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  Stem Cell Research

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Articles published in Proc Natl Acad Sci U S A

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Single Articles


    April 2024
  1. LORENZO JP, Molla L, Amro EM, Ibarra IL, et al
    APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation.
    Proc Natl Acad Sci U S A. 2024;121:e2312330121.
    PubMed     Abstract available


  2. HIYOSHI H, Sakuma K, Asano S, Napier SC, et al
    Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation.
    Proc Natl Acad Sci U S A. 2024;121:e2320883121.
    PubMed     Abstract available


    March 2024
  3. YU Y, Su Y, Wang G, Lan M, et al
    Reciprocal communication between FAPs and muscle cells via distinct extracellular vesicle miRNAs in muscle regeneration.
    Proc Natl Acad Sci U S A. 2024;121:e2316544121.
    PubMed     Abstract available


  4. RADMAND A, Kim H, Beyersdorf J, Dobrowolski CN, et al
    Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heart.
    Proc Natl Acad Sci U S A. 2024;121:e2307801120.
    PubMed     Abstract available


  5. JIANG Y, Huang H, Liu J, Luo D, et al
    Hippo cooperates with p53 to maintain foregut homeostasis and suppress the malignant transformation of foregut basal progenitor cells.
    Proc Natl Acad Sci U S A. 2024;121:e2320559121.
    PubMed     Abstract available


  6. KATSUMURA KR, Liu P, Kim JA, Mehta C, et al
    Pathogenic GATA2 genetic variants utilize an obligate enhancer mechanism to distort a multilineage differentiation program.
    Proc Natl Acad Sci U S A. 2024;121:e2317147121.
    PubMed     Abstract available


    February 2024
  7. LIU Q, Luo X, Liang Z, Qin D, et al
    Coordination between circadian neural circuit and intracellular molecular clock ensures rhythmic activation of adult neural stem cells.
    Proc Natl Acad Sci U S A. 2024;121:e2318030121.
    PubMed     Abstract available


  8. YI W, Xue Y, Qing W, Cao Y, et al
    Effective treatment of optic neuropathies by intraocular delivery of MSC-sEVs through augmenting the G-CSF-macrophage pathway.
    Proc Natl Acad Sci U S A. 2024;121:e2305947121.
    PubMed     Abstract available


    January 2024
  9. RODERICK-RICHARDSON JE, Lim SE, Suzuki S, Ahmad MH, et al
    ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2309628121.
    PubMed     Abstract available


  10. FENG J, Jang G, Esteva E, Adams NM, et al
    Clonal barcoding of endogenous adult hematopoietic stem cells reveals a spectrum of lineage contributions.
    Proc Natl Acad Sci U S A. 2024;121:e2317929121.
    PubMed     Abstract available


  11. URENA E, Xu B, Regan JC, Atilano ML, et al
    Trametinib ameliorates aging-associated gut pathology in Drosophila females by reducing Pol III activity in intestinal stem cells.
    Proc Natl Acad Sci U S A. 2024;121:e2311313121.
    PubMed     Abstract available


  12. HUANG LC, McKeown CR, He HY, Ta AC, et al
    BRCA1 and ELK-1 regulate neural progenitor cell fate in the optic tectum in response to visual experience in Xenopus laevis tadpoles.
    Proc Natl Acad Sci U S A. 2024;121:e2316542121.
    PubMed     Abstract available


    December 2023
  13. SHIMIZU T, Oike A, Kobayashi EH, Sekiya A, et al
    CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development.
    Proc Natl Acad Sci U S A. 2023;120:e2311372120.
    PubMed     Abstract available


  14. JIN L, Chen Y, Muzaffar S, Li C, et al
    Epigenetic switch reshapes epithelial progenitor cell signatures and drives inflammatory pathogenesis in hidradenitis suppurativa.
    Proc Natl Acad Sci U S A. 2023;120:e2315096120.
    PubMed     Abstract available


    November 2023
  15. NELSON JO, Kumon T, Yamashita YM
    rDNA magnification is a unique feature of germline stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2314440120.
    PubMed     Abstract available


