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	COVID-19: Daily Top 10 Papers

Colorectal Neoplasms

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July 2021
1. WANG H, Zhu Y, Chen H, Yang N, et al
   Colorectal cancer risk variant rs7017386 modulates two oncogenic lncRNAs expression via ATF1-mediated long-range chromatin loop.
   Cancer Lett. 2021;518:140-151.
   PubMed     Abstract available
   
   
   
2. STADLER M, Pudelko K, Biermeier A, Walterskirchen N, et al
   Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages.
   Cancer Lett. 2021;520:184-200.
   PubMed     Abstract available
   
   
   
3. JING Z, He X, Jia Z, Sa Y, et al
   NCAPD2 inhibits autophagy by regulating Ca(2+)/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer.
   Cancer Lett. 2021;520:26-37.
   PubMed     Abstract available
   
   
   June 2021
4. ZHANG H, Chi J, Hu J, Ji T, et al
   Intracellular AGR2 transduces PGE2 stimuli to promote epithelial-mesenchymal transition and metastasis of colorectal cancer.
   Cancer Lett. 2021 Jun 30. pii: S0304-3835(21)00310.
   PubMed     Abstract available
   
   
   
5. GE C, Wang Y, Feng Y, Wang S, et al
   Suppression of oxidative phosphorylation and IDH2 sensitizes colorectal cancer to a naphthalimide derivative and mitoxantrone.
   Cancer Lett. 2021 Jun 21. pii: S0304-3835(21)00300.
   PubMed     Abstract available
   
   
   
6. LI W, Ma Y, He L, Li H, et al
   Protease-activated receptor 2 stabilizes Bcl-xL and regulates EGFR-targeted therapy response in colorectal cancer.
   Cancer Lett. 2021 Jun 4. pii: S0304-3835(21)00271.
   PubMed     Abstract available
   
   
   
7. SUI Q, Peng J, Han K, Lin J, et al
   Corrigendum to "Voltage-gated sodium channel Nav1.5 promotes tumor progression and enhances chemosensitivity to 5-fluorouracil in colorectal cancer" [Canc. Lett. 500 (2021) 119-131].
   Cancer Lett. 2021;516:57-60.
   PubMed    
   
   
   May 2021
8. LI J, Tian L, Jing Z, Guo Z, et al
   Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis.
   Cancer Lett. 2021;516:13-27.
   PubMed     Abstract available
   
   
   
9. CHEN J, Wang H, Jia L, He J, et al
   Bufalin targets the SRC-3/MIF pathway in chemoresistant cells to regulate M2 macrophage polarization in colorectal cancer.
   Cancer Lett. 2021 May 14. pii: S0304-3835(21)00223.
   PubMed     Abstract available
   
   
   March 2021
10. NICOLAZZO C, Barault L, Caponnetto S, De Renzi G, et al
    True conversions from RAS mutant to RAS wild-type in circulating tumor DNA from metastatic colorectal cancer patients as assessed by methylation and mutational signature.
    Cancer Lett. 2021;507:89-96.
    PubMed     Abstract available
    
    
    February 2021
11. YANG Y, Yan X, Li X, Ma Y, et al
    Invited review article: Cancer letters long non-coding RNAs in colorectal cancer: Novel oncogenic mechanisms and promising clinical applications.
    Cancer Lett. 2021 Feb 9. pii: S0304-3835(21)00025.
    PubMed     Abstract available
    
    
    January 2021
12. SI W, Zhou B, Xie W, Li H, et al
    Angiogenic factor AGGF1 acts as a tumor suppressor by modulating p53 post-transcriptional modifications and stability via MDM2.
    Cancer Lett. 2021;497:28-40.
    PubMed     Abstract available
    
    
    
13. OH Y, Jung HR, Min S, Kang J, et al
    Targeting antioxidant enzymes enhances the therapeutic efficacy of the BCL-XL inhibitor ABT-263 in KRAS-mutant colorectal cancers.
    Cancer Lett. 2021;497:123-136.
    PubMed     Abstract available
    
