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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 37 articles:
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Single Articles


    October 2022
  1. WANG X, Rimal S, Tantray I, Geng J, et al
    Prevention of ribosome collision-induced neuromuscular degeneration by SARS CoV-2-encoded Nsp1.
    Proc Natl Acad Sci U S A. 2022;119:e2202322119.
    PubMed     Abstract available


  2. MORTEN MJ, Sirvio L, Rupawala H, Mee Hayes E, et al
    Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies.
    Proc Natl Acad Sci U S A. 2022;119:e2205591119.
    PubMed     Abstract available


    September 2022
  3. KAM TI, Park H, Chou SC, Van Vranken JG, et al
    Amelioration of pathologic alpha-synuclein-induced Parkinson's disease by irisin.
    Proc Natl Acad Sci U S A. 2022;119:e2204835119.
    PubMed     Abstract available


    August 2022
  4. SCHERER M, Steiner LA, Kalia SK, Hodaie M, et al
    Single-neuron bursts encode pathological oscillations in subcortical nuclei of patients with Parkinson's disease and essential tremor.
    Proc Natl Acad Sci U S A. 2022;119:e2205881119.
    PubMed     Abstract available


  5. MURRAY KA, Hu CJ, Griner SL, Pan H, et al
    De novo designed protein inhibitors of amyloid aggregation and seeding.
    Proc Natl Acad Sci U S A. 2022;119:e2206240119.
    PubMed     Abstract available


    July 2022
  6. PARMAR M
    Targets for astrocyte-based treatments of Parkinson's disease (PD).
    Proc Natl Acad Sci U S A. 2022;119:e2208876119.
    PubMed    


  7. YANG Y, Song JJ, Choi YR, Kim SH, et al
    Therapeutic functions of astrocytes to treat alpha-synuclein pathology in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2022;119:e2110746119.
    PubMed     Abstract available


  8. DEEN MC, Zhu Y, Gros C, Na N, et al
    A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells.
    Proc Natl Acad Sci U S A. 2022;119:e2200553119.
    PubMed     Abstract available


    June 2022
  9. ENINGER T, Muller SA, Bacioglu M, Schweighauser M, et al
    Signatures of glial activity can be detected in the CSF proteome.
    Proc Natl Acad Sci U S A. 2022;119:e2119804119.
    PubMed     Abstract available


    May 2022
  10. ADAM EM, Brown EN, Kopell N, McCarthy MM, et al
    Deep brain stimulation in the subthalamic nucleus for Parkinson's disease can restore dynamics of striatal networks.
    Proc Natl Acad Sci U S A. 2022;119:e2120808119.
    PubMed     Abstract available


    April 2022
  11. STANDAERT DG, Childers GM
    Alpha-synuclein-mediated DNA damage, STING activation, and neuroinflammation in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2022;119:e2204058119.
    PubMed    


  12. HINKLE JT, Patel J, Panicker N, Karuppagounder SS, et al
    STING mediates neurodegeneration and neuroinflammation in nigrostriatal alpha-synucleinopathy.
    Proc Natl Acad Sci U S A. 2022;119:e2118819119.
    PubMed     Abstract available


    March 2022
  13. AZEVEDO C, Teku G, Pomeshchik Y, Reyes JF, et al
    Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties.
    Proc Natl Acad Sci U S A. 2022;119:e2111405119.
    PubMed     Abstract available


  14. KIM J, Gao Y, Zhao Z, Rodrigues D, et al
    A deep eutectic-based, self-emulsifying subcutaneous depot system for apomorphine therapy in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  15. SUN CP, Zhou JJ, Yu ZL, Huo XK, et al
    Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  16. SINGH RK, Soliman A, Guaitoli G, Stormer E, et al
    Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    February 2022
  17. AYERS JI, Lee J, Monteiro O, Woerman AL, et al
    Different alpha-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  18. KILLINGER BA, Marshall LL, Chatterjee D, Chu Y, et al
    In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  19. HEREMANS IP, Caligiore F, Gerin I, Bury M, et al
    Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021

  20. Correction to Supporting Information for Ahuja et al., Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    November 2021
  21. AHUJA M, Ammal Kaidery N, Attucks OC, McDade E, et al
    Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  22. FOUGERE M, van der Zouwen CI, Boutin J, Neszvecsko K, et al
    Optogenetic stimulation of glutamatergic neurons in the cuneiform nucleus controls locomotion in a mouse model of Parkinson's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  23. VOS M, Dulovic-Mahlow M, Mandik F, Frese L, et al
    Ceramide accumulation induces mitophagy and impairs beta-oxidation in PINK1 deficiency.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  24. SCHEIDT T, Carozza JA, Kolbe CC, Aprile FA, et al
    The binding of the small heat-shock protein alphaB-crystallin to fibrils of alpha-synuclein is driven by entropic forces.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  25. FRANCO A, Gracia P, Colom A, Camino JD, et al
    All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of alpha-synuclein toxic species.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  26. TOYAMA Y, Harkness RW, Kay LE
    Dissecting the role of interprotomer cooperativity in the activation of oligomeric high-temperature requirement A2 protein.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  27. ZHANG S, Liu YQ, Jia C, Lim YJ, et al
    Mechanistic basis for receptor-mediated pathological alpha-synuclein fibril cell-to-cell transmission in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  28. TISZA MJ, Buck CB
    A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  29. LONG H, Zheng W, Liu Y, Sun Y, et al
    Wild-type alpha-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  30. YANG X, Wang B, Hoop CL, Williams JK, et al
    NMR unveils an N-terminal interaction interface on acetylated-alpha-synuclein monomers for recruitment to fibrils.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  31. TRUDLER D, Nazor KL, Eisele YS, Grabauskas T, et al
    Soluble alpha-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  32. SOBU Y, Wawro PS, Dhekne HS, Yeshaw WM, et al
    Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  33. REBELO D, Oliveira F, Abrunhosa A, Januario C, et al
    A link between synaptic plasticity and reorganization of brain activity in Parkinson's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  34. APICCO DJ, Shlevkov E, Nezich CL, Tran DT, et al
    The Parkinson's disease-associated gene ITPKB protects against alpha-synuclein aggregation by regulating ER-to-mitochondria calcium release.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  35. VRIJSEN S, Besora-Casals L, van Veen S, Zielich J, et al
    ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress.
    Proc Natl Acad Sci U S A. 2020;117:31198-31207.
    PubMed     Abstract available


    October 2020
  36. BREKK OR, Honey JR, Lee S, Hallett PJ, et al
    Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.
    Proc Natl Acad Sci U S A. 2020 Oct 15. pii: 2003021117.
    PubMed     Abstract available


  37. MOR DE, Sohrabi S, Kaletsky R, Keyes W, et al
    Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria.
    Proc Natl Acad Sci U S A. 2020 Oct 6. pii: 2009838117.
    PubMed     Abstract available


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