  16. MILLER N, Xu Z, Quinlan KA, Ji A, et al
    Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy.
    Proc Natl Acad Sci U S A. 2023;120:e2300308120.
    PubMed     Abstract available


  17. SOUCY JR, Todd L, Kriukov E, Phay M, et al
    Controlling donor and newborn neuron migration and maturation in the eye through microenvironment engineering.
    Proc Natl Acad Sci U S A. 2023;120:e2302089120.
    PubMed     Abstract available


  18. CHEN R, Dong H, Raval D, Maridas D, et al
    Sfrp4 is required to maintain Ctsk-lineage periosteal stem cell niche function.
    Proc Natl Acad Sci U S A. 2023;120:e2312677120.
    PubMed     Abstract available


  19. DINARELLO A, May M, Amo-Aparicio J, Azam T, et al
    IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1beta secretion.
    Proc Natl Acad Sci U S A. 2023;120:e2306476120.
    PubMed     Abstract available


  20. HO KYL, An K, Carr RL, Dvoskin AD, et al
    Maintenance of hematopoietic stem cell niche homeostasis requires gap junction-mediated calcium signaling.
    Proc Natl Acad Sci U S A. 2023;120:e2303018120.
    PubMed     Abstract available


    October 2023
  21. NG A, Lovat F, Shih AJ, Ma Y, et al
    Complete miRNA-15/16 loss in mice promotes hematopoietic progenitor expansion and a myeloid-biased hyperproliferative state.
    Proc Natl Acad Sci U S A. 2023;120:e2308658120.
    PubMed     Abstract available


  22. INCARBONE M, Bradamante G, Pruckner F, Wegscheider T, et al
    Salicylic acid and RNA interference mediate antiviral immunity of plant stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2302069120.
    PubMed     Abstract available


    September 2023
  23. FERDOUS AS, Lynch TR, Costa Dos Santos SJ, Kapadia DH, et al
    LST-1 is a bifunctional regulator that feeds back on Notch-dependent transcription to regulate C. elegans germline stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2309964120.
    PubMed     Abstract available


  24. WOODHAMS LG, Guo J, Schuftan D, Boyle JJ, et al
    Virtual blebbistatin: A robust and rapid software approach to motion artifact removal in optical mapping of cardiomyocytes.
    Proc Natl Acad Sci U S A. 2023;120:e2212949120.
    PubMed     Abstract available


    August 2023
  25. TU R, Tang XA, Xu R, Ping Z, et al
    Gap junction-transported cAMP from the niche controls stem cell progeny differentiation.
    Proc Natl Acad Sci U S A. 2023;120:e2304168120.
    PubMed     Abstract available


  26. TAKUBO K, Htun PW, Ueda T, Sera Y, et al
    MBTD1 preserves adult hematopoietic stem cell pool size and function.
    Proc Natl Acad Sci U S A. 2023;120:e2206860120.
    PubMed     Abstract available


    July 2023
  27. HEILAND M, Connolly NMC, Mamad O, Nguyen NT, et al
    MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control.
    Proc Natl Acad Sci U S A. 2023;120:e2216658120.
    PubMed     Abstract available


  28. JIANG F, Wang L, Dong Y, Nie W, et al
    DPPA5A suppresses the mutagenic TLS and MMEJ pathways by modulating the cryptic splicing of Rev1 and Polq in mouse embryonic stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2305187120.
    PubMed     Abstract available


  29. TANG J, Jia X, Li Q, Cui Z, et al
    A DNA-based hydrogel for exosome separation and biomedical applications.
    Proc Natl Acad Sci U S A. 2023;120:e2303822120.
    PubMed     Abstract available


  30. VAN VOORDEN AJ, Keijser R, Veenboer GJM, Lopes Cardozo SA, et al
    EP300 facilitates human trophoblast stem cell differentiation.
    Proc Natl Acad Sci U S A. 2023;120:e2217405120.
    PubMed     Abstract available


    June 2023
  31. LIANG Z, Zhao L, Ye AY, Lin SG, et al
    Contribution of the IGCR1 regulatory element and the 3'Igh CTCF-binding elements to regulation of Igh V(D)J recombination.
    Proc Natl Acad Sci U S A. 2023;120:e2306564120.
    PubMed     Abstract available


