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Pulmonary Hypertension

Free Subscription Articles published in Am J Physiol Lung Cell Mol Physiol Retrieve available abstracts of 47 articles: HTML format

Single Articles

October 2025
1. THAPA S, Sarkar P, Gaber MW, Barrios R, et al
   Adrenomedullin Overexpression Protects Mice from Experimental Bronchopulmonary Dysplasia and Associated Pulmonary Hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2025 Oct 13. doi: 10.1152/ajplung.00234.2025
   PubMed     Abstract available
   
   
   June 2025
2. IMAKIIRE S, Kimuro K, Yoshida K, Masaki K, et al
   Activated Factor X Inhibition Ameliorates NF-kappaB-IL-6?Mediated Perivascular Inflammation and Pulmonary Hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2025 Jun 13. doi: 10.1152/ajplung.00303.2024
   PubMed     Abstract available
   
   
   
3. LEWIS CV, Nguyen TN, Porfilio TE, Burciaga SD, et al
   Vascular EC-SOD limits the accumulation, proinflammatory profibrotic reprogramming, and hyaluronan binding of interstitial macrophages in hypoxia.
   Am J Physiol Lung Cell Mol Physiol. 2025;328:L885-L900.
   PubMed     Abstract available
   
   
   
4. MORA MASSAD K, Dai Z, Petrache I, Ventetuolo CE, et al
   Lung endothelial cell heterogeneity in health and pulmonary vascular disease.
   Am J Physiol Lung Cell Mol Physiol. 2025;328:L877-L884.
   PubMed     Abstract available
   
   
   May 2025
5. GONYEA CR, Shen Y, Nelson KM, Bird RN, et al
   The nitrofen/bisdiamine murine model of congenital diaphragmatic hernia has a pulmonary hypertension vascular phenotype consistent with human CDH.
   Am J Physiol Lung Cell Mol Physiol. 2025 May 30. doi: 10.1152/ajplung.00233.2024
   PubMed     Abstract available
   
   
   April 2025
6. SINGH N, Oldham WM
   Targeting Type-2 Inflammation in Pulmonary Hypertension: Lessons from a Novel Model.
   Am J Physiol Lung Cell Mol Physiol. 2025 Apr 7. doi: 10.1152/ajplung.00109.2025.
   PubMed    
   
   
   March 2025
7. COOKSON MW, Gonzalez T, Bye EM, Seedorf G, et al
   Intraamniotic Vitamin D Preserves Lung Development and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia due to Intraamniotic sFlt-1.
   Am J Physiol Lung Cell Mol Physiol. 2025 Mar 24. doi: 10.1152/ajplung.00409.2024
   PubMed     Abstract available
   
   
   
8. BIRNHUBER A, Biasin V, Jain PP, Kwiatkowski G, et al
   Pulmonary vascular remodeling in Fra-2 transgenic mice is driven by type 2 inflammation and accompanied by pulmonary vascular hyperresponsiveness.
   Am J Physiol Lung Cell Mol Physiol. 2025;328:L413-L429.
   PubMed     Abstract available
   
   
   February 2025
9. ADAO R, Barreira B, Paternoster E, Morales-Cano D, et al
   Vitamin D as an add-on therapy to phosphodiesterase-5 inhibitor in experimental pulmonary arterial hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2025;328:L253-L259.
   PubMed     Abstract available
   
   
   January 2025
10. RAO RJ, Yang J, Jiang S, El-Khoury W, et al
    Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2025;328:L148-L158.
    PubMed     Abstract available
    
    
    December 2024
11. MARINHO Y, Villarreal ES, Loya O, Oliveira SD, et al
    Mechanisms of lung endothelial cell injury and survival in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024;327:L972-L983.
    PubMed     Abstract available
    
    
    October 2024
12. ZHENG Q, Cabrera JTO, Tsuji-Hosokawa A, Ramirez FJ, et al
    Enhanced lung endothelial glycolysis is implicated in the development of severe pulmonary hypertension in type 2 diabetes.
    Am J Physiol Lung Cell Mol Physiol. 2024 Oct 22. doi: 10.1152/ajplung.00305.2023
    PubMed     Abstract available
    
    
    
13. WANG S, Awad KS, Chen LY, Siddique MAH, et al
    Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2alpha.
    Am J Physiol Lung Cell Mol Physiol. 2024;327:L503-L519.
    PubMed     Abstract available
    
    
    September 2024
14. MICKAEL C, Jordan M, Posey JN, Tuder RM, et al
    Activation of Platelets and the Complement System in Mice with Schistosoma-Induced Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024 Sep 10. doi: 10.1152/ajplung.00165.2024
    PubMed     Abstract available
    
