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  Colorectal Neoplasms

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Articles published in Cancer Lett

Retrieve available abstracts of 66 articles:
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Single Articles


    August 2025
  1. SUN Z, Wu R, Liang X, Shi T, et al
    MLCK inhibition induces synthetic lethality in MYC-driven cancer.
    Cancer Lett. 2025;625:217803.
    PubMed     Abstract available


    July 2025
  2. BIRGERSSON M, Holm M, Gallardo-Dodd CJ, Chen B, et al
    Intestinal estrogen receptor beta modulates the murine colon tumor immune microenvironment.
    Cancer Lett. 2025;622:217661.
    PubMed     Abstract available


  3. DANEK V, Tureckova J, Huebner K, Erlenbach-Wuensch K, et al
    CUL4A exhibits tumor-suppressing role via regulation of HUWE1-mediated SMAD3 intracellular shuttling.
    Cancer Lett. 2025;621:217663.
    PubMed     Abstract available


    June 2025
  4. GERAKOPOULOS V, Ramos C, Muller C, Walterskirchen N, et al
    Single-cell transcriptomic analysis identifies tissue-specific fibroblasts as the main modulators of myeloid cells in peritoneal metastasis of different origin.
    Cancer Lett. 2025;620:217678.
    PubMed     Abstract available


  5. KHAN S, Karmokar A, Howells L, Britton RG, et al
    An old spice with new tricks: Curcumin targets adenoma and colorectal cancer stem-like cells associated with poor survival outcomes.
    Cancer Lett. 2025 Jun 19:217885. doi: 10.1016/j.canlet.2025.217885.
    PubMed     Abstract available


  6. YU C, Lu W, Wu J, Fang X, et al
    Liver metastasis or peritoneal metastasis: single-cell RNA sequencing reveals the organotropism in colorectal cancer is driven by distinct partial-EMT processes.
    Cancer Lett. 2025 Jun 17:217880. doi: 10.1016/j.canlet.2025.217880.
    PubMed     Abstract available


    May 2025
  7. MIDDE A, Arri N, Kristian T, Mukherjee S, et al
    Corrigendum to "Targeting mitochondrial ribosomal protein expression by andrographolide and melatonin for colon cancer treatment" [Cancer Lett. 619 (2025) 1-11 217647].
    Cancer Lett. 2025 May 30:217784. doi: 10.1016/j.canlet.2025.217784.
    PubMed    


  8. ZHOU M, Guan B, Liu Y, Gu Q, et al
    Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles shapes an immunosuppressive microenvironment in colorectal liver metastases by promoting tumor stemness and neutrophil extracellular traps formation.
    Cancer Lett. 2025;618:217642.
    PubMed     Abstract available


  9. SUN Y, Lu J, Tung Lau EY, Zeng Y, et al
    Fusobacterium nucleatum enhances cholesterol biosynthesis in colorectal cancer via miR-130a-3p-mediated AMPK inhibition, a process counteracted by butyrate.
    Cancer Lett. 2025 May 23:217810. doi: 10.1016/j.canlet.2025.217810.
    PubMed     Abstract available


  10. CHEN X, Cao Y, Zhao Y, Ma Y, et al
    Neurodegeneration of local sympathetic inputs promotes colorectal cancer progression.
    Cancer Lett. 2025;625:217817.
    PubMed     Abstract available


  11. HU D, Zhao J, Wu M, Zhou Y, et al
    Microbial Interactions Induce the Mutational Signature of Mismatch Repair Deficiency in Colorectal Cancer and Associated with EPPK1 Mutations.
    Cancer Lett. 2025 May 16:217807. doi: 10.1016/j.canlet.2025.217807.
    PubMed     Abstract available


  12. HE K, Wang H, Wu H, Li W, et al
    Activated Schwann cells promote tumor growth in colon cancer.
    Cancer Lett. 2025;626:217791.
    PubMed     Abstract available


