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  Pulmonary Hypertension

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Articles published in Circ Res

Retrieve available abstracts of 38 articles:
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Single Articles


    October 2025
  1. KIM Y, Maroli G, Woodcock CC, Kim H, et al
    Deficiency of Smooth Muscle ADAR1 Exacerbates Vascular Remodeling and Pulmonary Hypertension.
    Circ Res. 2025 Oct 22. doi: 10.1161/CIRCRESAHA.125.326235.
    PubMed     Abstract available


    May 2025
  2. MEI J, Huang W, Meng Z, Wen S, et al
    Super-Enhancer-Driven HCG20 Promotes Pulmonary Hypertension Through U2AF2 Splicing.
    Circ Res. 2025 May 28. doi: 10.1161/CIRCRESAHA.125.326133.
    PubMed     Abstract available


  3. QIU F, Miao HR, Hui HL, Qiu LJ, et al
    MHCII(hi)LYVE1(lo)CCR2(hi) Interstitial Macrophages Promote Medial Fibrosis in Pulmonary Arterioles and Contribute to Pulmonary Hypertension.
    Circ Res. 2025 May 13. doi: 10.1161/CIRCRESAHA.125.326173.
    PubMed     Abstract available


  4. ZHAKEER G, Zeng Y, E G, Maimaitiaili N, et al
    T(reg) Cells Attenuate Pulmonary Venous Remodeling in PH-LHD via NLRC3 Signaling.
    Circ Res. 2025;136:e113-e128.
    PubMed     Abstract available


    April 2025
  5. KNOEPP F, Abid S, Houssaini A, Lipskaia L, et al
    Piezo1 in PASMCs: Critical for Hypoxia-Induced Pulmonary Hypertension Development.
    Circ Res. 2025 Apr 4. doi: 10.1161/CIRCRESAHA.124.325475.
    PubMed     Abstract available


    March 2025
  6. ZHANG J, Gu X, Cheng TL, Qi YJ, et al
    ASH2L Deficiency in Smooth Muscle Drives Pulmonary Vascular Remodeling.
    Circ Res. 2025;136:719-734.
    PubMed     Abstract available


    December 2024
  7. PEI Y, Ren D, Yin Y, Shi J, et al
    Endothelial FUNDC1 Deficiency Drives Pulmonary Hypertension.
    Circ Res. 2024 Dec 10. doi: 10.1161/CIRCRESAHA.124.325156.
    PubMed     Abstract available


    October 2024
  8. KAZMIRCZAK F, Vogel NT, Prisco SZ, Patterson MT, et al
    Ferroptosis Mediated Inflammation Promotes Pulmonary Hypertension.
    Circ Res. 2024 Oct 18. doi: 10.1161/CIRCRESAHA.123.324138.
    PubMed     Abstract available


    June 2024
  9. RAFIKOVA O, James J, Kudryashova TV
    EnFUSiasm for Healing: Ultrasound Neuromodulation in PAH.
    Circ Res. 2024;135:57-59.
    PubMed    


    May 2024
  10. ICHIMURA K, Boehm M, Andruska AM, Zhang F, et al
    3D Imaging Reveals Complex Microvascular Remodeling in the Right Ventricle in Pulmonary Hypertension.
    Circ Res. 2024 May 21. doi: 10.1161/CIRCRESAHA.123.323546.
    PubMed     Abstract available


  11. LI Y, Wei X, Xiao R, Chen Y, et al
    SMYD2-Methylated PPARgamma Facilitates Hypoxia-Induced Pulmonary Hypertension by Activating Mitophagy.
    Circ Res. 2024 May 21. doi: 10.1161/CIRCRESAHA.124.323698.
    PubMed     Abstract available


  12. ZHANG J, Li Y, Chen Y, Zhang J, et al
    o(8)G Site-Specifically Modified tRF-1-AspGTC: A Novel Therapeutic Target and Biomarker for Pulmonary Hypertension.
    Circ Res. 2024 May 15. doi: 10.1161/CIRCRESAHA.124.324421.
    PubMed     Abstract available


  13. ZAFEIROPOULOS S, Ahmed U, Bekiaridou A, Jayaprakash N, et al
    Ultrasound Neuromodulation of an Anti-Inflammatory Pathway at the Spleen Improves Experimental Pulmonary Hypertension.
    Circ Res. 2024 May 7. doi: 10.1161/CIRCRESAHA.123.323679.
    PubMed     Abstract available


    April 2024
  14. CHU X, Kheirollahi V, Lingampally A, Chelladurai P, et al
    GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension.
    Circ Res. 2024 Apr 19. doi: 10.1161/CIRCRESAHA.123.323736.
    PubMed     Abstract available


    March 2024
  15. COSTE B, Delmas P
    PIEZO Ion Channels in Cardiovascular Functions and Diseases.
    Circ Res. 2024;134:572-591.
    PubMed     Abstract available


    February 2024
  16. MURUGESAN P, Zhang Y, Huang Y, Chengong Zong N, et al
    Reversal of Pulmonary Hypertension in a Human-Like Model: Therapeutic Targeting of Endothelial DHFR.
    Circ Res. 2024 Feb 1. doi: 10.1161/CIRCRESAHA.123.323090.
    PubMed     Abstract available


    December 2023
  17. KNIGHT H, Abis G, Kaur M, Green HLH, et al
    Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation.
    Circ Res. 2023;133:966-988.
    PubMed     Abstract available


    November 2023
  18. DAI Z, Thorp EB
    New Way to Study Pulmonary Hypertension in HFpEF.
    Circ Res. 2023;133:899-901.
    PubMed    


  19. AGRAWAL V, Kropski JA, Gokey JJ, Kobeck E, et al
    Myeloid Cell Derived IL1beta Contributes to Pulmonary Hypertension in HFpEF.
    Circ Res. 2023;133:885-898.
    PubMed     Abstract available


    September 2023
  20. RANASINGHE ADCU, Holohan M, Borger KM, Donahue DL, et al
    Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension.
    Circ Res. 2023 Sep 12. doi: 10.1161/CIRCRESAHA.123.322740.
    PubMed     Abstract available


    August 2023
  21. ZHOU X, Jiang Y, Wang Y, Fan L, et al
    Endothelial FIS1 DeSUMOylation Protects Against Hypoxic Pulmonary Hypertension.
    Circ Res. 2023 Aug 17. doi: 10.1161/CIRCRESAHA.122.321200.
    PubMed     Abstract available


    May 2023
  22. GONCHAROVA EA, Kudryashova TV, de Jesus Perez VA, Rafikova O, et al
    UnWNTing the Heart: Targeting WNT Signaling in Pulmonary Arterial Hypertension.
    Circ Res. 2023;132:1486-1488.
    PubMed    


  23. NAYAKANTI SR, Friedrich A, Sarode P, Jafari L, et al
    Targeting Wnt-ss-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling.
    Circ Res. 2023;132:1468-1485.
    PubMed     Abstract available


    February 2023
  24. WANG L, Moonen JR, Cao A, Isobe S, et al
    Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension.
    Circ Res. 2023 Feb 6. doi: 10.1161/CIRCRESAHA.121.320541.
    PubMed     Abstract available


  25. PI H, Xia L, Ralph DD, Rayner SG, et al
    Metabolomic Signatures Associated With Pulmonary Arterial Hypertension Outcomes.
    Circ Res. 2023;132:254-266.
    PubMed     Abstract available


    January 2023
  26. CUTHBERTSON I, Morrell NW, Caruso P
    BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension.
    Circ Res. 2023;132:109-126.
    PubMed     Abstract available


    October 2022
  27. NANDULA PS, Shah SD, Park CS, Kim SH, et al
    Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling.
    Circ Res. 2022;131:792-806.
    PubMed     Abstract available


  28. WANG C, Xing Y, Zhang J, He M, et al
    MED1 Regulates BMP/TGF-beta in Endothelium: Implication for Pulmonary Hypertension.
    Circ Res. 2022 Oct 14. doi: 10.1161/CIRCRESAHA.122.321532.
    PubMed     Abstract available


  29. KUDRYASHOVA TV, Goncharova EA
    MonOrail to Cure? Targeting Orai1 to Reverse Pulmonary Arterial Hypertension.
    Circ Res. 2022;131:728-730.
    PubMed    


  30. MASSON B, Le Ribeuz H, Sabourin J, Laubry L, et al
    Orai1 Inhibitors as Potential Treatments for Pulmonary Arterial Hypertension.
    Circ Res. 2022;131:e102-e119.
    PubMed     Abstract available


    April 2022
  31. HUSTON JH, Shah SJ
    Understanding the Pathobiology of Pulmonary Hypertension Due to Left Heart Disease.
    Circ Res. 2022;130:1382-1403.
    PubMed     Abstract available


  32. RHODES CJ, Sweatt AJ, Maron BA
    Harnessing Big Data to Advance Treatment and Understanding of Pulmonary Hypertension.
    Circ Res. 2022;130:1423-1444.
    PubMed     Abstract available


  33. SINGH N, Dorfmuller P, Shlobin OA, Ventetuolo CE, et al
    Group 3 Pulmonary Hypertension: From Bench to Bedside.
    Circ Res. 2022;130:1404-1422.
    PubMed     Abstract available


  34. BOUCHERAT O, Agrawal V, Lawrie A, Bonnet S, et al
    The Latest in Animal Models of Pulmonary Hypertension and Right Ventricular Failure.
    Circ Res. 2022;130:1466-1486.
    PubMed     Abstract available


  35. ALDRED MA, Morrell NW, Guignabert C
    New Mutations and Pathogenesis of Pulmonary Hypertension: Progress and Puzzles in Disease Pathogenesis.
    Circ Res. 2022;130:1365-1381.
    PubMed     Abstract available


  36. ALENEZI F, Covington TA, Mukherjee M, Mathai SC, et al
    Novel Approaches to Imaging the Pulmonary Vasculature and Right Heart.
    Circ Res. 2022;130:1445-1465.
    PubMed     Abstract available


    March 2022
  37. CULLEY MK, Chan SY
    Endothelial Senescence: A New Age in Pulmonary Hypertension.
    Circ Res. 2022;130:928-941.
    PubMed     Abstract available


  38. KUDRYASHOVA TV, Dabral S, Nayakanti S, Ray A, et al
    Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival.
    Circ Res. 2022;130:760-778.
    PubMed     Abstract available


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