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Articles published in Proc Natl Acad Sci U S A

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    March 2021
  1. XU L, Yin Y, Li Y, Chen X, et al
    A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2020
  2. VELLKY JE, McSweeney ST, Ricke EA, Ricke WA, et al
    RNA-binding protein DDX3 mediates posttranscriptional regulation of androgen receptor: A mechanism of castration resistance.
    Proc Natl Acad Sci U S A. 2020;117:28092-28101.
    PubMed     Abstract available


    October 2020
  3. CHAURASIYA S, Wu W, Strom AM, Warner M, et al
    Estrogen receptor beta regulates AKT activity through up-regulation of INPP4B and inhibits migration of prostate cancer cell line PC-3.
    Proc Natl Acad Sci U S A. 2020 Oct 5. pii: 2007160117.
    PubMed     Abstract available


    July 2020

  4. Correction to Supporting Information for Zadra et al., Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer.
    Proc Natl Acad Sci U S A. 2020 Jul 27. pii: 2012767117.
    PubMed    


    June 2020
  5. BICAK M, Luckerath K, Kalidindi T, Phelps ME, et al
    Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted alpha-particle therapy.
    Proc Natl Acad Sci U S A. 2020 Jun 12. pii: 1918744117.
    PubMed     Abstract available


  6. ALUMKAL JJ, Sun D, Lu E, Beer TM, et al
    Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance.
    Proc Natl Acad Sci U S A. 2020;117:12315-12323.
    PubMed     Abstract available


    May 2020
  7. LU WC, Saha A, Yan W, Garrison K, et al
    Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity.
    Proc Natl Acad Sci U S A. 2020 May 20. pii: 1917362117.
    PubMed     Abstract available


    April 2020
  8. HALDAR S, Mishra R, Billet S, Thiruvalluvan M, et al
    Cancer epithelia-derived mitochondrial DNA is a targetable initiator of a paracrine signaling loop that confers taxane resistance.
    Proc Natl Acad Sci U S A. 2020;117:8515-8523.
    PubMed     Abstract available


  9. WASMUTH EV, Hoover EA, Antar A, Klinge S, et al
    Modulation of androgen receptor DNA binding activity through direct interaction with the ETS transcription factor ERG.
    Proc Natl Acad Sci U S A. 2020;117:8584-8592.
    PubMed     Abstract available


    March 2020
  10. PHILLIPS JW, Pan Y, Tsai BL, Xie Z, et al
    Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers.
    Proc Natl Acad Sci U S A. 2020;117:5269-5279.
    PubMed     Abstract available


    February 2020
  11. PIETRZAK K, Kuzyakiv R, Simon R, Bolis M, et al
    TIP5 primes prostate luminal cells for the oncogenic transformation mediated by PTEN-loss.
    Proc Natl Acad Sci U S A. 2020;117:3637-3647.
    PubMed     Abstract available


    January 2020
  12. HSU EC, Rice MA, Bermudez A, Marques FJG, et al
    Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1.
    Proc Natl Acad Sci U S A. 2020 Jan 13. pii: 1905384117.
    PubMed     Abstract available


    October 2019
  13. MOPARTHI L, Pizzolato G, Koch S
    Wnt activator FOXB2 drives the neuroendocrine differentiation of prostate cancer.
    Proc Natl Acad Sci U S A. 2019 Oct 14. pii: 1906484116.
    PubMed     Abstract available


    July 2019
  14. JAILKHANI N, Ingram JR, Rashidian M, Rickelt S, et al
    Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix.
    Proc Natl Acad Sci U S A. 2019;116:14181-14190.
    PubMed     Abstract available


  15. GUI B, Gui F, Takai T, Feng C, et al
    Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function.
    Proc Natl Acad Sci U S A. 2019 Jul 2. pii: 1908547116.
    PubMed     Abstract available


    June 2019

  16. Correction for Geng et al., Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover.
    Proc Natl Acad Sci U S A. 2019 Jun 24. pii: 1908767116.
    PubMed    



  17. Correction for Lorenzo et al., Computer simulations suggest that prostate enlargement due to benign prostatic hyperplasia mechanically impedes prostate cancer growth.
    Proc Natl Acad Sci U S A. 2019 Jun 10. pii: 1908514116.
    PubMed    


    May 2019
  18. MA X, Huang J
    Predicting clinical outcome of therapy-resistant prostate cancer.
    Proc Natl Acad Sci U S A. 2019 May 21. pii: 1906812116.
    PubMed    


  19. STOPSACK KH, Whittaker CA, Gerke TA, Loda M, et al
    Aneuploidy drives lethal progression in prostate cancer.
    Proc Natl Acad Sci U S A. 2019 May 13. pii: 1902645116.
    PubMed     Abstract available


  20. ABIDA W, Cyrta J, Heller G, Prandi D, et al
    Genomic correlates of clinical outcome in advanced prostate cancer.
    Proc Natl Acad Sci U S A. 2019 May 6. pii: 1902651116.
    PubMed     Abstract available


    March 2019
  21. ZHENG Y, Comaills V, Burr R, Boulay G, et al
    COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis.
    Proc Natl Acad Sci U S A. 2019;116:5223-5232.
    PubMed     Abstract available


  22. PRADHAN AK, Bhoopathi P, Talukdar S, Scheunemann D, et al
    MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.
    Proc Natl Acad Sci U S A. 2019;116:5687-5692.
    PubMed     Abstract available