    
    
14. WAN J, Wu Y, Huang L, Tian Y, et al
    ILC2-derived IL-9 inhibits colorectal cancer progression by activating CD8(+) T cells.
    Cancer Lett. 2021 Jan 8. pii: S0304-3835(21)00011.
    PubMed     Abstract available
    
    
    
15. BAI D, Wu Y, Deol P, Nobumori Y, et al
    Palmitic acid negatively regulates tumor suppressor PTEN through T366 phosphorylation and protein degradation.
    Cancer Lett. 2021;496:127-133.
    PubMed     Abstract available
    
    
    December 2020
16. HUANG X, Zhu X, Yu Y, Zhu W, et al
    Dissecting miRNA signature in colorectal cancer progression and metastasis.
    Cancer Lett. 2020 Dec 29. pii: S0304-3835(20)30685.
    PubMed     Abstract available
    
    
    
17. LIN R, Han C, Ding Z, Shi H, et al
    Knock down of BMSC-derived Wnt3a or its antagonist analogs attenuate colorectal carcinogenesis induced by chronic Fusobacterium nucleatum infection.
    Cancer Lett. 2020;495:165-179.
    PubMed     Abstract available
    
    
    
18. SUI Q, Peng J, Han K, Lin J, et al
    Voltage-gated sodium channel Nav1.5 promotes tumor progression and enhances chemosensitivity to 5-fluorouracil in colorectal cancer.
    Cancer Lett. 2020 Dec 15. pii: S0304-3835(20)30667.
    PubMed     Abstract available
    
    
    
19. PENG W, Zhang C, Peng J, Huang Y, et al
    Lnc-FAM84B-4 acts as an oncogenic lncRNA by interacting with protein hnRNPK to restrain MAPK phosphatases-DUSP1 expression.
    Cancer Lett. 2020;494:94-106.
    PubMed     Abstract available
    
    
    November 2020
20. JAO TM, Fang WH, Ciou SC, Yu SL, et al
    PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer.
    Cancer Lett. 2020 Nov 30. pii: S0304-3835(20)30610.
    PubMed     Abstract available
    
    
    
21. HONG EH, Cho J, Ahn JH, Kwon BE, et al
    Plasmacytoid dendritic cells regulate colitis-associated tumorigenesis by controlling myeloid-derived suppressor cell infiltration.
    Cancer Lett. 2020;493:102-112.
    PubMed     Abstract available
    
    
    
22. TAO H, Cheng L, Liu L, Wang H, et al
    A PD-1 peptide antagonist exhibits potent anti-tumor and immune regulatory activity.
    Cancer Lett. 2020;493:91-101.
    PubMed     Abstract available
    
    
    
23. XIAO Q, Lu W, Kong X, Shao YW, et al
    Alterations of circulating bacterial DNA in colorectal cancer and adenoma: A proof-of-concept study.
    Cancer Lett. 2020 Nov 26. pii: S0304-3835(20)30627.
    PubMed     Abstract available
    
    
    
24. DUROSS AN, Landry MR, Thomas CR, Neufeld MJ, et al
    Fucoidan-coated nanoparticles target radiation-induced P-selectin to enhance chemoradiotherapy in murine colorectal cancer.
    Cancer Lett. 2020 Nov 21. pii: S0304-3835(20)30618.
    PubMed     Abstract available
    
    
    
25. HASES L, Indukuri R, Birgersson M, Nguyen-Vu T, et al
    Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes.
    Cancer Lett. 2020;492:54-62.
    PubMed     Abstract available
    
    
    October 2020
26. FENG M, Zhao Z, Yang M, Ji J, et al
    T-cell-based immunotherapy in colorectal cancer.
    Cancer Lett. 2020 Oct 29. pii: S0304-3835(20)30574.
    PubMed     Abstract available
    
    
    
