Home The Word Brain My Amedeo FAQ Privacy About Flying Publisher   


The Angels Initiative

Stroke prevention


  Stem Cell Research

  Free Subscription


Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 164 articles:
HTML format



Single Articles


    August 2022
  1. ARNOVITZ S, Mathur P, Tracy M, Mohsin A, et al
    Tcf-1 promotes genomic instability and T cell transformation in response to aberrant beta-catenin activation.
    Proc Natl Acad Sci U S A. 2022;119:e2201493119.
    PubMed     Abstract available


  2. LANG E, Pedersen C, Lang A, Blicher P, et al
    Mechanical coupling of supracellular stress amplification and tissue fluidization during exit from quiescence.
    Proc Natl Acad Sci U S A. 2022;119:e2201328119.
    PubMed     Abstract available


    July 2022
  3. COELHO DR, Palma FR, Paviani V, He C, et al
    Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
    Proc Natl Acad Sci U S A. 2022;119:e2110348119.
    PubMed     Abstract available


  4. KASTAN NR, Oak S, Liang R, Baxt L, et al
    Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs.
    Proc Natl Acad Sci U S A. 2022;119:e2206113119.
    PubMed     Abstract available


  5. OLIVEROS A, Yoo KH, Rashid MA, Corujo-Ramirez A, et al
    Adenosine A2A receptor blockade prevents cisplatin-induced impairments in neurogenesis and cognitive function.
    Proc Natl Acad Sci U S A. 2022;119:e2206415119.
    PubMed     Abstract available


    June 2022
  6. XU J, Liu Y, Li H, Tarashansky AJ, et al
    Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing.
    Proc Natl Acad Sci U S A. 2022;119:e2203179119.
    PubMed     Abstract available


  7. LI W, Zhu Z, He K, Ma X, et al
    Primary cilia in satellite cells are the mechanical sensors for muscle hypertrophy.
    Proc Natl Acad Sci U S A. 2022;119:e2103615119.
    PubMed     Abstract available


    May 2022
  8. LIN KING YH, Chen C, Lin King JV, Simms J, et al
    Kv1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis.
    Proc Natl Acad Sci U S A. 2022;119:e2118240119.
    PubMed     Abstract available


  9. KRAFT K, Yost KE, Murphy SE, Magg A, et al
    Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation.
    Proc Natl Acad Sci U S A. 2022;119:e2201883119.
    PubMed     Abstract available


  10. YANG Y, Gomez M, Marsh T, Poillet-Perez L, et al
    Autophagy in PDGFRalpha+ mesenchymal cells is essential for intestinal stem cell survival.
    Proc Natl Acad Sci U S A. 2022;119:e2202016119.
    PubMed     Abstract available


  11. JANG YJ, Kim M, Lee BK, Kim J, et al
    Induction of human trophoblast stem-like cells from primed pluripotent stem cells.
    Proc Natl Acad Sci U S A. 2022;119:e2115709119.
    PubMed     Abstract available


  12. CENIK BK, Sze CC, Ryan CA, Das S, et al
    A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells.
    Proc Natl Acad Sci U S A. 2022;119:e2118385119.
    PubMed     Abstract available


  13. SALVI JS, Kang J, Kim S, Colville AJ, et al
    ATR activity controls stem cell quiescence via the cyclin F-SCF complex.
    Proc Natl Acad Sci U S A. 2022;119:e2115638119.
    PubMed     Abstract available


    April 2022

  14. Correction for Song et al., Genetic studies of human-chimpanzee divergence using stem cell fusions.
    Proc Natl Acad Sci U S A. 2022;119:e2203826119.
    PubMed    


  15. TU J, Huo Z, Yu Y, Zhu D, et al
    Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies.
    Proc Natl Acad Sci U S A. 2022;119:e2117857119.
    PubMed     Abstract available


  16. LAROUCHE JA, Fraczek PM, Kurpiers SJ, Yang BA, et al
    Neutrophil and natural killer cell imbalances prevent muscle stem cell-mediated regeneration following murine volumetric muscle loss.
    Proc Natl Acad Sci U S A. 2022;119:e2111445119.
    PubMed     Abstract available