  13. LU YX, Ju HQ, Wang F, Chen LZ, et al
    Corrigendum to "Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis" [Cancer Lett. 380 (2016) 87-97].
    Cancer Lett. 2025;625:217756.
    PubMed    


  14. STRIPPOLI R
    Colorectal cancer peritoneal metastasis is promoted by tissue-specific fibroblasts that can arise in response to various local disorders.
    Cancer Lett. 2025;625:217749.
    PubMed    


  15. ZHOU XY, Zhang NC, Zhang XN, Sun XD, et al
    The carcinogenic metabolite acetaldehyde impairs cGAS activity to negatively regulate antiviral and antitumor immunity.
    Cancer Lett. 2025;617:217615.
    PubMed     Abstract available


    April 2025
  16. ZHONG YX, Zhao HB, Lian MH, Shen JM, et al
    SUMOylated hnRNPM suppresses PFKFB3 phosphorylation to regulate glycolysis and tumorigenesis.
    Cancer Lett. 2025;616:217573.
    PubMed     Abstract available


  17. RAMOS C, Walterskirchen N, Knobl V, Zotter C, et al
    Colorectal cancer peritoneal metastasis is promoted by tissue-specific fibroblasts that can arise in response to various local disorders.
    Cancer Lett. 2025 Apr 12:217686. doi: 10.1016/j.canlet.2025.217686.
    PubMed     Abstract available


  18. HOLDFELDT A, Salerno S, Stahlberg A, Lindskog EB, et al
    The colorectal cancer microenvironment governs clinical behaviors and chemotherapy response.
    Cancer Lett. 2025 Apr 1:217687. doi: 10.1016/j.canlet.2025.217687.
    PubMed    


    March 2025
  19. RICHIARDONE E, Giolito MV, Al Roumi R, Ambroise J, et al
    Acidosis overrides molecular heterogeneity to shape therapeutically targetable metabolic phenotypes in colon cancers.
    Cancer Lett. 2025;613:217512.
    PubMed     Abstract available


  20. GU Y, Ye Q, Huang X, Cao Y, et al
    Glycosaminoglycan modification of NRP1 exon 4-skipping variant drives colorectal cancer metastasis via endosomal-exosomal trafficking.
    Cancer Lett. 2025 Mar 27:217683. doi: 10.1016/j.canlet.2025.217683.
    PubMed     Abstract available


  21. MIDDE A, Arri N, Kristian T, Mukherjee S, et al
    Targeting mitochondrial ribosomal protein expression by andrographolide and melatonin for colon cancer treatment.
    Cancer Lett. 2025;619:217647.
    PubMed     Abstract available


  22. LI M, Gao X, Lin X, Zhang Y, et al
    Analysis of germline-somatic mutational connections in colorectal cancer reveals differential tumorigenic patterns and a novel predictive marker for germline mutation carriers.
    Cancer Lett. 2025 Mar 19:217637. doi: 10.1016/j.canlet.2025.217637.
    PubMed     Abstract available


  23. GUO Z, He L, Wang W, Tian S, et al
    FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway.
    Cancer Lett. 2025 Mar 18:217643. doi: 10.1016/j.canlet.2025.217643.
    PubMed     Abstract available


  24. YAO L, Yin H, Yang C, Han S, et al
    GENERATING RESEARCH HYPOTHESES TO OVERCOME KEY CHALLENGES IN THE EARLY DIAGNOSIS OF COLORECTAL CANCER - FUTURE APPLICATION OF AI.
    Cancer Lett. 2025 Mar 15:217632. doi: 10.1016/j.canlet.2025.217632.
    PubMed     Abstract available


    February 2025
  25. LOPES AL, Paulino AC, Thaumaturgo MAS, Araujo WM, et al
    Dietary intake of the red meat-derived glycan Neu5Gc fuels colorectal cancer through up-regulation of Wnt signaling pathway.
    Cancer Lett. 2025;616:217598.
    PubMed     Abstract available


  26. BAI M, Jin Y, Jin Z, Xie Y, et al
    Distinct Immunophenotypic Profiles and Neutrophil Heterogeneity in Colorectal Cancer.
    Cancer Lett. 2025 Feb 22:217570. doi: 10.1016/j.canlet.2025.217570.
    PubMed     Abstract available