27. LI N, Tang J, Yang J, Zhu B, et al
    Tumor perfusion enhancement by ultrasound stimulated microbubbles potentiates PD-L1 blockade of MC38 colon cancer in mice.
    Cancer Lett. 2020 Oct 28. pii: S0304-3835(20)30579.
    PubMed     Abstract available
    
    
    
28. YU Z, Du J, Zhao Y, Gao Y, et al
    A novel kinase inhibitor, LZT-106, downregulates Mcl-1 and sensitizes colorectal cancer cells to BH3 mimetic ABT-199 by targeting CDK9 and GSK-3beta signaling.
    Cancer Lett. 2020 Oct 28. pii: S0304-3835(20)30499.
    PubMed     Abstract available
    
    
    
29. YORITA N, Yuge R, Takigawa H, Atsushi O, et al
    Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model.
    Cancer Lett. 2020 Oct 28. pii: S0304-3835(20)30575.
    PubMed     Abstract available
    
    
    
30. QIAO S, Lv C, Tao Y, Miao Y, et al
    Arctigenin disrupts NLRP3 inflammasome assembly in colonic macrophages via downregulating fatty acid oxidation to prevent colitis-associated cancer.
    Cancer Lett. 2020;491:162-179.
    PubMed     Abstract available
    
    
    
31. ROBRAHN L, Jiao L, Cramer T
    Barrier integrity and chronic inflammation mediated by HIF-1 impact on intestinal tumorigenesis.
    Cancer Lett. 2020;490:186-192.
    PubMed     Abstract available
    
    
    
32. ZHENG X, Liu J, Li X, Tian R, et al
    Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
    Cancer Lett. 2020 Oct 8. pii: S0304-3835(20)30507.
    PubMed     Abstract available
    
    
    
33. SASAKI M, Miyoshi N, Fujino S, Saso K, et al
    The meiosis-specific cohesin component stromal antigen 3 promotes cell migration and chemotherapeutic resistance in colorectal cancer.
    Cancer Lett. 2020 Oct 8. pii: S0304-3835(20)30504.
    PubMed     Abstract available
    
    
    September 2020
34. ZHAO H, Yan C, Hu Y, Mu L, et al
    Differentiated cancer cell-originated lactate promotes the self-renewal of cancer stem cells in patient-derived colorectal cancer organoids.
    Cancer Lett. 2020 Sep 5. pii: S0304-3835(20)30458.
    PubMed     Abstract available
    
    
    
35. WU Q, Liu W, Wang J, Zhu L, et al
    Exosomal noncoding RNAs in colorectal cancer.
    Cancer Lett. 2020 Sep 5. pii: S0304-3835(20)30451.
    PubMed     Abstract available
    
    
    
36. ROTHKAMM K, Christiansen S, Rieckmann T, Horn M, et al
    Radiosensitisation and enhanced tumour growth delay of colorectal cancer cells by sustained treatment with trifluridine/tipiracil and X-rays.
    Cancer Lett. 2020;493:179-188.
    PubMed     Abstract available
    
    
    July 2020
37. QI S, Perrino S, Miao X, Lamarche-Vane N, et al
    The chemokine CCL7 regulates invadopodia maturation and MMP-9 mediated collagen degradation in liver-metastatic carcinoma cells.
    Cancer Lett. 2020;483:98-113.
    PubMed     Abstract available
    
    
    
38. ZHANG Y, Wang S, Lai Q, Fang Y, et al
    Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-beta1 positive feedback loop.
    Cancer Lett. 2020 Jul 27. pii: S0304-3835(20)30380.
    PubMed     Abstract available
    
    
    June 2020
39. WU H, Singh S, Xie Z, Li X, et al
    Landscape characterization of chimeric RNAs in colorectal cancer.
    Cancer Lett. 2020 Jun 10. pii: S0304-3835(20)30299.
    PubMed     Abstract available
    