    March 2022
  17. ZHAO S, Feng S, Tian Y, Wen Z, et al
    Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage.
    Proc Natl Acad Sci U S A. 2022;119:e2119051119.
    PubMed     Abstract available


  18. AZEVEDO C, Teku G, Pomeshchik Y, Reyes JF, et al
    Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties.
    Proc Natl Acad Sci U S A. 2022;119:e2111405119.
    PubMed     Abstract available


  19. ZHANG Y, Li B, Cananzi S, Han C, et al
    A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum.
    Proc Natl Acad Sci U S A. 2022;119:e2107339119.
    PubMed     Abstract available


  20. KURNIAWAN F, Chetlangia N, Kamran M, Redon CE, et al
    BEND3 safeguards pluripotency by repressing differentiation-associated genes.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    February 2022
  21. SLOVAKOVA J, Sikora M, Arslan FN, Caballero-Mancebo S, et al
    Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  22. SMEDLER E, Louhivuori L, Romanov RA, Masini D, et al
    Disrupted Cacna1c gene expression perturbs spontaneous Ca(2+) activity causing abnormal brain development and increased anxiety.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  23. ZHAO H, Shi L, Li Z, Kong R, et al
    The Yun/Prohibitin complex regulates adult Drosophila intestinal stem cell proliferation through the transcription factor E2F1.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  24. ERICKSON JR, Stevens-Ayers T, Mair F, Edmison B, et al
    Convergent clonal selection of donor- and recipient-derived CMV-specific T cells in hematopoietic stem cell transplant patients.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  25. SOLOVIEVA T, Lu HC, Moverley A, Plachta N, et al
    The embryonic node behaves as an instructive stem cell niche for axial elongation.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  26. LAI LP, Fer N, Burgan W, Wall VE, et al
    Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  27. BHATTACHARJEE M, Escobar Ivirico JL, Kan HM, Shah S, et al
    Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  28. KANAGARAJ R, Mitter R, Kantidakis T, Edwards MM, et al
    Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  29. YU Z, Yang Z, Ren G, Wang Y, et al
    GATOR2 complex-mediated amino acid signaling regulates brain myelination.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  30. PAGE SC, Sripathy SR, Farinelli F, Ye Z, et al
    Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  31. SHAH S, Esdaille CJ, Bhattacharjee M, Kan HM, et al
    The synthetic artificial stem cell (SASC): Shifting the paradigm of cell therapy in regenerative engineering.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  32. GONZALEZ-BOHORQUEZ D, Gallego Lopez IM, Jaeger BN, Pfammatter S, et al
    FASN-dependent de novo lipogenesis is required for brain development.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  33. CORDERO A, Ramsey MD, Kanojia D, Fares J, et al
    Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  34. SONG JHT, Grant RL, Behrens VC, Kucka M, et al
    Genetic studies of human-chimpanzee divergence using stem cell fusions.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  35. JIN KX, Zuo R, Anastassiadis K, Klungland A, et al
    N6-methyladenosine (m(6)A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  36. ZHAO X, Hu J, Li Y, Guo M, et al
    Volumetric compression develops noise-driven single-cell heterogeneity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  37. ISAKOVA A, Neff N, Quake SR
    Single-cell quantification of a broad RNA spectrum reveals unique noncoding patterns associated with cell types and states.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  38. FREDRIKSEN K, Aivazidis S, Sharma K, Burbidge KJ, et al
    Pathological alpha-syn aggregation is mediated by glycosphingolipid chain length and the physiological state of alpha-syn in vivo.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  39. MUTO M, Chakraborty D, Varberg KM, Moreno-Irusta A, et al
    Intersection of regulatory pathways controlling hemostasis and hemochorial placentation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  40. SHIN JH, Jeong J, Maher SE, Lee HW, et al
    Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  41. LIU Y, Yang J, Che X, Huang J, et al
    Agonistic analog of growth hormone-releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  42. NIKHAT S, Yadavalli AD, Prusty A, Narayan PK, et al
