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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 32 articles:
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Single Articles


    March 2019
  1. SHEN HH
    Core Concept: Can deep brain stimulation find success beyond Parkinson's disease?
    Proc Natl Acad Sci U S A. 2019;116:4764-4766.
    PubMed     Text format    


  2. CHEN X, Kordich JK, Williams ET, Levine N, et al
    Parkinson's disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration.
    Proc Natl Acad Sci U S A. 2019 Mar 6. pii: 1814909116.
    PubMed     Text format     Abstract available


    January 2019
  3. LEVINE PM, Galesic A, Balana AT, Mahul-Mellier AL, et al
    alpha-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2019 Jan 16. pii: 1808845116.
    PubMed     Text format     Abstract available


    December 2018
  4. YAN R, Zhang J, Park HJ, Park ES, et al
    Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
    Proc Natl Acad Sci U S A. 2018 Dec 3. pii: 1813365115.
    PubMed     Text format     Abstract available


    November 2018
  5. BRESKA A, Ivry RB
    Double dissociation of single-interval and rhythmic temporal prediction in cerebellar degeneration and Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 Nov 13. pii: 1810596115.
    PubMed     Text format     Abstract available


    October 2018
  6. GUO JF, Zhang L, Li K, Mei JP, et al
    Coding mutations in NUS1 contribute to Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 Oct 22. pii: 1809969115.
    PubMed     Text format     Abstract available


  7. PUJOLS J, Pena-Diaz S, Lazaro DF, Peccati F, et al
    Small molecule inhibits alpha-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
    Proc Natl Acad Sci U S A. 2018;115:10481-10486.
    PubMed     Text format     Abstract available


    September 2018
  8. LEE KS, Huh S, Lee S, Wu Z, et al
    Altered ER-mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease models.
    Proc Natl Acad Sci U S A. 2018;115:E8844-E8853.
    PubMed     Text format     Abstract available


    August 2018
  9. TELKES I, Viswanathan A, Jimenez-Shahed J, Abosch A, et al
    Local field potentials of subthalamic nucleus contain electrophysiological footprints of motor subtypes of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 Aug 21. pii: 1810589115.
    PubMed     Text format     Abstract available


    July 2018
  10. RUGGERI FS, Benedetti F, Knowles TPJ, Lashuel HA, et al
    Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid alpha-synuclein fibrils.
    Proc Natl Acad Sci U S A. 2018;115:7230-7235.
    PubMed     Text format     Abstract available


    May 2018
  11. BORLONGAN CV
    Fatty acid chemical mediator provides insights into the pathology and treatment of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 May 30. pii: 1807276115.
    PubMed     Text format    


  12. KIM KS, Marcogliese PC, Yang J, Callaghan SM, et al
    Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 May 14. pii: 1718946115.
    PubMed     Text format     Abstract available


  13. NGUYEN M, Krainc D
    LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 May 7. pii: 1717590115.
    PubMed     Text format     Abstract available


  14. REN Q, Ma M, Yang J, Nonaka R, et al
    Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 May 7. pii: 1802179115.
    PubMed     Text format     Abstract available


    March 2018
  15. KUMAR J, Erana H, Lopez-Martinez E, Claes N, et al
    Detection of amyloid fibrils in Parkinson's disease using plasmonic chirality.
    Proc Natl Acad Sci U S A. 2018 Mar 12. pii: 1721690115.
    PubMed     Text format     Abstract available


    February 2018
  16. GRASSI D, Howard S, Zhou M, Diaz-Perez N, et al
    Identification of a highly neurotoxic alpha-synuclein species inducing mitochondrial damage and mitophagy in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2018 Feb 27. pii: 1713849115.
    PubMed     Text format     Abstract available


    January 2018
  17. KIM S, Yun SP, Lee S, Umanah GE, et al
    GBA1 deficiency negatively affects physiological alpha-synuclein tetramers and related multimers.
    Proc Natl Acad Sci U S A. 2018;115:798-803.
    PubMed     Text format     Abstract available


    December 2017
  18. WOERMAN AL, Kazmi SA, Patel S, Aoyagi A, et al
    Familial Parkinson's point mutation abolishes multiple system atrophy prion replication.
    Proc Natl Acad Sci U S A. 2017 Dec 26. pii: 1719369115.
    PubMed     Text format     Abstract available


  19. BRAGG DC, Mangkalaphiban K, Vaine CA, Kulkarni NJ, et al
    Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1.
    Proc Natl Acad Sci U S A. 2017 Dec 11. pii: 1712526114.
    PubMed     Text format     Abstract available


    September 2017
  20. KANG SS, Zhang Z, Liu X, Manfredsson FP, et al
    TrkB neurotrophic activities are blocked by alpha-synuclein, triggering dopaminergic cell death in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201713969.
    PubMed     Text format     Abstract available


  21. THAKUR P, Breger LS, Lundblad M, Wan OW, et al
    Modeling Parkinson's disease pathology by combination of fibril seeds and alpha-synuclein overexpression in the rat brain.
    Proc Natl Acad Sci U S A. 2017 Sep 12. pii: 201710442.
    PubMed     Text format     Abstract available


    June 2017
  22. TURRIANI E, Lazaro DF, Ryazanov S, Leonov A, et al
    Treatment with diphenyl-pyrazole compound anle138b/c reveals that alpha-synuclein protects melanoma cells from autophagic cell death.
    Proc Natl Acad Sci U S A. 2017 Jun 5. pii: 201700200.
    PubMed     Text format     Abstract available


    April 2017
  23. KOUROUPI G, Taoufik E, Vlachos IS, Tsioras K, et al
    Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease.
    Proc Natl Acad Sci U S A. 2017 Apr 17. pii: 201617259.
    PubMed     Text format     Abstract available



  24. Editorial Expression of Concern: Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27.
    Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201704295.
    PubMed     Text format    


    March 2017
  25. KIM KS
    Toward neuroprotective treatments of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2017 Mar 30. pii: 201703362.
    PubMed     Text format    


  26. SPATHIS AD, Asvos X, Ziavra D, Karampelas T, et al
    Nurr1:RXRalpha heterodimer activation as monotherapy for Parkinson's disease.
    Proc Natl Acad Sci U S A. 2017 Mar 27. pii: 201616874.
    PubMed     Text format     Abstract available


  27. MOLLENHAUER B, Weintraub D
    The depressed brain in Parkinson's disease: Implications for an inflammatory biomarker.
    Proc Natl Acad Sci U S A. 2017 Mar 10. pii: 201700737.
    PubMed     Text format    


    February 2017
  28. DUNN AR, Stout KA, Ozawa M, Lohr KM, et al
    Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease.
    Proc Natl Acad Sci U S A. 2017 Feb 28. pii: 201616892.
    PubMed     Text format     Abstract available


    January 2017
  29. GREEN H, Zhang X, Tiklova K, Volakakis N, et al
    Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2017 Jan 30. pii: 201621218.
    PubMed     Text format     Abstract available


  30. PARK Y, Hoang QQ
    Combating Parkinson's disease-associated toxicity by modulating proteostasis.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201620082.
    PubMed     Text format    


    October 2016
  31. HORVATH I, Wittung-Stafshede P
    Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson's disease.
    Proc Natl Acad Sci U S A. 2016 Oct 17. pii: 201610371.
    PubMed     Text format     Abstract available


    April 2016
  32. PINOTSI D, Michel CH, Buell AK, Laine RF, et al
    Nanoscopic insights into seeding mechanisms and toxicity of alpha-synuclein species in neurons.
    Proc Natl Acad Sci U S A. 2016;113:3815-9.
    PubMed     Text format     Abstract available


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