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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 35 articles:
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Single Articles


    May 2026
  1. COHEN BLM, Croke K, Hanage WP, Cohen T, et al
    Migration-linked TB epidemics: How TB elimination in high-income countries depends on the success of TB control in high-burden settings.
    Proc Natl Acad Sci U S A. 2026;123:e2611864123.
    PubMed     Abstract available


    March 2026
  2. DODD PJ, Horton KC
    A global analysis of patterns of tuberculosis exposure and transmission.
    Proc Natl Acad Sci U S A. 2026;123:e2526321123.
    PubMed     Abstract available


    January 2026
  3. MCDONOUGH LD, Li S, Munsamy-Govender V, Gwin CM, et al
    An activator of a two-component system controls cell separation and intrinsic drug resistance in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2026;123:e2519608123.
    PubMed     Abstract available


    December 2025
  4. TRAN PM, Anaya-Sanchez A, Ji DX, Schwarz MCR, et al
    Cell envelope maintenance by PhoP is essential for Mycobacterium tuberculosis methylglyoxal resistance.
    Proc Natl Acad Sci U S A. 2025;122:e2523024122.
    PubMed     Abstract available


    October 2025
  5. DANCHUK SN, Duffy SC, Sullivan J, Beenish Rufai S, et al
    Virulence hierarchies within the Mycobacterium tuberculosis complex.
    Proc Natl Acad Sci U S A. 2025;122:e2507104122.
    PubMed     Abstract available


    September 2025
  6. FOUNTAIN AJ, Bohning J, McLaughlin SH, Morgan TE, et al
    Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages increased bedaquiline resistance.
    Proc Natl Acad Sci U S A. 2025;122:e2516660122.
    PubMed     Abstract available


  7. LE MOUELLIC W, Levillain F, Wu TD, Caouaille M, et al
    Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance.
    Proc Natl Acad Sci U S A. 2025;122:e2503966122.
    PubMed     Abstract available


  8. KOLESKE B, Rajagopalan S, Schill C, Lun S, et al
    Loss of the ESX-5 secretion locus in Mycobacterium tuberculosis reshapes the mycomembrane and enhances ESX-1 substrate secretion.
    Proc Natl Acad Sci U S A. 2025;122:e2509997122.
    PubMed     Abstract available


  9. WANG ER, Cho K, Harrison GA, Smelyansky SR, et al
    Metabolic rewiring of isoniazid sensitivity in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2025;122:e2421336122.
    PubMed     Abstract available


    July 2025
  10. CHAUHAN K, Datta D, Kapoor Y, Passricha N, et al
    A Mycobacterium tuberculosis secreted virulence factor Rv1435c/hsr1 disrupts host snRNP biogenesis.
    Proc Natl Acad Sci U S A. 2025;122:e2423349122.
    PubMed     Abstract available


    May 2025
  11. SANTAMARIA C, Biegas KJ, Lim PN, Cabral J, et al
    Trehalose dimycolate inhibits phagosome maturation and promotes intracellular M. tuberculosis growth via noncanonical SNARE interactions.
    Proc Natl Acad Sci U S A. 2025;122:e2423292122.
    PubMed     Abstract available


    April 2025
  12. FOUNTAIN AJ, Waller NJE, Cheung CY, Jowsey W, et al
    Verapamil and its metabolite norverapamil inhibit the Mycobacterium tuberculosis MmpS5L5 efflux pump to increase bedaquiline activity.
    Proc Natl Acad Sci U S A. 2025;122:e2426827122.
    PubMed     Abstract available



  13. Correction for Quach et al., Deep learning-driven bacterial cytological profiling to determine antimicrobial mechanisms in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2025;122:e2504475122.
    PubMed    


    March 2025
  14. YANG Z, Zhang L, Ottavi S, Geri JB, et al
    ACOD1-mediated lysosomal membrane permeabilization contributes to Mycobacterium tuberculosis-induced macrophage death.
    Proc Natl Acad Sci U S A. 2025;122:e2425309122.
    PubMed     Abstract available


  15. MISHRA S, Singh PR, Hu X, Lopez-Quezada L, et al
    Candidate transmission survival genome of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2025;122:e2425981122.
    PubMed     Abstract available


  16. SAHA S, Roy S, Hazra A, Das D, et al
    S-nitrosylation-triggered secretion of mycobacterial PknG leads to phosphorylation of SODD to prevent apoptosis of infected macrophages.
    Proc Natl Acad Sci U S A. 2025;122:e2404106122.
    PubMed     Abstract available