    A regulatory network of microRNAs confers lineage commitment during early developmental trajectories of B and T lymphocytes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  43. BOMIDI C, Robertson M, Coarfa C, Estes MK, et al
    Single-cell sequencing of rotavirus-infected intestinal epithelium reveals cell-type specific epithelial repair and tuft cell infection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  44. SABHERWAL N, Rowntree A, Marinopoulou E, Pettini T, et al
    Differential phase register of Hes1 oscillations with mitoses underlies cell-cycle heterogeneity in ER(+) breast cancer cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  45. LIU X, Xie P, Hao N, Zhang M, et al
    HIF-1-regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/beta-catenin pathway activation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  46. CHEN G, Wang F, Nie M, Zhang H, et al
    Roe-inspired stem cell microcapsules for inflammatory bowel disease treatment.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  47. GARCIA-GARCIA A, Klein T, Born G, Hilpert M, et al
    Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  48. SEMENZA ER, Harraz MM, Abramson E, Malla AP, et al
    D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  49. JIMBO Y, Sasaki D, Ohya T, Lee S, et al
    An organic transistor matrix for multipoint intracellular action potential recording.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  50. KROEGER H, Grandjean JMD, Chiang WJ, Bindels DD, et al
    ATF6 is essential for human cone photoreceptor development.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  51. GKIKAS D, Stellas D, Polissidis A, Manolakou T, et al
    Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  52. KINOSHITA M, Li MA, Barber M, Mansfield W, et al
    Disabling de novo DNA methylation in embryonic stem cells allows an illegitimate fate trajectory.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  53. AGARWAL N, Rinaldetti S, Cheikh BB, Zhou Q, et al
    TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  54. DOI H, Matsuda T, Sakai A, Matsubara S, et al
    Early-life midazolam exposure persistently changes chromatin accessibility to impair adult hippocampal neurogenesis and cognition.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  55. LIU L, Rodriguez-Mateo C, Huang P, Huang A, et al
    Hairless regulates heterochromatin maintenance and muscle stem cell function as a histone demethylase antagonist.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  56. HORNBACHNER R, Lackner A, Papuchova H, Haider S, et al
    MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  57. XUE B, Tang D, Wu X, Xu Z, et al
    Engineering hydrogels with homogeneous mechanical properties for controlling stem cell lineage specification.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  58. XIE C, Jiang Y, Zhu Z, Huang S, et al
    Actin filament debranching regulates cell polarity during cell migration and asymmetric cell division.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  59. SARAAV I, Cervantes-Barragan L, Olias P, Fu Y, et al
    Chronic Toxoplasma gondii infection enhances susceptibility to colitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  60. SHANG E, Wang X, Li T, Guo F, et al
    Robust control of floral meristem determinacy by position-specific multifunctions of KNUCKLES.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  61. KWEE BJ, Lam J, Akue A, KuKuruga MA, et al
    Functional heterogeneity of IFN-gamma-licensed mesenchymal stromal cell immunosuppressive capacity on biomaterials.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  62. SCHLUSCHE AK, Vay SU, Kleinenkuhnen N, Sandke S, et al
    Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  63. KIM J, Chun K, McGowan J, Zhang Y, et al
    14-3-3zeta: A suppressor of inflammatory arthritis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  64. GARCIA-CASTILLO J, Alcaraz-Perez F, Martinez-Balsalobre E, Garcia-Moreno D, et al
    Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  65. Correction for Wang et al., Embryonic stem cell-derived hematopoietic stem cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  66. MATRONE G, Xia B, Chen K, Denvir MA, et al
    Fli1(+) cells transcriptional analysis reveals an Lmo2-Prdm16 axis in angiogenesis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  67. LANDAU S, Newman A, Edri S, Michael I, et al
    Investigating lymphangiogenesis in vitro and in vivo using engineered human lymphatic vessel networks.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021