    
    August 2024
15. VALUPARAMPIL VARGHESE M, James J, Bharti D, Rischard F, et al
    Circulating free heme induces cytokine storm and pulmonary hypertension through the MKK3/p38 axis.
    Am J Physiol Lung Cell Mol Physiol. 2024 Aug 28. doi: 10.1152/ajplung.00422.2022
    PubMed     Abstract available
    
    
    
16. BROWNSTEIN AJ, Mura M, Ruffenach G, Channick RN, et al
    "Dissecting the Lung Transcriptome of Pulmonary Fibrosis-associated Pulmonary Hypertension".
    Am J Physiol Lung Cell Mol Physiol. 2024 Aug 13. doi: 10.1152/ajplung.00166.2024
    PubMed     Abstract available
    
    
    
17. TUINEAU MN, Herbert LM, Garcia SM, Resta TC, et al
    Enhanced glycolysis causes extracellular acidification and activates acid-sensing ion channel 1a in hypoxic pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024 Aug 6. doi: 10.1152/ajplung.00083.2024.
    PubMed     Abstract available
    
    
    July 2024
18. STEPPAN J, Wang H, Nandakumar K, Gadkari M, et al
    LOXL2 inhibition ameliorates pulmonary artery remodeling in pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024 Jul 16. doi: 10.1152/ajplung.00327.2023
    PubMed     Abstract available
    
    
    
19. CHOVANEC M, Durisova J, Vajnerova O, Banasova A, et al
    Simple model of pulmonary hypertension secondary to left heart pressure overload induced by partial intravascular occlusion of the ascending aorta.
    Am J Physiol Lung Cell Mol Physiol. 2024 Jul 16. doi: 10.1152/ajplung.00243.2023
    PubMed     Abstract available
    
    
    
20. MENEZES TCF, Fonseca Balladares DC, Nolan K, Graham BB, et al
    Two hits strike out causing persistent pulmonary hypertension in mice.
    Am J Physiol Lung Cell Mol Physiol. 2024 Jul 16. doi: 10.1152/ajplung.00198.2024
    PubMed    
    
    
    
21. COURSEN JC, Tuhy T, Naranjo M, Woods A, et al
    Aberrant long-chain fatty acid metabolism associated with evolving systemic sclerosis-associated pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024;327:L54-L64.
    PubMed     Abstract available
    
    
    
22. HEISE EL, Salman J, Webs KS, Hoffler K, et al
    Hypoxic perfusion of pulmonary arterial vasa vasorum increases pulmonary arterial pressure.
    Am J Physiol Lung Cell Mol Physiol. 2024;327:L79-L85.
    PubMed     Abstract available
    
    
    June 2024
23. KUDRYASHOVA TV, Zaitsev SV, Jiang L, Buckley BJ, et al
    PAI-1 Deficiency Drives Pulmonary Vascular Smooth Muscle Remodeling and Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024 Jun 11. doi: 10.1152/ajplung.00110.2024
    PubMed     Abstract available
    
    
    May 2024
24. SUN XQ, Klouda T, Barnasconi S, Schalij I, et al
    Pneumonectomy combined with SU5416 or monocrotaline pyrrole does not cause severe pulmonary hypertension in mice.
    Am J Physiol Lung Cell Mol Physiol. 2024 May 29. doi: 10.1152/ajplung.00105.2024
    PubMed     Abstract available
    
    
    
25. MUTGAN AC, Radic N, Valzano F, Crnkovic S, et al
    A comprehensive map of proteoglycan expression and deposition in the pulmonary arterial wall in health and pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024 May 21. doi: 10.1152/ajplung.00022.2024
    PubMed     Abstract available
    
    
    
26. GUTOR SS, Salinas RI, Nichols DS, Bazzano JMR, et al
    Repetitive sulfur dioxide exposure in mice models post-deployment respiratory syndrome.
    Am J Physiol Lung Cell Mol Physiol. 2024;326:L539-L550.
    PubMed     Abstract available
    
    
    
27. NIEDERMEYER S, Yun X, Trujillo M, Jiang H, et al
    A novel interaction between aquaporin 1 and caspase-3 in pulmonary arterial smooth muscle cells.
    Am J Physiol Lung Cell Mol Physiol. 2024;326:L638-L645.
    PubMed     Abstract available
    
    
    April 2024
28. HATABAH D, De Marco T, McGlothlin DP, Malloy M, et al
    Low global arginine bioavailability: a common phenomenon in pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024;326:L514-L515.
    PubMed    
    
    
    
29. ALI M, Choudhary R, Singh K, Kumari S, et al
    Hypobaric hypoxia modulated structural characteristics of circulating cell-free DNA in high-altitude pulmonary edema.
    Am J Physiol Lung Cell Mol Physiol. 2024;326:L496-L507.
    PubMed     Abstract available
    
