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Pulmonary Hypertension

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January 2024
1. SAKARIN S, Rungsipipat A, Roytrakul S, Jaresitthikunchai J, et al
   Proteomic analysis of pulmonary arteries and lung tissues from dogs affected with pulmonary hypertension secondary to degenerative mitral valve disease.
   PLoS One. 2024;19:e0296068.
   PubMed     Abstract available
   
   
   
2. LIU H, Pan Z, Wu X, Gong C, et al
   Jagged 2 inhibition attenuates hypoxia-induced mitochondrial damage and pulmonary hypertension through Sirtuin 1 signaling.
   PLoS One. 2024;19:e0297525.
   PubMed     Abstract available
   
   
   
3. ZHAN S, Wang L, Wang W, Li R, et al
   Analysis of genes characterizing chronic thrombosis and associated pathways in chronic thromboembolic pulmonary hypertension.
   PLoS One. 2024;19:e0299912.
   PubMed     Abstract available
   
   
   
4. YONEDA K, Seki T, Kawazoe Y, Ohe K, et al
   Immediate postnatal prediction of death or bronchopulmonary dysplasia among very preterm and very low birth weight infants based on gradient boosting decision trees algorithm: A nationwide database study in Japan.
   PLoS One. 2024;19:e0300817.
   PubMed     Abstract available
   
   
   
5. MATSUNAGA T, Kono A, Nishio M, Yoshii T, et al
   Development and web deployment of prediction model for pulmonary arterial pressure in chronic thromboembolic pulmonary hypertension using machine learning.
   PLoS One. 2024;19:e0300716.
   PubMed     Abstract available
   
   
   January 2023
6. MCCORMACK C, Kehoe B, Cullivan S, McCaffrey N, et al
   Exploration of physical activity knowledge, preferences and support needs among pulmonary hypertension patients.
   PLoS One. 2023;18:e0277696.
   PubMed     Abstract available
   
   
   
7. TAKIGAMI M, Nakanishi N, Tsubata H, Fukai K, et al
   Efficacy and safety of guide extension catheter in balloon pulmonary angioplasty for treatment of complex lesions in chronic thromboembolic pulmonary hypertension.
   PLoS One. 2023;18:e0280683.
   PubMed     Abstract available
   
   
   
8. MURNI IK, Patmasari L, Wirawan MT, Arafuri N, et al
   Outcome and factors associated with undernutrition among children with congenital heart disease.
   PLoS One. 2023;18:e0281753.
   PubMed     Abstract available
   
   
   
9. KRONBERGER C, Mousavi RA, Ozturk B, Willixhofer R, et al
   Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST).
   PLoS One. 2023;18:e0282697.
   PubMed     Abstract available
   
   
   
10. YANG Q, Fan W, Lai B, Liao B, et al
    lncRNA-TCONS_00008552 expression in patients with pulmonary arterial hypertension due to congenital heart disease.
    PLoS One. 2023;18:e0281061.
    PubMed     Abstract available
    
    
    
11. TUKPAH AC, Rose JA, Seger DL, Dellaripa PF, et al
    Development and validation of algorithms to build an electronic health record based cohort of patients with systemic sclerosis.
    PLoS One. 2023;18:e0283775.
    PubMed     Abstract available
    
    
    
12. GODA A, Yanagisawa Y, Takeuchi S, Takeuchi K, et al
    Characteristics of cardiopulmonary exercise testing in patients with combined post- and pre-capillary pulmonary hypertension due to left heart disease.
    PLoS One. 2023;18:e0286057.
    PubMed     Abstract available
    
    
    
13. KITANO T, Nabeshima Y, Nagata Y, Takeuchi M, et al
    Prognostic value of the right ventricular ejection fraction using three-dimensional echocardiography: Systematic review and meta-analysis.
    PLoS One. 2023;18:e0287924.
    PubMed     Abstract available
    
    
    