    
    May 2020
40. SATAPATHY SR, Sjolander A
    Cysteinyl leukotriene receptor 1 promotes 5-fluorouracil resistance and resistance-derived stemness in colon cancer cells.
    Cancer Lett. 2020 May 28. pii: S0304-3835(20)30285.
    PubMed     Abstract available
    
    
    
41. YAN S, Wang H, Chen X, Liang C, et al
    MiR-182-5p inhibits colon cancer tumorigenesis, angiogenesis, and lymphangiogenesis by directly downregulating VEGF-C.
    Cancer Lett. 2020 May 27. pii: S0304-3835(20)30215.
    PubMed     Abstract available
    
    
    
42. HOU Z, Sun L, Xu F, Hu F, et al
    Blocking histone methyltransferase SETDB1 inhibits tumorigenesis and enhances cetuximab sensitivity in colorectal cancer.
    Cancer Lett. 2020;487:63-73.
    PubMed     Abstract available
    
    
    
43. KIYASU Y, Kawada K, Hirai H, Ogawa R, et al
    Disruption of CCR1-mediated myeloid cell accumulation suppresses colorectal cancer progression in mice.
    Cancer Lett. 2020 May 27. pii: S0304-3835(20)30290.
    PubMed     Abstract available
    
    
    April 2020
44. TIAN H, Kang Y, Song X, Xu Y, et al
    PDL1-targeted vaccine exhibits potent antitumor activity by simultaneously blocking PD1/PDL1 pathway and activating PDL1-specific immune responses.
    Cancer Lett. 2020;476:170-182.
    PubMed     Abstract available
    
    
    
45. LU C, Klement JD, Yang D, Albers T, et al
    SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth.
    Cancer Lett. 2020;476:87-96.
    PubMed     Abstract available
    
    
    March 2020
46. WANG Y, Lu JH, Wang F, Wang YN, et al
    Inhibition of fatty acid catabolism augments the efficacy of oxaliplatin-based chemotherapy in gastrointestinal cancers.
    Cancer Lett. 2020;473:74-89.
    PubMed     Abstract available
    
    
    
47. TAM BY, Chiu K, Chung H, Bossard C, et al
    The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models.
    Cancer Lett. 2020;473:186-197.
    PubMed     Abstract available
    
    
    
48. ZHAO C, Qiu S, He J, Peng Y, et al
    Prodigiosin impairs autophagosome-lysosome fusion that sensitizes colorectal cancer cells to 5-fluorouracil-induced cell death.
    Cancer Lett. 2020 Mar 14. pii: S0304-3835(20)30129.
    PubMed     Abstract available
    
    
    
49. LAI CH, Chen RY, Hsieh HP, Tsai SJ, et al
    A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis.
    Cancer Lett. 2020;472:97-107.
    PubMed     Abstract available
    
    
    
50. LEE SY, Yang SB, Choi YM, Oh SJ, et al
    Heat-killed Mycobacterium paragordonae therapy exerts an anti-cancer immune response via enhanced immune cell mediated oncolytic activity in xenograft mice model.
    Cancer Lett. 2020;472:142-150.
    PubMed     Abstract available
    
    
    February 2020
51. FAN M, Ma X, Wang F, Zhou Z, et al
    MicroRNA-30b-5p functions as a metastasis suppressor in colorectal cancer by targeting Rap1b.
    Cancer Lett. 2020 Feb 26. pii: S0304-3835(20)30084.
    PubMed     Abstract available
    
    
    
52. QIN Y, Shembrey C, Smith J, Paquet-Fifield S, et al
    Laminin 521 enhances self-renewal via Stat3 activation and promotes tumor progression in Colorectal Cancer.
    Cancer Lett. 2020 Feb 24. pii: S0304-3835(20)30095.
    PubMed     Abstract available
    
    
    
