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Articles published in Toxicol Sci

Retrieve available abstracts of 24 articles:
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Single Articles


    August 2022
  1. CHEN Y, Song W, Ge W, Yan R, et al
    Metabolic competency of larval zebrafish in drug-induced liver injury: a case study of acetaminophen poisoning.
    Toxicol Sci. 2022 Aug 9. pii: 6659117. doi: 10.1093.
    PubMed     Abstract available


    July 2022
  2. NGUYEN NT, Umbaugh DS, Huang EL, Adelusi OB, et al
    Recovered Hepatocytes Promote Macrophage Apoptosis Through CXCR4 After Acetaminophen-Induced Liver Injury in Mice.
    Toxicol Sci. 2022;188:248-260.
    PubMed     Abstract available


  3. MARTIN MT, Koza-Taylor P, Di L, Watt ED, et al
    Early Drug-Induced Liver Injury Risk Screening: "Free," as Good as It Gets.
    Toxicol Sci. 2022;188:208-218.
    PubMed     Abstract available


    June 2022
  4. WOODHEAD JL, Siler SQ, Howell BA, Watkins PB, et al
    Comparing the Liver Safety Profiles of 4 Next-Generation CGRP Receptor Antagonists to the Hepatotoxic CGRP Inhibitor Telcagepant Using Quantitative Systems Toxicology Modeling.
    Toxicol Sci. 2022;188:108-116.
    PubMed     Abstract available


    April 2022
  5. CARSTENS KE, Carpenter AF, Martin MM, Harrill JA, et al
    Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity.
    Toxicol Sci. 2022;187:62-79.
    PubMed     Abstract available


    February 2022
  6. MARABLE CA, Frank CL, Seim RF, Hester S, et al
    Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated With Chemical Alterations of In Vitro Neural Network Formation.
    Toxicol Sci. 2022;186:118-133.
    PubMed     Abstract available


    January 2022
  7. MORRIS J, Bealer EJ, Souza IDS, Repmann L, et al
    Chemical Exposure-Induced Developmental Neurotoxicity in Head-Regenerating Schmidtea mediterranea.
    Toxicol Sci. 2022;185:220-231.
    PubMed     Abstract available


  8. SHERLOCK LG, Balasubramaniyan D, Zheng L, Grayck M, et al
    APAP-Induced IkappaBbeta/NFkappaB Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation.
    Toxicol Sci. 2022;185:158-169.
    PubMed     Abstract available


    December 2021
  9. CHEN S, Tang Y, Fang W, He T, et al
    CoQ10 Promotes Resolution of Necrosis and Liver Regeneration After Acetaminophen-Induced Liver Injury.
    Toxicol Sci. 2021;185:19-27.
    PubMed     Abstract available


    November 2021
  10. POUDEL S, Cabrera DP, Bhushan B, Manley MW, et al
    Hepatocyte-Specific Deletion of Yes-Associated Protein Improves Recovery From Acetaminophen-Induced Acute Liver Injury.
    Toxicol Sci. 2021;184:276-285.
    PubMed     Abstract available


    September 2021
  11. ANDERSON FL, von Herrmann KM, Young AL, Havrda MC, et al
    Bbc3 Loss Enhances Survival and Protein Clearance in Neurons Exposed to the Organophosphate Pesticide Chlorpyrifos.
    Toxicol Sci. 2021;183:378-392.
    PubMed     Abstract available


    August 2021
  12. HUTIN D, Long AS, Sugamori K, Shao P, et al
    2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Inducible Poly-ADP-Ribose Polymerase (TIPARP/PARP7) Catalytic Mutant Mice (TiparpH532A) Exhibit Increased Sensitivity to TCDD-Induced Hepatotoxicity and Lethality.
    Toxicol Sci. 2021;183:154-169.
    PubMed     Abstract available


  13. KRALJ T, Brouwer KLR, Creek DJ
    Analytical and Omics-Based Advances in the Study of Drug-Induced Liver Injury.
    Toxicol Sci. 2021;183:1-13.
    PubMed     Abstract available


    May 2021
  14. BELAIR DG, Sudak K, Connelly K, Collins ND, et al
    Investigation Into the Role of ERK in Tyrosine Kinase Inhibitor-Induced Neuropathy.
    Toxicol Sci. 2021;181:160-174.
    PubMed     Abstract available


  15. YAN T, Yan N, Wang H, Yagai T, et al
    FXR-Deoxycholic Acid-TNF-alpha Axis Modulates Acetaminophen-Induced Hepatotoxicity.
    Toxicol Sci. 2021;181:273-284.
    PubMed     Abstract available


  16. UMBAUGH DS, Ramachandran A, Jaeschke H
    Spatial Reconstruction of the Early Hepatic Transcriptomic Landscape after an Acetaminophen Overdose using Single-cell RNA Sequencing.
    Toxicol Sci. 2021 May 12. pii: 6275242. doi: 10.1093.
    PubMed     Abstract available


    April 2021
  17. SHEHU AI, Zhu J, Li J, Lu J, et al
    Targeting Xenobiotic Nuclear Receptors PXR and CAR to Prevent Cobicistat Hepatotoxicity.
    Toxicol Sci. 2021;181:58-67.
    PubMed     Abstract available


  18. LLEWELLYN HP, Vaidya VS, Wang Z, Peng Q, et al
    Evaluating the Sensitivity and Specificity of Promising Circulating Biomarkers to Diagnose Liver Injury in Humans.
    Toxicol Sci. 2021;181:23-34.
    PubMed     Abstract available


    February 2021
  19. UMBAUGH DS, Nguyen NT, Jaeschke H, Ramachandran A, et al
    Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure.
    Toxicol Sci. 2021;180:186-195.
    PubMed     Abstract available


    January 2021
  20. LI D, Knox B, Gong B, Chen S, et al
    Identification of Translational microRNA Biomarker Candidates for Ketoconazole-Induced Liver Injury Using Next-Generation Sequencing.
    Toxicol Sci. 2021;179:31-43.
    PubMed     Abstract available


  21. HAMMOND S, Gibson A, Jaruthamsophon K, Roth S, et al
    Shedding Light on Drug-Induced Liver Injury: Activation of T Cells From Drug Naive Human Donors With Tolvaptan and a Hydroxybutyric Acid Metabolite.
    Toxicol Sci. 2021;179:95-107.
    PubMed     Abstract available


    February 2020
  22. KOHARA H, Bajaj P, Yamanaka K, Miyawaki A, et al
    High-Throughput Screening to Evaluate Inhibition of Bile Acid Transporters Using Human Hepatocytes Isolated From Chimeric Mice.
    Toxicol Sci. 2020;173:347-361.
    PubMed     Abstract available


  23. VAZQUEZ JH, Clemens MM, Allard FD, Yee EU, et al
    Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations.
    Toxicol Sci. 2020;173:244-254.
    PubMed     Abstract available


  24. LOPEZ-RIERA M, Conde I, Castell JV, Jover R, et al
    A Novel MicroRNA Signature for Cholestatic Drugs in Human Hepatocytes and Its Translation into Novel Circulating Biomarkers for Drug-Induced Liver Injury Patients.
    Toxicol Sci. 2020;173:229-243.
    PubMed     Abstract available


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