14. TSEGA W, Awoke W, Sendekie AK, Dagnew EM, et al
    Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia.
    PLoS One. 2023;18:e0288698.
    PubMed     Abstract available
    
    
    
15. RAMBARAT P, Zern EK, Wang D, Roshandelpoor A, et al
    Identifying high risk clinical phenogroups of pulmonary hypertension through a clustering analysis.
    PLoS One. 2023;18:e0290553.
    PubMed     Abstract available
    
    
    
16. HENRY DS, Pellegrino RG
    A case-control study of phosphodiesterase-5 inhibitor use and Alzheimer's disease and related dementias among male and female patients aged 65 years and older supporting the need for a phase III clinical trial.
    PLoS One. 2023;18:e0292863.
    PubMed     Abstract available
    
    
    January 2022
17. TAKIGAMI M, Tsubata H, Nakanishi N, Matsubara Y, et al
    The effectiveness of scoring balloon angioplasty in the treatment of chronic thromboembolic pulmonary hypertension.
    PLoS One. 2022;17:e0263244.
    PubMed     Abstract available
    
    
    
18. BOLOURANI S, Sari E, Brenner M, Wang P, et al
    The role of eCIRP in bleomycin-induced pulmonary fibrosis in mice.
    PLoS One. 2022;17:e0266163.
    PubMed     Abstract available
    
    
    
19. HAYASHI R, Kogiso T, Kikuchi N, Yamamoto K, et al
    Portopulmonary hypertension and the risk of high right ventricular systolic pressure in liver transplant candidates.
    PLoS One. 2022;17:e0267125.
    PubMed     Abstract available
    
    
    
20. VICENZI M, Caravita S, Rota I, Casella R, et al
    The added value of right ventricular function normalized for afterload to improve risk stratification of patients with pulmonary arterial hypertension.
    PLoS One. 2022;17:e0265059.
    PubMed     Abstract available
    
    
    
21. REZENDE CF, Mancuzo EV, Correa RA
    Heart rate recovery in 1 minute after the 6-minute walk test predicts adverse outcomes in pulmonary arterial hypertension.
    PLoS One. 2022;17:e0268839.
    PubMed     Abstract available
    
    
    
22. TSEGA T, Tesfaye T, Dessie A, Teshome T, et al
    Nutritional assessment and associated factors in children with congenital heart disease-Ethiopia.
    PLoS One. 2022;17:e0269518.
    PubMed     Abstract available
    
    
    
23. CARDOSO NL, de Sa JF, do Nascimento LFE, Mendes LA, et al
    Psychometric properties of the sit-to-stand test for patients with pulmonary hypertension: A systematic review protocol.
    PLoS One. 2022;17:e0275646.
    PubMed     Abstract available
    
    
    
24. JASINSKA-STROSCHEIN M
    Training programs in preclinical studies. The example of pulmonary hypertension. Systematic review and meta-analysis.
    PLoS One. 2022;17:e0276875.
    PubMed     Abstract available
    
    
    
25. RAMSEY SD, Bender MA, Li L, Johnson KM, et al
    Prevalence of comorbidities associated with sickle cell disease among non-elderly individuals with commercial insurance-A retrospective cohort study.
    PLoS One. 2022;17:e0278137.
    PubMed     Abstract available
    
    
    January 2021
26. FINGROVA Z, Ambroz D, Jansa P, Kuchar J, et al
    The prevalence and clinical outcome of supraventricular tachycardia in different etiologies of pulmonary hypertension.
    PLoS One. 2021;16:e0245752.
    PubMed     Abstract available
    
    
    
27. RAJARATNAM A, Rehman S, Sharma P, Singh VK, et al
    Right ventricular load and contractility in HIV-associated pulmonary hypertension.
    PLoS One. 2021;16:e0243274.
    PubMed     Abstract available
    
    
    
28. IBE T, Wada H, Sakakura K, Ugata Y, et al
    Combined pre- and post-capillary pulmonary hypertension: The clinical implications for patients with heart failure.
    PLoS One. 2021;16:e0247987.
    PubMed     Abstract available
    