53. GAO Q, Li XX, Xu YM, Zhang JZ, et al
    IRE1alpha-targeting Downregulates ABC Transporters and Overcomes Drug Resistance of Colon Cancer Cells.
    Cancer Lett. 2020 Feb 12. pii: S0304-3835(20)30069.
    PubMed     Abstract available
    
    
    
54. XIAO YW, Zhong JN, Zhong BY, Huang JY, et al
    Exosomes as potential sources of biomarkers in colorectal cancer.
    Cancer Lett. 2020 Feb 7. pii: S0304-3835(20)30047.
    PubMed     Abstract available
    
    
    January 2020
55. KE Z, Wang C, Wu T, Wang W, et al
    PAR2 deficiency enhances myeloid cell-mediated immunosuppression and promotes colitis-associated tumorigenesis.
    Cancer Lett. 2020;469:437-446.
    PubMed     Abstract available
    
    
    
56. WANG D, Wang X, Si M, Yang J, et al
    Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages.
    Cancer Lett. 2020 Jan 10. pii: S0304-3835(20)30013.
    PubMed     Abstract available
    
    
    December 2019
57. LIU C, Zhao Y, Wang J, Yang Y, et al
    FoxO3 reverses 5-fluorouracil resistance in human colorectal cancer cells by inhibiting the Nrf2/TR1 signaling pathway.
    Cancer Lett. 2019 Dec 4. pii: S0304-3835(19)30608.
    PubMed     Abstract available
    
    
    October 2019
58. EILERTSEN IA, Moosavi SH, Stromme JM, Nesbakken A, et al
    Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer.
    Cancer Lett. 2019 Oct 30. pii: S0304-3835(19)30543.
    PubMed     Abstract available
    
    
    
59. EYLEM CC, Yilmaz M, Derkus B, Nemutlu E, et al
    Untargeted Multi-Omic Analysis of Colorectal Cancer-Specific Exosomes Reveals Joint Pathways of Colorectal Cancer in both Clinical Samples and Cell Culture.
    Cancer Lett. 2019 Oct 25. pii: S0304-3835(19)30541.
    PubMed     Abstract available
    
    
    
60. LIU Z, Xie Y, Xiong Y, Liu S, et al
    TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages.
    Cancer Lett. 2019 Oct 17. pii: S0304-3835(19)30517.
    PubMed     Abstract available
    
    
    
61. LU YX, Ju HQ, Wang F, Chen LZ, et al
    Corrigendum to "Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis" [Cancer Lett. 380 (2016) 87-97].
    Cancer Lett. 2019 Oct 14. pii: S0304-3835(19)30492.
    PubMed    
    
    
    
62. ZHANG Y, Song J, Zhao Z, Yang M, et al
    Single-cell transcriptome analysis reveals tumor immune microenvironment heterogenicity and granulocytes enrichment in colorectal cancer liver metastases.
    Cancer Lett. 2019 Oct 11. pii: S0304-3835(19)30513.
    PubMed     Abstract available
    
    
    September 2019
63. CHEN S, Yue T, Huang Z, Zhu J, et al
    Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells.
    Cancer Lett. 2019 Sep 19. pii: S0304-3835(19)30470.
    PubMed     Abstract available
    
    
    June 2019
64. CHENG X, Feng H, Wu H, Jin Z, et al
    Corrigendum to "Targeting autophagy enhances apatinib-induced apoptosis via endoplasmic reticulum stress for human colorectal cancer" [Cancer Lett. 431 (2018) 105-114].
    Cancer Lett. 2019 Jun 4. pii: S0304-3835(19)30315.
    PubMed    
    
    
    May 2019
65. ZHANG S, Cao L, Li Z, Qu D, et al
    Metabolic reprogramming links chronic intestinal inflammation and the oncogenic transformation in colorectal tumorigenesis.
    Cancer Lett. 2019;450:123-131.
    PubMed     Abstract available
    
    
    
