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Articles published in Ann Intern Med

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    April 2021
  1. HILL MD
    In imaging-selected ischemic stroke with unknown onset, alteplase increases favorable outcomes and death at 90 d.
    Ann Intern Med. 2021 Apr 6. doi: 10.7326/ACPJ202104200.
    PubMed     Abstract available


    March 2021
  2. DAWWAS GK, Dietrich E, Cuker A, Barnes GD, et al
    Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation : A Population-Based Cohort Study.
    Ann Intern Med. 2021 Mar 30. doi: 10.7326/M20-6194.
    PubMed     Abstract available


    January 2021
  3. STEINBERG DI
    In older patients with AF, low-dose edoxaban reduced stroke or systemic embolism without increasing major bleeding.
    Ann Intern Med. 2021;174:JC5.
    PubMed     Abstract available


    December 2020
  4. HILL MD
    In acute ischemic stroke or TIA, adding ticagrelor to aspirin reduced stroke or death and increased severe bleeding.
    Ann Intern Med. 2020;173:JC63.
    PubMed     Abstract available


  5. AGGARWAL G, Aggarwal S, Cohen M
    Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence.
    Ann Intern Med. 2020;173:945.
    PubMed    


  6. KUMAR P, Mojadidi MK, Tobis JM
    Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence.
    Ann Intern Med. 2020;173:944-945.
    PubMed    


  7. KARAGIANNI A, Eriksson P, Dellborg M
    Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence.
    Ann Intern Med. 2020;173:945-946.
    PubMed    


  8. DENG W, Yin S, McMullin D, Inglessis-Azuaje I, et al
    Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence.
    Ann Intern Med. 2020;173:946-947.
    PubMed    


    September 2020
  9. ALBERTS MJ
    In ischemic stroke, thrombectomy alone was noninferior to thrombectomy plus alteplase for functional outcome at 90 days.
    Ann Intern Med. 2020;173:JC31.
    PubMed     Abstract available


  10. ELGENDY IY
    In established atherosclerosis, P2Y12 inhibitor vs. aspirin monotherapy reduces MI but not stroke or mortality.
    Ann Intern Med. 2020;173:JC26.
    PubMed     Abstract available


    July 2020
  11. ANDERSON MR, Geleris J, Anderson DR, Zucker J, et al
    Body Mass Index and Risk for Intubation or Death in SARS-CoV-2 Infection: A Retrospective Cohort Study.
    Ann Intern Med. 2020 Jul 29. doi: 10.7326/M20-3214.
    PubMed     Abstract available


    June 2020
  12. KUSSMAUL WG 3RD
    Different Strokes.
    Ann Intern Med. 2020;172:761-762.
    PubMed    


  13. DENG W, Yin S, McMullin D, Inglessis-Azuaje I, et al
    Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence: A Prospective Cohort Study.
    Ann Intern Med. 2020;172:717-725.
    PubMed     Abstract available


    May 2020
  14. HILL MD
    In ischemic stroke with viable hypoperfused tissue, alteplase > 4.5 h after last seen well improves function.
    Ann Intern Med. 2020;172:JC50.
    PubMed     Abstract available


  15. HIRSCH C
    In older adults with acute ischemic stroke, the Clinical Frailty Scale predicted mortality at 28 days.
    Ann Intern Med. 2020;172:JC57.
    PubMed     Abstract available


  16. LAU WCY, Cheung CL, Man KKC, Chan EW, et al
    Association Between Treatment With Apixaban, Dabigatran, Rivaroxaban, or Warfarin and Risk for Osteoporotic Fractures Among Patients With Atrial Fibrillation.
    Ann Intern Med. 2020 May 19. doi: 10.7326/M19-3671.
    PubMed     Abstract available


    March 2020
  17. DUNN A
    In AF, DOACs were linked to lower risk for osteoporotic fractures at 2 years compared with VKAs.
    Ann Intern Med. 2020;172:JC35.
    PubMed    


  18. DUNN A
    In AF, DOACs were linked to lower risk for clinical fracture at 17 months compared with warfarin.
    Ann Intern Med. 2020;172:JC34.
    PubMed    


  19. FRALICK M, Colacci M, Schneeweiss S, Huybrechts KF, et al
    Effectiveness and Safety of Apixaban Compared With Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study.
    Ann Intern Med. 2020 Mar 10. pii: 2762724. doi: 10.7326/M19-2522.
    PubMed     Abstract available



  20. Effectiveness and Safety of Apixaban Versus Rivaroxaban for Patients With Atrial Fibrillation.
    Ann Intern Med. 2020 Mar 10. pii: 2762725. doi: 10.7326/P20-0003.
    PubMed    