    
    
29. HONIGBERG MC, Patel AP, Lahm T, Wood MJ, et al
    Association of premature menopause with incident pulmonary hypertension: A cohort study.
    PLoS One. 2021;16:e0247398.
    PubMed     Abstract available
    
    
    
30. TAWA M, Nagata R, Sumi Y, Nakagawa K, et al
    Preventive effects of nitrate-rich beetroot juice supplementation on monocrotaline-induced pulmonary hypertension in rats.
    PLoS One. 2021;16:e0249816.
    PubMed     Abstract available
    
    
    
31. MOHER ALSADY T, Kaireit TF, Behrendt L, Winther HB, et al
    Comparison of dual-energy computer tomography and dynamic contrast-enhanced MRI for evaluating lung perfusion defects in chronic thromboembolic pulmonary hypertension.
    PLoS One. 2021;16:e0251740.
    PubMed     Abstract available
    
    
    
32. FUJII S, Nagayoshi S, Ogawa K, Muto M, et al
    A pilot cohort study assessing the feasibility of complete revascularization with balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension.
    PLoS One. 2021;16:e0254770.
    PubMed     Abstract available
    
    
    
33. MIURA K, Katsumata Y, Kawakami T, Ikura H, et al
    Exercise tolerance and quality of life in hemodynamically partially improved patients with chronic thromboembolic pulmonary hypertension treated with balloon pulmonary angioplasty.
    PLoS One. 2021;16:e0255180.
    PubMed     Abstract available
    
    
    
34. RIENGVIRODKIJ N, Roytrakul S, Jaresitthikunchai J, Phaonakrop N, et al
    Peptide barcodes in dogs affected by mitral valve disease with and without pulmonary hypertension using MALDI-TOF MS and LC-MS/MS.
    PLoS One. 2021;16:e0255611.
    PubMed     Abstract available
    
    
    
35. BUTT S, Jeppesen JL, Iversen LV, Fenger M, et al
    Association of soluble urokinase plasminogen activator receptor levels with fibrotic and vascular manifestations in systemic sclerosis.
    PLoS One. 2021;16:e0247256.
    PubMed     Abstract available
    
    
    
36. WAKABAYASHI SI, Joshita S, Kimura K, Motoki H, et al
    Protocol: Prospective observational study investigating the prevalence and clinical outcome of portopulmonary hypertension in Japanese patients with chronic liver disease.
    PLoS One. 2021;16:e0249435.
    PubMed     Abstract available
    
    
    
37. HOVNANIAN ALD, Costa ELV, Hoette S, Fernandes CJCS, et al
    Electrical impedance tomography in pulmonary arterial hypertension.
    PLoS One. 2021;16:e0248214.
    PubMed     Abstract available
    
    
    
38. AMODEO I, De Nunzio G, Raffaeli G, Borzani I, et al
    A maChine and deep Learning Approach to predict pulmoNary hyperteNsIon in newbornS with congenital diaphragmatic Hernia (CLANNISH): Protocol for a retrospective study.
    PLoS One. 2021;16:e0259724.
    PubMed     Abstract available
    
    
    
39. MARIANO TB, de Souza Castilho AC, de Almeida Sabela AKD, de Oliveira AC, et al
    Preventive training does not interfere with mRNA-encoding myosin and collagen expression during pulmonary arterial hypertension.
    PLoS One. 2021;16:e0244768.
    PubMed     Abstract available
    
    
    
40. JOKI Y, Konishi H, Ebinuma H, Takasu K, et al
    Circulating sLR11 levels predict severity of pulmonary hypertension due to left heart disease.
    PLoS One. 2021;16:e0261753.
    PubMed     Abstract available
    
    
    
41. ASANO R, Ogo T, Morita Y, Kotoku A, et al
    Prognostic value of right ventricular native T1 mapping in pulmonary arterial hypertension.
    PLoS One. 2021;16:e0260456.
    PubMed     Abstract available
    