  68. Correction for Canher et al., Rocks in the auxin stream: Wound-induced auxin accumulation and ERF115 expression synergistically drive stem cell regeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  69. LE ROLLE M, Massa F, Siggers P, Turchi L, et al
    Arrest of WNT/beta-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  70. AL TANOURY Z, Zimmerman JF, Rao J, Sieiro D, et al
    Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell-derived skeletal muscle in vitro.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  71. DEUSE T, Tediashvili G, Hu X, Gravina A, et al
    Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  72. BOTTES S, Jessberger S
    Live imaging of remyelination in the adult mouse corpus callosum.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  73. WEI GZ, Martin KA, Xing PY, Agrawal R, et al
    Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  74. MALLIS RJ, Duke-Cohan JS, Das DK, Akitsu A, et al
    Molecular design of the gammadeltaT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  75. YADAV PS, Feng S, Cong Q, Kim H, et al
    Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  76. PEBWORTH MP, Ross J, Andrews M, Bhaduri A, et al
    Human intermediate progenitor diversity during cortical development.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  77. XU T, Cheng, Zhao Y, Zhang J, et al
    Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  78. VENNEKENS A, Laporte E, Hermans F, Cox B, et al
    Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  79. YIN H, Wei C, Lee JT
    Revisiting the consequences of deleting the X inactivation center.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  80. YANG Y, Wang H, He J, Shi W, et al
    A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  81. RAVINDRAN S
    QnAs with Sean J. Morrison.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  82. VANDER ROEST AS, Liu C, Morck MM, Kooiker KB, et al
    Hypertrophic cardiomyopathy beta-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  83. MARKOV GJ, Mai T, Nair S, Shcherbina A, et al
    AP-1 is a temporally regulated dual gatekeeper of reprogramming to pluripotency.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  84. BATHE-PETERS M, Gmach P, Boltz HH, Einsiedel J, et al
    Visualization of beta-adrenergic receptor dynamics and differential localization in cardiomyocytes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  85. HU S, Fang Y, Chen X, Cheng T, et al
    cGAS restricts colon cancer development by protecting intestinal barrier integrity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  86. ALANIS-LOBATO G, Zohren J, McCarthy A, Fogarty NME, et al
    Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  87. PAK C, Danko T, Mirabella VR, Wang J, et al
    Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neurons.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  88. MUKHERJEE S, Paricio N, Sokol NS
    A stress-responsive miRNA regulates BMP signaling to maintain tissue homeostasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  89. LIANG Z, Kumar V, Le Bouteiller M, Zurita J, et al
    Ku70 suppresses alternative end joining in G1-arrested progenitor B cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  90. HAIDER T, Snetkov X, Jolly C
    HIV envelope tail truncation confers resistance to SERINC5 restriction.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  91. MORVAN MG, Teque F, Ye L, Moreno ME, et al
    Genetically edited CD34(+) cells derived from human iPS cells in vivo but not in vitro engraft and differentiate into HIV-resistant cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  92. MIDDELKOOP TC, Garcia-Baucells J, Quintero-Cadena P, Pimpale LG, et al
    CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left-right symmetry breaking.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  93. SCHAFER ST, Gage FH
    To eat, or not to eat, that is the question: Neural stem cells escape phagocytosis in autism with macrocephaly.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  94. BRIELLE S, Bavli D, Motzik A, Kan-Tor Y, et al
    Delineating the heterogeneity of matrix-directed differentiation toward soft and stiff tissue lineages via single-cell profiling.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  95. ZHAO H, Kim Y, Wang H, Ning X, et al
    Compliant 3D frameworks instrumented with strain sensors for characterization of millimeter-scale engineered muscle tissues.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  96. LE MERCIER A, Bonnavion R, Yu W, Alnouri MW, et al
    GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  97. CHAN A, Ma S, Pearson BJ, Chan D, et al
    Collagen IV differentially regulates planarian stem cell potency and lineage progression.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  98. ALVES DA COSTA T, Peterson JN, Lang J, Shulman J, et al
    Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  99. ZHAO L, Gao X, Zheng Y, Wang Z, et al
    Establishment of bovine expanded potential stem cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  100. TRUDLER D, Nazor KL, Eisele YS, Grabauskas T, et al
    Soluble alpha-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  101. LI J, Brickler T, Banuelos A, Marjon K, et al
    Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  102. XIA J, Kang Z, Xue Y, Ding Y, et al
    A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  103. SARDI J, Bener MB, Simao T, Descoteaux AE, et al
    Mad dephosphorylation at the nuclear pore is essential for asymmetric stem cell division.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  104. ZHOU S, Han L, Weng M, Zhu H, et al
    Paxbp1 controls a key checkpoint for cell growth and survival during early activation of quiescent muscle satellite cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  105. VERGOOSSEN DLE, Plomp JJ, Gstottner C, Fillie-Grijpma YE, et al
    Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  106. RELLA L, Fernandes Povoa EE, Mars J, Ebbing ALP, et al
    A switch from noncanonical to canonical Wnt signaling stops neuroblast migration through a Slt-Robo and RGA-9b/ARHGAP-dependent mechanism.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  107. DUPACOVA N, Antosova B, Paces J, Kozmik Z, et al
    Meis homeobox genes control progenitor competence in the retina.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  108. PIRIE E, Oh CK, Zhang X, Han X, et al
    S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  109. JU JM, Nam G, Lee YK, Jung M, et al
    IDO1 scavenges reactive oxygen species in myeloid-derived suppressor cells to prevent graft-versus-host disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  110. ZHANG ZZ, Zhang Y, He T, Sweeney CL, et al
    Homozygous IL37 mutation associated with infantile inflammatory bowel disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  111. BROSH R, Laurent JM, Ordonez R, Huang E, et al
    A versatile platform for locus-scale genome rewriting and verification.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  112. RUAN X, Kang B, Qi C, Lin W, et al
    Progenitor cell diversity in the developing mouse neocortex.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  113. VARBERG KM, Iqbal K, Muto M, Simon ME, et al
    ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  114. PITUCH KC, Zannikou M, Ilut L, Xiao T, et al
    Neural stem cells secreting bispecific T cell engager to induce selective antiglioma activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  115. RAJAGOPALAN KN, Chen X, Weinberg DN, Chen H, et al
    Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  116. LU TM, Houghton S, Magdeldin T, Duran JGB, et al
    Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  117. MONCHO-AMOR V, Chakravarty P, Galichet C, Matheu A, et al
    SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  118. HANEMAAIJER ES, Margaritis T, Sanders K, Bos FL, et al
    Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotype.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  119. SCHREIBER C, Amiri B, Heyn JCJ, Radler JO, et al
    On the adhesion-velocity relation and length adaptation of motile cells on stepped fibronectin lanes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  120. MURAKAMI K, Terakado Y, Saito K, Jomen Y, et al
    A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  121. SHIN B, Hosokawa H, Romero-Wolf M, Zhou W, et al
    Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  122. MOROZKO EL, Smith-Geater C, Monteys AM, Pradhan S, et al
    PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  123. STIRPARO GG, Kurowski A, Yanagida A, Bates LE, et al
    OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  124. CUI L, Moraga I, Lerbs T, Van Neste C, et al
    Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  125. UEBBING S, Gockley J, Reilly SK, Kocher AA, et al
    Massively parallel discovery of human-specific substitutions that alter enhancer activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  126. MASET A, Galla L, Francia S, Cozzolino O, et al
    Altered Cl(-) homeostasis hinders forebrain GABAergic interneuron migration in a mouse model of intellectual disability.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  127. FAN C, Zhao C, Zhang F, Kesarwani M, et al
    Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  128. ISHII S, Sasaki T, Mohammad S, Hwang H, et al
    Primary cilia safeguard cortical neurons in neonatal mouse forebrain from environmental stress-induced dendritic degeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  129. COPELAND J, Simoes-Costa M
    Post-transcriptional tuning of FGF signaling mediates neural crest induction.
    Proc Natl Acad Sci U S A. 2020;117:33305-33316.
    PubMed     Abstract available


