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  Pulmonary Hypertension

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Articles published in Am J Respir Crit Care Med

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Single Articles


    April 2024
  1. BJORKMAN KR, Miles KG, Bellew LE, Schneider KA, et al
    Patent Ductus Arteriosus and Lung MRI Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2024 Apr 3. doi: 10.1164/rccm.202310-1733.
    PubMed     Abstract available


    March 2024
  2. HARDER E, Abtin F, Nardelli P, Brownstein A, et al
    Pulmonary Hypertension in Idiopathic Interstitial Pneumonia Is Associated with Small Vessel Pruning.
    Am J Respir Crit Care Med. 2024 Mar 19. doi: 10.1164/rccm.202312-2343.
    PubMed    


  3. JAIN A, Epelbaum O
    Synchronous Pulmonary Arterial and Pulmonary Venous Thrombosis in Pancreatic Cancer.
    Am J Respir Crit Care Med. 2024;209:751-752.
    PubMed    


  4. LILEY J, Newnham M, Bleda M, Bunclark K, et al
    Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.
    Am J Respir Crit Care Med. 2024 Mar 12. doi: 10.1164/rccm.202307-1236.
    PubMed     Abstract available


    February 2024
  5. KUDRYASHOVA TV, Jiang L, Goncharova EA
    What Is All of the Hype About? Hypusine Signaling as a Driver of Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2024 Feb 27. doi: 10.1164/rccm.202401-0195.
    PubMed    


  6. NAEIJE R, Tonelli AR
    Pulmonary Artery Wedge Pressure in the Diagnosis of Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2024;209:242-244.
    PubMed    


  7. HARDER EM, Divo MJ, Washko GR, Leopold JA, et al
    Implications of Mean Pulmonary Arterial Wedge Pressure Trajectories in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2024;209:316-324.
    PubMed     Abstract available


    January 2024
  8. RAJAGOPAL S, Yu YR
    Determining the Architecture of Inflammation in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2024;209:131-133.
    PubMed    


  9. FERRIAN S, Cao A, McCaffrey EF, Saito T, et al
    Single-Cell Imaging Maps Inflammatory Cell Subsets to Pulmonary Arterial Hypertension Vasculopathy.
    Am J Respir Crit Care Med. 2024;209:206-218.
    PubMed     Abstract available


    December 2023
  10. YASUMA T, Fujimoto H, D'Alessandro-Gabazza CN, Gabazza EC, et al
    Epoprostenol and Treprostinil: Differential Effects on Regulatory T-Cell Generation in Patients with Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2023;208:1248.
    PubMed    


  11. WEATHERALD J, Moutchia J, Al-Naamani N, McClelland RL, et al
    Win Statistics in Pulmonary Arterial Hypertension Clinical Trials.
    Am J Respir Crit Care Med. 2023;208:1231-1234.
    PubMed    


    September 2023
  12. GUO M, Wikenheiser-Brokamp KA, Kitzmiller JA, Jiang C, et al
    Single Cell Multiomics Identifies Cells and Genetic Networks Underlying Alveolar Capillary Dysplasia.
    Am J Respir Crit Care Med. 2023;208:709-725.
    PubMed     Abstract available


  13. NORLANDER AE, Abney M, Cephus JY, Roe CE, et al
    Prostaglandin I(2) Therapy Promotes Regulatory T Cell Generation in Patients with Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2023;208:737-739.
    PubMed    


  14. FARHA S, Aldred MA
    Regulating the Regulators: Epigenetic Modulation of Regulatory T-Cells in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2023 Sep 8. doi: 10.1164/rccm.202308-1456.
    PubMed    


    August 2023
  15. ROCHESTER CL, Alison JA, Carlin B, Jenkins AR, et al
    Pulmonary Rehabilitation for Adults with Chronic Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline.
    Am J Respir Crit Care Med. 2023;208:e7-e26.
    PubMed     Abstract available


  16. HAN MK
    From Conundrum to Cures, Pioneering Breakthroughs in Chronic Obstructive Pulmonary Disease Research: Introduction to an AJRCCM Special Issue.
    Am J Respir Crit Care Med. 2023;208:339-340.
    PubMed    