  27. WANG T, Weng M, Li K, Li G, et al
    LIN28B enhances the chemosensitivity of colon cancer cells via inducing genomic instability by upsetting the balance between the production and removal of reactive oxygen species.
    Cancer Lett. 2025 Feb 20:217572. doi: 10.1016/j.canlet.2025.217572.
    PubMed     Abstract available


  28. ZHUO FF, Li L, Liu TT, Liang XM, et al
    Corrigendum to "Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells" [Canc. Lett. 573 (2023) 216364].
    Cancer Lett. 2025 Feb 9:217533. doi: 10.1016/j.canlet.2025.217533.
    PubMed    


    January 2025
  29. BAI X, Liu B, Fan D, Lu Y, et al
    Modulating the gut microbiota: A novel perspective in colorectal cancer treatment.
    Cancer Lett. 2025 Jan 11:217459. doi: 10.1016/j.canlet.2025.217459.
    PubMed     Abstract available


  30. ZHAN Y, Sun D, Gao J, Gao Q, et al
    Single-cell Transcriptomics Reveals Intratumor Heterogeneity and the Potential Roles of Cancer Stem Cells and myCAFs in Colorectal Cancer Liver Metastasis and Recurrence.
    Cancer Lett. 2025 Jan 11:217452. doi: 10.1016/j.canlet.2025.217452.
    PubMed     Abstract available


    December 2024
  31. XU C, Jiang C, Tian Y, Liu Y, et al
    Nervous system in colorectal cancer.
    Cancer Lett. 2024 Dec 24:217431. doi: 10.1016/j.canlet.2024.217431.
    PubMed     Abstract available


  32. ZHOU Y, Lei T, Tang Z, Guo P, et al
    Increased phosphorylation of AMPKalpha1 S485 in colorectal cancer and identification of PKCalpha as a responsible kinase.
    Cancer Lett. 2024 Dec 24:217418. doi: 10.1016/j.canlet.2024.217418.
    PubMed     Abstract available


  33. MALIER M, Laverriere MH, Henry M, Yakoubi M, et al
    Tumor-associated macrophages confer resistance to chemotherapy (Trifluridine/Tipiracil) in digestive cancers by overexpressing thymidine phosphorylase.
    Cancer Lett. 2024;606:217307.
    PubMed     Abstract available


    November 2024
  34. DONG Z, Ojha A, Barlow L, Luo L, et al
    The eIF3a translational control axis in the Wnt/beta-catenin signaling pathway and colon tumorigenesis.
    Cancer Lett. 2024;605:217303.
    PubMed     Abstract available


  35. O'BRIEN RM, Meltzer S, Buckley CE, Heeran AB, et al
    Complement is increased in treatment resistant rectal cancer and modulates radioresistance.
    Cancer Lett. 2024;604:217253.
    PubMed     Abstract available


  36. YAO B, Wu J
    Letter to the editor on 'A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer'.
    Cancer Lett. 2024;604:217212.
    PubMed    


    September 2024
  37. TAN YT, Li T, Wang RB, Liu ZK, et al
    WTAP weakens oxaliplatin chemosensitivity of colorectal cancer by preventing PANoptosis.
    Cancer Lett. 2024;604:217254.
    PubMed     Abstract available


  38. YANG H, Gong C, Wu Y, Xie X, et al
    LncRNA SNHG1 facilitates colorectal cancer cells metastasis by recruiting HNRNPD protein to stabilize SERPINA3 mRNA.
    Cancer Lett. 2024 Sep 2:217217. doi: 10.1016/j.canlet.2024.217217.
    PubMed     Abstract available


    August 2024
  39. LI M, Xie Y, Zhang J, Zhou X, et al
    Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects.
    Cancer Lett. 2024;598:217111.
    PubMed     Abstract available