    
    January 2020
42. RINASTITI P, Ikeda K, Rahardini EP, Miyagawa K, et al
    Loss of family with sequence similarity 13, member A exacerbates pulmonary hypertension through accelerating endothelial-to-mesenchymal transition.
    PLoS One. 2020;15:e0226049.
    PubMed     Abstract available
    
    
    
43. ZOUK AN, Gulati S, Xing D, Wille KM, et al
    Pulmonary artery enlargement is associated with pulmonary hypertension and decreased survival in severe cystic fibrosis: A cohort study.
    PLoS One. 2020;15:e0229173.
    PubMed     Abstract available
    
    
    
44. SARA JDS, Maor E, Borlaug B, Lewis BR, et al
    Non-invasive vocal biomarker is associated with pulmonary hypertension.
    PLoS One. 2020;15:e0231441.
    PubMed     Abstract available
    
    
    
45. CONNOLLY M, Garfield BE, Crosby A, Morrell NW, et al
    miR-1-5p targets TGF-betaR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.
    PLoS One. 2020;15:e0229409.
    PubMed     Abstract available
    
    
    
46. KAISER R, Liu D, Arias-Loza P, Hu K, et al
    Right ventricular pressure overload directly affects left ventricular torsion mechanics in patients with precapillary pulmonary hypertension.
    PLoS One. 2020;15:e0232544.
    PubMed     Abstract available
    
    
    
47. CASTRO MA, Piloto B, Dos Santos Fernandes CJC, Jardim C, et al
    Use of medical therapies before pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension patients with severe hemodynamic impairment.
    PLoS One. 2020;15:e0233063.
    PubMed     Abstract available
    
    
    
48. SCHNEIDER M, Ran H, Pistritto AM, Gerges C, et al
    Pulmonary artery to ascending aorta ratio by echocardiography: A strong predictor for presence and severity of pulmonary hypertension.
    PLoS One. 2020;15:e0235716.
    PubMed     Abstract available
    
    
    
49. NAKATSUKA Y, Chen-Yoshikawa T, Kinoshita H, Aoyama A, et al
    Nocturnal hypercapnia with daytime normocapnia in patients with advanced pulmonary arterial hypertension awaiting lung transplantation.
    PLoS One. 2020;15:e0227775.
    PubMed     Abstract available
    
    
    
50. HILDE JM, Hisdal J, Skjorten I, Hansteen V, et al
    Left ventricular dysfunction in COPD without pulmonary hypertension.
    PLoS One. 2020;15:e0235075.
    PubMed     Abstract available
    
    
    
51. ZOU XL, Ren Y, Feng DY, He XQ, et al
    A promising approach for screening pulmonary hypertension based on frontal chest radiographs using deep learning: A retrospective study.
    PLoS One. 2020;15:e0236378.
    PubMed     Abstract available
    
    
    
52. HERNANDEZ-GONZALEZ I, Tenorio J, Palomino-Doza J, Martinez Menaca A, et al
    Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.
    PLoS One. 2020;15:e0232216.
    PubMed     Abstract available
    
    
    
53. BOON GJAM, Rein NV, Bogaard HJ, Ende-Verhaar YM, et al
    Quality of initial anticoagulant treatment and risk of CTEPH after acute pulmonary embolism.
    PLoS One. 2020;15:e0232354.
    PubMed     Abstract available
    
    
    
54. RIEG AD, Suleiman S, Bunting NA, Verjans E, et al
    Levosimendan reduces segmental pulmonary vascular resistance in isolated perfused rat lungs and relaxes human pulmonary vessels.
    PLoS One. 2020;15:e0233176.
    PubMed     Abstract available
    
    
    
55. ZHANG H, Huang W, Liu H, Zheng Y, et al
    Mechanical stretching of pulmonary vein stimulates matrix metalloproteinase-9 and transforming growth factor-beta1 through stretch-activated channel/MAPK pathways in pulmonary hypertension due to left heart disease model rats.
    PLoS One. 2020;15:e0235824.
    PubMed     Abstract available
    