66. KIM CW, Oh ET, Kim JM, Park JS, et al
    Corrigendum to "Hypoxia-induced microRNA-590-5p promotes colorectal cancer progression by modulating matrix metalloproteinase activity" [Cancer Lett. 416 (2018) 31-41].
    Cancer Lett. 2019 May 4. pii: S0304-3835(19)30255.
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67. LEE WK, Thevenod F
    Oncogenic PITX2 facilitates tumor cell drug resistance by inverse regulation of hOCT3/SLC22A3 and ABC drug transporters in colon and kidney cancers.
    Cancer Lett. 2019;449:237-251.
    PubMed     Abstract available
    
    
    April 2019
68. WANG Q, Dai L, Wang Y, Deng J, et al
    Targeted demethylation of the SARI promotor impairs colon tumour growth.
    Cancer Lett. 2019;448:132-143.
    PubMed     Abstract available
    
    
    
69. HILLERT EK, Brnjic S, Zhang X, Mazurkiewicz M, et al
    Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation.
    Cancer Lett. 2019;448:70-83.
    PubMed     Abstract available
    
    
    
70. TIAN X, Liu K, Zu X, Ma F, et al
    3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.
    Cancer Lett. 2019;448:20-30.
    PubMed     Abstract available
    
    
    
71. HUANG Q, Chen Z, Cheng P, Huang Y, et al
    LYRM2 directly Regulates Complex I Activity to Support Tumor Growth in Colorectal Cancer by Oxidative Phosphorylation.
    Cancer Lett. 2019 Apr 17. pii: S0304-3835(19)30252.
    PubMed     Abstract available
    
    
    
72. HE D, Ma Z, Fang C, Ding J, et al
    Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer.
    Cancer Lett. 2019;454:53-65.
    PubMed     Abstract available
    
    
    
73. ZHANG R, Li X, Wei L, Qin Y, et al
    Lemur tyrosine kinase 2 acts as a positive regulator of NF-kappaB activation and colon cancer cell proliferation.
    Cancer Lett. 2019;454:70-77.
    PubMed     Abstract available
    
    
    March 2019
74. GAO T, Hu Q, Hu X, Lei Q, et al
    Novel selective TOPK inhibitor SKLB-C05 inhibits colorectal carcinoma growth and metastasis.
    Cancer Lett. 2019;445:11-23.
    PubMed     Abstract available
    
    
    
75. YANG J, Xu WW, Hong P, Ye F, et al
    Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction.
    Cancer Lett. 2019 Mar 11. pii: S0304-3835(19)30149.
    PubMed     Abstract available
    
    
    
76. WANG Q, Feng Y, Peng W, Ji D, et al
    Long noncoding RNA Linc02023 regulates PTEN stability and suppresses tumorigenesis of colorectal cancer in a PTEN-dependent pathway.
    Cancer Lett. 2019 Mar 5. pii: S0304-3835(19)30127.
    PubMed     Abstract available
    
    
    February 2019
77. ULLMANN P, Nurmik M, Schmitz M, Rodriguez F, et al
    Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity.
    Cancer Lett. 2019 Feb 18. pii: S0304-3835(19)30108.
    PubMed     Abstract available
    
    
    
78. WANG H, Jiang H, Corbet C, de Mey S, et al
    Piperlongumine increases sensitivity of colorectal cancer cells to radiation: involvement of ROS production via dual inhibition of glutathione and thioredoxin systems.
    Cancer Lett. 2019 Feb 18. pii: S0304-3835(19)30112.
    PubMed     Abstract available
    
    
    
79. WEI F, Zhang T, Deng SC, Wei JC, et al
    PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways.
    Cancer Lett. 2019 Feb 15. pii: S0304-3835(19)30100.
    PubMed     Abstract available
    
    
    
80. YU L, Dong L, Wang Y, Liu L, et al
    Reversible Regulation of SATB1 Ubiquitination by USP47 and SMURF2 Mediates Colon Cancer Cell Proliferation and Tumor Progression.
    Cancer Lett. 2019 Feb 8. pii: S0304-3835(19)30068.
    PubMed     Abstract available
    