  32. PARIKH BH, Blakeley P, Regha K, Liu Z, et al
    Single-cell transcriptomics reveals maturation of transplanted stem cell-derived retinal pigment epithelial cells toward native state.
    Proc Natl Acad Sci U S A. 2023;120:e2214842120.
    PubMed     Abstract available


  33. CONCHOLA AS, Frum T, Xiao Z, Hsu PP, et al
    Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung.
    Proc Natl Acad Sci U S A. 2023;120:e2210113120.
    PubMed     Abstract available


    May 2023
  34. JANG G, Contreras Castillo S, Esteva E, Upadhaya S, et al
    Stem cell decoupling underlies impaired lymphoid development during aging.
    Proc Natl Acad Sci U S A. 2023;120:e2302019120.
    PubMed     Abstract available


  35. SAMPAYO RG, Sakamoto M, Wang M, Kumar S, et al
    Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases.
    Proc Natl Acad Sci U S A. 2023;120:e2219854120.
    PubMed     Abstract available


  36. WANG J, Fu Y, Huang W, Biswas R, et al
    MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2220635120.
    PubMed     Abstract available


  37. JIN Y, Lu Y, Lin L, Liu C, et al
    Harnessing endogenous transcription factors directly by small molecules for chemically induced pluripotency inception.
    Proc Natl Acad Sci U S A. 2023;120:e2215155120.
    PubMed     Abstract available


  38. KIM JH, Park S, Jung E, Shin J, et al
    A dual-action niclosamide-based prodrug that targets cancer stem cells and inhibits TNBC metastasis.
    Proc Natl Acad Sci U S A. 2023;120:e2304081120.
    PubMed     Abstract available


  39. SHAO L, Paik NY, Sanborn MA, Bandara T, et al
    Hematopoietic Jagged1 is a fetal liver niche factor required for functional maturation and engraftment of fetal hematopoietic stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2210058120.
    PubMed     Abstract available


  40. LAMANDE SR, Ng ES, Cameron TL, Kung LHW, et al
    Modeling human skeletal development using human pluripotent stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2211510120.
    PubMed     Abstract available


  41. WANG J, Li X, Chen X, Tang W, et al
    Dual regulations of cell cycle regulator DPa by auxin in Arabidopsis root distal stem cell maintenance.
    Proc Natl Acad Sci U S A. 2023;120:e2218503120.
    PubMed     Abstract available


  42. CHANG YJ, Jenny LA, Li YS, Cui X, et al
    CRISPR editing demonstrates rs10490924 raised oxidative stress in iPSC-derived retinal cells from patients with ARMS2/HTRA1-related AMD.
    Proc Natl Acad Sci U S A. 2023;120:e2215005120.
    PubMed     Abstract available


  43. SPORRIJ A, Choudhuri A, Prasad M, Muhire B, et al
    PGE(2) alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate.
    Proc Natl Acad Sci U S A. 2023;120:e2220613120.
    PubMed     Abstract available


  44. CRABTREE AA, Boehnke N, Bates FS, Hackel BJ, et al
    Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts.
    Proc Natl Acad Sci U S A. 2023;120:e2219885120.
    PubMed     Abstract available


  45. TIAN Y, Morin-Poulard I, Liu X, Vanzo N, et al
    A mechanosensitive vascular niche for Drosophila hematopoiesis.
    Proc Natl Acad Sci U S A. 2023;120:e2217862120.
    PubMed     Abstract available


    April 2023
  46. ALDAWOOD ZA, Mancinelli L, Geng X, Yeh SA, et al
    Expansion of the sagittal suture induces proliferation of skeletal stem cells and sustains endogenous calvarial bone regeneration.
    Proc Natl Acad Sci U S A. 2023;120:e2120826120.
    PubMed     Abstract available


  47. MATSUDA Y, Uchimura A, Satoh Y, Kato N, et al
    Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2216550120.
    PubMed     Abstract available