    
    
56. SASAKI K, Yamamoto S, Mutoh T
    Noninvasive assessment of fluid responsiveness for emergency abdominal surgery in dogs with pulmonary hypertension: Insights into high-risk companion animal anesthesia.
    PLoS One. 2020;15:e0241234.
    PubMed     Abstract available
    
    
    
57. JANG AY, Kim BG, Kwon S, Seo J, et al
    Prevalence and clinical features of bone morphogenetic protein receptor type 2 mutation in Korean idiopathic pulmonary arterial hypertension patients: The PILGRIM explorative cohort.
    PLoS One. 2020;15:e0238698.
    PubMed     Abstract available
    
    
    
58. CZERNER CP, Schoenfeld C, Cebotari S, Renne J, et al
    Perioperative CTEPH patient monitoring with 2D phase-contrast MRI reflects clinical, cardiac and pulmonary perfusion changes after pulmonary endarterectomy.
    PLoS One. 2020;15:e0238171.
    PubMed     Abstract available
    
    
    
59. VALENTE C, Guglielmini C, Domenech O, Contiero B, et al
    Symmetric dimethylarginine in dogs with myxomatous mitral valve disease at various stages of disease severity.
    PLoS One. 2020;15:e0238440.
    PubMed     Abstract available
    
    
    
60. SALIBE-FILHO W, Araujo TLS, G Melo E, B C T Coimbra L, et al
    Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension.
    PLoS One. 2020;15:e0242960.
    PubMed     Abstract available
    
    
    
61. CASTELLVI I, Simeon CP, Sarmiento M, Casademont J, et al
    Effect of bosentan in pulmonary hypertension development in systemic sclerosis patients with digital ulcers.
    PLoS One. 2020;15:e0243651.
    PubMed     Abstract available
    
    
    
62. MOHAMMAD AM, Dawad MM, Kashmoola MA, Al-Allawi N, et al
    Doppler-defined pulmonary hypertension in beta-thalassemia major in Kurdistan, Iraq.
    PLoS One. 2020;15:e0243648.
    PubMed     Abstract available
    
    
    
63. HONDA Y, Kosugi K, Fuchikami C, Kuramoto K, et al
    The selective PGI2 receptor agonist selexipag ameliorates Sugen 5416/hypoxia-induced pulmonary arterial hypertension in rats.
    PLoS One. 2020;15:e0240692.
    PubMed     Abstract available
    
    
    
64. SAHAY S, Tonelli AR, Selej M, Watson Z, et al
    Risk assessment in patients with functional class II pulmonary arterial hypertension: Comparison of physician gestalt with ESC/ERS and the REVEAL 2.0 risk score.
    PLoS One. 2020;15:e0241504.
    PubMed     Abstract available
    
    
    January 2019
65. SIEREN MM, Berlin C, Oechtering TH, Hunold P, et al
    Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension.
    PLoS One. 2019;14:e0224121.
    PubMed     Abstract available
    
    
    
66. LEHA A, Hellenkamp K, Unsold B, Mushemi-Blake S, et al
    A machine learning approach for the prediction of pulmonary hypertension.
    PLoS One. 2019;14:e0224453.
    PubMed     Abstract available
    
    
    
67. WERTHEIM BM, Lin YD, Zhang YY, Samokhin AO, et al
    Isolating pulmonary microvascular endothelial cells ex vivo: Implications for pulmonary arterial hypertension, and a caution on the use of commercial biomaterials.
    PLoS One. 2019;14:e0211909.
    PubMed     Abstract available
    
    
    
68. CHIDA-NAGAI A, Shintani M, Sato H, Nakayama T, et al
    Role of BRCA1-associated protein (BRAP) variant in childhood pulmonary arterial hypertension.
    PLoS One. 2019;14:e0211450.
    PubMed     Abstract available
    