  17. BRITTAIN EL, Tedford RJ, Maron BA
    Reply to: Can Pulmonary Arterial Compliance Be a Prognostic Marker for Pulmonary Hypertension?
    Am J Respir Crit Care Med. 2023 Aug 10. doi: 10.1164/rccm.202307-1180.
    PubMed    


  18. WU Y, Su X, Wang J, Zhang H, et al
    Can Pulmonary Arterial Compliance Be a Prognostic Marker for Pulmonary Hypertension?
    Am J Respir Crit Care Med. 2023 Aug 10. doi: 10.1164/rccm.202306-1076.
    PubMed    


  19. FORBES LM, Bull TM, Lahm T, Lawley JS, et al
    Right Ventricular Response to Acute Hypoxia among Healthy Humans.
    Am J Respir Crit Care Med. 2023;208:333-336.
    PubMed    


    July 2023
  20. JOHNSON S, Sommer N, Cox-Flaherty K, Weissmann N, et al
    Pulmonary Hypertension: A Contemporary Review.
    Am J Respir Crit Care Med. 2023 Jul 14. doi: 10.1164/rccm.202302-0327.
    PubMed     Abstract available


  21. LEIVA O, Garcia BD, Hobbs G
    Pulmonary Hypertension in Myeloproliferative Neoplasms: New Insights and Unexplored Horizons.
    Am J Respir Crit Care Med. 2023 Jul 10. doi: 10.1164/rccm.202306-1001.
    PubMed    


    June 2023
  22. WEATHERALD J, Zanini U, Humbert M
    Illuminating the Importance of Pulmonary Arterial Compliance in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2023 Jun 22. doi: 10.1164/rccm.202306-0990.
    PubMed    


  23. MARON BA
    Introducing the Pulmonary Hypertension Thematic Series.
    Am J Respir Crit Care Med. 2023 Jun 21. doi: 10.1164/rccm.202306-1005.
    PubMed    


  24. SONNTAG E, Akgun KM, Bag R, Rosensweig EB, et al
    Access to Medically Necessary Reproductive Care for Individuals with Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2023 Jun 13. doi: 10.1164/rccm.202302-0230.
    PubMed    


  25. MONTANI D, Thore P, Mignard X, Jais X, et al
    Clinical Phenotype and Outcomes of Pulmonary Hypertension Associated with Myeloproliferative Neoplasms: A Population-based Study.
    Am J Respir Crit Care Med. 2023 Jun 13. doi: 10.1164/rccm.202210-1941.
    PubMed     Abstract available


  26. WANG RS, Huang S, Waldo SW, Hess E, et al
    Elevated Pulmonary Arterial Compliance Is Associated with Survival in Pulmonary Hypertension: Results from a Novel Network Medicine Analysis.
    Am J Respir Crit Care Med. 2023 Jun 5. doi: 10.1164/rccm.202211-2097.
    PubMed     Abstract available


  27. YANAGIHARA T, Tsubouchi K, Zhou Q, Chong M, et al
    Vascular-Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling.
    Am J Respir Crit Care Med. 2023;207:1498-1514.
    PubMed     Abstract available


    May 2023
  28. QUARCK R, Bogaard HJ, Delcroix M
    The Cellular Landscape of Chronic Thromboembolic Pulmonary Hypertension Revealed by Single-Cell Sequencing: Therapeutic Implications?
    Am J Respir Crit Care Med. 2023;207:1266-1268.
    PubMed    


  29. NATHAN SD
    Progress in the Treatment of Pulmonary Hypertension Associated with Interstitial Lung Disease.
    Am J Respir Crit Care Med. 2023 May 9. doi: 10.1164/rccm.202212-2342.
    PubMed     Abstract available


  30. BRUSATORI S, Zinnato C, Busana M, Romitti F, et al
    High- versus Low-Flow Extracorporeal Respiratory Support in Experimental Hypoxemic Acute Lung Injury.
    Am J Respir Crit Care Med. 2023;207:1183-1193.
    PubMed     Abstract available


    April 2023
  31. ULRICH S
    A Further Step Toward Meaningful Trial Outcomes for Patients with Pulmonary Arterial Hypertension: Minimal Important Difference in 6-minute-walk Distance.
    Am J Respir Crit Care Med. 2023;207:972-974.
    PubMed    