  40. ZHOU L, Wen R, Bai C, Li Z, et al
    Spatial transcriptomic revealed intratumor heterogeneity and cancer stem cell enrichment in colorectal cancer metastasis.
    Cancer Lett. 2024 Aug 17:217181. doi: 10.1016/j.canlet.2024.217181.
    PubMed     Abstract available


  41. HAN Y, Pu Y, Liu X, Liu Z, et al
    YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in a m6A-dependent manner.
    Cancer Lett. 2024 Aug 14:217186. doi: 10.1016/j.canlet.2024.217186.
    PubMed     Abstract available


  42. LING T, Dai Z, Wang H, Kien TT, et al
    Serotonylation in tumor-associated fibroblasts contributes to the tumor-promoting roles of serotonin in colorectal cancer.
    Cancer Lett. 2024 Aug 1:217150. doi: 10.1016/j.canlet.2024.217150.
    PubMed     Abstract available


    July 2024
  43. KONG WS, Li JJ, Deng YQ, Ju HQ, et al
    Immunomodulatory molecules in colorectal cancer liver metastasis.
    Cancer Lett. 2024;598:217113.
    PubMed     Abstract available


  44. ZHU N, Ding Y, Mi M, Yang J, et al
    Loss-of-function mutation of REV1 (p.R704Q) mediates cetuximab primary resistance by activating autophagy in RAS-wild type metastatic colorectal cancer.
    Cancer Lett. 2024 Jul 3:217103. doi: 10.1016/j.canlet.2024.217103.
    PubMed     Abstract available


  45. LUO XJ, Lu YX, Wang Y, Huang R, et al
    M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP1.
    Cancer Lett. 2024 Jul 2:217085. doi: 10.1016/j.canlet.2024.217085.
    PubMed     Abstract available


  46. RICHIARDONE E, Al Roumi R, Lardinois F, Giolito MV, et al
    MCT1-dependent lactate recycling is a metabolic vulnerability in colorectal cancer cells upon acquired resistance to anti-EGFR targeted therapy.
    Cancer Lett. 2024 Jul 2:217091. doi: 10.1016/j.canlet.2024.217091.
    PubMed     Abstract available


  47. CHEN Q, Chen J, Deng Y, Bi X, et al
    Personalized prediction of postoperative complication and survival among Colorectal Liver Metastases Patients Receiving Simultaneous Resection using machine learning approaches: A multi-center study.
    Cancer Lett. 2024;593:216967.
    PubMed     Abstract available


  48. HUANG C, Tan H, Wang J, Huang L, et al
    beta-hydroxybutyrate restrains colitis-associated tumorigenesis by inhibiting HIF-1alpha-mediated angiogenesis.
    Cancer Lett. 2024;593:216940.
    PubMed     Abstract available


    June 2024
  49. HANG D, Sun D, Du L, Huang J, et al
    Development and evaluation of a risk prediction tool for risk-adapted screening of colorectal cancer in China.
    Cancer Lett. 2024;597:217057.
    PubMed     Abstract available


  50. YUAN M, Zhang C, Chen S, Ye S, et al
    PDP1 promotes KRAS mutant colorectal cancer progression by serving as a scaffold for BRAF and MEK1.
    Cancer Lett. 2024;597:217007.
    PubMed     Abstract available


  51. BIAN Y, Xu S, Gao Z, Ding J, et al
    m(6)A modification of lncRNA ABHD11-AS1 promotes colorectal cancer progression and inhibits ferroptosis through TRIM21/IGF2BP2/ FOXM1 positive feedback loop.
    Cancer Lett. 2024 Jun 3:217004. doi: 10.1016/j.canlet.2024.217004.
    PubMed     Abstract available


    May 2024
  52. AGORKU DJ, Bosio A, Alves F, Strobel P, et al
    Colorectal cancer-associated fibroblasts inhibit effector T cells via NECTIN2 signaling.
    Cancer Lett. 2024;595:216985.
    PubMed     Abstract available


  53. LUN J, Zhang Y, Yu M, Zhai W, et al
    Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis.
    Cancer Lett. 2024;593:216957.
    PubMed     Abstract available