  130. GAO Y, Chen X, He Q, Gimple RC, et al
    Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin.
    Proc Natl Acad Sci U S A. 2020;117:33295-33304.
    PubMed     Abstract available


  131. YANG L, Jama B, Wang H, Labarta-Bajo L, et al
    TCRalpha reporter mice reveal contribution of dual TCRalpha expression to T cell repertoire and function.
    Proc Natl Acad Sci U S A. 2020;117:32574-32583.
    PubMed     Abstract available


  132. LIU H, Zhang Y, Zhang YY, Li YP, et al
    Human embryonic stem cell-derived organoid retinoblastoma reveals a cancerous origin.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2011780117.
    PubMed     Abstract available


  133. SATTERLEE JW, Strable J, Scanlon MJ
    Plant stem-cell organization and differentiation at single-cell resolution.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2018788117.
    PubMed     Abstract available


  134. DONG A, Preusch CB, So WK, Lin K, et al
    A long noncoding RNA, LncMyoD, modulates chromatin accessibility to regulate muscle stem cell myogenic lineage progression.
    Proc Natl Acad Sci U S A. 2020 Dec 8. pii: 2005868117.
    PubMed     Abstract available


  135. WANG QW, Lu SY, Liu YN, Chen Y, et al
    Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity.
    Proc Natl Acad Sci U S A. 2020;117:31438-31447.
    PubMed     Abstract available


  136. ASLAM MA, Alemdehy MF, Hao B, Krijger PHL, et al
    The Ig heavy chain protein but not its message controls early B cell development.
    Proc Natl Acad Sci U S A. 2020;117:31343-31352.
    PubMed     Abstract available


  137. GUDMUNDSSON KO, Nguyen N, Oakley K, Han Y, et al
    Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence.
    Proc Natl Acad Sci U S A. 2020 Dec 2. pii: 2017626117.
    PubMed     Abstract available


    November 2020
  138. XIE XP, Laks DR, Sun D, Poran A, et al
    High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2014389117.
    PubMed     Abstract available


  139. TANG S, Zhang M, Zeng S, Huang Y, et al
    Reversal of autoimmunity by mixed chimerism enables reactivation of beta cells and transdifferentiation of alpha cells in diabetic NOD mice.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2012389117.
    PubMed     Abstract available


  140. LEE JP, Zhang R, Yan M, Duggineni S, et al
    Chemical mutagenesis of a GPCR ligand: Detoxifying "inflammo-attraction" to direct therapeutic stem cell migration.
    Proc Natl Acad Sci U S A. 2020 Nov 20. pii: 1911444117.
    PubMed     Abstract available


  141. ZHANG T, Periz G, Lu YN, Wang J, et al
    USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway.
    Proc Natl Acad Sci U S A. 2020;117:28114-28125.
    PubMed     Abstract available


  142. LIN RJ, Kuo MW, Yang BC, Tsai HH, et al
    B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naive pluripotency.
    Proc Natl Acad Sci U S A. 2020;117:27435-27444.
    PubMed     Abstract available


  143. CAO K, Ugarenko M, Ozark PA, Wang J, et al
    DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation.
    Proc Natl Acad Sci U S A. 2020;117:27365-27373.
    PubMed     Abstract available


  144. JAIN SU, Khazaei S, Marchione DM, Lundgren SM, et al
    Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
    Proc Natl Acad Sci U S A. 2020;117:27354-27364.
    PubMed     Abstract available


  145. ROSENBLOOM AB, Tarczynski M, Lam N, Kane RS, et al
    beta-Catenin signaling dynamics regulate cell fate in differentiating neural stem cells.
    Proc Natl Acad Sci U S A. 2020 Nov 2. pii: 2008509117.
    PubMed     Abstract available


    October 2020
  146. GROLMAN JM, Weinand P, Mooney DJ
    Extracellular matrix plasticity as a driver of cell spreading.
    Proc Natl Acad Sci U S A. 2020;117:25999-26007.
    PubMed     Abstract available


  147. ZHANG L, Jing H, Li H, Chen W, et al
    Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling.
    Proc Natl Acad Sci U S A. 2020;117:26448-26459.
    PubMed     Abstract available


    September 2020
  148. HSU J, Huang HT, Lee CT, Choudhuri A, et al
    CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation.
    Proc Natl Acad Sci U S A. 2020;117:23626-23635.
    PubMed     Abstract available