  17. OLUOCH PO, Koh EI, Proulx MK, Reames CJ, et al
    Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection.
    Proc Natl Acad Sci U S A. 2025;122:e2417525122.
    PubMed     Abstract available


    February 2025
  18. LU Z, Zhang Y, Zhong Y, Qiang L, et al
    A bacterial effector manipulates host lysosomal protease activity-dependent plasticity in cell death modalities to facilitate infection.
    Proc Natl Acad Sci U S A. 2025;122:e2406715122.
    PubMed     Abstract available


  19. QUACH D, Sharp M, Ahmed S, Ames L, et al
    Deep learning-driven bacterial cytological profiling to determine antimicrobial mechanisms in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2025;122:e2419813122.
    PubMed     Abstract available


    January 2025
  20. PRIYA M, Gupta SK, Koundal A, Kapoor S, et al
    Itaconate mechanism of action and dissimilation in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2025;122:e2423114122.
    PubMed     Abstract available


    December 2024
  21. KAHNE SC, Yoo JH, Chen J, Nakedi K, et al
    Identification of a depupylation regulator for an essential enzyme in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2024;121:e2407239121.
    PubMed     Abstract available


    October 2024
  22. LI D, Zhang X, Yao Y, Sun X, et al
    Structure and function of Mycobacterium tuberculosis EfpA as a lipid transporter and its inhibition by BRD-8000.3.
    Proc Natl Acad Sci U S A. 2024;121:e2412653121.
    PubMed     Abstract available


  23. ABHIMANYU, Longlax SC, Nishiguchi T, Ladki M, et al
    TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance.
    Proc Natl Acad Sci U S A. 2024;121:e2404841121.
    PubMed     Abstract available


    July 2024

  24. Correction for Rengarajan et al., Mycobacterium tuberculosis Rv2224c modulates innate immune responses.
    Proc Natl Acad Sci U S A. 2024;121:e2410437121.
    PubMed    


    June 2024
  25. OGUNLADE B, Tadesse LF, Li H, Vu N, et al
    Rapid, antibiotic incubation-free determination of tuberculosis drug resistance using machine learning and Raman spectroscopy.
    Proc Natl Acad Sci U S A. 2024;121:e2315670121.
    PubMed     Abstract available


  26. COHEN SB, Urdahl KB
    Weaponizing the bystander T cell army to fight tuberculosis.
    Proc Natl Acad Sci U S A. 2024;121:e2407559121.
    PubMed    


    May 2024
  27. PATERSON RL, La Manna MP, Arena De Souza V, Walker A, et al
    An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2024;121:e2318003121.
    PubMed     Abstract available


    April 2024
  28. DATTA M, Via LE, Dartois V, Weiner DM, et al
    Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits.
    Proc Natl Acad Sci U S A. 2024;121:e2321336121.
    PubMed     Abstract available


  29. FORTUNE SM
    The Titanic question in TB control: Should we worry about the bummock?
    Proc Natl Acad Sci U S A. 2024;121:e2403321121.
    PubMed    


    March 2024
  30. PATTERSON B, Dinkele R, Gessner S, Koch A, et al
    Aerosolization of viable Mycobacterium tuberculosis bacilli by tuberculosis clinic attendees independent of sputum-Xpert Ultra status.
    Proc Natl Acad Sci U S A. 2024;121:e2314813121.
    PubMed     Abstract available


    January 2024
  31. CHUGH S, Tiwari P, Suri C, Gupta SK, et al
    Polyphosphate kinase-1 regulates bacterial and host metabolic pathways involved in pathogenesis of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2024;121:e2309664121.
    PubMed     Abstract available


    November 2023
  32. HORTON KC, Richards AS, Emery JC, Esmail H, et al
    Reevaluating progression and pathways following Mycobacterium tuberculosis infection within the spectrum of tuberculosis.
    Proc Natl Acad Sci U S A. 2023;120:e2221186120.
    PubMed     Abstract available


    August 2023
  33. LIANG J, Liu F, Xu P, Shangguan W, et al
    Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC.
    Proc Natl Acad Sci U S A. 2023;120:e2307625120.
    PubMed     Abstract available


    July 2023
  34. VARGAS R JR, Luna MJ, Freschi L, Marin M, et al
    Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex.
    Proc Natl Acad Sci U S A. 2023;120:e2301394120.
    PubMed     Abstract available


    June 2023
  35. GONG Y, Wei C, Wang J, Mu N, et al
    Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2023;120:e2302858120.
    PubMed     Abstract available


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