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Tuberculosis

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 54 articles: HTML format

Single Articles

March 2020
1. OYAS O, Borrell S, Trauner A, Zimmermann M, et al
   Model-based integration of genomics and metabolomics reveals SNP functionality in Mycobacterium tuberculosis.
   Proc Natl Acad Sci U S A. 2020 Mar 30. pii: 1915551117.
   PubMed     Abstract available
   
   
   
2. RAHMAN MA, Cumming BM, Addicott KW, Pacl HT, et al
   Hydrogen sulfide dysregulates the immune response by suppressing central carbon metabolism to promote tuberculosis.
   Proc Natl Acad Sci U S A. 2020 Mar 5. pii: 1919211117.
   PubMed     Abstract available
   
   
   
3. VAHIDI S, Ripstein ZA, Juravsky JB, Rennella E, et al
   An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
   Proc Natl Acad Sci U S A. 2020 Mar 2. pii: 1921630117.
   PubMed     Abstract available
   
   
   February 2020
4. VARGAS R JR, Farhat MR
   Antibiotic treatment and selection for glpK mutations in patients with active tuberculosis disease.
   Proc Natl Acad Sci U S A. 2020 Feb 19. pii: 1920788117.
   PubMed    
   
   
   
5. SAFI H, Sherman DR, Dick T, Alland D, et al
   Reply to Vargas and Farhat: Mycobacterium tuberculosis glpK mutants in human tuberculosis.
   Proc Natl Acad Sci U S A. 2020 Feb 19. pii: 1922199117.
   PubMed    
   
   
   January 2020
6. LIENARD J, Nobs E, Lovins V, Movert E, et al
   The Mycobacterium marinum ESX-1 system mediates phagosomal permeabilization and type I interferon production via separable mechanisms.
   Proc Natl Acad Sci U S A. 2020;117:1160-1166.
   PubMed     Abstract available
   
   
   November 2019
7. GAWRISCH K
   Mycobacterium tuberculosis enters macrophages with aid from a bacterial lipid.
   Proc Natl Acad Sci U S A. 2019 Nov 22. pii: 1918900116.
   PubMed    
   
   
   
8. AUGENSTREICH J, Haanappel E, Ferre G, Czaplicki G, et al
   The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages.
   Proc Natl Acad Sci U S A. 2019 Nov 22. pii: 1910368116.
   PubMed     Abstract available
   
   
   October 2019
9. CASSIDY R, Manski CF
   Tuberculosis diagnosis and treatment under uncertainty.
   Proc Natl Acad Sci U S A. 2019 Oct 29. pii: 1912091116.
   PubMed     Abstract available
   
   
   
10. BROWN TS, Challagundla L, Baugh EH, Omar SV, et al
    Pre-detection history of extensively drug-resistant tuberculosis in KwaZulu-Natal, South Africa.
    Proc Natl Acad Sci U S A. 2019 Oct 28. pii: 1906636116.
    PubMed     Abstract available
    
    
    September 2019
11. WANG Z, Soni V, Marriner G, Kaneko T, et al
    Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline.
    Proc Natl Acad Sci U S A. 2019 Sep 9. pii: 1907946116.
    PubMed     Abstract available
    
    
    
12. SAFI H, Gopal P, Lingaraju S, Ma S, et al
    Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance.
    Proc Natl Acad Sci U S A. 2019 Sep 5. pii: 1907631116.
    PubMed     Abstract available
    
    
    July 2019
13. HEINKEL F, Abraham L, Ko M, Chao J, et al
    Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2019 Jul 31. pii: 1820683116.
    PubMed     Abstract available
    
    
    
14. WANG H, Fedorov AA, Fedorov EV, Hunt DM, et al
    An essential bifunctional enzyme in Mycobacterium tuberculosis for itaconate dissimilation and leucine catabolism.
    Proc Natl Acad Sci U S A. 2019 Jul 18. pii: 1906606116.
    PubMed     Abstract available
    
    
    
15. BEECHLER BR, Boersma KS, Buss PE, Coon CAC, et al
    Bovine tuberculosis disturbs parasite functional trait composition in African buffalo.
    Proc Natl Acad Sci U S A. 2019 Jul 1. pii: 1903674116.
    PubMed     Abstract available
    
    
    June 2019
16. ZHU DX, Garner AL, Galburt EA, Stallings CL, et al
    CarD contributes to diverse gene expression outcomes throughout the genome of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2019 Jun 19. pii: 1900176116.
    PubMed     Abstract available
    
    
    