  54. LIU Y, Shi J, Liu W, Tang Y, et al
    A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer.
    Cancer Lett. 2024;589:216641.
    PubMed     Abstract available


    April 2024
  55. YANG Y, Qi J, Hu J, Zhou Y, et al
    Lovastatin/SN38 co-loaded liposomes amplified ICB therapeutic effect via remodeling the immunologically-cold colon tumor and synergized stimulation of cGAS-STING pathway.
    Cancer Lett. 2024;588:216765.
    PubMed     Abstract available


  56. JIN Y, Jiang J, Mao W, Bai M, et al
    Treatment strategies and molecular mechanism of radiotherapy combined with immunotherapy in colorectal cancer.
    Cancer Lett. 2024;591:216858.
    PubMed     Abstract available


  57. ZHOU X, Zhang K, Wang C, Teng Y, et al
    Isthmin-1 promotes growth and progression of colorectal cancer through the interaction with EGFR and YBX-1.
    Cancer Lett. 2024 Apr 7:216868. doi: 10.1016/j.canlet.2024.216868.
    PubMed     Abstract available


  58. JIANG C, Zhou Q, Yi K, Yuan Y, et al
    Colorectal cancer initiation: Understanding early-stage disease for intervention.
    Cancer Lett. 2024 Apr 2:216831. doi: 10.1016/j.canlet.2024.216831.
    PubMed     Abstract available


    March 2024
  59. ZHOU Y, Li H, Zhang Y, Zhao E, et al
    Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer.
    Cancer Lett. 2024 Mar 29:216836. doi: 10.1016/j.canlet.2024.216836.
    PubMed     Abstract available


  60. LIN J, Zhong W, Lyu Z, Peng J, et al
    Circular RNA circTATDN3 promotes the Warburg effect and proliferation in colorectal cancer.
    Cancer Lett. 2024 Mar 26:216825. doi: 10.1016/j.canlet.2024.216825.
    PubMed     Abstract available


  61. ZHANG D, Xie J, Sun F, Xu R, et al
    Pharmacological suppression of HHLA2 glycosylation restores anti-tumor immunity in colorectal cancer.
    Cancer Lett. 2024 Mar 22:216819. doi: 10.1016/j.canlet.2024.216819.
    PubMed     Abstract available


  62. HISANO K, Mizuuchi Y, Ohuchida K, Kawata J, et al
    Microenvironmental changes in familial adenomatous polyposis during colorectal cancer carcinogenesis.
    Cancer Lett. 2024;589:216822.
    PubMed     Abstract available


  63. ZHU Z, Li M, Weng J, Li S, et al
    LncRNA GAS6-AS1 contributes to 5-fluorouracil resistance in colorectal cancer by facilitating the binding of PCBP1 with MCM3.
    Cancer Lett. 2024 Mar 21:216828. doi: 10.1016/j.canlet.2024.216828.
    PubMed     Abstract available


  64. TANG Y, Wei J, Ge X, Yu C, et al
    Intratumoral injection of interferon gamma promotes the efficacy anti-PD1 treatment in colorectal cancer.
    Cancer Lett. 2024 Mar 9:216798. doi: 10.1016/j.canlet.2024.216798.
    PubMed     Abstract available


  65. CHEN Q, Deng Y, Li Y, Chen J, et al
    Association of preoperative aspartate aminotransferase to platelet ratio index with outcomes and tumour microenvironment among colorectal cancer with liver metastases.
    Cancer Lett. 2024 Mar 6:216778. doi: 10.1016/j.canlet.2024.216778.
    PubMed     Abstract available


    January 2024
  66. LIU C, Cheng X, Han K, Hong L, et al
    A novel molecular subtyping based on multi-omics analysis for prognosis predicting in colorectal melanoma: A 16-year prospective multicentric study.
    Cancer Lett. 2024 Jan 19:216663. doi: 10.1016/j.canlet.2024.216663.
    PubMed     Abstract available


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