    January 2020
  21. RACO DL
    In ACS with planned invasive evaluation, prasugrel vs ticagrelor reduced a composite of death, MI, or stroke at 1 y.
    Ann Intern Med. 2020;172:JC5.
    PubMed    


    December 2019
  22. HANKEY GJ
    In acute ischemic stroke with potentially salvageable tissue, thrombectomy at 6 to 16 h increased living at home.
    Ann Intern Med. 2019;171:JC66.
    PubMed    


    November 2019
  23. PARK S, Lee S, Kim Y, Lee Y, et al
    Altered Risk for Cardiovascular Events With Changes in the Metabolic Syndrome Status: A Nationwide Population-Based Study of Approximately 10 Million Persons.
    Ann Intern Med. 2019 Nov 26. pii: 2756142. doi: 10.7326/M19-0563.
    PubMed     Abstract available


  24. SMITH DA
    Review: In dyslipidemia or atherosclerotic CVD, alirocumab and evolocumab vs control each reduce MI and stroke.
    Ann Intern Med. 2019;171:JC56.
    PubMed    


    October 2019
  25. ABSHER JR
    Pooled RCTs: In acute ischemic stroke with salvageable brain tissue, alteplase at 4.5 to 9 hours improved function.
    Ann Intern Med. 2019;171:JC44.
    PubMed    


  26. BELLO NA, Miller EC, Cleary KL, Wapner R, et al
    Cases in Precision Medicine: A Personalized Approach to Stroke and Cardiovascular Risk Assessment in Women.
    Ann Intern Med. 2019 Oct 15. pii: 2753022. doi: 10.7326/M19-1601.
    PubMed     Abstract available


  27. LE MOIGNE E, Jobic Y, Timsit S, Hoffmann C, et al
    Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism.
    Ann Intern Med. 2019;171:527-528.
    PubMed    


  28. KUMAR P, Mojadidi MK, Meier B, Tobis JM, et al
    Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism.
    Ann Intern Med. 2019;171:527.
    PubMed    


    September 2019
  29. GRAHAM J
    After stroke due to ICH while on antithrombotics, starting vs avoiding antiplatelets did not differ for symptomatic ICH.
    Ann Intern Med. 2019;171:JC32.
    PubMed    


    August 2019
  30. HANKEY GJ
    Review: After stroke or TIA, adding clopidogrel to aspirin for </= 1 month reduces recurrence and MACE.
    Ann Intern Med. 2019;171:JC14.
    PubMed    


    July 2019
  31. SANTULLI G
    Catheter ablation did not reduce CV events and mortality more than drug therapy in symptomatic AF.
    Ann Intern Med. 2019;171:JC8.
    PubMed    


  32. KHAN SU, Khan MU, Riaz H, Valavoor S, et al
    Effects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map.
    Ann Intern Med. 2019 Jul 9. pii: 2737825. doi: 10.7326/M19-0341.
    PubMed     Abstract available


    June 2019
  33. KEARON C
    In AF, ABC scores predicted stroke or major bleeding better than CHA2DS2-VASc and HAS-BLED scores, respectively.
    Ann Intern Med. 2019;170:JC71.
    PubMed    


  34. SHAH SJ, Singer DE
    Stroke Rate Variation and Anticoagulation Benefit in Atrial Fibrillation.
    Ann Intern Med. 2019;170:818-819.
    PubMed    


  35. JOOSTEN LPT, van Doorn S, Rutten FH, Geersing GJ, et al
    Stroke Rate Variation and Anticoagulation Benefit in Atrial Fibrillation.
    Ann Intern Med. 2019;170:816-817.
    PubMed    


  36. NARDONE DA
    Stroke Rate Variation and Anticoagulation Benefit in Atrial Fibrillation.
    Ann Intern Med. 2019;170:818.
    PubMed    


  37. REIFFEL JA
    Stroke Rate Variation and Anticoagulation Benefit in Atrial Fibrillation.
    Ann Intern Med. 2019;170:818.
    PubMed    


  38. MAYER M, Alper BS, Leff L
    Stroke Rate Variation and Anticoagulation Benefit in Atrial Fibrillation.
    Ann Intern Med. 2019;170:817-818.
    PubMed    


  39. LIN B, Chung WK
    Cases in Precision Medicine: The Role of Pharmacogenetics in Precision Prescribing.
    Ann Intern Med. 2019;170:796-804.
    PubMed     Abstract available


    May 2019
  40. SCHMIDT MR, Sondergaard L
    Patent Foramen Ovale: A Villain in Pulmonary Embolism?
    Ann Intern Med. 2019 May 7. pii: 2732838. doi: 10.7326/M19-1089.
    PubMed    