    
    March 2024
30. PHILIP N, Yun X, Pi H, Murray S, et al
    Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2024;326:L252-L265.
    PubMed     Abstract available
    
    
    November 2023
31. SIMPSON CE, Ambade AS, Harlan R, Roux A, et al
    Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2023;325:L617-L627.
    PubMed     Abstract available
    
    
    October 2023
32. BARNES EA, Ito R, Che X, Alvira CM, et al
    Loss of Prolyl Hydroxylase 1 and 2 in SM22alpha-Expressing Cells Prevents Hypoxia-Induced Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2023 Oct 17. doi: 10.1152/ajplung.00428.2022
    PubMed     Abstract available
    
    
    
33. LINGAPPAN K, Olutoye OO 2nd, Cantu A, Cantu Gutierrez ME, et al
    Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia.
    Am J Physiol Lung Cell Mol Physiol. 2023;325:L477-L486.
    PubMed     Abstract available
    
    
    September 2023
34. PANKOKE S, Schweitzer T, Bikker R, Pich A, et al
    Obesity impacts hypoxia adaptation of the lung.
    Am J Physiol Lung Cell Mol Physiol. 2023;325:L352-L359.
    PubMed     Abstract available
    
    
    
35. ALMAZROUE H, Jin Y, Nelin LD, Barba JC 2nd, et al
    Human pulmonary microvascular endothelial cell DDAH1-mediated nitric oxide production promotes pulmonary smooth muscle cell apoptosis in co-culture.
    Am J Physiol Lung Cell Mol Physiol. 2023;325:L360-L367.
    PubMed     Abstract available
    
    
    August 2023
36. MASSON B, Saint-Martin Willer A, Dutheil M, Penalva L, et al
    Contribution of transient receptor potential canonical channels in human and experimental pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2023;325:L246-L261.
    PubMed     Abstract available
    
    
    June 2023
37. DOUGHERTY EJ, Chen LY, Awad KS, Ferreyra GA, et al
    Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L783-L798.
    PubMed     Abstract available
    
    
    
38. SIMPSON CE, Coursen J, Hsu S, Gough EK, et al
    Metabolic profiling of in vivo right ventricular function and exercise performance in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L836-L848.
    PubMed     Abstract available
    
    
    May 2023
39. BIGNARD J, Atassi F, Claude O, Ghigna MR, et al
    T-cell dysregulation and inflammatory process in Gcn2 (Eif2ak4(-/-))-deficient rats in basal and stress conditions.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L609-L624.
    PubMed     Abstract available
    
    
    April 2023
40. GILBERT RM, Gleghorn JP
    Connecting clinical, environmental, and genetic factors point to an essential role for vitamin A signaling in the pathogenesis of congenital diaphragmatic hernia.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L456-L467.
    PubMed     Abstract available
    
    
    November 2022
41. SURESH K
    Sex as a biologic variable: evidence from isolated lung endothelial cells.
    Am J Physiol Lung Cell Mol Physiol. 2022;323:L646-L647.
    PubMed    
    
    
    August 2022
42. OSHITA H, Sawada H, Mitani Y, Tsuboya N, et al
    Perinatal hypoxia aggravates occlusive pulmonary vasculopathy in SU5416/hypoxia-treated rats later in life.
    Am J Physiol Lung Cell Mol Physiol. 2022;323:L178-L192.
    PubMed     Abstract available
    
    
    July 2022
43. CAMPBELL NV, Mickael C, Kumar S, Zhang H, et al
    Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia.
    Am J Physiol Lung Cell Mol Physiol. 2022;323:L58-L68.
    PubMed     Abstract available
    
    
    June 2022
44. LEE MH, Sanders L, Kumar R, Hernandez-Saavedra D, et al
    Contribution of Fatty Acid Oxidation to the Pathogenesis of Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2022 Jun 28. doi: 10.1152/ajplung.00039.2022
    PubMed     Abstract available
    
    
    May 2022
45. CHEN J, Rodriguez M, Miao J, Liao J, et al
    Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation.
    Am J Physiol Lung Cell Mol Physiol. 2022;322:L737-L760.
    PubMed     Abstract available
    
    
    March 2022
46. MAARMAN GJ
    Reviewing the suitability of mitochondrial transplantation as therapeutic approach for pulmonary hypertension in the era of personalised medicine.
    Am J Physiol Lung Cell Mol Physiol. 2022 Mar 23. doi: 10.1152/ajplung.00484.2021
    PubMed     Abstract available
    
    
    
47. LU M, Chen LY, Gairhe S, Mazer AJ, et al
    Mineralocorticoid receptor antagonist treatment of established pulmonary arterial hypertension improves interventricular dependence in the SU5416-hypoxia rat model.
    Am J Physiol Lung Cell Mol Physiol. 2022;322:L315-L332.
    PubMed     Abstract available
    
    

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