    January 2019
  23. LORENZO G, Hughes TJR, Dominguez-Frojan P, Reali A, et al
    Computer simulations suggest that prostate enlargement due to benign prostatic hyperplasia mechanically impedes prostate cancer growth.
    Proc Natl Acad Sci U S A. 2019 Jan 7. pii: 1815735116.
    PubMed     Abstract available


    December 2018
  24. ZADRA G, Ribeiro CF, Chetta P, Ho Y, et al
    Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer.
    Proc Natl Acad Sci U S A. 2018 Dec 21. pii: 1808834116.
    PubMed     Abstract available


    November 2018
  25. FONG LY, Jing R, Smalley KJ, Wang ZX, et al
    Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats.
    Proc Natl Acad Sci U S A. 2018;115:E11091-E11100.
    PubMed     Abstract available


    October 2018
  26. GARRIGUE P, Tang J, Ding L, Bouhlel A, et al
    Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors.
    Proc Natl Acad Sci U S A. 2018 Oct 22. pii: 1812938115.
    PubMed     Abstract available


  27. ARORA H, Panara K, Kuchakulla M, Kulandavelu S, et al
    Alterations of tumor microenvironment by nitric oxide impedes castration-resistant prostate cancer growth.
    Proc Natl Acad Sci U S A. 2018 Oct 15. pii: 1812704115.
    PubMed     Abstract available


  28. FENG S, Cheng X, Zhang L, Lu X, et al
    Myeloid-derived suppressor cells inhibit T cell activation through nitrating LCK in mouse cancers.
    Proc Natl Acad Sci U S A. 2018;115:10094-10099.
    PubMed     Abstract available


    September 2018

  29. Correction for Chen et al., Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13.
    Proc Natl Acad Sci U S A. 2018;115:E9025.
    PubMed    


    August 2018
  30. DUDANI JS, Ibrahim M, Kirkpatrick J, Warren AD, et al
    Classification of prostate cancer using a protease activity nanosensor library.
    Proc Natl Acad Sci U S A. 2018 Aug 20. pii: 1805337115.
    PubMed     Abstract available


    June 2018
  31. NAVARRO HI, Goldstein AS
    HoxB13 mediates AR-V7 activity in prostate cancer.
    Proc Natl Acad Sci U S A. 2018 Jun 11. pii: 1808196115.
    PubMed    


    May 2018
  32. CHEN Z, Wu D, Thomas-Ahner JM, Lu C, et al
    Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13.
    Proc Natl Acad Sci U S A. 2018 May 29. pii: 1718811115.
    PubMed     Abstract available


    April 2018
  33. FAN L, Zhang F, Xu S, Cui X, et al
    Histone demethylase JMJD1A promotes alternative splicing of AR variant 7 (AR-V7) in prostate cancer cells.
    Proc Natl Acad Sci U S A. 2018 Apr 30. pii: 1802415115.
    PubMed     Abstract available


  34. TAKAYAMA KI, Suzuki T, Fujimura T, Takahashi S, et al
    COBLL1 modulates cell morphology and facilitates androgen receptor genomic binding in advanced prostate cancer.
    Proc Natl Acad Sci U S A. 2018 Apr 23. pii: 1721957115.
    PubMed     Abstract available


  35. LEE JK, Bangayan NJ, Chai T, Smith BA, et al
    Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer.
    Proc Natl Acad Sci U S A. 2018 Apr 23. pii: 1802354115.
    PubMed     Abstract available


  36. ELLIS L, Loda M
    LSD1: A single target to combat lineage plasticity in lethal prostate cancer.
    Proc Natl Acad Sci U S A. 2018 Apr 16. pii: 1804205115.
    PubMed    


  37. POWELL GRAY B, Kelly L, Ahrens DP, Barry AP, et al
    Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate cancer.
    Proc Natl Acad Sci U S A. 2018 Apr 16. pii: 1717705115.
    PubMed     Abstract available


    March 2018
  38. SEHRAWAT A, Gao L, Wang Y, Bankhead A 3rd, et al
    LSD1 activates a lethal prostate cancer gene network independently of its demethylase function.
    Proc Natl Acad Sci U S A. 2018 Mar 26. pii: 1719168115.
    PubMed     Abstract available


    February 2018
  39. HASHIMOTO K, Ochi H, Sunamura S, Kosaka N, et al
    Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.
    Proc Natl Acad Sci U S A. 2018;115:2204-2209.
    PubMed     Abstract available


    October 2017
  40. KUNDU M, Roy A, Pahan K
    Selective neutralization of IL-12 p40 monomer induces death in prostate cancer cells via IL-12-IFN-gamma.
    Proc Natl Acad Sci U S A. 2017;114:11482-11487.
    PubMed     Abstract available


    September 2017
  41. TAKAYAMA KI, Suzuki T, Fujimura T, Yamada Y, et al
    Dysregulation of spliceosome gene expression in advanced prostate cancer by RNA-binding protein PSF.
    Proc Natl Acad Sci U S A. 2017 Sep 11. pii: 201706076.
    PubMed     Abstract available


    June 2017
  42. FEI T, Chen Y, Xiao T, Li W, et al
    Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.
    Proc Natl Acad Sci U S A. 2017 Jun 13. pii: 201617467.
    PubMed     Abstract available


    May 2017

  43. Correction for Dash et al., Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
    Proc Natl Acad Sci U S A. 2017 May 22. pii: 201706353.
    PubMed    


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