  32. VANDERPOOL RR, Insel M, Kubba S, Rischard FP, et al
    The Acute Effects of Prostacyclin on Right Ventricular Contractility and Pulmonary Artery Coupling.
    Am J Respir Crit Care Med. 2023;207:1100-1102.
    PubMed    


  33. MOUTCHIA J, McClelland RL, Al-Naamani N, Appleby DH, et al
    Minimal Clinically Important Difference in the 6-minute-walk Distance for Patients with Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2023;207:1070-1079.
    PubMed     Abstract available


  34. CORNFIELD DN, Nogee LM
    Rare to "Ubiquitinous": Alveolar Capillary Dysplasia, FOXF1, and a Sly Approach to Angiogenesis.
    Am J Respir Crit Care Med. 2023;207:969-971.
    PubMed    


  35. PRADHAN A, Che L, Ustiyan V, Reza AA, et al
    Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia.
    Am J Respir Crit Care Med. 2023;207:1042-1054.
    PubMed     Abstract available


  36. MCNAMARA PJ, Lakshminrusimha S
    Maldevelopment of the Immature Pulmonary Vasculature and Prolonged Patency of the Ductus Arteriosus: Association or Cause?
    Am J Respir Crit Care Med. 2023;207:814-816.
    PubMed    


    March 2023
  37. LIN S, Frank DB
    SOX17 at the Intersection of Sex, Transcription, and Metabolism in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2023 Mar 16. doi: 10.1164/rccm.202302-0284.
    PubMed    


  38. OLIVEIRA SD
    Cardiopulmonary Pathogenic Networks: Unveiling the Gut-Lung Microbiome Axis in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2023;207:655-657.
    PubMed    


  39. MOUTSOGLOU DM, Tatah J, Prisco SZ, Prins KW, et al
    Pulmonary Arterial Hypertension Patients Have a Proinflammatory Gut Microbiome and Altered Circulating Microbial Metabolites.
    Am J Respir Crit Care Med. 2023;207:740-756.
    PubMed     Abstract available


  40. SANGAM S, Sun X, Schwantes-An TH, Yegambaram M, et al
    SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics.
    Am J Respir Crit Care Med. 2023 Mar 13. doi: 10.1164/rccm.202203-0450.
    PubMed     Abstract available



  41. Erratum: Prognostic Value of Exercise as Compared to Resting Pulmonary Hypertension in Patients with Normal or Mildly Elevated Pulmonary Arterial Pressure.
    Am J Respir Crit Care Med. 2023;207:636.
    PubMed    


    February 2023
  42. VISWANATHAN G, Kirshner HF, Nazo N, Ali S, et al
    Single-Cell Analysis Reveals Distinct Immune and Smooth Muscle Cell Populations that Contribute to Chronic Thromboembolic Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2023 Feb 21. doi: 10.1164/rccm.202203-0441.
    PubMed     Abstract available


  43. XANTHOULI P
    Improved Survival for Patients with Systemic Sclerosis-associated Pulmonary Arterial Hypertension: For Real?
    Am J Respir Crit Care Med. 2023;207:238-240.
    PubMed    


  44. GOLDBERG HJ
    Comparing the Incomparable: Identifying Common Themes Across a Diverse Landscape to Address Equity in Lung Allocation.
    Am J Respir Crit Care Med. 2023;207:236-238.
    PubMed    


  45. HASSAN HJ, Naranjo M, Ayoub N, Housten T, et al
    Improved Survival for Patients with Systemic Sclerosis-associated Pulmonary Arterial Hypertension: The Johns Hopkins Registry.
    Am J Respir Crit Care Med. 2023;207:312-322.
    PubMed     Abstract available


  46. KOLAITIS NA, Chen H, Calabrese DR, Kumar K, et al
    The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision.
    Am J Respir Crit Care Med. 2023;207:300-311.
    PubMed     Abstract available


    January 2023
  47. WANG ZH, Zhou Q
    Targeting Pulmonary Hypertension Caused by Pulmonary Fibrosis: A Promising NKT Cell-based Therapy.
    Am J Respir Crit Care Med. 2023 Jan 13. doi: 10.1164/rccm.202211-2134.
    PubMed    