  149. HE Z, An S, Chen J, Zhang S, et al
    Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
    Proc Natl Acad Sci U S A. 2020 Sep 9. pii: 2007773117.
    PubMed     Abstract available


  150. SOOD S, Weber CM, Hodges HC, Krokhotin A, et al
    CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation.
    Proc Natl Acad Sci U S A. 2020;117:22331-22340.
    PubMed     Abstract available


  151. YIN Y, Cao S, Fu H, Fan X, et al
    A noncanonical role of NOD-like receptor NLRP14 in PGCLC differentiation and spermatogenesis.
    Proc Natl Acad Sci U S A. 2020;117:22237-22248.
    PubMed     Abstract available


  152. HUANG D, Abbott RK, Havenar-Daughton C, Skog PD, et al
    B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
    Proc Natl Acad Sci U S A. 2020 Sep 1. pii: 2004489117.
    PubMed     Abstract available


  153. KILLAARS AR, Walker CJ, Anseth KS
    Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling.
    Proc Natl Acad Sci U S A. 2020;117:21258-21266.
    PubMed     Abstract available


  154. LJUNGGREN-ROSE A, Natarajan C, Matta P, Pandey A, et al
    Anacardic acid induces IL-33 and promotes remyelination in CNS.
    Proc Natl Acad Sci U S A. 2020;117:21527-21535.
    PubMed     Abstract available


    August 2020
  155. WANG X, Sathe AA, Smith GR, Ruf-Zamojski F, et al
    Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages.
    Proc Natl Acad Sci U S A. 2020;117:20729-20740.
    PubMed     Abstract available


  156. SANGOKOYA C, Blelloch R
    MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis.
    Proc Natl Acad Sci U S A. 2020;117:20625-20635.
    PubMed     Abstract available


  157. ROUDNICKY F, Zhang JD, Kim BK, Pandya NJ, et al
    Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells.
    Proc Natl Acad Sci U S A. 2020;117:19854-19865.
    PubMed     Abstract available


  158. LEE CM, Zhou L, Liu J, Shi J, et al
    Single-cell RNA-seq analysis revealed long-lasting adverse effects of tamoxifen on neurogenesis in prenatal and adult brains.
    Proc Natl Acad Sci U S A. 2020;117:19578-19589.
    PubMed     Abstract available


  159. BERNSTEIN SL, Guo Y, Kerr C, Fawcett RJ, et al
    The optic nerve lamina region is a neural progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020;117:19287-19298.
    PubMed     Abstract available


  160. LIU J, Huang ZP, Nie M, Wang G, et al
    Regulation of myonuclear positioning and muscle function by the skeletal muscle-specific CIP protein.
    Proc Natl Acad Sci U S A. 2020;117:19254-19265.
    PubMed     Abstract available


    July 2020
  161. PHAN QT, Tan WH, Liu R, Sundaram S, et al
    Cxcl9l and Cxcr3.2 regulate recruitment of osteoclast progenitors to bone matrix in a medaka osteoporosis model.
    Proc Natl Acad Sci U S A. 2020 Jul 27. pii: 2006093117.
    PubMed     Abstract available


  162. GHOSH S, Basu Ball W, Madaris TR, Srikantan S, et al
    An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter.
    Proc Natl Acad Sci U S A. 2020;117:16383-16390.
    PubMed     Abstract available


  163. LIM KRQ, Maruyama R, Echigoya Y, Nguyen Q, et al
    Inhibition of DUX4 expression with antisense LNA gapmers as a therapy for facioscapulohumeral muscular dystrophy.
    Proc Natl Acad Sci U S A. 2020;117:16509-16515.
    PubMed     Abstract available


    June 2020
  164. BUCHHOLZ DE, Carroll TS, Kocabas A, Zhu X, et al
    Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics.
    Proc Natl Acad Sci U S A. 2020;117:15085-15095.
    PubMed     Abstract available


Thank you for your interest in scientific medicine.


AMEDEO Stem Cell Research is free of charge.
This policy is made possible thanks to a media sponsorship by Boehringer Ingelheim.

Design: