Retrieve available abstracts of 66 articles: HTML format
Single Articles
August 2025
SUN Z, Wu R, Liang X, Shi T, et al MLCK inhibition induces synthetic lethality in MYC-driven cancer.
Cancer Lett. 2025;625:217803. PubMedAbstract available
July 2025
BIRGERSSON M, Holm M, Gallardo-Dodd CJ, Chen B, et al Intestinal estrogen receptor beta modulates the murine colon tumor immune
microenvironment.
Cancer Lett. 2025;622:217661. PubMedAbstract available
DANEK V, Tureckova J, Huebner K, Erlenbach-Wuensch K, et al CUL4A exhibits tumor-suppressing role via regulation of HUWE1-mediated SMAD3
intracellular shuttling.
Cancer Lett. 2025;621:217663. PubMedAbstract available
June 2025
GERAKOPOULOS V, Ramos C, Muller C, Walterskirchen N, et al Single-cell transcriptomic analysis identifies tissue-specific fibroblasts as the
main modulators of myeloid cells in peritoneal metastasis of different origin.
Cancer Lett. 2025;620:217678. PubMedAbstract available
KHAN S, Karmokar A, Howells L, Britton RG, et al An old spice with new tricks: Curcumin targets adenoma and colorectal cancer
stem-like cells associated with poor survival outcomes.
Cancer Lett. 2025 Jun 19:217885. doi: 10.1016/j.canlet.2025.217885. PubMedAbstract available
YU C, Lu W, Wu J, Fang X, et al Liver metastasis or peritoneal metastasis: single-cell RNA sequencing reveals the
organotropism in colorectal cancer is driven by distinct partial-EMT processes.
Cancer Lett. 2025 Jun 17:217880. doi: 10.1016/j.canlet.2025.217880. PubMedAbstract available
May 2025
MIDDE A, Arri N, Kristian T, Mukherjee S, et al Corrigendum to "Targeting mitochondrial ribosomal protein expression by
andrographolide and melatonin for colon cancer treatment" [Cancer Lett. 619
(2025) 1-11 217647].
Cancer Lett. 2025 May 30:217784. doi: 10.1016/j.canlet.2025.217784. PubMed
ZHOU M, Guan B, Liu Y, Gu Q, et al Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles
shapes an immunosuppressive microenvironment in colorectal liver metastases by
promoting tumor stemness and neutrophil extracellular traps formation.
Cancer Lett. 2025;618:217642. PubMedAbstract available
SUN Y, Lu J, Tung Lau EY, Zeng Y, et al Fusobacterium nucleatum enhances cholesterol biosynthesis in colorectal cancer
via miR-130a-3p-mediated AMPK inhibition, a process counteracted by butyrate.
Cancer Lett. 2025 May 23:217810. doi: 10.1016/j.canlet.2025.217810. PubMedAbstract available
CHEN X, Cao Y, Zhao Y, Ma Y, et al Neurodegeneration of local sympathetic inputs promotes colorectal cancer
progression.
Cancer Lett. 2025;625:217817. PubMedAbstract available
HU D, Zhao J, Wu M, Zhou Y, et al Microbial Interactions Induce the Mutational Signature of Mismatch Repair
Deficiency in Colorectal Cancer and Associated with EPPK1 Mutations.
Cancer Lett. 2025 May 16:217807. doi: 10.1016/j.canlet.2025.217807. PubMedAbstract available
HE K, Wang H, Wu H, Li W, et al Activated Schwann cells promote tumor growth in colon cancer.
Cancer Lett. 2025;626:217791. PubMedAbstract available
LU YX, Ju HQ, Wang F, Chen LZ, et al Corrigendum to "Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses
colorectal cancer growth and metastasis" [Cancer Lett. 380 (2016) 87-97].
Cancer Lett. 2025;625:217756. PubMed
STRIPPOLI R Colorectal cancer peritoneal metastasis is promoted by tissue-specific
fibroblasts that can arise in response to various local disorders.
Cancer Lett. 2025;625:217749. PubMed
ZHOU XY, Zhang NC, Zhang XN, Sun XD, et al The carcinogenic metabolite acetaldehyde impairs cGAS activity to negatively
regulate antiviral and antitumor immunity.
Cancer Lett. 2025;617:217615. PubMedAbstract available
April 2025
ZHONG YX, Zhao HB, Lian MH, Shen JM, et al SUMOylated hnRNPM suppresses PFKFB3 phosphorylation to regulate glycolysis and
tumorigenesis.
Cancer Lett. 2025;616:217573. PubMedAbstract available
RAMOS C, Walterskirchen N, Knobl V, Zotter C, et al Colorectal cancer peritoneal metastasis is promoted by tissue-specific
fibroblasts that can arise in response to various local disorders.
Cancer Lett. 2025 Apr 12:217686. doi: 10.1016/j.canlet.2025.217686. PubMedAbstract available
HOLDFELDT A, Salerno S, Stahlberg A, Lindskog EB, et al The colorectal cancer microenvironment governs clinical behaviors and
chemotherapy response.
Cancer Lett. 2025 Apr 1:217687. doi: 10.1016/j.canlet.2025.217687. PubMed
March 2025
RICHIARDONE E, Giolito MV, Al Roumi R, Ambroise J, et al Acidosis overrides molecular heterogeneity to shape therapeutically targetable
metabolic phenotypes in colon cancers.
Cancer Lett. 2025;613:217512. PubMedAbstract available
GU Y, Ye Q, Huang X, Cao Y, et al Glycosaminoglycan modification of NRP1 exon 4-skipping variant drives colorectal
cancer metastasis via endosomal-exosomal trafficking.
Cancer Lett. 2025 Mar 27:217683. doi: 10.1016/j.canlet.2025.217683. PubMedAbstract available
MIDDE A, Arri N, Kristian T, Mukherjee S, et al Targeting mitochondrial ribosomal protein expression by andrographolide and
melatonin for colon cancer treatment.
Cancer Lett. 2025;619:217647. PubMedAbstract available
LI M, Gao X, Lin X, Zhang Y, et al Analysis of germline-somatic mutational connections in colorectal cancer reveals
differential tumorigenic patterns and a novel predictive marker for germline
mutation carriers.
Cancer Lett. 2025 Mar 19:217637. doi: 10.1016/j.canlet.2025.217637. PubMedAbstract available
GUO Z, He L, Wang W, Tian S, et al FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer
cells by regulating the autophagy-lysosomal pathway.
Cancer Lett. 2025 Mar 18:217643. doi: 10.1016/j.canlet.2025.217643. PubMedAbstract available
YAO L, Yin H, Yang C, Han S, et al GENERATING RESEARCH HYPOTHESES TO OVERCOME KEY CHALLENGES IN THE EARLY DIAGNOSIS
OF COLORECTAL CANCER - FUTURE APPLICATION OF AI.
Cancer Lett. 2025 Mar 15:217632. doi: 10.1016/j.canlet.2025.217632. PubMedAbstract available
February 2025
LOPES AL, Paulino AC, Thaumaturgo MAS, Araujo WM, et al Dietary intake of the red meat-derived glycan Neu5Gc fuels colorectal cancer
through up-regulation of Wnt signaling pathway.
Cancer Lett. 2025;616:217598. PubMedAbstract available
BAI M, Jin Y, Jin Z, Xie Y, et al Distinct Immunophenotypic Profiles and Neutrophil Heterogeneity in Colorectal
Cancer.
Cancer Lett. 2025 Feb 22:217570. doi: 10.1016/j.canlet.2025.217570. PubMedAbstract available
WANG T, Weng M, Li K, Li G, et al LIN28B enhances the chemosensitivity of colon cancer cells via inducing genomic
instability by upsetting the balance between the production and removal of
reactive oxygen species.
Cancer Lett. 2025 Feb 20:217572. doi: 10.1016/j.canlet.2025.217572. PubMedAbstract available
ZHUO FF, Li L, Liu TT, Liang XM, et al Corrigendum to "Lycorine promotes IDH1 acetylation to induce mitochondrial
dynamics imbalance in colorectal cancer cells" [Canc. Lett. 573 (2023) 216364].
Cancer Lett. 2025 Feb 9:217533. doi: 10.1016/j.canlet.2025.217533. PubMed
January 2025
BAI X, Liu B, Fan D, Lu Y, et al Modulating the gut microbiota: A novel perspective in colorectal cancer
treatment.
Cancer Lett. 2025 Jan 11:217459. doi: 10.1016/j.canlet.2025.217459. PubMedAbstract available
ZHAN Y, Sun D, Gao J, Gao Q, et al Single-cell Transcriptomics Reveals Intratumor Heterogeneity and the Potential
Roles of Cancer Stem Cells and myCAFs in Colorectal Cancer Liver Metastasis and
Recurrence.
Cancer Lett. 2025 Jan 11:217452. doi: 10.1016/j.canlet.2025.217452. PubMedAbstract available
December 2024
XU C, Jiang C, Tian Y, Liu Y, et al Nervous system in colorectal cancer.
Cancer Lett. 2024 Dec 24:217431. doi: 10.1016/j.canlet.2024.217431. PubMedAbstract available
ZHOU Y, Lei T, Tang Z, Guo P, et al Increased phosphorylation of AMPKalpha1 S485 in colorectal cancer and identification
of PKCalpha as a responsible kinase.
Cancer Lett. 2024 Dec 24:217418. doi: 10.1016/j.canlet.2024.217418. PubMedAbstract available
MALIER M, Laverriere MH, Henry M, Yakoubi M, et al Tumor-associated macrophages confer resistance to chemotherapy
(Trifluridine/Tipiracil) in digestive cancers by overexpressing thymidine
phosphorylase.
Cancer Lett. 2024;606:217307. PubMedAbstract available
November 2024
DONG Z, Ojha A, Barlow L, Luo L, et al The eIF3a translational control axis in the Wnt/beta-catenin signaling pathway and
colon tumorigenesis.
Cancer Lett. 2024;605:217303. PubMedAbstract available
O'BRIEN RM, Meltzer S, Buckley CE, Heeran AB, et al Complement is increased in treatment resistant rectal cancer and modulates
radioresistance.
Cancer Lett. 2024;604:217253. PubMedAbstract available
YAO B, Wu J Letter to the editor on 'A deep neural network predictor to predict the
sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer'.
Cancer Lett. 2024;604:217212. PubMed
September 2024
TAN YT, Li T, Wang RB, Liu ZK, et al WTAP weakens oxaliplatin chemosensitivity of colorectal cancer by preventing
PANoptosis.
Cancer Lett. 2024;604:217254. PubMedAbstract available
YANG H, Gong C, Wu Y, Xie X, et al LncRNA SNHG1 facilitates colorectal cancer cells metastasis by recruiting HNRNPD
protein to stabilize SERPINA3 mRNA.
Cancer Lett. 2024 Sep 2:217217. doi: 10.1016/j.canlet.2024.217217. PubMedAbstract available
August 2024
LI M, Xie Y, Zhang J, Zhou X, et al Intratumoral injection of mRNA encoding survivin in combination with STAT3
inhibitor stattic enhances antitumor effects.
Cancer Lett. 2024;598:217111. PubMedAbstract available
ZHOU L, Wen R, Bai C, Li Z, et al Spatial transcriptomic revealed intratumor heterogeneity and cancer stem cell
enrichment in colorectal cancer metastasis.
Cancer Lett. 2024 Aug 17:217181. doi: 10.1016/j.canlet.2024.217181. PubMedAbstract available
HAN Y, Pu Y, Liu X, Liu Z, et al YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer
progression in a m6A-dependent manner.
Cancer Lett. 2024 Aug 14:217186. doi: 10.1016/j.canlet.2024.217186. PubMedAbstract available
LING T, Dai Z, Wang H, Kien TT, et al Serotonylation in tumor-associated fibroblasts contributes to the tumor-promoting
roles of serotonin in colorectal cancer.
Cancer Lett. 2024 Aug 1:217150. doi: 10.1016/j.canlet.2024.217150. PubMedAbstract available
July 2024
KONG WS, Li JJ, Deng YQ, Ju HQ, et al Immunomodulatory molecules in colorectal cancer liver metastasis.
Cancer Lett. 2024;598:217113. PubMedAbstract available
ZHU N, Ding Y, Mi M, Yang J, et al Loss-of-function mutation of REV1 (p.R704Q) mediates cetuximab primary resistance
by activating autophagy in RAS-wild type metastatic colorectal cancer.
Cancer Lett. 2024 Jul 3:217103. doi: 10.1016/j.canlet.2024.217103. PubMedAbstract available
LUO XJ, Lu YX, Wang Y, Huang R, et al M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through
PTBP1.
Cancer Lett. 2024 Jul 2:217085. doi: 10.1016/j.canlet.2024.217085. PubMedAbstract available
RICHIARDONE E, Al Roumi R, Lardinois F, Giolito MV, et al MCT1-dependent lactate recycling is a metabolic vulnerability in colorectal
cancer cells upon acquired resistance to anti-EGFR targeted therapy.
Cancer Lett. 2024 Jul 2:217091. doi: 10.1016/j.canlet.2024.217091. PubMedAbstract available
CHEN Q, Chen J, Deng Y, Bi X, et al Personalized prediction of postoperative complication and survival among
Colorectal Liver Metastases Patients Receiving Simultaneous Resection using
machine learning approaches: A multi-center study.
Cancer Lett. 2024;593:216967. PubMedAbstract available
HUANG C, Tan H, Wang J, Huang L, et al beta-hydroxybutyrate restrains colitis-associated tumorigenesis by inhibiting
HIF-1alpha-mediated angiogenesis.
Cancer Lett. 2024;593:216940. PubMedAbstract available
June 2024
HANG D, Sun D, Du L, Huang J, et al Development and evaluation of a risk prediction tool for risk-adapted screening
of colorectal cancer in China.
Cancer Lett. 2024;597:217057. PubMedAbstract available
YUAN M, Zhang C, Chen S, Ye S, et al PDP1 promotes KRAS mutant colorectal cancer progression by serving as a scaffold
for BRAF and MEK1.
Cancer Lett. 2024;597:217007. PubMedAbstract available
BIAN Y, Xu S, Gao Z, Ding J, et al m(6)A modification of lncRNA ABHD11-AS1 promotes colorectal cancer progression
and inhibits ferroptosis through TRIM21/IGF2BP2/ FOXM1 positive feedback loop.
Cancer Lett. 2024 Jun 3:217004. doi: 10.1016/j.canlet.2024.217004. PubMedAbstract available
May 2024
AGORKU DJ, Bosio A, Alves F, Strobel P, et al Colorectal cancer-associated fibroblasts inhibit effector T cells via NECTIN2
signaling.
Cancer Lett. 2024;595:216985. PubMedAbstract available
LUN J, Zhang Y, Yu M, Zhai W, et al Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis.
Cancer Lett. 2024;593:216957. PubMedAbstract available
LIU Y, Shi J, Liu W, Tang Y, et al A deep neural network predictor to predict the sensitivity of neoadjuvant
chemoradiotherapy in locally advanced rectal cancer.
Cancer Lett. 2024;589:216641. PubMedAbstract available
April 2024
YANG Y, Qi J, Hu J, Zhou Y, et al Lovastatin/SN38 co-loaded liposomes amplified ICB therapeutic effect via
remodeling the immunologically-cold colon tumor and synergized stimulation of
cGAS-STING pathway.
Cancer Lett. 2024;588:216765. PubMedAbstract available
JIN Y, Jiang J, Mao W, Bai M, et al Treatment strategies and molecular mechanism of radiotherapy combined with
immunotherapy in colorectal cancer.
Cancer Lett. 2024;591:216858. PubMedAbstract available
ZHOU X, Zhang K, Wang C, Teng Y, et al Isthmin-1 promotes growth and progression of colorectal cancer through the
interaction with EGFR and YBX-1.
Cancer Lett. 2024 Apr 7:216868. doi: 10.1016/j.canlet.2024.216868. PubMedAbstract available
JIANG C, Zhou Q, Yi K, Yuan Y, et al Colorectal cancer initiation: Understanding early-stage disease for intervention.
Cancer Lett. 2024 Apr 2:216831. doi: 10.1016/j.canlet.2024.216831. PubMedAbstract available
March 2024
ZHOU Y, Li H, Zhang Y, Zhao E, et al Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation
and tumor cell-intrinsic interferon response in colorectal cancer.
Cancer Lett. 2024 Mar 29:216836. doi: 10.1016/j.canlet.2024.216836. PubMedAbstract available
LIN J, Zhong W, Lyu Z, Peng J, et al Circular RNA circTATDN3 promotes the Warburg effect and proliferation in
colorectal cancer.
Cancer Lett. 2024 Mar 26:216825. doi: 10.1016/j.canlet.2024.216825. PubMedAbstract available
ZHANG D, Xie J, Sun F, Xu R, et al Pharmacological suppression of HHLA2 glycosylation restores anti-tumor immunity
in colorectal cancer.
Cancer Lett. 2024 Mar 22:216819. doi: 10.1016/j.canlet.2024.216819. PubMedAbstract available
HISANO K, Mizuuchi Y, Ohuchida K, Kawata J, et al Microenvironmental changes in familial adenomatous polyposis during colorectal
cancer carcinogenesis.
Cancer Lett. 2024;589:216822. PubMedAbstract available
ZHU Z, Li M, Weng J, Li S, et al LncRNA GAS6-AS1 contributes to 5-fluorouracil resistance in colorectal cancer by
facilitating the binding of PCBP1 with MCM3.
Cancer Lett. 2024 Mar 21:216828. doi: 10.1016/j.canlet.2024.216828. PubMedAbstract available
TANG Y, Wei J, Ge X, Yu C, et al Intratumoral injection of interferon gamma promotes the efficacy anti-PD1
treatment in colorectal cancer.
Cancer Lett. 2024 Mar 9:216798. doi: 10.1016/j.canlet.2024.216798. PubMedAbstract available
CHEN Q, Deng Y, Li Y, Chen J, et al Association of preoperative aspartate aminotransferase to platelet ratio index
with outcomes and tumour microenvironment among colorectal cancer with liver
metastases.
Cancer Lett. 2024 Mar 6:216778. doi: 10.1016/j.canlet.2024.216778. PubMedAbstract available
January 2024
LIU C, Cheng X, Han K, Hong L, et al A novel molecular subtyping based on multi-omics analysis for prognosis
predicting in colorectal melanoma: A 16-year prospective multicentric study.
Cancer Lett. 2024 Jan 19:216663. doi: 10.1016/j.canlet.2024.216663. PubMedAbstract available