CB, McMahon LL, et al
    Increased glutamate transmission onto dorsal striatum spiny projection neurons in Pink1 knockout rats.
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    February 2021
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    Impaired neurogenesis in the hippocampus of an adult VPS35 mutant mouse model of Parkinson's disease through interaction with APP.
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    The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease.
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    January 2021
  164. SENCHUK MM, Van Raamsdonk JM, Moore DJ
    Multiple genetic pathways regulating lifespan extension are neuroprotective in a G2019S LRRK2 nematode model of Parkinson's disease.
    Neurobiol Dis. 2021 Jan 12:105267. doi: 10.1016/j.nbd.2021.105267.
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    A population scale analysis of rare SNCA variation in the UK Biobank.
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    Dopaminergic denervation impairs cortical motor and associative/limbic information processing through the basal ganglia and its modulation by the CB1 receptor.
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    December 2020
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    Exosome-mediated delivery of antisense oligonucleotides targeting alpha-synuclein ameliorates the pathology in a mouse model of Parkinson's disease.
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    November 2020
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    Neuroimaging and neuropathology studies of X-linked dystonia parkinsonism.
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    Primary motor cortex in Parkinson's disease: Functional changes and opportunities for neurostimulation.
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    October 2020
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    Gait variability is linked to the atrophy of the Nucleus Basalis of Meynert and is resistant to STN DBS in Parkinson's disease.
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    September 2020
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    June 2020
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