  48. JANDL K, Marsh LM, Mutgan AC, Crnkovic S, et al
    Reply to: Targeting Pulmonary Hypertension Caused by Pulmonary Fibrosis: A Promising NKT Cell-based Therapy.
    Am J Respir Crit Care Med. 2023 Jan 13. doi: 10.1164/rccm.202212-2214.
    PubMed    


  49. RAFFAY TM, Jensen EA
    Can Intermittent Hypoxemia Help Detect Pulmonary Hypertension in High-Risk Preemies?
    Am J Respir Crit Care Med. 2023 Jan 11. doi: 10.1164/rccm.202212-2290.
    PubMed    


    December 2022
  50. DOUSCHAN P, Avian A, Foris V, Sassmann T, et al
    Prognostic Value of Exercise as Compared to Resting Pulmonary Hypertension in Patients with Normal or Mildly Elevated Pulmonary Arterial Pressure.
    Am J Respir Crit Care Med. 2022;206:1418-1423.
    PubMed    


    November 2022
  51. GENTLE SJ, Travers CP, Nakhmani A, Indic P, et al
    Intermittent Hypoxemia and Bronchopulmonary Dysplasia with Pulmonary Hypertension in Preterm Infants.
    Am J Respir Crit Care Med. 2022 Nov 30. doi: 10.1164/rccm.202203-0580.
    PubMed     Abstract available


  52. GENTLE SJ, Travers CP, Clark M, Carlo WA, et al
    Patent Ductus Arteriosus and Development of Bronchopulmonary Dysplasia with Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Nov 15. doi: 10.1164/rccm.202203-0570.
    PubMed     Abstract available


    October 2022
  53. MONTANI D, Weatherald J, Humbert M, Sitbon O, et al
    Reply to: Effect of Covid-19 Infection in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Oct 17. doi: 10.1164/rccm.202210-1889.
    PubMed    


  54. JHA AK
    Effect of Covid-19 Infection in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Oct 17. doi: 10.1164/rccm.202209-1790.
    PubMed    


  55. TAYLOR S, Isobe S, Cao A, Contrepois K, et al
    Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;206:1019-1034.
    PubMed     Abstract available


    September 2022
  56. AL-QAZAZI R, Lima PDA, Prisco SZ, Potus F, et al
    Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;206:608-624.
    PubMed     Abstract available


  57. BELHAJ A, Dewachter L, Hupkens E, Remmelink M, et al
    Tacrolimus Prevents Mechanical and Humoral Alterations in Brain Death-induced Lung Injury in Pigs.
    Am J Respir Crit Care Med. 2022;206:584-595.
    PubMed     Abstract available


    August 2022
  58. COTTIN V, Selman M, Inoue Y, Wong AW, et al
    Syndrome of Combined Pulmonary Fibrosis and Emphysema: An Official ATS/ERS/JRS/ALAT Research Statement.
    Am J Respir Crit Care Med. 2022;206:e7-e41.
    PubMed     Abstract available



  59. Erratum: Prediction of Health-related Quality of Life and Hospitalization in Pulmonary Arterial Hypertension: The Pulmonary Hypertension Association Registry.
    Am J Respir Crit Care Med. 2022;206:362-363.
    PubMed    


    July 2022
  60. YUAN P, Li J, Liu J, Liu H, et al
    Cognitive Dysfunction in Patients with Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Jul 29. doi: 10.1164/rccm.202204-0726.
    PubMed    


  61. WERTHEIM BM
    New Tricks for an Old Drug: Prostacyclins and Right Ventricular Contractility in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;206:12-13.
    PubMed    


  62. FRECH TM, Austin ED
    Is It Still "Idiopathic"? Features of Autoimmunity in Idiopathic Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;206:8-10.
    PubMed    


  63. JONES RJ, De Bie EMDD, Groves E, Zalewska KI, et al
    Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;206:81-93.
    PubMed     Abstract available


    June 2022
  64. HERSI K, Elinoff JM
    Pulmonary Hypertension due to Interstitial Lung Disease: A New iNKlinig into Disease Pathobiology.
    Am J Respir Crit Care Med. 2022 Jun 30. doi: 10.1164/rccm.202206-1186.
    PubMed    


  65. JANDL K, Marsh LM, Mutgan AC, Crnkovic S, et al
    Impairment of the NKT-STAT1-CXCL9-axis Contributes to Vessel Fibrosis in Pulmonary Hypertension Due to Lung Fibrosis.
    Am J Respir Crit Care Med. 2022 Jun 28. doi: 10.1164/rccm.202201-0142.
    PubMed     Abstract available