  48. GUPTA M, Walters BA, Katsara O, Granados Blanco K, et al
    eIF2Bdelta blocks the integrated stress response and maintains eIF2B activity and cancer metastasis by overexpression in breast cancer stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2207898120.
    PubMed     Abstract available


  49. LLEWELLYN J, Mallikarjun V, Appleton E, Osipova M, et al
    Loss of regulation of protein synthesis and turnover underpins an attenuated stress response in senescent human mesenchymal stem cells.
    Proc Natl Acad Sci U S A. 2023;120:e2210745120.
    PubMed     Abstract available


    March 2023
  50. XUE Y, San Luis B, Dress RJ, Murad KBA, et al
    Proteasome inhibitor bortezomib stabilizes and activates p53 in hematopoietic stem/progenitors and double-negative T cells in vivo.
    Proc Natl Acad Sci U S A. 2023;120:e2219978120.
    PubMed     Abstract available


    February 2023
  51. MARTINEZ RJ, Breed ER, Worota Y, Ashby KM, et al
    Type III interferon drives thymic B cell activation and regulatory T cell generation.
    Proc Natl Acad Sci U S A. 2023;120:e2220120120.
    PubMed     Abstract available


  52. KUO CS, Dobi S, Gok C, Da Silva Costa A, et al
    Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes.
    Proc Natl Acad Sci U S A. 2023;120:e2207887120.
    PubMed     Abstract available


  53. YOUSEF YENGEJ FA, Jansen J, Ammerlaan CME, Dilmen E, et al
    Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids.
    Proc Natl Acad Sci U S A. 2023;120:e2216836120.
    PubMed     Abstract available


  54. EGUCHI A, Gonzalez AFGS, Torres-Bigio SI, Koleckar K, et al
    TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs.
    Proc Natl Acad Sci U S A. 2023;120:e2209967120.
    PubMed     Abstract available


    January 2023
  55. FORTIN J, Chiang MF, Meydan C, Foox J, et al
    Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells.
    Proc Natl Acad Sci U S A. 2023;120:e2208176120.
    PubMed     Abstract available


  56. GENEROSO SF, Neguembor MV, Hershberg EA, Sadreyev RI, et al
    Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming.
    Proc Natl Acad Sci U S A. 2023;120:e2213810120.
    PubMed     Abstract available


  57. BUONINFANTE OA, Pilzecker B, Spanjaard A, de Groot D, et al
    Mammalian life depends on two distinct pathways of DNA damage tolerance.
    Proc Natl Acad Sci U S A. 2023;120:e2216055120.
    PubMed     Abstract available


  58. LUDWIG AL, Mayerl SJ, Gao Y, Banghart M, et al
    Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures.
    Proc Natl Acad Sci U S A. 2023;120:e2213418120.
    PubMed     Abstract available


  59. WU J, Li J, Chen K, Liu G, et al
    Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation.
    Proc Natl Acad Sci U S A. 2023;120:e2209062120.
    PubMed     Abstract available


    December 2022
  60. FALICK MICHAELI T, Sabag O, Fok R, Azria B, et al
    Muscle injury causes long-term changes in stem-cell DNA methylation.
    Proc Natl Acad Sci U S A. 2022;119:e2212306119.
    PubMed     Abstract available


  61. JEYARAJAH MJ, Jaju Bhattad G, Kelly RD, Baines KJ, et al
    The multifaceted role of GCM1 during trophoblast differentiation in the human placenta.
    Proc Natl Acad Sci U S A. 2022;119:e2203071119.
    PubMed     Abstract available


  62. CHENG WY, Li JF, Zhu YM, Lin XJ, et al
    Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2022;119:e2211429119.
    PubMed     Abstract available


    November 2022
  63. BUCHANAN J, Elabbady L, Collman F, Jorstad NL, et al
    Oligodendrocyte precursor cells ingest axons in the mouse neocortex.
    Proc Natl Acad Sci U S A. 2022;119:e2202580119.
    PubMed     Abstract available


  64. ZOLOTAREV N, Bayer M, Grosschedl R
    EBF1 is continuously required for stabilizing local chromatin accessibility in pro-B cells.
    Proc Natl Acad Sci U S A. 2022;119:e2210595119.
    PubMed     Abstract available