    April 2019
  41. UCHINO K
    Guideline: Starting dual antiplatelet therapy </= 24 h after high-risk TIA or minor ischemic stroke is recommended.
    Ann Intern Med. 2019;170:JC38.
    PubMed    


    March 2019
  42. JILLELLA D, Uchino K
    Guideline: 8 professional organizations recommend percutaneous closure of patent foramen ovale in selected patients.
    Ann Intern Med. 2019;170:JC27.
    PubMed    


    February 2019
  43. KAZI DS, Penko J, Coxson PG, Guzman D, et al
    Cost-Effectiveness of Alirocumab: A Just-in-Time Analysis Based on the ODYSSEY Outcomes Trial.
    Ann Intern Med. 2019;170:221-229.
    PubMed     Abstract available


    January 2019
  44. CHAO TF, Chiang CE, Chen TJ, Lip GYH, et al
    Reassessment of Risk for Stroke During Follow-up of Patients With Atrial Fibrillation.
    Ann Intern Med. 2019 Jan 1. pii: 2720037. doi: 10.7326/M18-1177.
    PubMed    


    November 2018
  45. BATES ER
    Review: In coronary artery disease, PCI reduces 30-day and 5-year risk for stroke compared with CABG.
    Ann Intern Med. 2018;169:JC55.
    PubMed    


    October 2018
  46. LOWENSTERN A, Al-Khatib SM, Sharan L, Chatterjee R, et al
    Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic Review.
    Ann Intern Med. 2018 Oct 30. pii: 2711395. doi: 10.7326/M18-1523.
    PubMed     Abstract available


    September 2018

  47. Stroke Rates, Atrial Fibrillation, and Drugs to Prevent Blood Clots.
    Ann Intern Med. 2018 Sep 25. pii: 2703443. doi: 10.7326/P18-0014.
    PubMed    


  48. WRIGHT JM, January CT
    Atrial Fibrillation and Anticoagulation: One Size Fits All?
    Ann Intern Med. 2018 Sep 25. pii: 2703442. doi: 10.7326/M18-2355.
    PubMed    


  49. SHAH SJ, Eckman MH, Aspberg S, Go AS, et al
    Effect of Variation in Published Stroke Rates on the Net Clinical Benefit of Anticoagulation for Atrial Fibrillation.
    Ann Intern Med. 2018 Sep 25. pii: 2703439. doi: 10.7326/M17-2762.
    PubMed     Abstract available


    August 2018
  50. MAI LM, Oczkowski W
    Tenecteplase before thrombectomy for ischemic stroke improved reperfusion compared with alteplase.
    Ann Intern Med. 2018;169:JC20.
    PubMed    


    April 2018
  51. DAMJI O, Lang E
    In perfusion imaging-selected acute ischemic stroke, thrombectomy at 6 to 16 hours improved functional outcomes.
    Ann Intern Med. 2018;168:JC42.
    PubMed    


    March 2018
  52. KUSSMAUL WG 3RD
    Patent Foramen Ovale Closure.
    Ann Intern Med. 2018;168:367-368.
    PubMed    


  53. SHAH R, Nayyar M, Jovin IS, Rashid A, et al
    Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis.
    Ann Intern Med. 2018;168:335-342.
    PubMed     Abstract available


  54. DE ROSA S, Sievert H, Sabatino J, Polimeni A, et al
    Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis.
    Ann Intern Med. 2018;168:343-350.
    PubMed     Abstract available


    February 2018
  55. MAI LM, Oczkowski W
    Late thrombectomy reduced disability in acute stroke with mismatched clinical deficit and infarction volume.
    Ann Intern Med. 2018;168:JC17.
    PubMed    


  56. PATEL T, Patel V
    Review: DOACs reduce intracranial hemorrhage more than warfarin in AF with CKD.
    Ann Intern Med. 2018;168:JC18.
    PubMed    


    January 2018

  57. Adding patent foramen ovale closure to antiplatelet therapy reduced stroke after cryptogenic stroke.
    Ann Intern Med. 2018;168:JC7.
    PubMed    


  58. ALBERTS MJ
    Adding patent foramen ovale closure to antiplatelet drugs reduced ischemic stroke after cryptogenic stroke.
    Ann Intern Med. 2018;168:JC6.
    PubMed    


  59. PARKER S
    Two Doctors Meet.
    Ann Intern Med. 2018;168:160.
    PubMed    


  60. BERKHEMER O, van der Lugt A
    Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke.
    Ann Intern Med. 2018;168:83-84.
    PubMed    


  61. YE F, Zhang Y, Tang R
    Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke.
    Ann Intern Med. 2018;168:82-83.
    PubMed    


  62. MAUS V, Abdullayev N, Psychogios MN, Behme D, et al
    Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke.
    Ann Intern Med. 2018;168:83.
    PubMed    