  66. ABMAN SH, Mullen MP
    Of Registries and Disease Classification: Unmasking the Challenges of Pediatric Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Jun 23. doi: 10.1164/rccm.202206-1180.
    PubMed    


  67. OKAZAKI A, Kinuya K, Fujimoto M
    Diffuse Decreased Blood Flow in the Right Lung: Mitral Regurgitation-Induced Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Jun 23. doi: 10.1164/rccm.202110-2339.
    PubMed    


  68. SOBRANO FAIS R, Lahm T
    Misbehaving Guests in the Right Ventricle: Macrophage NLRP3 Activation in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Jun 15. doi: 10.1164/rccm.202205-0977.
    PubMed    


  69. SIMPSON CE, Hassoun PM
    Promises and Pitfalls of Multiomics Approaches to Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;205:1377-1379.
    PubMed    


  70. HARBAUM L, Rhodes CJ, Wharton J, Lawrie A, et al
    Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;205:1449-1460.
    PubMed     Abstract available


  71. PRZEBINDA AS, El Haj Chehade A, Farooqui SM, Youness HA, et al
    Assessment of Pulmonary Vascular Disease: Pulmonary Vascular Resistance, Exercise Hemodynamics, and Ventriculovascular Coupling.
    Am J Respir Crit Care Med. 2022;205:1349.
    PubMed    


  72. PROVENCHER S, Potus F, Blais-Lecours P, Bernard S, et al
    BET Protein Inhibition for Pulmonary Arterial Hypertension: A Pilot Clinical Trial.
    Am J Respir Crit Care Med. 2022;205:1357-1360.
    PubMed    


    May 2022
  73. LAPATRA T, Baird GL, Goodman R, Pinder D, et al
    Reply to: Remote 6-minute Walk Testing in Patients with Pulmonary Hypertension: Further Validation Needed?
    Am J Respir Crit Care Med. 2022 May 24. doi: 10.1164/rccm.202205-0867.
    PubMed    


  74. HELGESON SA, Burger CD, Moss JE, Zeiger TK, et al
    Remote 6-minute Walk Testing in Patients with Pulmonary Hypertension: Further Validation Needed?
    Am J Respir Crit Care Med. 2022 May 24. doi: 10.1164/rccm.202204-0762.
    PubMed    


  75. ALBA GA
    Double Jeopardy: Precapillary Pulmonary Hypertension Increases the Risk of Hospitalization and Death from COVID-19.
    Am J Respir Crit Care Med. 2022 May 18. doi: 10.1164/rccm.202205-0884.
    PubMed    


  76. CONSTANTINE A, Dimopoulos K, Haworth SG, Muthurangu V, et al
    Twenty-year experience and outcomes in a National Pediatric Pulmonary Hypertension Service.
    Am J Respir Crit Care Med. 2022 May 17. doi: 10.1164/rccm.202110-2428.
    PubMed     Abstract available


  77. JIN Q, Guan L, Pan W, Zhang X, et al
    Inhaled Treprostinil after Initial Clinical Worsening: To Continue or Not to Continue, That's the Question.
    Am J Respir Crit Care Med. 2022;205:1250-1251.
    PubMed    


  78. MONTANI D, Certain MC, Weatherald J, Jais X, et al
    COVID-19 in Patients with Pulmonary Hypertension: A National Prospective Cohort Study.
    Am J Respir Crit Care Med. 2022 May 12. doi: 10.1164/rccm.202112-2761.
    PubMed     Abstract available


  79. RAO R, Chan SY
    A dUTY to Protect: Addressing "Y" We See Sex Differences in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 May 12. doi: 10.1164/rccm.202204-0653.
    PubMed    


  80. CUNNINGHAM CM, Li M, Ruffenach G, Doshi M, et al
    Y-Chromosome Gene, Uty, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines.
    Am J Respir Crit Care Med. 2022 May 3. doi: 10.1164/rccm.202110-2309.
    PubMed     Abstract available


  81. SINGH N, Ventetuolo CE
    Prime Time for Proteomics in Pulmonary Arterial Hypertension Risk Assessment?
    Am J Respir Crit Care Med. 2022;205:988-990.
    PubMed    