    
    
81. DE VERA AA, Gupta P, Lei Z, Liao D, et al
    Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo.
    Cancer Lett. 2019;442:91-103.
    PubMed     Abstract available
    
    
    January 2019
82. BELHADJ S, Moutinho C, Mur P, Setien F, et al
    Germline variation in O(6)-Methylguanine-DNA Methyltransferase (MGMT) as cause of hereditary colorectal cancer.
    Cancer Lett. 2019 Jan 21. pii: S0304-3835(19)30031.
    PubMed     Abstract available
    
    
    
83. JEONG S, Yun HK, Jeong YA, Jo MJ, et al
    Cannabidiol-induced apoptosis is mediated by activation of Noxa in human colorectal cancer cells.
    Cancer Lett. 2019 Jan 17. pii: S0304-3835(19)30023.
    PubMed     Abstract available
    
    
    
84. JIN F, Yang R, Wei Y, Wang D, et al
    HIF-1alpha-induced miR-23a approximately 27a approximately 24 cluster promotes colorectal cancer progression via reprogramming metabolism.
    Cancer Lett. 2019;440-441:211-222.
    PubMed     Abstract available
    
    
    
85. KIM YJ, Lee JH, Jin S, Kim JH, et al
    Primate-specific miR-944 activates p53-dependent tumor suppression in human colorectal cancers.
    Cancer Lett. 2019;440-441:168-179.
    PubMed     Abstract available
    
    
    
86. VIDIMAR V, Licona C, Ceron-Camacho R, Guerin E, et al
    A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53.
    Cancer Lett. 2019;440-441:145-155.
    PubMed     Abstract available
    
    
    
87. JI N, Yang Y, Cai CY, Lei ZN, et al
    Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells.
    Cancer Lett. 2019;440-441:82-93.
    PubMed     Abstract available
    
    
    December 2018
88. TAKEDA S, Shigeyasu K, Okugawa Y, Yoshida K, et al
    Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer.
    Cancer Lett. 2018 Dec 21. pii: S0304-3835(18)30724.
    PubMed     Abstract available
    
    
    November 2018
89. DENG S, Deng Q, Zhang Y, Ye H, et al
    Non-platelet-derived CXCL4 differentially regulates cytotoxic and regulatory T cells through CXCR3 to suppress the immune response to colon cancer.
    Cancer Lett. 2018 Nov 24. pii: S0304-3835(18)30683.
    PubMed     Abstract available
    
    
    
90. DING C, Tang W, Wu H, Fan X, et al
    The PEAK1-PPP1R12B axis inhibits tumor growth and metastasis by regulating Grb2/PI3K/Akt signalling in colorectal cancer.
    Cancer Lett. 2018 Nov 22. pii: S0304-3835(18)30678.
    PubMed     Abstract available
    
    
    
91. TREMBLE LF, O'Brien MA, Forde PF
    Electrochemotherapy with cisplatin increases survival and induces immunogenic responses in murine models of lung cancer and colorectal cancer.
    Cancer Lett. 2018 Nov 22. pii: S0304-3835(18)30680.
    PubMed     Abstract available
    
    
    October 2018
92. DENG Q, Geng Y, Zhao L, Li R, et al
    NLRP3 inflammasomes in macrophages drive colorectal cancer metastasis to the liver.
    Cancer Lett. 2018;442:21-30.
    PubMed     Abstract available
    
    
    
93. ZHANG YK, Wang YJ, Lei ZN, Zhang GN, et al
    Regorafenib antagonizes BCRP-mediated multidrug resistance in colon cancer.
    Cancer Lett. 2018 Oct 27. pii: S0304-3835(18)30647.
    PubMed     Abstract available
    
    
    
94. ZHANG J, Ren P, Xu D, Liu X, et al
    Human UTP14a promotes colorectal cancer progression by forming a positive regulation loop with c-Myc.
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