    December 2017
  63. KOPIN L, Lowenstein C
    Dyslipidemia.
    Ann Intern Med. 2017;167:ITC81-ITC96.
    PubMed     Abstract available


    November 2017
  64. GO AS, Singer DE, Toh S, Cheetham TC, et al
    Outcomes of Dabigatran and Warfarin for Atrial Fibrillation in Contemporary Practice: A Retrospective Cohort Study.
    Ann Intern Med. 2017 Nov 14. doi: 10.7326/M16-1157.
    PubMed     Abstract available


    October 2017
  65. HANKEY GJ
    Pooled RCTs: In symptomatic carotid stenosis, endarterectomy had lower periprocedural risk than stenting.
    Ann Intern Med. 2017;167:JC45.
    PubMed    


  66. SMETANA GW, Schermerhorn M, Mukamal KJ
    Should We Screen This Patient for Carotid Artery Stenosis?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2017;167:484-492.
    PubMed     Abstract available


    September 2017
  67. JACQUIN G, Poppe A
    In acute ischemic stroke, adding early endovascular treatment to usual care improved functional outcomes at 2 y.
    Ann Intern Med. 2017;167:JC29.
    PubMed    


    August 2017
  68. ZHANG H, Plutzky J, Shubina M, Turchin A, et al
    Continued Statin Prescriptions After Adverse Reactions and Patient Outcomes: A Cohort Study.
    Ann Intern Med. 2017;167:221-227.
    PubMed     Abstract available


    June 2017
  69. BERKHEMER OA, Borst J, Kappelhof M, Yoo AJ, et al
    Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke in MR CLEAN.
    Ann Intern Med. 2017;166:867-875.
    PubMed     Abstract available


  70. KRUGER P, Eikelboom J
    Resuming warfarin after intracranial hemorrhage in patients with AF was linked to reduced mortality.
    Ann Intern Med. 2017;166:JC70.
    PubMed    


  71. SPENCER FA, Guyatt GH
    In severe aortic stenosis with intermediate surgical risk, TAVR was noninferior to SAVR for death or disabling stroke.
    Ann Intern Med. 2017;166:JC68.
    PubMed    


    March 2017
  72. QASEEM A, Wilt TJ, Rich R, Humphrey LL, et al
    Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From the American College of Physicians and the American Academy of Family Physicians.
    Ann Intern Med. 2017;166:430-437.
    PubMed     Abstract available


  73. WEISS J, Freeman M, Low A, Fu R, et al
    Benefits and Harms of Intensive Blood Pressure Treatment in Adults Aged 60 Years or Older: A Systematic Review and Meta-analysis.
    Ann Intern Med. 2017;166:419-429.
    PubMed     Abstract available


  74. MEHTA SR
    After PCI with stents for AF, adding rivaroxaban vs warfarin to antiplatelet drugs reduced bleeding.
    Ann Intern Med. 2017;166:JC29.
    PubMed    


  75. BATES ER
    Review: In AF, direct oral anticoagulants reduce all-cause and vascular mortality compared with warfarin.
    Ann Intern Med. 2017;166:JC28.
    PubMed    


    February 2017
  76. BATES ER
    In left main CAD, PCI with everolimus-eluting stents was noninferior to CABG for death, MI, or stroke at 3 years.
    Ann Intern Med. 2017;166:JC21.
    PubMed    


    October 2016
  77. CHUNG M, Tang AM, Fu Z, Wang DD, et al
    Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis.
    Ann Intern Med. 2016 Oct 25. doi: 10.7326/M16-1165.
    PubMed     Abstract available


  78. MCCARTHY L
    Pooled RCTs: In patients with acute ischemic stroke, alteplase increases intracerebral hemorrhage.
    Ann Intern Med. 2016;165:JC42.
    PubMed    


  79. COOK NR, Ridker PM
    Calibration of the Pooled Cohort Equations for Atherosclerotic Cardiovascular Disease: An Update.
    Ann Intern Med. 2016 Oct 11. doi: 10.7326/M16-1739.
    PubMed     Abstract available


    June 2016
  80. WHITLOCK EP, Burda BU, Williams SB, Guirguis-Blake JM, et al
    Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the U.S. Preventive Services Task Force.
    Ann Intern Med. 2016;164:826-35.
    PubMed     Abstract available


  81. HANKEY GJ
    The ABC-stroke risk score was superior to the CHA2DS2-VASc score for predicting stroke in atrial fibrillation.
    Ann Intern Med. 2016;164:JC69.
    PubMed    


    April 2016
  82. DEHMER SP, Maciosek MV, Flottemesch TJ, LaFrance AB, et al
    Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force.
    Ann Intern Med. 2016 Apr 12. doi: 10.7326/M15-2129.
    PubMed     Abstract available


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