  82. RHODES CJ, Wharton J, Swietlik EM, Harbaum L, et al
    Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;205:1102-1111.
    PubMed     Abstract available


    April 2022
  83. TELLO K, Kremer N, Richter MJ, Gall H, et al
    Inhaled Iloprost Improves Right Ventricular Load-Independent Contractility in Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Apr 15. doi: 10.1164/rccm.202201-0095.
    PubMed    


  84. MINHAS J, Baird G, Appleby D, McClelland R, et al
    Terminal Digit Preference in Pulmonary Hypertension Endpoints.
    Am J Respir Crit Care Med. 2022 Apr 5. doi: 10.1164/rccm.202108-2015.
    PubMed    


  85. VIZZA CD, Lang IM, Badagliacca R, Benza RL, et al
    Aggressive Afterload Lowering to Improve the Right Ventricle: A New Target for Medical Therapy in Pulmonary Arterial Hypertension?
    Am J Respir Crit Care Med. 2022;205:751-760.
    PubMed     Abstract available


    February 2022
  86. KOLAITIS NA, Lammi M, Mazimba S, Feldman J, et al
    Human Immune Deficiency Virus-Associated Pulmonary Arterial Hypertension: A Report from the Pulmonary Hypertension Association Registry.
    Am J Respir Crit Care Med. 2022 Feb 18. doi: 10.1164/rccm.202111-2481.
    PubMed    


  87. SHARMA S, Lang IM
    More Evidence for Inflammatory Thrombosis in Chronic Thromboembolic Pulmonary Hypertension - Is the Embolic Hypothesis Losing Grounds?
    Am J Respir Crit Care Med. 2022 Feb 8. doi: 10.1164/rccm.202201-0001.
    PubMed    


  88. EVRARD B, Goudelin M, Vaidie J, Fedou AL, et al
    Severe Acute Cor Pulmonale in COVID-19 ARDS Patients: Caution with Left Turn.
    Am J Respir Crit Care Med. 2022 Feb 4. doi: 10.1164/rccm.202107-1568.
    PubMed    


    January 2022
  89. MANZ XD, Szulcek R, Pan X, Symersky P, et al
    Epigenetic Modification of the VWF Promotor Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension.
    Am J Respir Crit Care Med. 2022 Jan 26. doi: 10.1164/rccm.202109-2075.
    PubMed     Abstract available


  90. BEHR J
    Inhaled Treprostinil in Pulmonary Hypertension in the Context of Interstitial Lung Disease: A Success, Finally.
    Am J Respir Crit Care Med. 2022;205:144-145.
    PubMed    


  91. LAPATRA T, Baird GL, Goodman R, Pinder D, et al
    Remote Six-Minute Walk Testing in Patients with Pulmonary Hypertension: A Pilot Study.
    Am J Respir Crit Care Med. 2022 Jan 11. doi: 10.1164/rccm.202110-2421.
    PubMed    


  92. MOUTSOGLOU DM
    2021 American Thoracic Society BEAR Cage Winning Proposal: Microbiome Transplant in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2022;205:13-16.
    PubMed    


    December 2021
  93. JIN Q, Guan L, Pan W, Zhou D, et al
    Initial Triple Combination Therapy for Intermediate-and High-Risk Pulmonary Arterial Hypertension: Standard of Care or Still Too Soon to Tell?
    Am J Respir Crit Care Med. 2021;204:1491-1492.
    PubMed    


  94. RAHAGHI FN, Trieu M, Shaikh F, Abtin F, et al
    Evolution of Obstructive Lung Function in Advanced Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2021;204:1478-1481.
    PubMed    


  95. DIEFFENBACH PB, Mallarino Haeger C, Rehman R, Corcoran AM, et al
    A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature.
    Am J Respir Crit Care Med. 2021;204:1433-1451.
    PubMed     Abstract available