17. CARCAMO-NORIEGA EN, Sathyamoorthi S, Banerjee S, Gnanamani E, et al
    1,4-Benzoquinone antimicrobial agents against Staphylococcus aureus and Mycobacterium tuberculosis derived from scorpion venom.
    Proc Natl Acad Sci U S A. 2019 Jun 10. pii: 1812334116.
    PubMed     Abstract available
    
    
    May 2019
18. KERNER G, Ramirez-Alejo N, Seeleuthner Y, Yang R, et al
    Homozygosity for TYK2 P1104A underlies tuberculosis in about 1% of patients in a cohort of European ancestry.
    Proc Natl Acad Sci U S A. 2019 May 8. pii: 1903561116.
    PubMed     Abstract available
    
    
    
19. FLENTIE K, Harrison GA, Tukenmez H, Livny J, et al
    Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2019 May 6. pii: 1818009116.
    PubMed     Abstract available
    
    
    April 2019
20. PACIS A, Mailhot-Leonard F, Tailleux L, Randolph HE, et al
    Gene activation precedes DNA demethylation in response to infection in human dendritic cells.
    Proc Natl Acad Sci U S A. 2019;116:6938-6943.
    PubMed     Abstract available
    
    
    March 2019
21. SHEN L, Frencher J, Huang D, Wang W, et al
    Immunization of Vgamma2Vdelta2 T cells programs sustained effector memory responses that control tuberculosis in nonhuman primates.
    Proc Natl Acad Sci U S A. 2019 Mar 8. pii: 1811380116.
    PubMed     Abstract available
    
    
    
22. ZHANG AT, Montgomery MG, Leslie AGW, Cook GM, et al
    The structure of the catalytic domain of the ATP synthase from Mycobacterium smegmatis is a target for developing antitubercular drugs.
    Proc Natl Acad Sci U S A. 2019;116:4206-4211.
    PubMed     Abstract available
    
    
    February 2019
23. DUNCAN TM
    Turbine enzyme's structure in the crosshairs to target tuberculosis.
    Proc Natl Acad Sci U S A. 2019 Feb 19. pii: 1900798116.
    PubMed    
    
    
    
24. BECKER SH, Jastrab JB, Dhabaria A, Chaton CT, et al
    The Mycobacterium tuberculosis Pup-proteasome system regulates nitrate metabolism through an essential protein quality control pathway.
    Proc Natl Acad Sci U S A. 2019 Feb 5. pii: 1819468116.
    PubMed     Abstract available
    
    
    December 2018
25. FURUSE Y
    Analysis of research intensity on infectious disease by disease burden reveals which infectious diseases are neglected by researchers.
    Proc Natl Acad Sci U S A. 2018 Dec 31. pii: 1814484116.
    PubMed     Abstract available
    
    
    September 2018
26. YU H, Lupoli TJ, Kovach A, Meng X, et al
    ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB.
    Proc Natl Acad Sci U S A. 2018 Sep 26. pii: 1810648115.
    PubMed     Abstract available
    
    
    
27. MIZRAHI V, Warner DF
    Death of Mycobacterium tuberculosis by l-arginine starvation.
    Proc Natl Acad Sci U S A. 2018 Sep 6. pii: 1813587115.
    PubMed    
    
    
    August 2018
28. TIWARI S, van Tonder AJ, Vilcheze C, Mendes V, et al
    Arginine-deprivation-induced oxidative damage sterilizes Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2018 Aug 24. pii: 1808874115.
    PubMed     Abstract available
    
    
    
29. LI Y, Sharma MR, Koripella RK, Yang Y, et al
    Zinc depletion induces ribosome hibernation in mycobacteria.
    Proc Natl Acad Sci U S A. 2018;115:8191-8196.
    PubMed     Abstract available
    
    
    July 2018
30. GORSICH EE, Etienne RS, Medlock J, Beechler BR, et al
    Opposite outcomes of coinfection at individual and population scales.
    Proc Natl Acad Sci U S A. 2018;115:7545-7550.
    PubMed     Abstract available
    
    
    June 2018
31. GERRICK ER, Barbier T, Chase MR, Xu R, et al
    Small RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response.
    Proc Natl Acad Sci U S A. 2018 Jun 5. pii: 1718003115.
    PubMed     Abstract available
    
    
    May 2018
32. HODGES HL, Brown RA, Crooks JA, Weibel DB, et al
    Imaging mycobacterial growth and division with a fluorogenic probe.
    Proc Natl Acad Sci U S A. 2018;115:5271-5276.
    PubMed     Abstract available
    
    
    March 2018
33. CROWE AM, Workman SD, Watanabe N, Worrall LJ, et al
    IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.
    Proc Natl Acad Sci U S A. 2018 Mar 26. pii: 1717015115.
    PubMed     Abstract available
    
    
    