  65. DIERCKX T, Vanherle S, Haidar M, Grajchen E, et al
    Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation.
    Proc Natl Acad Sci U S A. 2022;119:e2120393119.
    PubMed     Abstract available


    October 2022
  66. SPEICHER AM, Korn L, Csatari J, Gonzalez-Cano L, et al
    Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease.
    Proc Natl Acad Sci U S A. 2022;119:e2123476119.
    PubMed     Abstract available


  67. ZHANG J, Zhou Y, Yue W, Zhu Z, et al
    Super-enhancers conserved within placental mammals maintain stem cell pluripotency.
    Proc Natl Acad Sci U S A. 2022;119:e2204716119.
    PubMed     Abstract available


  68. AHERN DT, Bansal P, Armillei MK, Faustino IV, et al
    Monosomy X in isogenic human iPSC-derived trophoblast model impacts expression modules preserved in human placenta.
    Proc Natl Acad Sci U S A. 2022;119:e2211073119.
    PubMed     Abstract available


  69. GANGULI A, Lim J, Mostafa A, Saavedra C, et al
    A culture-free biphasic approach for sensitive and rapid detection of pathogens in dried whole-blood matrix.
    Proc Natl Acad Sci U S A. 2022;119:e2209607119.
    PubMed     Abstract available


    September 2022

  70. Correction for Lan et al., Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment.
    Proc Natl Acad Sci U S A. 2022;119:e2210925119.
    PubMed    



  71. Retraction for Samanta et al., Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells.
    Proc Natl Acad Sci U S A. 2022;119:e2213289119.
    PubMed    


  72. GAMAGE DG, Melikov K, Munoz-Tello P, Wherley TJ, et al
    Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion.
    Proc Natl Acad Sci U S A. 2022;119:e2202490119.
    PubMed     Abstract available


  73. WANG L, Park JY, Liu F, Olesen KM, et al
    A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding.
    Proc Natl Acad Sci U S A. 2022;119:e2206147119.
    PubMed     Abstract available


  74. LACH RS, Qiu C, Kajbaf EZ, Baxter N, et al
    Nucleation of the destruction complex on the centrosome accelerates degradation of beta-catenin and regulates Wnt signal transmission.
    Proc Natl Acad Sci U S A. 2022;119:e2204688119.
    PubMed     Abstract available


  75. WANG Y, Liu J, Akatsu C, Zhang R, et al
    LAPTM5 mediates immature B cell apoptosis and B cell tolerance by regulating the WWP2-PTEN-AKT pathway.
    Proc Natl Acad Sci U S A. 2022;119:e2205629119.
    PubMed     Abstract available


    August 2022
  76. KUROTAKI D, Kikuchi K, Cui K, Kawase W, et al
    Chromatin structure undergoes global and local reorganization during murine dendritic cell development and activation.
    Proc Natl Acad Sci U S A. 2022;119:e2207009119.
    PubMed     Abstract available


  77. ARNOVITZ S, Mathur P, Tracy M, Mohsin A, et al
    Tcf-1 promotes genomic instability and T cell transformation in response to aberrant beta-catenin activation.
    Proc Natl Acad Sci U S A. 2022;119:e2201493119.
    PubMed     Abstract available


  78. LANG E, Pedersen C, Lang A, Blicher P, et al
    Mechanical coupling of supracellular stress amplification and tissue fluidization during exit from quiescence.
    Proc Natl Acad Sci U S A. 2022;119:e2201328119.
    PubMed     Abstract available


    July 2022
  79. COELHO DR, Palma FR, Paviani V, He C, et al
    Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
    Proc Natl Acad Sci U S A. 2022;119:e2110348119.
    PubMed     Abstract available


  80. KASTAN NR, Oak S, Liang R, Baxt L, et al
    Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs.
    Proc Natl Acad Sci U S A. 2022;119:e2206113119.
    PubMed     Abstract available


  81. OLIVEROS A, Yoo KH, Rashid MA, Corujo-Ramirez A, et al
    Adenosine A2A receptor blockade prevents cisplatin-induced impairments in neurogenesis and cognitive function.
    Proc Natl Acad Sci U S A. 2022;119:e2206415119.
    PubMed     Abstract available