  96. MARVIN-PEEK J, Hemnes A, Huang S, Silverman-Loyd L, et al
    Daily Step Counts Are Associated with Hospitalization Risk in Pulmonary Arterial Hypertension.
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    November 2021
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  98. NATHAN SD, Tapson VF, Elwing J, Rischard F, et al
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  99. SUN X, Chen R, Yao X, Zheng Z, et al
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    October 2021
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  102. GONCHAROVA EA, Kudryashova TV, Maroli G, Pullamsetti SS, et al
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  103. CASCINO TM, McLaughlin VV
    Upfront Combination Therapy for Pulmonary Arterial Hypertension: Time to Be More Ambitious than AMBITION.
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  104. HASSOUN PM, Farber HW
    Hit Early and Hit Hard in Pulmonary Arterial Hypertension? Not So Fast!
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  105. BOUCLY A, Savale L, Jais X, Bauer F, et al
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    September 2021
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    August 2021
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    July 2021
  109. ZHANG Y, Michelakis ED
    A Phase-2 NIH-sponsored Randomized Clinical Trial of Rituximab in Scleroderma-associated Pulmonary Arterial Hypertension Did Not Reach Significance for Its Endpoints: End of Story? Not So Fast!
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    June 2021
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    April 2021
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  115. MORELL E, Gaies M, Fineman JR, Charpie J, et al
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    March 2021
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    Surrogate Markers for Pulmonary Hypertension May Inform Prognosis in Lung Cancer.
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  117. WANG J, Yang K, Yuan JX
    NEDD9, a Hypoxia-upregulated Mediator for Pathogenic Platelet-endothelial Cell Interaction in Pulmonary Hypertension.
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  118. SOCKRIDER M, Roessel L, Fagan KA, Gillespie M, et al
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  119. VIELE K, Girard TD
    Risk, Results, and Costs: Optimizing Clinical Trial Efficiency through Prognostic Enrichment.
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  120. HUMBERT M, Lau EMT
    Risk Stratification in Pulmonary Arterial Hypertension: Do Not Forget the Patient Perspective.
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  121. SCOTT JV, Garnett CE, Kanwar MK, Stockbridge NL, et al
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    What Is Pulmonary Hypertension?
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  123. AGARWAL S, de Jesus Perez VA
    In Defense of the Nucleus: NUDT1 and Oxidative DNA Damage in Pulmonary Arterial Hypertension.
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    February 2021
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    RNA Methylation: A New Regulator of Vascular Remodeling in Pulmonary Hypertension.
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  126. BADAGLIACCA R, D'Alto M, Ghio S, Vizza CD, et al
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  127. WEATHERALD J, Boucly A, Savale L, Jais X, et al
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  128. SCHOENBERG NC, Farber HW
    When "AMBITION" Isn't Good Enough: Risk Status and Dual Oral Therapy in Pulmonary Arterial Hypertension.
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  129. KHURAL JS, Houston BA, Leary PJ, Mathai SC, et al
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  130. BADAGLIACCA R, D'Alto M, Ghio S, Argiento P, et al
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  131. KARNES JH, Schwantes-An TH, Kittles R, Desai AA, et al
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  132. NON AL, Chang SY
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  133. HIRAIDE T, Teratani T, Uemura S, Yoshimatsu Y, et al
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    January 2021
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  135. RODRIGUEZ-LOPEZ J, Wright CD, Stone JR, Farber H, et al
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  136. SYNN AJ, Li W, San Jose Estepar R, Washko GR, et al
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  137. EUL B, Cekay M, Pullamsetti SS, Tello K, et al
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    December 2020
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    Knocking Out Smoking and Pulmonary Hypertension with a K().
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  139. ALDRED MA
    PHorecasting Heritable Pulmonary Arterial Hypertension: Are We Nearly There Yet?
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  140. AMIN EK, Austin ED, Parker C, Colglazier E, et al
    Novel Documentation of Onset and Rapid Advancement of Pulmonary Arterial Hypertension without Symptoms in BMPR2 Mutation Carriers: Cautionary Tales?
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    November 2020
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  142. CHELLADURAI P, Savai R, Pullamsetti SS
    Zooming into Cellular and Molecular Heterogeneity of Pulmonary Hypertension: What More Single-cell Omics Can Offer.
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  143. MISNER K, Kass DJ
    A Plot TWIST in Pulmonary Arterial Hypertension.
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    October 2020
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    Pulmonary Arterial Hypertension and Sex in the Right Ventricle: It Is an Interesting Picture!
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  145. TELLO K, Richter MJ, Yogeswaran A, Ghofrani HA, et al
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    September 2020
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    August 2020
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    Clarifying the Pulmonary Arterial Hypertension Molecular Landscape Using Functional Genetics.
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  148. RHODES CJ, Otero-Nunez P, Wharton J, Swietlik EM, et al
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    July 2020
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    A New "TYK" Tok Era for the Study of Long Non-Coding RNAs in Pulmonary Hypertension.
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  150. FAN Y, Gu X, Zhang J, Sinn K, et al
    TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2.
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  151. RUOPP NF, Farber HW
    The Elephant Man Meets Pulmonary Hypertension: A Cautionary Tale.
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  152. BOTROS L, Szulcek R, Jansen SMA, Kurakula K, et al
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  153. ZEHENDNER CM, Valasarajan C, Werner A, Boeckel JN, et al
    Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-Mediated Regulation of PDGFRbeta.
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  154. GONCHAROVA EA, Chan SY, Ventetuolo CE, Weissmann N, et al
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    June 2020
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    BMP9/10 in Pulmonary Vascular Complications of Liver Disease.
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  156. AUSTIN ED, Hamid R
    Deconstructing the Melting Pot in Pulmonary Arterial Hypertension.
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  157. KARNES JH, Wiener HW, Schwantes-An TH, Natarajan B, et al
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    May 2020
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  159. ALVAREZ RA, Berra L, Gladwin MT
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  161. GONCHAROVA EA, Simon MA, Yuan JX
    mTORC1 in Pulmonary Arterial Hypertension. At the Crossroads between Vasoconstriction and Vascular Remodeling?
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  164. PLOSA EJ, Benjamin JT
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    March 2020
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    Reply to: Emphysema is - at the most - only a Mild Phenotype in the Sugen-Hypoxia Rat Model of Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2019 Aug 22. doi: 10.1164/rccm.201907-1367.
    PubMed    