34. ARREGUI S, Iglesias MJ, Samper S, Marinova D, et al
    Data-driven model for the assessment of Mycobacterium tuberculosis transmission in evolving demographic structures.
    Proc Natl Acad Sci U S A. 2018 Mar 21. pii: 1720606115.
    PubMed     Abstract available
    
    
    January 2018
35. VILCHEZE C, Weinrick B, Leung LW, Jacobs WR Jr., et al
    Plasticity of Mycobacterium tuberculosis NADH dehydrogenases and their role in virulence.
    Proc Natl Acad Sci U S A. 2018 Jan 30. pii: 1721545115.
    PubMed     Abstract available
    
    
    
36. ESMAIL H, Lai RP, Lesosky M, Wilkinson KA, et al
    Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis.
    Proc Natl Acad Sci U S A. 2018 Jan 16. pii: 1711853115.
    PubMed     Abstract available
    
    
    December 2017
37. GAUTAM US, Foreman TW, Bucsan AN, Veatch AV, et al
    In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Dec 18. pii: 1711373114.
    PubMed     Abstract available
    
    
    November 2017
38. CHANCELLOR A, Tocheva AS, Cave-Ayland C, Tezera L, et al
    CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains.
    Proc Natl Acad Sci U S A. 2017 Nov 20. pii: 201708252.
    PubMed     Abstract available
    
    
    October 2017
39. 
    Correction for Koster et al., Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.
    Proc Natl Acad Sci U S A. 2017 Oct 30. pii: 201718266.
    PubMed    
    
    
    
40. BLANC L, Gilleron M, Prandi J, Song OR, et al
    Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids.
    Proc Natl Acad Sci U S A. 2017 Oct 2. pii: 201707840.
    PubMed     Abstract available
    
    
    September 2017
41. KOSTER S, Upadhyay S, Chandra P, Papavinasasundaram K, et al
    Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.
    Proc Natl Acad Sci U S A. 2017 Sep 27. pii: 201707792.
    PubMed     Abstract available
    
    
    July 2017
42. PHAM TV, Murkin AS, Moynihan MM, Harris L, et al
    Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Jul 5. pii: 201706134.
    PubMed     Abstract available
    
    
    June 2017
43. KALIA NP, Hasenoehrl EJ, Ab Rahman NB, Koh VH, et al
    Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
    Proc Natl Acad Sci U S A. 2017 Jun 26. pii: 201706139.
    PubMed     Abstract available
    
    
    May 2017
44. SAITO K, Warrier T, Somersan-Karakaya S, Kaminski L, et al
    Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
    Proc Natl Acad Sci U S A. 2017 May 30. pii: 201705385.
    PubMed     Abstract available
    
    
    April 2017
45. LI H, Wang XX, Wang B, Fu L, et al
    Latently and uninfected healthcare workers exposed to TB make protective antibodies against Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Apr 24. pii: 201611776.
    PubMed     Abstract available
    
    
    
46. VILCHEZE C, Hartman T, Weinrick B, Jain P, et al
    Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Apr 10. pii: 201704376.
    PubMed     Abstract available
    
    
    March 2017
47. LIU C, Zhao Z, Fan J, Lyon CJ, et al
    Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring.
    Proc Natl Acad Sci U S A. 2017 Mar 27. pii: 201621360.
    PubMed     Abstract available
    
    
    
48. PUCKETT S, Trujillo C, Wang Z, Eoh H, et al
    Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Mar 6. pii: 201617655.
    PubMed     Abstract available
    
    
    January 2017
49. TROEGELER A, Mercier I, Cougoule C, Pietretti D, et al
    C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells.
    Proc Natl Acad Sci U S A. 2017 Jan 9. pii: 201613254.
    PubMed     Abstract available
    
    
    November 2016
50. ELDHOLM V, Pettersson JH, Brynildsrud OB, Kitchen A, et al
    Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201611283.
    PubMed     Abstract available
    
    
    
51. LUPOLI TJ, Fay A, Adura C, Glickman MS, et al
    Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.
    Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201617644.
    PubMed     Abstract available
    
    
    
52. SOUTTER HH, Centrella P, Clark MA, Cuozzo JW, et al
    Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.
    Proc Natl Acad Sci U S A. 2016 Nov 18. pii: 201610978.
    PubMed     Abstract available
    
    
    September 2016
53. ROTHCHILD AC, Sissons JR, Shafiani S, Plaisier C, et al
    MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2016 Sep 28. pii: 201608255.
    PubMed     Abstract available
    
    
    April 2016
54. MATSUI T, Nambu S, Goulding CW, Takahashi S, et al
    Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation.
    Proc Natl Acad Sci U S A. 2016;113:3779-84.
    PubMed     Abstract available
    
    

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