    
    
69. AL-ZAHRANI K, Licknack T, Watson DL, Anthony NB, et al
    Further investigation of mitochondrial biogenesis and gene expression of key regulators in ascites- susceptible and ascites- resistant broiler research lines.
    PLoS One. 2019;14:e0205480.
    PubMed     Abstract available
    
    
    
70. WAKASUGI T, Shimizu I, Yoshida Y, Hayashi Y, et al
    Role of smooth muscle cell p53 in pulmonary arterial hypertension.
    PLoS One. 2019;14:e0212889.
    PubMed     Abstract available
    
    
    
71. HAYABUCHI Y, Homma Y, Kagami S
    Optical coherence tomography for observing development of pulmonary arterial vasa vasorum after bidirectional cavopulmonary connection in children.
    PLoS One. 2019;14:e0215146.
    PubMed     Abstract available
    
    
    
72. CHUNCHARUNEE S, Teawtrakul N, Siritanaratkul N, Chueamuangphan N, et al
    Review of disease-related complications and management in adult patients with thalassemia: A multi-center study in Thailand.
    PLoS One. 2019;14:e0214148.
    PubMed     Abstract available
    
    
    
73. BHAGWANI AR, Hultman S, Farkas D, Moncayo R, et al
    Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension.
    PLoS One. 2019;14:e0213890.
    PubMed     Abstract available
    
    
    
74. SHAH NB, Mitchell RE, Proctor ST, Choi L, et al
    High rates of medication adherence in patients with pulmonary arterial hypertension: An integrated specialty pharmacy approach.
    PLoS One. 2019;14:e0217798.
    PubMed     Abstract available
    
    
    
75. TSUTSUMI T, Nagaoka T, Yoshida T, Wang L, et al
    Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation.
    PLoS One. 2019;14:e0214697.
    PubMed     Abstract available
    
    
    
76. WILSON JL, Wang L, Zhang Z, Hill NS, et al
    Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension.
    PLoS One. 2019;14:e0221728.
    PubMed     Abstract available
    
    
    
77. SEKI M, Furukawa N, Koitabashi N, Obokata M, et al
    Periostin-expressing cell-specific transforming growth factor-beta inhibition in pulmonary artery prevents pulmonary arterial hypertension.
    PLoS One. 2019;14:e0220795.
    PubMed     Abstract available
    
    
    
78. BRUNS DR, Tatman PD, Kalkur RS, Brown RD, et al
    The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation.
    PLoS One. 2019;14:e0220573.
    PubMed     Abstract available
    
    
    
79. NGUYEN QL, Wang Y, Helbling N, Simon MA, et al
    Alterations in platelet bioenergetics in Group 2 PH-HFpEF patients.
    PLoS One. 2019;14:e0220490.
    PubMed     Abstract available
    
    
    
80. BERGOT E, De Leotoing L, Bendjenana H, Tournier C, et al
    Hospital burden of pulmonary arterial hypertension in France.
    PLoS One. 2019;14:e0221211.
    PubMed     Abstract available
    
    
    
81. ABSI M, Eid BG, Ashton N, Hart G, et al
    Simvastatin causes pulmonary artery relaxation by blocking smooth muscle ROCK and calcium channels: Evidence for an endothelium-independent mechanism.
    PLoS One. 2019;14:e0220473.
    PubMed     Abstract available
    
    
    
82. CHAU Y, Li FS, Levsh O, Weng JK, et al
    Exploration of icariin analog structure space reveals key features driving potent inhibition of human phosphodiesterase-5.
    PLoS One. 2019;14:e0222803.
    PubMed     Abstract available
    
    
    
83. AXELSEN JB, Andersen S, Sun XQ, Ringgaard S, et al
    Effects of 6-mercaptopurine in pressure overload induced right heart failure.
    PLoS One. 2019;14:e0225122.
    PubMed     Abstract available
    
    

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