    June 2019
  198. GRINNAN D, Farkas L
    A Novel Peptide for Immunomodulation in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2019;199:1460-1461.
    PubMed    


  199. GOLDENBERG NM, Hu Y, Hu X, Volchuk A, et al
    Therapeutic Targeting of High-Mobility Group Box-1 in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2019;199:1566-1569.
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  200. KOHLI P, Kelly VJ, Kehl EG, Rodriguez-Lopez J, et al
    Perfusion Imaging Distinguishes Exercise Pulmonary Arterial Hypertension at Rest.
    Am J Respir Crit Care Med. 2019;199:1438-1441.
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  201. TELLO K, Dalmer A, Husain-Syed F, Seeger W, et al
    Multibeat Right Ventricular-Arterial Coupling during a Positive Acute Vasoreactivity Test.
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  202. SAWADA H, Mitani Y, Nakayama T, Fukushima H, et al
    Detection of Pediatric Pulmonary Arterial Hypertension by School Electrocardiography Mass Screening.
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    May 2019
  203. RUIGROK D, Meijboom LJ, Westerhof BE, In 't Veld AH, et al
    Right Ventricular Load and Function in Chronic Thromboembolic Pulmonary Hypertension: Differences between Proximal and Distal Chronic Thromboembolic Pulmonary Hypertension.
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    PubMed    


    April 2019
  204. NIKOLIC I, Yung LM, Yang P, Malhotra R, et al
    Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension.
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    March 2019
  205. TANGUAY VF, Babin C, Giardetti G, Sohier-Poirier C, et al
    Enhanced Pulmonary Artery Radiodensity in Pulmonary Arterial Hypertension: A Sign of Early Calcification?
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    February 2019
  206. TRANKLE CR, Canada JM, Kadariya D, Markley R, et al
    IL-1 Blockade Reduces Inflammation in Pulmonary Arterial Hypertension and Right Ventricular Failure: A Single-Arm, Open-Label, Phase IB/II Pilot Study.
    Am J Respir Crit Care Med. 2019;199:381-384.
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    January 2019
  207. GRAHAM BB, Yu PB
    Finding the Target: In Silico and Genetic Screening for Mechanistically Novel Drugs in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2019;199:9-11.
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  208. DANNEWITZ PROSSEDA S, Tian X, Kuramoto K, Boehm M, et al
    FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension.
    Am J Respir Crit Care Med. 2019;199:83-98.
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