    June 2022
  82. XU J, Liu Y, Li H, Tarashansky AJ, et al
    Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing.
    Proc Natl Acad Sci U S A. 2022;119:e2203179119.
    PubMed     Abstract available


  83. LI W, Zhu Z, He K, Ma X, et al
    Primary cilia in satellite cells are the mechanical sensors for muscle hypertrophy.
    Proc Natl Acad Sci U S A. 2022;119:e2103615119.
    PubMed     Abstract available


    May 2022
  84. LIN KING YH, Chen C, Lin King JV, Simms J, et al
    Kv1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis.
    Proc Natl Acad Sci U S A. 2022;119:e2118240119.
    PubMed     Abstract available


  85. KRAFT K, Yost KE, Murphy SE, Magg A, et al
    Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation.
    Proc Natl Acad Sci U S A. 2022;119:e2201883119.
    PubMed     Abstract available


  86. YANG Y, Gomez M, Marsh T, Poillet-Perez L, et al
    Autophagy in PDGFRalpha+ mesenchymal cells is essential for intestinal stem cell survival.
    Proc Natl Acad Sci U S A. 2022;119:e2202016119.
    PubMed     Abstract available


  87. JANG YJ, Kim M, Lee BK, Kim J, et al
    Induction of human trophoblast stem-like cells from primed pluripotent stem cells.
    Proc Natl Acad Sci U S A. 2022;119:e2115709119.
    PubMed     Abstract available


  88. CENIK BK, Sze CC, Ryan CA, Das S, et al
    A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells.
    Proc Natl Acad Sci U S A. 2022;119:e2118385119.
    PubMed     Abstract available


  89. SALVI JS, Kang J, Kim S, Colville AJ, et al
    ATR activity controls stem cell quiescence via the cyclin F-SCF complex.
    Proc Natl Acad Sci U S A. 2022;119:e2115638119.
    PubMed     Abstract available


    April 2022

  90. Correction for Song et al., Genetic studies of human-chimpanzee divergence using stem cell fusions.
    Proc Natl Acad Sci U S A. 2022;119:e2203826119.
    PubMed    


  91. TU J, Huo Z, Yu Y, Zhu D, et al
    Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies.
    Proc Natl Acad Sci U S A. 2022;119:e2117857119.
    PubMed     Abstract available


  92. LAROUCHE JA, Fraczek PM, Kurpiers SJ, Yang BA, et al
    Neutrophil and natural killer cell imbalances prevent muscle stem cell-mediated regeneration following murine volumetric muscle loss.
    Proc Natl Acad Sci U S A. 2022;119:e2111445119.
    PubMed     Abstract available


    March 2022
  93. ZHAO S, Feng S, Tian Y, Wen Z, et al
    Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage.
    Proc Natl Acad Sci U S A. 2022;119:e2119051119.
    PubMed     Abstract available


  94. AZEVEDO C, Teku G, Pomeshchik Y, Reyes JF, et al
    Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties.
    Proc Natl Acad Sci U S A. 2022;119:e2111405119.
    PubMed     Abstract available


  95. ZHANG Y, Li B, Cananzi S, Han C, et al
    A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum.
    Proc Natl Acad Sci U S A. 2022;119:e2107339119.
    PubMed     Abstract available


  96. KURNIAWAN F, Chetlangia N, Kamran M, Redon CE, et al
    BEND3 safeguards pluripotency by repressing differentiation-associated genes.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    February 2022
  97. SLOVAKOVA J, Sikora M, Arslan FN, Caballero-Mancebo S, et al
    Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  98. SMEDLER E, Louhivuori L, Romanov RA, Masini D, et al
    Disrupted Cacna1c gene expression perturbs spontaneous Ca(2+) activity causing abnormal brain development and increased anxiety.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  99. ZHAO H, Shi L, Li Z, Kong R, et al
    The Yun/Prohibitin complex regulates adult Drosophila intestinal stem cell proliferation through the transcription factor E2F1.
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